[Hub]/) : Traits : Leg fat percentage (right) : ← →

chr11:26,818,083-29,054,545

Best TWAS P=1.37e-18 · Best GWAS P=5.13e-23 conditioned to 0.000117

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	LIN7C	0.08	0.06	lasso	1	0.04	4.1e-04	8.80	8.8	1.4e-18	0.65	0.67	0.22	TRUE
2	GTEx	Brain Putamen basal ganglia	BDNF-AS	0.22	0.17	lasso	4	0.13	5.5e-04	-6.58	7.6	2.2e-14	0.33	0.23	0.07	TRUE
8	ROSMAP	Brain Pre-frontal Cortex	METTL15	0.04	0.03	blup	364	0.03	4.6e-05	-3.25	-5.3	8.9e-08	-0.19	0.72	0.01	TRUE
7	NTR	Blood	LIN7C	0.01	0.00	lasso	3	0.01	2.2e-03	8.63	-8.3	7.0e-17	-0.74	0.10	0.80	FALSE
6	GTEx	Thyroid	LIN7C	0.08	0.04	lasso	4	0.04	6.0e-04	8.80	8.2	3.2e-16	0.71	0.39	0.52	FALSE
11	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	LIN7C	0.05	0.02	lasso	3	0.03	2.9e-04	9.11	7.9	2.5e-15	0.65	0.01	0.98	FALSE
5	GTEx	Liver	METTL15	0.18	0.05	lasso	3	0.09	1.9e-03	0.85	-7.1	1.1e-12	-0.69	0.02	0.83	FALSE
3	GTEx	Cells Transformed fibroblasts	LIN7C	0.26	0.22	lasso	6	0.25	1.4e-18	8.80	6.9	4.0e-12	0.64	0.98	0.02	FALSE
10	The Cancer Genome Atlas	Colon Adenocarcinoma	LIN7C	0.10	0.03	blup	32	0.08	2.8e-05	9.06	6.8	9.3e-12	0.56	0.01	0.95	FALSE
4	GTEx	Esophagus Muscularis	LIN7C	0.14	0.08	enet	11	0.07	5.4e-05	1.99	5.8	8.4e-09	0.62	0.66	0.20	FALSE
9	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	LIN7C	0.04	0.01	lasso	3	0.02	1.0e-02	-1.48	5.2	1.9e-07	0.48	0.02	0.81	FALSE