Best TWAS P=8.48e-11 · Best GWAS P=8.55e-12 conditioned to 0.603
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | SLC9A3R2 | 0.15 | 0.09 | enet | 7 | 0.10 | 7.8e-12 | -5.0 | 5.6 | 2.2e-08 | -0.58 | 0.18 | 0.82 | FALSE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | SLC9A3R2 | 0.16 | 0.11 | lasso | 6 | 0.12 | 6.3e-15 | -6.3 | 6.1 | 1.1e-09 | -0.61 | 0.06 | 0.94 | FALSE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | MLST8 | 0.22 | 0.18 | lasso | 6 | 0.18 | 7.1e-23 | 4.6 | 5.3 | 1.4e-07 | -0.47 | 1.00 | 0.00 | FALSE |
| 4 | YFS | Blood | MLST8 | 0.12 | 0.06 | bslmm | 326 | 0.06 | 4.3e-20 | -3.7 | 5.2 | 2.4e-07 | -0.37 | 1.00 | 0.00 | FALSE |
| 5 | The Cancer Genome Atlas | Brain Lower Grade Glioma | CASKIN1 | 0.02 | 0.00 | blup | 38 | 0.01 | 4.5e-02 | 4.1 | -5.9 | 2.9e-09 | 0.45 | 0.03 | 0.04 | TRUE |
| 6 | The Cancer Genome Atlas | Thyroid Carcinoma | CASKIN1 | 0.06 | 0.02 | blup | 38 | 0.04 | 1.5e-04 | -6.7 | -5.8 | 4.9e-09 | 0.80 | 0.00 | 0.97 | FALSE |
| 7 | The Cancer Genome Atlas | Thyroid Carcinoma | MLST8 | 0.09 | 0.07 | enet | 8 | 0.09 | 9.9e-09 | 5.0 | 5.1 | 2.8e-07 | -0.29 | 0.00 | 0.99 | FALSE |
| 8 | The Cancer Genome Atlas | Thyroid Carcinoma | SLC9A3R2 | 0.06 | 0.03 | lasso | 5 | 0.03 | 3.7e-04 | -5.0 | 6.5 | 8.5e-11 | -0.59 | 0.16 | 0.38 | TRUE |