TWAS hub - SLC9A3R2

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.152	0.0450	1.4e-04	0.092	0.037	0.097	0.092	0.094	3.0e-11	2.1e-05	7.8e-12	2.4e-11	1.7e-11
2	ROSMAP	Brain Pre-frontal Cortex	0.164	0.0381	1.2e-08	0.114	0.070	0.118	0.117	0.118	1.6e-14	2.3e-09	6.5e-15	9.1e-15	6.3e-15
3	TCGA	Thyroid Carcinoma	0.058	0.0260	1.1e-03	0.029	0.025	0.024	NA	0.032	7.5e-04	1.5e-03	1.8e-03	NA	3.7e-04

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Hand grip strength (right)	18.2	49.5	57.6	5.8	7.6	7.5
Hand grip strength (left)	16.1	42.5	50.6	5.2	7.0	7.1
Arm fat-free mass (left)	13.1	66.3	77.1	7.1	8.8	8.4
Arm predicted mass (right)	13.0	66.6	78.9	7.0	8.9	8.5
Arm predicted mass (left)	12.6	64.0	75.5	7.0	8.7	8.2
Arm fat-free mass (right)	12.3	63.2	74.5	6.9	8.6	8.2
Basal metabolic rate	10.9	60.6	70.7	6.8	8.4	8.0
Weight	10.2	50.2	56.2	6.4	7.3	7.5
Whole body fat-free mass	10.1	57.7	69.4	6.6	8.3	7.7
Leg fat mass (left)	10.1	39.4	44.6	5.8	6.3	6.7
Peak expiratory flow (PEF)	10.0	23.1	24.9	4.4	5.0	5.0
Systolic blood pressure, automated reading	9.9	28.9	33.0	5.7	5.4	4.9
Whole body water mass	9.9	56.5	68.2	6.5	8.3	7.7
Trunk fat-free mass	9.6	55.3	67.9	6.3	8.2	7.6
Leg fat mass (right)	9.5	36.8	42.1	5.6	6.1	6.5
Trunk predicted mass	9.3	53.2	65.1	6.2	8.1	7.5
Waist circumference	9.2	33.6	36.8	5.4	5.9	6.1
Heel T-Score	9.1	72.1	88.5	-7.3	-9.4	-8.7
Leg predicted mass (left)	8.9	47.1	55.4	6.1	7.4	7.0
Leg fat-free mass (left)	8.7	46.1	54.2	6.1	7.4	6.9
Whole body fat mass	8.7	36.3	41.9	5.6	6.0	6.5
Leg fat-free mass (right)	8.5	45.5	53.4	6.0	7.3	6.9
Leg predicted mass (right)	8.5	45.6	53.9	6.0	7.3	6.8
Diastolic blood pressure, automated reading	8.5	26.3	28.9	5.4	5.2	4.8
Hip circumference	8.3	35.8	39.8	5.8	5.8	6.3
Trunk fat mass	8.2	35.1	41.2	5.4	5.9	6.4
Systolic Blood Pressure	7.8	39.1	48.3	7.0	6.4	5.3
Wears glasses or contact lenses	7.8	9.0	13.0	-2.9	-3.6	-2.4
Arm fat mass (left)	7.1	29.1	31.6	5.3	5.2	5.6
Comparative height size at age 10	6.7	36.9	45.3	4.8	6.7	6.5
Sitting height	6.6	46.8	59.4	5.3	7.7	7.3
Fed-up feelings	6.3	11.5	13.5	3.5	3.7	3.0
Leg fat percentage (left)	6.3	23.0	27.0	4.6	4.6	5.2
Arm fat mass (right)	6.2	25.4	27.8	4.9	4.9	5.3
Blood White Count	5.9	43.6	47.3	6.1	6.8	6.9
Leg fat percentage (right)	5.8	21.1	25.0	4.4	4.4	5.0
Blood Red Count	5.7	55.1	58.4	7.6	7.6	7.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	5.7	6.8	8.5	2.5	2.3	2.9
BMI	5.6	32.8	34.6	5.6	5.7	5.9
Body mass index (BMI)	5.0	21.5	22.8	4.8	4.4	4.7
