TWAS hub - MLST8

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Artery Aorta	0.1400	0.0580	6.2e-03	-0.005	NA	0.002	NA	-0.004	9.8e-01	NA	2.4e-01	NA	6.0e-01
2	GTEx	Esophagus Mucosa	0.1480	0.0560	3.7e-03	-0.004	NA	0.015	NA	-0.003	8.6e-01	NA	3.2e-02	NA	6.5e-01
3	GTEx	Thyroid	0.1020	0.0370	1.6e-03	0.060	NA	0.054	NA	0.060	2.4e-05	NA	5.3e-05	NA	2.2e-05
4	ROSMAP	Brain Pre-frontal Cortex	0.2167	0.0435	5.6e-17	0.183	0.139	0.182	0.167	0.182	5.7e-23	2.1e-17	7.9e-23	7.1e-21	7.1e-23
5	YFS	Blood	0.1209	0.0266	6.7e-16	0.056	0.064	0.054	0.064	0.057	1.0e-17	4.4e-20	2.9e-17	4.3e-20	4.0e-18
6	TCGA	Bladder Urothelial Carcinoma	0.1870	0.0960	1.0e-03	-0.001	0.028	0.061	NA	0.002	4.6e-01	1.8e-03	7.3e-06	NA	2.1e-01
7	TCGA	Colon Adenocarcinoma	0.2680	0.0870	7.6e-06	0.086	0.084	0.082	NA	0.077	1.1e-05	1.4e-05	1.8e-05	NA	3.0e-05
8	TCGA	Glioblastoma Multiforme	0.1700	0.0970	9.2e-03	0.036	0.012	0.013	NA	0.002	3.0e-02	1.4e-01	1.3e-01	NA	2.7e-01
9	TCGA	Kidney Renal Clear Cell Carcinoma	0.0379	0.0228	3.5e-04	0.042	0.026	0.024	NA	0.035	1.5e-05	5.4e-04	8.1e-04	NA	7.6e-05
10	TCGA	Kidney Renal Papillary Cell Carcinoma	0.1080	0.0580	7.5e-05	0.079	0.071	0.107	NA	0.060	2.6e-05	6.8e-05	1.0e-06	NA	2.4e-04
11	TCGA	Brain Lower Grade Glioma	0.0689	0.0311	6.6e-09	0.072	0.081	0.083	NA	0.081	1.5e-08	1.8e-09	1.2e-09	NA	1.6e-09
12	TCGA	Liver Hepatocellular Carcinoma	0.1020	0.0540	1.4e-03	0.020	0.062	0.044	NA	0.025	3.9e-02	7.3e-04	3.9e-03	NA	2.3e-02
13	TCGA	Lung Squamous Cell Carcinoma	0.0647	0.0291	3.2e-06	0.031	0.061	0.062	NA	0.057	1.6e-04	1.8e-07	1.3e-07	NA	4.1e-07
14	TCGA	Pancreatic Adenocarcinoma	0.0910	0.0540	3.1e-03	0.047	0.040	0.036	NA	0.036	4.7e-03	8.7e-03	1.3e-02	NA	1.2e-02
15	TCGA	Prostate Adenocarcinoma	0.0998	0.0396	6.3e-08	0.042	0.066	0.086	NA	0.084	3.2e-05	2.0e-07	2.5e-09	NA	3.8e-09
16	TCGA	Skin Cutaneous Melanoma	0.1900	0.0880	3.0e-03	0.056	0.085	0.060	NA	0.090	1.3e-02	2.7e-03	1.0e-02	NA	2.1e-03
17	TCGA	Thyroid Carcinoma	0.0860	0.0380	1.8e-06	0.069	0.071	0.086	NA	0.078	3.0e-07	2.1e-07	9.9e-09	NA	5.3e-08

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17
Arm fat-free mass (right)	9.8	50.2	112.4	2.5	-3.6	8.2	9.6	10.6	2.9	-4.9	6.5	8.6	7.6	9.6	8.7	3.2	8.2	4.9	1.1	9.3
Trunk fat-free mass	9.7	55.5	116.6	2.6	-2.9	8.7	9.9	10.8	3.4	-5.1	7.7	9.0	7.8	10.0	8.8	3.8	9.1	5.5	1.4	9.7
Trunk predicted mass	9.6	55.1	114.5	2.7	-2.9	8.7	9.8	10.7	3.4	-5.1	7.7	9.0	7.8	10.0	8.7	3.8	9.1	5.5	1.5	9.6
Whole body fat-free mass	9.4	53.6	114.5	2.9	-2.6	8.6	9.7	10.7	3.4	-4.5	7.5	8.8	7.7	9.9	8.4	4.0	8.9	5.5	1.6	9.6
Whole body water mass	9.4	53.5	114.5	2.9	-2.6	8.6	9.7	10.7	3.3	-4.6	7.5	8.8	7.7	9.9	8.4	4.0	8.9	5.5	1.6	9.5
Arm fat-free mass (left)	9.4	47.8	108.2	2.1	-3.4	7.9	9.5	10.4	2.9	-5.1	6.3	8.3	7.4	9.3	8.3	3.0	8.0	4.5	0.8	9.3
Arm predicted mass (left)	9.4	47.7	108.2	2.4	-3.4	8.0	9.5	10.4	2.8	-5.0	6.5	8.4	7.3	9.3	8.3	3.0	8.1	4.6	0.9	9.1
Arm predicted mass (right)	9.3	47.7	108.2	2.1	-3.9	7.9	9.6	10.4	2.4	-5.3	6.3	8.3	7.4	9.3	8.6	2.8	7.8	4.5	0.7	9.0
Basal metabolic rate	9.0	49.8	108.2	2.6	-2.5	8.2	9.6	10.4	3.4	-4.5	7.1	8.5	7.5	9.6	8.1	3.6	8.5	5.0	1.1	9.4
Comparative height size at age 10	8.5	47.0	99.2	0.1	-1.6	7.5	10.0	9.7	1.3	-6.6	8.4	7.8	6.9	9.6	8.0	2.2	7.9	4.0	-0.6	9.1
