Best TWAS P=3.9e-11 · Best GWAS P=4.92e-12 conditioned to 0.00148
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | TEX15 | 0.05 | 0.03 | enet | 9 | 0.02 | 6.8e-04 | 5.8 | 6.6 | 3.9e-11 | 0.70 | 0.06 | 0.93 | TRUE |
2 | ROSMAP | Brain Pre-frontal Cortex | TEX15 | 0.05 | 0.04 | lasso | 4 | 0.04 | 2.7e-06 | 5.6 | 5.2 | 1.9e-07 | 0.66 | 0.44 | 0.56 | FALSE |