Eye problems/disorders: Glaucoma	5.0	5.9	9.3	-2.1	-3.1	-1.9
Trunk fat percentage	4.9	19.6	23.5	4.2	4.2	4.8
Hayfever, allergic rhinitis or eczema	4.9	10.6	15.2	-3.2	-3.9	-2.5
Impedance of arm (right)	4.9	22.9	27.1	-4.6	-5.2	-4.5
Body fat percentage	4.9	19.4	23.3	4.2	4.1	4.8
Allergy or Eczema	4.6	12.1	15.9	-3.6	-4.0	-2.8
Impedance of arm (left)	4.6	21.1	25.7	-4.2	-5.1	-4.4
Number of children fathered	4.5	5.1	5.3	-2.2	-2.2	-2.3
Forced expiratory volume in 1-second (FEV1)	4.4	14.7	17.4	3.2	4.2	4.1
Forced expiratory volume in 1-second (FEV1), Best measure	4.4	13.9	16.5	3.1	4.0	4.1
Qualifications: CSEs or equivalent	4.3	5.7	6.5	2.4	2.5	2.2
Standing height	4.3	42.8	54.9	4.6	7.4	7.2
Heart disease (mother)	4.3	5.2	7.2	2.7	1.8	2.3
Height	4.1	78.7	98.0	6.9	9.5	9.9
Exposure to tobacco smoke at home	4.0	4.4	5.6	2.4	1.9	2.0
Diabetes (father)	3.9	4.8	6.9	2.6	2.3	1.5
Hayfever/allergic rhinitis (self-reported)	3.9	5.1	7.4	-2.1	-2.7	-1.9
Allergy	3.8	8.8	12.5	2.7	3.5	2.6
Mother’s age at death	3.6	4.5	5.0	-2.1	-2.0	-2.2
Forced vital capacity (FVC)	3.4	13.0	18.3	2.8	4.3	3.6
Blood clot in the leg (DVT)	3.4	4.5	5.4	-2.1	-2.3	-1.8
Deep venous thrombosis (DVT) (self-reported)	3.4	4.4	5.5	-2.1	-2.4	-1.8
Heel bone mineral density (BMD) T-score, automated (left)	3.2	7.2	10.4	-2.0	-3.2	-2.7
Breastfed as a baby	3.2	4.0	4.4	-2.0	-1.9	-2.1
Medication: Co-codamol	3.1	3.6	7.1	2.7	1.1	1.6
Reason for reducing amount of alcohol drunk: Health precaution	3.1	3.6	5.5	-1.5	-1.8	-2.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	3.1	3.7	4.1	2.0	1.8	2.0
Ever unenthusiastic/disinterested for a whole week	3.0	3.7	4.1	2.0	1.9	1.9
Forced vital capacity (FVC), Best measure	3.0	11.0	14.7	2.5	3.8	3.4
Exposure to tobacco smoke outside home	3.0	4.1	6.2	1.8	2.5	1.6
Mineral and other dietary supplements	2.9	3.9	5.5	2.4	2.0	1.5
Average weekly champagne plus white wine intake	2.9	4.0	4.4	-2.1	-1.9	-2.0
Chronic bronchitis/emphysema (mother)	2.8	3.2	5.6	-1.2	-1.6	-2.4
Number of operations (self-reported)	2.8	4.2	6.2	-1.6	-1.9	-2.5
Crohns Disease (2017)	2.6	5.8	6.2	2.4	2.3	2.5
Mean Putamen Volume	2.6	3.0	5.2	1.6	1.2	2.3
Ever had bowel cancer screening	2.6	3.1	4.8	-1.4	-2.2	-1.6
Glaucoma (self-reported)	2.5	2.9	5.3	-1.4	-2.3	-1.3
Age at last live birth	2.5	3.6	3.9	-1.7	-2.0	-1.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	2.5	2.9	3.5	-1.6	-1.6	-1.9
Depressed Affect (Nagel 2018)	2.4	5.1	5.8	1.9	2.4	2.4
Ovarian Cancer	2.4	3.1	3.3	-1.7	-1.8	-1.8