Leg fat-free mass (right)	7.8	41.7	89.1	3.0	-1.8	7.6	8.4	9.4	3.3	-3.1	6.8	7.7	6.8	8.7	6.9	4.2	8.0	5.1	1.7	8.4
Leg predicted mass (right)	7.6	40.7	87.4	3.0	-1.7	7.5	8.3	9.3	3.2	-3.0	6.8	7.6	6.7	8.6	6.8	4.2	7.9	5.1	1.8	8.3
Leg predicted mass (left)	7.5	39.7	85.6	2.9	-1.9	7.4	8.3	9.2	3.2	-3.0	6.8	7.6	6.5	8.5	6.8	3.9	7.7	5.0	1.6	8.2
Leg fat-free mass (left)	7.4	39.1	84.1	2.8	-1.9	7.3	8.2	9.2	3.2	-3.0	6.8	7.5	6.5	8.4	6.7	3.9	7.7	4.9	1.6	8.2
Height	6.7	129.3	282.2	1.0	-2.8	13.1	16.8	15.6	3.0	-11.3	10.6	13.9	13.3	15.8	14.0	3.9	12.9	6.2	-0.2	14.4
Weight	6.6	32.7	74.0	1.6	-1.7	6.4	8.3	8.6	3.0	-4.1	5.4	6.9	6.1	8.0	6.4	2.1	6.5	3.1	-0.2	8.1
Standing height	6.3	62.5	136.9	-0.5	-3.8	8.6	11.7	10.7	1.7	-8.9	8.2	9.0	8.6	11.0	9.8	2.0	8.8	3.9	-0.9	10.1
Hip circumference	5.2	22.4	47.2	1.8	-1.2	5.4	6.6	6.9	2.8	-2.8	4.0	5.9	5.3	6.5	5.3	2.2	5.7	3.0	0.5	6.7
Forced expiratory volume in 1-second (FEV1), predicted	5.2	10.7	22.8	-0.6	-1.9	3.5	4.8	4.0	1.1	-3.0	3.8	3.5	3.5	4.6	4.4	1.1	3.7	1.6	-0.7	4.6
Sitting height	5.1	36.5	85.4	-2.1	-4.0	6.2	9.2	8.1	-0.7	-7.9	5.2	6.2	6.5	8.1	8.8	0.8	6.0	2.5	-1.5	7.3
Number of live births	4.4	6.3	11.0	-1.3	-0.7	-3.3	-2.3	-3.2	-2.0	-1.0	-2.2	-3.1	-2.6	-2.8	-2.2	-3.0	-3.0	-3.0	-2.2	-2.5
Medication: Atenolol	4.3	5.4	10.6	0.7	-0.4	3.0	2.8	2.6	1.5	-0.2	1.5	3.3	3.0	3.1	2.7	2.5	2.8	1.8	0.8	3.1
Hand grip strength (left)	4.1	10.9	30.4	-1.6	-3.1	2.8	5.5	4.4	-0.9	-4.7	1.8	2.9	3.2	4.3	4.6	-0.8	2.5	0.2	-2.1	4.4
Smoking status: Previous	4.0	6.0	16.4	1.5	-0.9	3.1	2.3	2.9	-0.5	-0.7	2.3	3.1	3.0	3.1	4.0	1.5	3.0	2.3	0.9	2.8
Past tobacco smoking	3.7	6.8	17.6	-1.5	0.1	-3.4	-2.7	-2.8	-0.0	1.0	-2.0	-3.5	-3.4	-3.5	-4.2	-1.4	-3.1	-2.3	-1.0	-3.2
Impedance of whole body	3.7	18.6	33.2	-4.7	0.4	-5.3	-3.6	-5.8	-3.2	-1.2	-4.4	-5.1	-3.7	-4.8	-4.0	-4.4	-5.5	-5.0	-3.5	-4.7
Commuting to job workplace: Car/motor vehicle	3.6	4.1	9.2	-0.8	0.9	-2.3	-2.2	-2.8	0.0	1.2	-1.9	-2.4	-2.7	-2.8	-3.0	-0.8	-2.5	-1.8	-0.7	-2.1
Medication: Bendroflumethiazide	3.6	5.4	8.1	2.4	1.7	2.6	1.2	2.8	2.2	2.1	1.5	2.6	2.2	2.0	1.9	2.8	2.7	2.9	2.8	2.1
Waist circumference	3.5	12.7	34.2	0.5	-0.6	3.5	5.8	5.6	2.5	-3.0	3.0	3.9	3.6	5.1	3.4	0.3	3.5	1.1	-1.4	5.7
Ever unenthusiastic/disinterested for a whole week	3.3	4.0	11.7	0.4	-0.5	2.4	3.0	3.4	-0.0	-2.0	1.8	2.1	2.2	2.6	2.1	1.4	2.1	0.8	-0.8	2.4
Impedance of arm (right)	3.3	15.5	35.5	-3.3	2.7	-4.8	-4.4	-6.0	-1.6	0.7	-2.6	-4.8	-4.2	-4.8	-5.0	-2.7	-4.5	-3.5	-1.8	-5.0
Medication for cholesterol, blood pressure or diabetes	3.3	5.4	12.1	-2.3	-1.5	-3.1	-2.1	-2.7	-0.8	-1.3	-2.3	-3.5	-2.1	-2.5	-2.7	-2.8	-2.5	-2.2	-1.9	-1.8
Whole body fat mass	3.3	13.7	37.3	0.4	-1.1	3.6	6.1	5.6	2.0	-3.4	2.8	4.3	4.1	5.3	4.0	0.2	3.4	0.7	-1.8	5.8
Trunk fat mass	3.2	13.8	39.7	-0.1	-1.4	3.5	6.3	5.5	1.7	-3.9	2.8	4.1	4.0	5.3	4.2	-0.1	3.2	0.4	-2.1	5.6
Noisy workplace	3.2	3.9	9.1	1.0	-0.1	2.3	2.1	2.5	-0.2	-0.3	0.9	2.7	2.9	2.5	3.0	1.7	2.3	1.7	0.8	2.4
Hand grip strength (right)	3.1	8.4	19.4	-2.2	-4.3	1.8	4.4	3.6	-1.1	-4.3	0.3	2.1	3.1	3.4	4.1	-1.4	1.5	-0.1	-2.1	3.6
Supplements: Glucosamine	3.1	4.0	8.8	-1.2	-0.3	-2.2	-2.3	-2.5	-2.0	0.3	-1.2	-2.3	-3.0	-2.4	-2.6	-2.3	-2.6	-1.1	-1.3	-1.9
Impedance of arm (left)	3.1	14.6	35.0	-3.3	2.2	-4.8	-4.3	-5.9	-1.8	0.7	-2.8	-4.7	-3.8	-4.6	-4.5	-2.7	-4.5	-3.5	-1.8	-4.7
Ever smoked	3.1	5.4	11.7	1.6	0.0	3.1	2.7	2.5	-0.3	-1.3	1.5	3.2	3.0	3.1	3.4	1.3	2.6	1.7	0.4	3.0
Leg fat mass (left)	3.1	12.3	30.7	0.7	-1.6	3.5	5.5	5.5	1.9	-2.7	2.2	4.2	3.9	5.0	4.0	0.2	3.3	1.1	-1.2	5.4
Osteoporosis (self-reported)	3.0	3.7	11.0	-0.9	1.6	-2.5	-1.9	-2.1	-0.6	-0.2	-1.3	-2.8	-2.0	-2.3	-3.3	-1.4	-2.1	-1.8	-1.3	-2.0
Falls in the last year	2.9	3.9	6.2	2.2	1.6	2.1	2.4	2.0	2.3	-0.4	2.2	1.8	2.5	2.5	2.1	1.2	2.3	1.4	0.7	2.2
Seen a psychiatrist for nerves, anxiety, tension or depression	2.9	3.8	7.7	1.5	1.3	2.5	1.6	1.9	1.0	0.4	1.7	2.1	2.2	2.3	2.3	2.4	2.8	2.1	1.6	2.1
Medication: Seretide 50 evohaler	2.8	3.2	9.2	-0.5	3.0	-1.9	-2.4	-2.3	0.7	1.9	-0.1	-1.8	-2.5	-2.1	-2.7	-0.2	-1.2	-0.4	0.6	-1.8
Leg fat mass (right)	2.8	10.8	27.7	0.7	-1.6	3.3	5.3	5.2	1.5	-2.7	2.1	4.0	3.5	4.7	3.8	-0.1	2.9	0.9	-1.3	5.1
Smoking Status	2.7	6.4	14.3	2.1	0.1	3.0	2.5	2.6	0.9	-0.5	1.5	3.3	3.5	3.2	3.8	1.6	3.2	2.5	1.4	3.1
Average weekly spirits intake	2.7	3.4	8.7	1.8	-0.3	2.7	1.9	2.1	1.5	-0.2	1.1	3.0	2.4	2.4	1.5	1.2	1.9	1.7	1.3	1.9
Impedance of leg (right)	2.7	13.2	22.9	-4.6	-1.2	-4.2	-2.0	-4.1	-3.2	-2.6	-3.8	-3.8	-2.7	-3.4	-2.1	-4.8	-4.6	-4.7	-3.9	-3.3
Medication: Cholesterol lowering	2.6	4.0	7.4	2.4	1.3	2.5	1.7	1.8	1.7	1.2	2.4	2.7	1.7	2.2	1.9	1.9	2.3	1.9	1.6	1.8
Arm fat mass (left)	2.6	10.5	26.4	1.3	-0.4	3.4	5.0	4.9	2.4	-2.1	2.6	4.0	3.5	4.5	3.2	0.8	3.5	1.2	-0.8	5.1
Neuroticism (2016)	2.5	3.6	8.2	2.3	1.7	2.1	1.5	2.5	0.8	0.8	2.9	1.8	1.6	2.0	1.3	2.5	2.3	1.7	1.6	1.2
Heel T-Score	2.5	19.5	64.0	4.2	4.6	-2.4	-6.8	-6.0	0.0	8.0	-2.6	-2.8	-3.4	-5.1	-4.0	3.2	-2.0	1.7	4.7	-5.7
Hypothyroidism (self reported)	2.5	5.7	20.9	4.6	-1.4	2.0	0.7	2.3	2.5	1.2	3.1	1.9	1.4	2.0	1.0	2.6	3.4	3.0	2.2	2.3
Impedance of leg (left)	2.5	12.1	23.0	-4.6	-1.2	-4.0	-1.5	-3.6	-3.0	-3.1	-4.1	-3.6	-2.0	-3.0	-1.7	-4.6	-4.3	-4.8	-4.1	-2.7
Had menopause	2.5	3.2	16.0	-1.7	0.4	-1.5	-0.3	-0.9	-4.0	-2.1	-1.1	-1.8	-1.1	-1.2	-0.6	-2.2	-2.0	-1.9	-2.1	-1.8
Commuting to job workplace: Walk	2.5	2.7	6.2	1.7	1.3	1.7	0.7	1.7	0.8	1.1	2.3	1.5	1.3	1.5	1.3	1.9	2.5	2.2	1.8	1.6
Commuting to job workplace: Public transport	2.5	3.0	7.5	1.1	0.6	2.1	1.3	2.0	0.9	0.8	2.7	1.7	1.3	2.2	0.6	1.9	2.5	2.2	0.8	2.3
Medication: Atorvastatin	2.5	3.1	5.8	-1.3	0.3	-2.4	-2.1	-1.5	0.6	1.0	-1.6	-2.4	-2.1	-2.3	-2.1	-1.6	-2.3	-1.5	-0.3	-1.8
Arm fat mass (right)	2.4	10.0	24.7	1.2	0.0	3.3	4.8	4.8	2.6	-1.9	2.8	3.9	3.2	4.4	2.9	1.0	3.5	1.4	-0.5	5.0
Shortness of breath walking on level ground	2.4	2.9	6.8	1.8	1.3	2.1	1.4	2.3	-0.1	1.1	1.8	1.5	1.7	1.7	2.1	2.6	2.0	1.8	1.2	1.0
Irritability	2.4	4.1	6.9	1.3	0.5	2.5	2.3	2.3	2.6	0.6	1.7	2.4	2.5	2.6	1.9	2.2	2.2	1.4	0.8	2.5
Heart disease (siblings)	2.4	2.9	6.4	0.3	-0.2	2.3	1.6	2.5	1.1	0.2	1.1	2.5	2.3	2.2	2.2	1.3	1.9	1.3	0.7	2.1
Heel bone mineral density (BMD) T-score, automated (left)	2.3	5.1	11.1	1.5	1.5	-2.0	-3.3	-3.3	-1.6	2.9	-3.0	-1.9	-2.0	-3.1	-1.9	-0.1	-2.2	0.2	1.1	-2.9
Had major operations	2.3	2.6	5.7	2.1	1.7	2.4	1.7	1.4	0.4	0.9	1.4	2.0	1.8	2.2	0.8	1.6	1.8	1.6	0.8	1.5
Qualifications: nursing, teaching	2.3	3.6	10.7	3.3	-1.7	1.6	-0.6	1.1	0.1	2.6	2.0	1.3	0.3	0.6	0.7	2.6	1.8	3.1	3.2	0.1