Loud music exposure frequency	2.4	2.6	3.4	1.3	1.7	1.9
Ever had prostate specific antigen (PSA) test	2.4	2.8	3.8	-1.6	-2.0	-1.4
Ever depressed for a whole week	2.4	3.0	4.3	2.1	1.4	1.7
Bipolar Disorder (2018)	2.3	3.6	5.5	-2.3	-2.3	0.0
Illnesses of father: Heart disease	2.3	3.3	4.4	1.2	2.0	2.1
Alzheimer’s Disease (including proxy)	2.2	3.2	4.5	-1.5	-1.6	-2.1
Verbal and Numeric Reasoning (VNR)	2.2	5.3	6.6	2.1	2.6	2.2
Cardiovascular Disease	2.2	7.3	13.6	3.7	2.3	1.7
Alzheimer’s Disease (in mother)	2.1	2.5	3.2	-1.5	-1.4	-1.8
Heel bone mineral density (BMD) T-score, automated (right)	2.1	4.8	7.9	-1.6	-2.8	-2.0
Alcohol intake versus 10 years previously	2.1	3.2	4.5	1.3	2.1	1.8
Arm fat percentage (left)	2.1	8.4	9.9	3.1	2.4	3.1
Back pain experienced in last month	2.1	3.1	4.8	-1.4	-2.2	-1.6
Body Mass Index (BMI) (2010)	2.0	2.7	4.7	2.2	1.8	0.0
Number of live births	2.0	2.9	3.7	-1.9	-1.6	-1.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	2.0	4.1	5.6	2.1	1.6	2.4
Pain experienced in last month	2.0	3.3	4.7	1.6	1.6	2.2
Impedance of whole body	2.0	10.2	12.0	-3.3	-3.5	-2.8
Waist Hip Ratio (WHR)	1.9	8.3	14.3	2.0	3.8	2.6
Worrier / anxious feelings	1.9	3.6	5.6	-1.4	-1.8	-2.4
Alcohol intake frequency.	1.9	4.5	5.8	2.0	2.4	2.0
Family relationship satisfaction	1.9	2.3	2.5	-1.5	-1.6	-1.5
Qualifications: nursing, teaching	1.9	3.0	3.7	-1.9	-1.7	-1.5
Sensitivity / hurt feelings	1.8	3.1	5.7	-1.2	-1.6	-2.4
Severe depression (siblings)	1.8	2.0	2.5	-1.2	-1.4	-1.6
Taking other prescription medications	1.8	2.7	3.6	-1.0	-1.9	-1.9
Arm fat percentage (right)	1.8	7.0	8.1	2.8	2.2	2.8
Stomach or abdominal pain in last month	1.7	2.2	2.9	-1.5	-1.7	-1.1
Supplements: Vitamin C	1.7	2.0	2.6	-1.4	-1.6	-1.2
Alzheimer’s Disease (in father)	1.6	1.7	3.1	-0.8	-1.2	-1.8
Ever used hormone-replacement therapy (HRT)	1.6	2.0	2.7	-1.2	-1.4	-1.6
Supplements: Glucosamine	1.6	2.1	2.4	-1.5	-1.6	-1.3
Forced expiratory volume in 1-second (FEV1), predicted	1.6	3.3	4.7	1.2	2.0	2.2
Prospective memory result	1.5	1.8	2.3	-1.5	-0.9	-1.5
Gout (self-reported)	1.5	2.1	3.8	-1.1	-2.0	-1.1
Health satisfaction	1.5	1.9	2.6	-1.3	-1.6	-1.2
Number of full sisters	1.5	1.8	2.6	1.3	1.6	1.0
Type 2 Diabetes (T2D) (2018)	1.4	2.7	4.5	2.1	1.3	1.4
Lung FEV1/FVC ratio	1.4	7.0	10.7	2.4	2.2	3.3
Chronic bronchitis/emphysema (father)	1.4	1.7	2.2	-0.8	-1.5	-1.5
Medication: Allopurinol	1.4	1.9	3.2	-1.3	-1.8	-0.9
Medication: Omeprazole (e.g. Zanprol)	1.4	1.8	1.9	-1.4	-1.2	-1.4