Triglycerides	2.2	3.6	12.4	3.1	2.0	1.4	-0.8	-0.4	2.4	2.1	1.8	1.4	0.7	0.3	0.2	2.7	2.1	2.4	3.5	-0.3
Cardiovascular Disease	2.2	7.2	19.4	3.9	0.7	2.4	0.1	3.2	2.3	4.4	1.4	2.0	1.4	1.1	0.8	4.3	2.7	3.5	4.2	0.9
Medication: Ventolin 100micrograms inhaler	2.2	2.8	6.9	-1.5	1.2	-2.0	-1.3	-2.3	0.4	0.4	-0.2	-2.1	-2.6	-2.0	-2.5	-1.1	-1.6	-1.6	-1.1	-1.8
Neuroticism (Nagel 2018)	2.1	4.8	11.2	3.3	0.0	2.5	1.8	2.7	0.4	0.6	2.0	2.0	2.8	2.5	2.2	3.3	2.6	2.2	1.6	1.7
Rheumatoid Arthritis	2.1	2.9	6.8	1.7	0.5	2.1	0.7	1.6	1.9	0.8	1.7	2.0	1.2	1.8	1.0	1.3	2.4	2.6	2.1	1.6
Eye problems/disorders: Diabetes related eye disease	2.1	2.3	5.8	-0.8	-1.3	-1.7	-1.2	-2.1	1.0	-1.3	-2.4	-1.2	-1.2	-1.6	-1.4	-1.6	-1.8	-2.0	-1.1	-0.9
Severe depression (siblings)	2.1	2.3	4.6	0.9	0.5	2.0	0.8	1.0	1.7	0.6	1.0	2.1	1.7	1.7	1.2	1.9	2.0	1.8	1.6	1.8
Hypothyroidism/myxoedema (self-reported)	2.1	4.0	16.5	4.1	-0.7	1.6	0.3	2.0	2.1	1.3	2.3	1.7	1.2	1.5	0.6	2.3	2.7	2.6	2.2	1.7
Mean Putamen Volume	2.0	2.3	4.3	-1.3	-1.8	-2.0	-1.1	-1.6	-1.1	-0.9	-0.3	-1.8	-2.1	-1.7	-0.9	-1.5	-1.9	-1.7	-1.4	-1.5
Relative age voice broke	2.0	3.0	7.5	-0.4	0.0	-2.1	-1.7	-2.3	0.3	-0.9	-2.7	-1.4	-1.3	-2.3	-1.9	-1.7	-2.1	-2.3	-1.1	-1.9
Medication: Simvastatin	2.0	3.0	5.4	2.1	1.5	2.0	1.2	1.6	2.3	1.2	1.7	2.3	1.6	1.6	1.0	2.0	1.9	1.3	1.6	1.6
Forced expiratory volume in 1-second (FEV1), Best measure	2.0	6.4	12.1	-0.7	-1.4	2.7	3.5	3.4	1.3	-2.9	3.0	2.9	2.6	3.5	2.5	0.9	3.1	1.3	-0.1	3.2
Birth weight	2.0	4.4	11.9	-0.1	2.8	2.5	2.2	3.1	1.5	-0.7	3.5	2.4	1.0	2.5	1.0	0.9	2.6	2.0	0.5	2.4
Medication: Blood pressure	2.0	3.6	9.6	1.7	0.9	2.5	1.6	2.5	0.1	1.3	1.5	2.6	1.5	1.6	2.3	3.1	2.0	1.8	1.7	1.3
Ulcerative Colitis	1.9	2.8	5.8	0.0	0.0	-2.1	-1.4	-2.0	-2.1	0.1	-2.2	-2.2	-1.6	-2.1	-0.9	-1.3	-2.4	-1.7	-1.3	-1.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.9	2.3	8.8	1.1	3.0	1.1	-0.5	-0.5	2.6	1.8	1.0	1.5	0.4	0.3	-0.8	2.1	1.2	1.3	2.1	-0.0
Long-standing illness, disability or infirmity	1.9	2.9	7.3	2.7	1.6	2.0	1.0	1.7	1.6	2.5	1.3	1.8	1.1	1.4	0.7	2.7	1.5	1.5	1.5	0.6
Ever depressed for a whole week	1.9	2.4	7.3	1.1	-0.4	1.8	1.7	2.7	-0.7	0.4	1.9	1.5	1.2	1.8	1.4	2.2	1.9	1.6	0.3	1.4
Depressed Affect (Nagel 2018)	1.8	3.7	8.0	2.4	-0.8	2.0	2.5	2.2	-0.1	-1.1	1.6	1.9	2.6	2.5	2.8	1.6	2.0	1.0	0.2	2.1
Medication: Ramipril	1.8	2.3	7.0	2.6	0.1	1.6	0.7	1.4	1.3	1.3	-0.2	1.9	1.9	1.2	1.6	1.7	1.4	1.6	2.0	0.9
Pack years of smoking	1.8	2.6	7.5	0.3	0.0	1.8	2.7	2.2	-0.8	-1.4	0.4	2.0	2.2	2.3	2.6	-0.4	0.8	0.3	-1.1	1.6
Gout (self-reported)	1.7	2.3	8.0	1.6	0.8	1.6	-0.5	0.4	1.4	1.0	1.6	1.8	0.9	0.8	0.6	1.9	2.1	2.4	2.8	-0.2
Hypertension (Self-reported)	1.7	4.6	13.1	3.3	1.0	1.9	-0.3	2.3	0.9	3.6	0.7	1.7	1.3	0.8	0.5	3.5	2.0	3.0	3.5	0.5
Unable to work because of sickness or disability	1.7	2.2	6.4	0.9	1.6	1.9	1.6	1.0	-0.0	-0.7	0.2	1.8	2.5	2.0	1.5	1.3	1.8	1.0	0.1	1.9
Worry (Nagel 2018)	1.6	3.3	12.5	2.8	-0.1	1.8	0.4	1.7	1.0	1.8	2.0	1.1	1.4	1.3	1.2	3.5	2.2	2.2	2.2	0.5
Maternal smoking around birth	1.6	2.3	7.8	0.5	1.9	1.8	1.2	1.2	2.8	0.6	0.6	2.1	1.9	1.6	0.4	1.4	1.7	1.0	1.3	1.4
High blood pressure	1.6	4.4	13.7	3.3	0.9	1.8	-0.4	2.0	0.6	3.7	0.7	1.6	1.3	0.8	0.5	3.3	2.0	3.0	3.5	0.3
Mother’s age at death	1.6	1.9	5.6	-0.8	-0.9	-1.5	-2.3	-2.4	-0.9	1.2	-0.3	-2.0	-1.3	-1.7	-1.8	0.7	-1.0	-0.0	1.0	-1.5
Medication: Blood pressure	1.6	3.0	7.5	2.1	2.2	1.3	-0.4	1.3	2.6	2.7	0.0	1.6	1.2	0.7	-0.5	1.9	1.7	2.1	2.7	1.0
Neuroticism	1.5	3.6	8.1	2.8	-0.5	1.9	1.5	2.8	0.1	0.5	2.6	1.4	1.7	1.9	1.9	2.9	2.3	1.8	1.3	1.1
Forced vital capacity (FVC), Best measure	1.5	5.6	11.0	-1.0	-0.6	2.4	3.3	3.3	0.9	-3.0	2.7	2.7	2.3	3.1	2.6	0.6	2.9	1.2	-0.2	3.0
Pain experienced in last month	1.5	2.5	5.1	-0.4	-0.1	1.6	2.3	2.0	0.3	-1.9	2.2	1.6	1.8	2.2	2.0	0.8	1.7	0.4	-0.2	1.7
Alzheimer’s Disease (in father)	1.4	1.5	5.2	0.6	1.4	1.2	-0.0	1.2	1.5	1.8	0.4	0.6	0.4	0.6	0.2	1.3	1.3	2.1	2.3	0.7
Ulcerative Colitis (UC)	1.4	2.7	7.3	-1.7	-2.0	-1.7	-0.7	-1.8	-1.7	-1.8	-2.7	-2.0	-0.5	-1.3	-0.6	-1.1	-1.7	-2.0	-1.9	-0.7
BMI	1.4	8.1	21.3	2.3	-0.5	3.0	4.2	4.4	2.5	-0.6	2.3	3.3	2.9	4.0	2.3	1.3	3.1	1.5	-0.2	4.6
Chronotype (morning person)	1.4	3.2	8.4	-1.5	0.1	-2.2	-2.9	-1.8	-1.2	1.1	-0.4	-2.3	-2.5	-2.6	-1.9	-0.5	-1.5	-0.6	0.9	-2.7
Sensitivity / hurt feelings	1.4	2.3	6.4	2.5	1.9	1.3	0.1	1.5	1.6	1.1	1.5	0.9	0.6	0.7	-0.8	2.4	1.8	1.8	2.3	0.3
Chronic bronchitis/emphysema (father)	1.4	1.7	4.6	0.4	0.0	-1.7	-2.1	-1.1	-0.2	0.8	-1.2	-1.8	-1.9	-2.1	-1.4	-0.5	-1.2	-0.7	0.2	-1.4
Body mass index (BMI)	1.4	6.1	16.1	1.9	-0.2	2.7	3.4	4.0	2.5	-0.3	1.8	3.0	2.5	3.3	2.2	1.2	2.7	1.3	0.0	3.8
Forced vital capacity (FVC)	1.4	5.2	10.9	-0.6	-1.7	2.3	3.2	3.3	0.7	-2.7	2.5	2.4	2.2	2.9	2.7	1.0	2.8	1.5	0.3	2.7
Heel bone mineral density (BMD) T-score, automated (right)	1.4	3.1	8.8	1.0	0.1	-1.6	-2.9	-2.6	-1.4	2.2	-3.0	-1.3	-1.2	-2.3	-1.0	-0.1	-1.9	0.0	0.9	-2.2
Worrier / anxious feelings	1.4	2.6	11.1	2.6	-0.2	1.5	-0.1	1.4	-0.2	2.3	1.5	0.7	0.9	0.7	1.0	3.3	1.5	2.0	2.3	-0.1
Forced expiratory volume in 1-second (FEV1)	1.4	4.7	8.7	-0.4	-2.4	2.2	2.8	3.0	1.0	-2.3	2.4	2.4	2.1	2.8	2.2	1.1	2.8	1.5	0.6	2.6
Birth weight of first child	1.4	2.6	5.4	0.7	0.5	2.0	1.3	2.0	2.1	0.5	1.7	1.9	1.2	1.8	1.0	1.4	2.2	1.8	1.5	2.3
High blood pressure (siblings)	1.4	2.0	7.3	1.8	0.1	1.1	-1.3	0.2	1.0	2.7	1.1	1.2	-0.6	-0.1	0.0	1.7	1.1	2.3	2.6	0.0
Number of children fathered	1.4	1.6	5.9	0.1	0.4	-1.2	-1.6	-1.5	-1.5	2.4	-1.0	-1.4	-1.1	-1.5	-0.9	0.8	-1.6	-0.3	0.6	-1.6
Number of self-reported non-cancer illnesses	1.4	2.4	9.9	3.1	1.3	1.0	-0.9	0.5	2.0	2.8	1.0	1.1	-0.3	-0.1	-0.6	1.7	1.1	1.7	2.4	-0.5
Wears glasses or contact lenses	1.4	1.6	3.9	-1.1	0.5	-1.1	-1.3	-2.0	-1.5	0.3	-0.2	-1.0	-1.7	-1.2	-1.3	-1.6	-1.7	-1.1	-1.0	-1.4
Vascular/heart problems diagnosed by doctor	1.4	3.8	10.7	-2.9	-1.0	-1.9	-0.4	-2.4	-0.5	-3.3	-0.4	-1.8	-1.6	-1.1	-0.6	-3.0	-1.7	-2.5	-2.8	-0.6
Pack years adult smoking proportion	1.3	2.0	5.7	0.3	0.1	1.7	2.4	1.9	-0.4	-1.2	0.2	1.8	2.0	2.1	2.2	-0.3	0.9	0.4	-0.8	1.5
Nervous feelings	1.3	2.4	9.0	2.4	0.2	1.6	0.5	1.8	0.1	2.1	1.0	1.2	0.9	0.9	0.7	3.0	1.6	2.1	1.7	0.6
Pain all over the body in last month	1.3	1.4	3.5	0.5	-0.5	0.7	1.8	0.5	-0.2	-1.1	-1.7	0.9	1.7	1.1	1.0	0.2	-0.2	-1.3	-1.9	1.8
Father’s age at death	1.3	1.7	3.3	-0.4	0.5	-1.4	-1.0	-1.8	-1.1	0.2	-1.3	-1.2	-1.5	-1.7	-1.1	-1.7	-1.8	-1.4	-1.0	-1.6
Qualifications: O levels/GCSEs or equivalent	1.3	2.1	6.6	1.0	-0.7	-1.2	-2.5	-1.9	0.8	2.6	-1.5	-0.9	-1.3	-1.8	-2.0	0.3	-0.8	0.9	1.5	-0.7
Mood swings	1.3	2.3	5.3	2.3	-0.5	1.5	1.7	2.3	0.6	-0.5	1.5	1.1	1.6	1.6	2.2	1.5	1.6	0.9	0.4	1.7