Triglycerides	1.3	2.1	4.4	-1.4	-2.1	0.0
Chest pain or discomfort	1.3	1.9	2.8	1.7	1.4	1.0
Handedness (chirality/laterality): Left-handed	1.3	1.6	1.8	-1.3	-1.1	-1.3
Medication: Gliclazide	1.3	1.5	2.0	1.3	0.8	1.4
Hearing aid user	1.3	1.4	1.8	1.1	1.3	1.1
Vascular/heart problems diagnosed by doctor	1.3	3.6	7.2	-2.7	-1.7	-0.9
Age at First Birth	1.2	1.7	2.6	-1.6	-1.2	-1.0
Pack years adult smoking proportion	1.2	1.9	3.8	0.7	2.0	1.2
Medication: Lansoprazole	1.2	1.4	1.5	-1.2	-1.1	-1.2
Seen doctor (GP) for nerves, anxiety, tension or depression	1.2	1.8	3.0	1.7	0.9	1.3
High cholesterol (Self-reported)	1.2	2.1	3.1	-0.7	-1.7	-1.7
Supplements: Calcium	1.2	1.3	2.0	-1.4	-1.0	-0.9
Fasting Glucose	1.1	1.4	1.7	1.3	1.0	1.1
Neuroticism	1.1	2.6	3.8	2.0	1.6	1.1
Alcohol usually taken with meals	1.1	1.8	2.9	0.9	1.3	1.7
Medication: Paracetamol	1.1	1.7	2.3	-1.5	-1.4	-1.1
High blood pressure (siblings)	1.1	1.6	2.5	-0.8	-1.4	-1.6
Eye problems/disorders: None of the above	1.1	1.3	1.8	1.0	1.4	1.0
Medication: Seretide 50 evohaler	1.1	1.3	2.2	-0.8	-1.1	-1.5
Mean time to correctly identify matches	1.1	2.2	2.9	-1.4	-1.7	-1.3
Tinnitus: Yes, now most or all of the time	1.1	1.3	1.8	1.3	0.7	1.4
Prostate Cancer	1.0	1.4	1.9	-1.0	-1.2	-1.4
Vitamin and mineral supplements	1.0	1.4	2.2	1.5	1.3	0.6
Frequency of unenthusiasm / disinterest in last 2 weeks	1.0	1.4	2.2	1.3	0.6	1.5
Time employed in main current job	1.0	1.1	1.4	1.1	1.2	0.8
Noisy workplace	1.0	1.2	1.6	1.3	0.7	1.2
Tense / ‘highly strung’	1.0	1.6	2.0	-1.0	-1.4	-1.4
Pain type(s) experienced in last month: Hip pain	1.0	1.3	2.3	1.5	0.8	1.0
Supplements: Fish oil (including cod liver oil)	1.0	1.3	1.9	-1.4	-1.4	-0.5
Pack years of smoking	1.0	1.5	3.0	0.7	1.7	1.1
Coronary Artery Disease (CAD)	0.9	1.1	2.6	-1.6	-0.8	0.0
Relative age of first facial hair	0.9	1.9	3.2	-1.1	-1.1	-1.8
Pulse wave reflection index	0.9	1.1	1.5	1.0	0.8	1.2
Emphysema/chronic bronchitis	0.9	1.1	1.5	-0.6	-1.2	-1.1
Medication: Blood pressure	0.9	1.6	3.6	1.9	0.5	1.0
Knee pain experienced in last month	0.9	1.5	2.0	-1.1	-1.1	-1.4
Mood swings	0.9	1.7	2.2	1.3	1.5	1.0
Eye problems/disorders: Cataract	0.9	1.0	1.5	-1.0	-1.2	-0.8
Ever taken oral contraceptive pill	0.9	1.0	1.3	1.1	1.1	0.6
Basal cell carcinoma (self-reported)	0.9	1.1	1.3	1.0	1.2	1.0
Chronotype (morning person)	0.8	1.8	2.8	-1.7	-1.1	-1.2
Illnesses of mother	0.8	1.0	2.4	0.4	0.5	1.6
Birth weight	0.8	1.7	2.3	1.1	1.5	1.2
Medication for pain relief, constipation, heartburn	0.8	1.4	1.8	0.9	1.2	1.4
Had major operations	0.8	0.9	1.5	-0.4	-1.2	-1.1
Average weekly red wine intake	0.8	1.2	1.7	1.0	0.9	1.3
Miserableness	0.8	1.3	2.0	1.2	1.4	0.8
Medication: Lisinopril	0.8	1.0	2.2	1.5	0.8	0.6
Commuting to job workplace: Cycle	0.8	1.0	1.4	-1.2	-0.9	-0.9
Alcohol drinker status: Previous	0.8	0.9	1.4	1.2	0.9	0.8
Lupus	0.7	1.0	1.3	-1.1	-0.8	-1.1
Diverticular disease/diverticulitis (self-reported)	0.7	0.9	1.2	-1.0	-0.6	-1.1
Hair/balding pattern: Pattern 2	0.7	0.9	1.3	1.2	1.0	0.6
Had other major operations	0.7	0.8	1.1	-0.9	-0.7	-1.1
Birth weight of first child	0.7	1.3	2.3	1.1	1.5	0.8
Mouth/teeth dental problems: Bleeding gums	0.7	0.9	1.5	1.2	0.9	0.6
Medication: Omeprazole	0.7	0.8	1.0	-0.9	-1.0	-0.9
Loneliness, isolation	0.7	1.0	1.2	-0.9	-1.1	-1.0
Number of self-reported non-cancer illnesses	0.7	1.1	1.8	-0.3	-1.4	-1.2
Heart disease (siblings)	0.7	0.9	1.6	1.3	1.0	0.2
Intelligence (Savage-Jansen 2018)	0.6	1.8	3.1	1.8	1.2	0.9
Irritable Bowel Disease (IBD)	0.6	1.5	2.1	0.9	1.2	1.4
Reaction Time	0.6	1.2	1.4	-1.0	-1.1	-1.2
Crohns Disease (2012)	0.6	1.0	3.0	1.7	0.0	0.0
Medication: Metformin	0.6	0.8	1.3	1.2	0.8	0.6
Bilateral oophorectomy (both ovaries removed)	0.6	0.6	1.5	-0.3	-0.6	-1.2
High blood pressure	0.6	1.7	3.9	2.0	1.1	0.2
Financial difficulties in last 2 years	0.6	0.8	1.2	-1.0	-0.4	-1.1
Age at first live birth	0.6	1.0	1.4	-0.9	-1.2	-0.9
Leg pain on walking	0.6	0.8	1.2	-1.1	-0.8	-0.7
Long-standing illness, disability or infirmity	0.6	1.0	1.9	-0.2	-1.4	-1.0
Guilty feelings	0.6	0.9	1.7	1.3	0.4	0.9
Commuting to job workplace: Public transport	0.6	0.7	1.3	-0.4	-1.1	-0.8
Bipolar Disorder or Schizophrenia	0.5	1.2	3.7	-1.9	0.0	0.0
HDL Cholesterol	0.5	0.9	1.4	-1.1	-1.2	0.0
Angina	0.5	0.7	1.5	1.2	0.7	0.1
Medication for hormone replacement therapy	0.5	0.6	1.0	1.0	0.2	0.7
Medication: Atenolol	0.5	0.6	1.0	-1.0	-0.4	-0.8
Number of incorrect matches in round	0.5	0.9	1.5	-1.2	-0.9	-0.6
Frequency of tenseness / restlessness in last 2 weeks	0.5	0.7	1.5	-0.3	-1.2	-0.8
Fluid intelligence score	0.5	1.0	1.8	0.9	1.3	0.7
Qualifications: O levels/GCSEs or equivalent	0.5	0.7	1.4	0.5	1.2	0.7
Medication for cholesterol, blood pressure or diabetes	0.5	0.8	1.7	-1.3	0.3	-0.7
Qualifications: College or University degree	0.5	1.5	2.0	-1.3	-1.4	-0.9
Hypertension (Self-reported)	0.5	1.5	3.5	1.9	1.0	0.0
Friendships satisfaction	0.5	0.7	0.8	0.8	0.9	0.7
Illnesses of father: None of the above (group 1)	0.5	0.6	1.1	-1.1	-0.4	-0.6