Medication for cholesterol	1.3	2.0	8.3	-1.6	-2.1	-0.4	1.2	-1.1	-2.1	-2.9	-0.5	-0.5	0.3	0.4	0.8	-1.3	-0.9	-1.7	-2.4	-0.1
Average weekly champagne plus white wine intake	1.3	1.8	5.1	1.7	0.3	1.8	0.5	0.4	0.2	1.4	2.3	1.6	0.7	1.2	0.8	1.7	1.5	2.1	1.6	0.4
Fractured/broken bones in last 5 years	1.3	1.7	3.8	1.0	-1.1	1.4	1.8	0.9	0.8	-0.5	0.4	1.3	1.9	1.8	1.1	1.3	1.7	1.1	0.3	1.9
Medication: Levothyroxine sodium	1.2	2.1	8.6	2.9	-0.4	0.7	-0.1	1.0	2.2	1.7	1.2	0.9	0.6	0.8	-0.3	1.3	1.7	2.0	2.0	1.2
Heart attack	1.2	1.6	4.0	2.0	0.1	1.4	0.3	1.3	0.5	1.6	1.0	1.3	1.1	1.0	0.8	2.0	1.3	1.5	1.4	0.4
Ever had bowel cancer screening	1.2	1.4	3.8	0.3	-0.2	-1.3	-1.3	-1.6	-0.7	0.1	-1.3	-0.9	-1.5	-1.8	-0.8	-0.9	-1.5	-1.3	-0.7	-2.0
Back pain experienced in last month	1.2	1.7	4.7	-0.3	1.6	-1.0	-1.8	-2.2	-0.0	0.7	-2.1	-0.8	-0.9	-1.4	-1.6	-0.4	-1.6	-1.0	-0.1	-1.7
Age at First Birth	1.1	1.6	4.4	-0.2	-1.1	-1.5	-0.2	-1.6	-1.5	-1.3	-0.7	-1.3	-1.1	-1.0	-1.0	-1.0	-1.5	-1.9	-2.1	-0.8
LDL Cholesterol	1.1	1.7	5.6	1.6	1.2	1.4	0.7	0.8	2.4	0.5	1.3	1.6	1.1	1.4	0.1	0.8	1.6	1.5	1.6	1.0
Respiratory disease	1.1	2.5	9.5	1.3	1.2	-1.2	-1.7	-2.0	1.3	2.2	0.6	-1.3	-2.7	-1.8	-3.1	-0.0	-0.9	-0.2	0.5	-1.3
Diabetes (mother)	1.1	1.4	4.1	1.9	1.4	0.8	-0.7	0.1	1.8	1.1	1.5	0.8	-0.2	0.1	0.3	1.0	1.3	1.4	2.0	-0.1
Trunk fat percentage	1.1	4.6	16.2	-1.0	-0.5	1.1	4.0	2.9	0.8	-2.8	0.7	1.7	2.1	2.8	1.8	-1.2	0.8	-1.3	-2.9	3.4
Average weekly fortified wine intake	1.1	1.3	3.2	0.9	-0.2	-0.9	-1.8	-1.3	-0.0	1.2	-1.0	-1.0	-1.4	-1.4	-1.6	-0.9	-1.4	-0.1	0.5	-1.7
Fed-up feelings	1.1	2.0	4.3	1.7	0.4	1.4	1.7	2.1	0.8	0.2	1.4	1.1	1.7	1.6	1.7	2.0	1.6	1.1	0.8	1.3
Alcohol intake versus 10 years previously	1.1	1.6	6.5	-1.6	-0.1	0.8	1.6	1.2	0.8	-2.5	0.3	1.0	1.0	1.3	1.6	-0.6	0.8	-0.3	-1.2	2.0
Loud music exposure frequency	1.1	1.2	4.3	0.3	-2.1	0.9	1.3	1.6	-1.1	-0.4	-0.1	1.0	1.7	1.1	1.7	0.8	0.9	0.6	0.1	0.5
Mouth/teeth dental problems: Bleeding gums	1.1	1.4	5.1	0.8	-1.1	-0.7	-1.2	0.3	1.3	2.2	-0.2	-1.0	-1.4	-1.4	-2.0	1.2	-0.4	0.1	1.2	-1.3
Glaucoma (self-reported)	1.1	1.3	3.8	1.5	0.3	1.2	-0.3	0.0	1.1	1.7	0.8	1.4	0.5	0.6	0.5	1.5	1.4	1.7	2.0	0.2
Miserableness	1.1	1.9	5.2	2.3	-0.3	1.4	1.5	1.7	-0.0	0.4	1.7	0.8	1.4	1.5	1.5	2.0	1.7	1.4	0.8	1.1
Medication: Omeprazole (e.g. Zanprol)	1.1	1.3	7.1	0.8	2.5	0.1	-1.2	0.1	0.3	2.7	0.3	-0.0	-1.2	-0.7	-1.6	0.7	-0.2	0.7	0.7	-0.9
Blood White Count	1.0	7.4	23.3	-1.4	-1.1	1.6	4.8	3.6	0.9	-3.9	1.3	2.1	2.6	3.4	2.6	-1.5	1.4	-1.0	-3.4	4.5
Number of treatments/medications taken	1.0	1.8	8.4	2.9	1.1	0.7	-0.8	0.5	1.6	2.6	0.5	0.8	-0.1	-0.0	-0.3	1.8	0.9	1.5	1.8	0.4
Fluid intelligence score	1.0	2.0	4.7	-0.2	-1.3	-1.4	-1.1	-1.2	-2.2	0.8	-1.7	-1.6	-1.3	-1.6	-1.3	-1.4	-2.1	-0.9	-1.0	-1.8
Prospective memory result	1.0	1.3	4.4	1.0	0.7	0.7	-0.4	1.5	0.4	0.8	2.0	0.1	-0.4	0.3	0.2	1.4	1.4	1.8	2.1	-0.2
Illnesses of mother	1.0	1.3	3.1	-1.4	-0.6	-1.0	0.3	-0.4	-1.5	-1.4	-1.6	-0.9	-0.1	-0.5	-0.7	-1.5	-1.4	-1.5	-1.8	-0.5
Migraine (self-reported)	1.0	1.3	4.6	-0.4	-2.1	-0.9	-1.0	-0.0	-2.1	-0.5	-1.8	-0.4	-1.2	-1.1	0.5	-1.3	-1.1	-0.3	-0.4	-1.1
Asthma (self-reported)	1.0	1.9	7.6	1.3	1.9	-0.2	-0.8	-1.1	1.7	2.8	1.3	-0.5	-2.1	-0.8	-2.6	0.6	-0.3	0.5	0.6	-0.7
Number of operations (self-reported)	1.0	1.4	3.8	2.0	1.0	1.5	0.3	-0.4	0.6	1.5	0.8	1.5	1.0	1.2	0.2	1.5	1.2	1.6	1.2	1.1