Fractured/broken bones in last 5 years	0.5	0.6	1.0	-0.6	-0.7	-1.0
Blood Platelet Count	0.4	4.2	6.9	-1.6	-2.6	-1.8
Number of treatments/medications taken	0.4	0.7	1.5	0.1	-1.2	-0.7
Average weekly spirits intake	0.4	0.5	1.0	1.0	-0.4	0.6
Impedance of leg (right)	0.4	2.0	3.3	-1.8	-1.3	-1.0
Average weekly fortified wine intake	0.4	0.5	0.7	-0.7	-0.8	-0.6
Hearing difficulty/problems with background noise	0.4	0.6	1.2	-0.6	-0.5	-1.1
Pain all over the body in last month	0.4	0.4	0.6	0.7	0.3	0.8
Falls in the last year	0.4	0.6	1.0	1.0	0.6	0.6
Lung cancer (father)	0.4	0.4	0.6	-0.5	-0.7	-0.7
Medication: Amlodipine	0.4	0.5	0.8	0.8	0.3	0.9
Angina (self-reported)	0.4	0.5	1.1	1.0	0.6	-0.1
Illnesses of siblings: Diabetes	0.4	0.5	0.8	0.9	0.7	0.3
Ever had stillbirth, spontaneous miscarriage or termination	0.4	0.4	0.6	-0.8	-0.2	-0.7
Myopia	0.4	0.6	0.6	-0.8	-0.8	-0.7
Cholesterol lowering medication	0.4	0.6	1.1	0.2	-0.8	-1.1
Depression (Nagel 2018)	0.3	0.4	1.1	-0.4	0.0	1.1
Neuroticism (Nagel 2018)	0.3	0.7	0.8	0.8	0.9	0.7
Breast Cancer	0.3	0.6	1.0	0.3	1.0	0.9
Frequency of depressed mood in last 2 weeks	0.3	0.4	0.8	0.1	0.5	0.9
Impedance of leg (left)	0.3	1.4	2.5	-1.6	-1.1	-0.7
Past tobacco smoking	0.3	0.6	0.9	0.7	0.6	1.0
Qualifications: None of the above	0.3	0.7	1.1	1.1	0.5	0.8
Medication: Simvastatin	0.3	0.4	1.1	0.2	-1.1	-0.2
Father’s age at death	0.3	0.4	0.5	-0.4	-0.7	-0.7
Medication: Cholesterol lowering	0.3	0.5	1.1	-0.2	-1.0	-0.7
Pulse wave Arterial Stiffness index	0.3	0.3	0.7	0.8	0.4	0.3
Hair/balding pattern: Pattern 4	0.3	0.7	0.9	0.7	1.0	0.7
Comparative body size at age 10	0.3	0.7	2.0	-1.4	-0.3	-0.2
Mouth/teeth dental problems: Loose teeth	0.3	0.4	0.6	0.6	0.8	0.4
Overall health rating	0.3	0.6	1.5	1.2	0.1	0.5
Medication: Aspirin	0.3	0.4	0.8	-0.2	-0.9	-0.6
Medication for cholesterol	0.3	0.5	1.0	-1.0	0.4	0.5
Medication: Blood pressure	0.3	0.7	1.6	1.3	-0.0	-0.6
Medication: Atorvastatin	0.3	0.4	0.9	-0.2	-0.5	-0.9
Ever smoked	0.3	0.5	0.8	-0.7	-0.6	-0.9
Age started oral contraceptive pill	0.3	0.3	0.5	-0.6	-0.7	0.3
Ulcerative Colitis (UC)	0.2	0.5	1.0	-1.0	-0.4	-0.5
Neuroticism (2016)	0.2	0.3	0.6	0.0	-0.6	-0.8
Smoking Status	0.2	0.5	0.8	-0.8	-0.1	-0.9
Hypothyroidism (self reported)	0.2	0.4	0.5	-0.7	-0.6	-0.7
Maternal smoking around birth	0.2	0.3	0.6	0.8	0.3	0.4
Tinnitus: Yes, but not now, but have in the past	0.2	0.2	0.4	0.3	-0.3	-0.6
Multivitamins +/- minerals	0.2	0.3	0.5	-0.4	-0.5	0.7
Medication: Ramipril	0.2	0.2	0.4	0.4	-0.3	-0.6
Illnesses of siblings	0.2	0.3	0.7	-0.3	0.3	0.8
Hair/balding pattern: Pattern 3	0.2	0.3	0.5	-0.7	-0.5	-0.4
Pulse rate	0.2	0.3	0.3	-0.6	-0.5	-0.4
Qualifications: A levels/AS levels or equivalent	0.2	0.3	0.7	-0.6	0.0	-0.8
Depression (self-reported)	0.2	0.3	0.7	-0.3	-0.9	-0.0
Length of working week for main job	0.2	0.3	0.6	-0.2	-0.8	-0.4
Medication: Ventolin 100micrograms inhaler	0.2	0.2	0.4	0.6	0.4	-0.2
Seen a psychiatrist for nerves, anxiety, tension or depression	0.2	0.3	0.7	-0.0	-0.8	-0.4
Migraine (self-reported)	0.2	0.2	0.6	-0.8	-0.1	0.1
Suffer from ‘nerves’	0.2	0.2	0.5	0.7	0.3	0.4
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.2	0.2	-0.4	-0.5	-0.5
Smoking status: Previous	0.2	0.3	0.5	-0.6	-0.5	-0.7
Commuting to job workplace: Walk	0.2	0.2	0.4	-0.1	-0.3	-0.6
Mouth/teeth dental problems: Mouth ulcers	0.2	0.4	0.8	0.9	0.4	0.3
Alcohol drinker status: Never	0.2	0.2	0.5	-0.7	0.1	-0.3
Average weekly beer plus cider intake	0.2	0.3	0.9	-0.0	0.1	-0.9
Irritability	0.2	0.3	0.5	0.7	0.0	0.6
Risk taking	0.2	0.3	0.6	0.5	0.3	-0.7
Schizophrenia (2018)	0.1	0.1	0.3	-0.6	0.0	0.0
Worry (Nagel 2018)	0.1	0.1	0.4	0.2	-0.1	-0.6
HbA1C	0.1	0.1	0.2	0.4	0.2	-0.2
LDL Cholesterol	0.1	0.2	0.5	0.3	-0.7	0.0
Primary Biliary Cirrhosis	0.1	0.1	0.2	-0.3	-0.4	-0.2
Rheumatoid Arthritis	0.1	0.1	0.4	-0.6	0.0	0.0
Schizophrenia (2014)	0.1	0.2	0.6	0.8	0.0	0.0
Blood Eosinophil Count	0.1	0.8	1.7	-1.3	-0.8	-0.2
Respiratory disease	0.1	0.2	0.4	0.1	-0.6	-0.5
Hearing difficulty/problems: Yes	0.1	0.1	0.2	0.2	0.2	-0.4
Other serious medical condition/disability diagnosed by doctor	0.1	0.2	0.3	-0.5	-0.5	-0.1
Ever had hysterectomy (womb removed)	0.1	0.1	0.3	0.6	0.2	-0.0
Supplements: Zinc	0.1	0.1	0.1	-0.4	-0.3	-0.3
Townsend deprivation index at recruitment	0.1	0.2	0.3	0.4	-0.6	-0.3
Current tobacco smoking	0.1	0.2	0.5	0.2	0.7	-0.0
Age when periods started (menarche)	0.1	0.4	0.5	-0.4	-0.7	-0.7
Serious illness, injury or assault to yourself	0.1	0.2	0.4	-0.7	0.0	-0.3
Medication: Levothyroxine sodium	0.1	0.2	0.3	0.3	0.2	0.6
High blood pressure (mother)	0.1	0.2	0.4	0.2	-0.3	-0.6
Nervous feelings	0.1	0.2	0.5	0.7	0.2	0.2
Had menopause	0.1	0.1	0.3	-0.1	-0.5	0.0
Mouth/teeth dental problems	0.1	0.1	0.3	-0.5	0.1	-0.0
Heart attack	0.1	0.1	0.2	0.4	0.2	-0.1
Diabetes (self-reported)	0.1	0.1	0.1	0.3	-0.3	-0.3
Neuroticism score	0.1	0.2	0.5	0.7	0.4	0.0
Frequency of tiredness / lethargy in last 2 weeks	0.1	0.2	0.4	-0.1	-0.6	-0.3