Supplements: Calcium	1.0	1.1	3.9	-0.9	2.0	-0.6	0.6	-1.5	-0.7	-1.0	-0.8	-0.9	0.5	-0.1	-0.1	-1.2	-1.1	-1.5	-1.6	-0.1
Heart attack/myocardial infarction (self-reported)	1.0	1.2	3.5	1.9	0.1	1.2	-0.0	1.1	0.7	1.5	0.7	1.2	1.0	0.8	0.6	1.8	1.2	1.4	1.5	0.3
Ovarian Cancer	0.9	1.1	3.6	1.0	1.9	0.2	-0.5	-0.8	1.4	1.8	1.0	-0.2	0.2	0.1	-1.1	1.6	0.4	1.0	1.6	-0.4
Prostate Cancer	0.9	1.2	4.1	0.7	2.0	-0.5	-1.4	-1.3	1.2	1.4	-0.9	-0.4	-0.4	-0.9	-1.4	1.2	0.2	0.4	1.5	-0.7
Waist Hip Ratio (WHR)	0.9	4.2	18.4	-3.4	-0.1	-1.1	2.3	0.2	-0.5	-3.0	-0.4	-1.1	-0.6	0.3	-1.1	-3.1	-1.8	-2.9	-4.3	1.1
Medication: Metformin	0.9	1.3	3.1	-0.0	0.6	-1.3	-1.1	-0.8	1.6	0.4	-1.4	-1.3	-1.4	-1.4	-1.8	-0.9	-1.1	-0.8	0.1	-1.1
Multivitamins +/- minerals	0.9	1.1	4.9	0.4	-0.1	-1.2	-2.2	-0.7	0.3	1.4	-0.7	-0.8	-1.0	-1.4	-0.6	-0.6	-0.6	0.8	1.6	-1.2
Stomach or abdominal pain in last month	0.9	1.1	5.2	0.2	-0.6	-1.3	-1.7	-1.4	0.3	-0.2	-2.3	-1.1	-0.3	-1.3	0.0	-1.3	-1.1	-0.5	0.2	-0.9
Hair/balding pattern: Pattern 2	0.9	1.1	2.7	-0.6	0.7	1.4	1.5	1.2	0.8	-0.4	1.2	1.4	1.2	1.6	1.1	0.0	0.9	0.2	-0.1	1.2
Asthma	0.9	1.8	7.1	1.3	2.0	-0.0	-0.7	-1.0	1.9	2.7	1.4	-0.3	-2.0	-0.6	-2.4	0.5	-0.1	0.7	0.7	-0.5
Breastfed as a baby	0.9	1.1	3.1	-0.5	0.9	-0.9	-1.2	-1.8	-0.3	-0.1	-1.7	-0.6	-1.1	-1.3	-1.4	-0.7	-1.2	-0.9	-0.3	-0.9
Blood clot in the leg (DVT)	0.9	1.2	3.7	1.6	0.7	0.7	-0.5	-0.3	1.9	1.7	1.1	0.4	0.2	0.6	-1.2	0.6	1.0	1.4	1.6	0.5
Medication: Amlodipine	0.9	1.3	2.5	1.5	1.0	1.4	1.5	1.4	0.7	0.4	1.0	1.6	1.3	1.4	0.4	1.3	1.2	0.7	0.1	1.1
Body fat percentage	0.9	3.7	13.0	-0.7	-0.4	1.0	3.6	2.7	0.8	-2.2	0.4	1.6	1.8	2.5	1.6	-1.3	0.6	-1.2	-2.6	3.1
Health satisfaction	0.9	1.2	9.4	3.1	-0.3	0.2	-1.2	0.4	0.1	1.3	0.1	-0.0	-0.0	-0.5	0.0	2.0	0.5	0.7	1.4	-0.7
Eye problems/disorders: None of the above	0.9	1.1	3.3	-0.2	0.6	1.0	1.5	1.3	0.4	-1.1	1.8	0.5	1.0	1.3	1.6	-0.1	1.1	0.4	-0.1	1.3
Mean time to correctly identify matches	0.9	1.8	4.4	1.4	0.3	1.5	1.5	2.1	-0.5	0.1	1.9	1.4	1.6	1.9	1.4	1.4	1.2	0.8	-0.3	0.8
Medication: Aspirin	0.9	1.2	4.5	1.7	-0.7	0.8	-0.5	0.7	1.1	2.1	0.7	0.6	-0.0	0.1	0.4	1.7	0.5	1.2	1.9	-0.3
High cholesterol (Self-reported)	0.9	1.7	9.0	1.4	1.2	1.2	0.1	0.5	3.0	1.7	0.9	1.4	0.7	0.7	0.0	1.1	1.2	0.9	1.7	1.0
Leg fat percentage (left)	0.9	3.4	9.8	-0.4	-1.4	0.9	3.1	2.7	0.5	-1.9	-0.5	1.6	1.8	2.2	1.8	-1.6	0.4	-1.1	-2.5	3.0
Deep venous thrombosis (DVT) (self-reported)	0.9	1.2	3.4	1.5	1.3	0.8	-0.3	-0.3	1.8	1.4	1.4	0.6	0.1	0.7	-1.2	0.5	1.1	1.3	1.5	0.6
Crohns Disease (2017)	0.8	1.8	6.1	0.8	-0.9	1.3	1.2	2.2	0.5	-1.9	0.5	1.5	1.3	1.2	2.5	-0.0	1.3	0.9	-0.1	1.8
Lung FEV1/FVC ratio	0.8	4.1	9.6	0.7	-0.3	2.4	2.7	2.7	2.4	-1.0	2.5	2.3	2.4	3.1	0.7	0.7	2.1	1.1	0.3	2.8
Other serious medical condition/disability diagnosed by doctor	0.8	1.1	3.1	1.4	-0.3	1.1	1.4	1.3	0.2	0.2	0.9	1.3	1.2	1.4	0.9	0.9	0.8	0.3	-0.4	1.8
Angina	0.8	1.0	3.1	1.8	0.1	0.9	0.4	1.0	1.4	1.4	0.4	1.3	1.1	0.6	0.9	1.5	0.7	0.8	1.1	0.2
Medication for hormone replacement therapy	0.8	0.9	3.4	0.1	0.6	-1.0	-1.6	-0.3	-1.0	0.7	0.3	-1.1	-1.8	-1.4	-0.9	-0.8	-0.8	0.2	0.1	-1.3
Diabetes (father)	0.8	1.1	2.9	-0.7	1.7	-1.0	-0.4	0.1	-0.7	0.5	-0.6	-1.3	-1.3	-1.1	-1.5	-0.6	-1.2	-0.8	-0.4	-1.6