Serious illness, injury or assault of a close relative in last 2 years	0.1	0.1	0.4	-0.6	-0.1	-0.3
Mouth/teeth dental problems: Dentures	0.1	0.1	0.3	0.2	-0.5	-0.0
Asthma	0.1	0.1	0.3	0.5	-0.2	-0.3
Medication: Ibuprofen (e.g. Nurofen)	0.1	0.1	0.2	-0.4	-0.1	-0.1
Ever highly irritable/argumentative for 2 days	0.1	0.1	0.3	-0.5	-0.3	-0.1
Hypothyroidism/myxoedema (self-reported)	0.1	0.1	0.2	-0.3	-0.4	-0.4
Number of full brothers	0.1	0.2	0.3	0.6	0.1	-0.5
Worry too long after embarrassment	0.1	0.1	0.3	0.6	0.2	0.1
Wheeze or whistling in the chest in last year	0.1	0.1	0.3	0.5	0.2	-0.3
Pulse wave peak to peak time	0.1	0.2	0.5	-0.7	-0.2	-0.2
Shortness of breath walking on level ground	0.1	0.1	0.3	-0.1	-0.1	-0.5
Neck or shoulder pain in last month	0.1	0.1	0.1	0.3	-0.3	0.1
Medication: Ibuprofen	0.1	0.1	0.3	-0.5	-0.2	-0.3
Pulse rate, automated reading	0.1	0.5	0.8	-0.7	-0.4	-0.9
Commuting to job workplace: Car/motor vehicle	0.1	0.1	0.2	-0.0	-0.2	-0.4
Illness, injury, bereavement, stress in last 2 years	0.1	0.1	0.3	0.6	-0.2	0.2
Diabetes diagnosed by doctor	0.1	0.2	0.6	0.8	0.2	0.1
Asthma (self-reported)	0.1	0.2	0.3	0.5	-0.2	-0.4
Osteoporosis (self-reported)	0.1	0.1	0.2	-0.3	0.0	-0.4
Smoking status: Current	0.1	0.2	0.6	0.2	0.8	-0.0
Medication: Bendroflumethiazide	0.1	0.1	0.2	0.4	0.1	-0.3
Medication: Paracetamol	0.1	0.2	0.4	-0.6	-0.4	-0.0
Unable to work because of sickness or disability	0.1	0.1	0.1	0.2	-0.3	-0.3
Schizophrenia vs Biploar Disorder	0.0	0.0	0.0	0.0	0.0	0.0
Major Depression (MDD)	0.0	0.0	0.0	0.0	0.0	0.0
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0
Type 2 Diabetes (T2D) (2012)	0.0	0.0	0.0	0.0	0.0	0.0
Ulcerative Colitis	0.0	0.0	0.1	-0.3	0.0	0.0
Lung FVC	0.0	0.1	0.2	0.4	0.4	-0.1
Hair Pigment	0.0	0.8	1.1	-1.1	-0.2	-1.1
Tanning	0.0	0.5	1.0	-0.5	-1.0	-0.4
Eye problems/disorders: Diabetes related eye disease	0.0	0.0	0.0	-0.1	-0.0	-0.2
Diabetes (mother)	0.0	0.0	0.0	0.1	-0.1	0.0
Relative age voice broke	0.0	0.0	0.0	0.1	0.1	0.1
Happiness	0.0	0.0	0.1	-0.3	0.1	-0.2
Headache pain in last month	0.0	0.0	0.1	-0.3	-0.1	-0.1
Breast cancer (self-reported)	0.0	0.0	0.1	0.2	-0.2	0.2
Osteoarthritis (self-reported)	0.0	0.0	0.1	0.1	-0.1	-0.2
Medication: Aspirin	0.0	0.1	0.1	0.2	-0.3	-0.1
Financial situation satisfaction	0.0	0.1	0.1	-0.2	-0.2	-0.3
Illnesses of father: High blood pressure	0.0	0.1	0.1	0.4	0.1	0.1
Heart attack/myocardial infarction (self-reported)	0.0	0.0	0.1	0.3	0.0	-0.2

Hub : Genes

SLC9A3R2

Models

Trait associations