Taking other prescription medications	0.8	1.2	6.5	2.5	0.6	0.4	-1.1	0.3	1.1	2.0	0.1	0.3	-0.3	-0.2	-0.6	1.3	0.6	1.2	1.4	-0.1
High blood pressure (mother)	0.8	1.1	5.4	1.3	0.1	0.6	-1.0	0.3	0.7	1.0	1.1	0.4	0.2	0.1	0.2	1.5	1.3	1.6	2.3	-0.0
Allergy	0.8	1.7	4.8	-2.2	-1.8	-0.2	1.1	1.8	-1.0	-1.7	-1.7	0.1	1.4	0.4	2.0	-0.6	-0.4	-1.2	-1.1	0.8
Neuroticism score	0.8	1.7	6.9	2.4	-0.1	1.3	0.9	1.9	-0.3	0.6	1.7	0.5	1.0	1.0	0.8	2.6	1.5	1.2	0.9	0.4
Hair/balding pattern: Pattern 3	0.8	1.2	4.6	1.4	-0.8	1.2	0.2	2.1	-0.3	1.2	-0.3	0.9	0.9	0.3	1.8	1.4	0.6	1.2	1.2	0.1
Length of working week for main job	0.8	0.9	3.5	0.0	0.7	1.4	1.4	1.0	-0.4	-0.7	1.9	1.2	0.6	1.4	0.7	0.7	0.9	0.6	-0.0	0.8
Headache pain in last month	0.8	1.5	3.6	-0.1	-0.6	-1.4	-1.9	-1.6	0.5	0.4	-1.7	-1.3	-1.4	-1.8	-1.7	-0.4	-1.0	-0.7	0.1	-1.3
Chronic bronchitis/emphysema (mother)	0.8	1.0	3.8	0.7	1.9	1.0	0.6	0.3	1.5	1.8	0.6	0.4	0.7	0.9	-0.6	1.1	0.4	0.8	0.5	0.9
Worry too long after embarrassment	0.8	1.4	3.3	1.1	-0.8	-1.0	-1.8	-0.3	-1.3	1.4	-0.5	-1.5	-1.2	-1.4	-1.7	0.5	-1.2	0.0	0.4	-1.7
Medication: Omeprazole	0.8	1.0	3.7	1.0	1.9	0.2	-1.3	-0.0	0.6	1.9	-0.2	0.4	-1.0	-0.8	-1.2	0.7	-0.0	0.6	1.0	-0.8
Number of full sisters	0.8	1.0	6.3	1.2	0.4	0.4	0.7	1.6	-1.2	0.4	2.5	-0.4	-0.4	0.5	0.5	0.7	0.7	1.2	0.3	-0.1
Suffer from ‘nerves’	0.8	1.3	5.3	2.0	-0.9	0.9	0.5	0.8	0.5	0.4	0.1	0.8	1.6	0.9	0.9	2.3	1.5	1.1	0.8	0.8
Mouth/teeth dental problems: Mouth ulcers	0.8	1.3	3.7	0.9	0.3	-1.2	-1.5	0.0	-0.3	1.9	-0.0	-1.4	-1.9	-1.4	-1.8	0.1	-1.1	-0.2	0.1	-1.2
Eye problems/disorders: Glaucoma	0.8	1.0	3.7	1.9	0.5	0.9	-0.5	-0.2	0.3	1.3	-0.1	1.2	0.4	0.3	0.5	1.2	1.1	1.4	1.7	-0.0
Age when periods started (menarche)	0.7	1.6	7.1	-0.7	-0.9	-1.1	-0.6	-1.1	-2.7	-0.3	-1.9	-1.2	0.2	-0.9	1.2	-0.8	-1.6	-1.3	-1.1	-1.5
Bilateral oophorectomy (both ovaries removed)	0.7	0.8	3.1	0.6	0.3	-0.7	-1.8	-0.3	0.0	0.8	-0.3	-0.6	-1.5	-1.3	-1.4	-0.1	-0.2	0.9	1.1	-0.8
Serious illness, injury or assault to yourself	0.7	0.9	2.0	0.5	-0.1	1.3	1.3	1.4	1.2	-0.2	0.8	1.1	1.1	1.4	0.9	0.6	0.8	0.5	0.0	1.1
Diverticular disease/diverticulitis (self-reported)	0.7	0.8	2.5	0.8	0.3	0.9	0.5	0.9	-0.7	1.4	1.6	0.5	0.2	0.5	1.2	1.4	0.8	1.3	0.8	-0.1
Medication: Ibuprofen (e.g. Nurofen)	0.7	0.9	3.4	0.3	-1.8	-1.2	-1.3	-1.3	-0.1	0.1	-0.0	-1.2	-1.4	-1.0	-1.0	-0.4	-0.4	-0.3	0.0	-0.6
Pulse wave Arterial Stiffness index	0.7	0.8	1.9	-0.1	0.5	1.1	0.5	1.3	0.1	0.5	0.6	0.7	1.0	0.8	1.2	1.0	0.9	1.3	1.4	0.5
Seen doctor (GP) for nerves, anxiety, tension or depression	0.7	1.1	2.3	1.3	0.3	0.8	1.1	1.5	-0.2	-1.3	1.1	0.7	1.1	1.1	1.3	1.5	1.3	0.4	0.3	0.9
Leg fat percentage (right)	0.7	2.6	7.0	-0.4	-1.4	0.5	2.7	2.2	0.2	-1.7	-0.5	1.3	1.2	1.8	1.4	-1.9	-0.1	-1.2	-2.5	2.5
Comparative body size at age 10	0.7	1.9	5.1	-0.7	-2.2	1.3	1.5	1.8	-0.0	-2.2	1.5	1.3	1.4	1.7	1.4	0.1	1.2	0.1	-0.4	1.2
Age at first live birth	0.7	1.2	3.1	-0.5	-0.9	-1.3	-0.6	-1.5	-1.4	0.3	-1.2	-1.5	-0.7	-0.9	-1.4	-0.2	-1.7	-1.3	-1.1	-0.8
Medication for pain relief, constipation, heartburn	0.7	1.1	4.5	-2.1	-0.4	-0.9	0.3	-0.5	-1.8	-1.4	-1.0	-0.6	-0.2	-0.4	-0.2	-1.7	-0.8	-0.9	-1.5	-0.2
Angina (self-reported)	0.7	0.9	3.1	1.8	0.4	0.7	0.0	0.6	1.3	1.7	0.3	1.0	0.7	0.3	0.5	1.4	0.5	0.8	1.3	-0.3
Mineral and other dietary supplements	0.7	0.9	4.5	-0.8	-0.0	0.7	0.8	0.9	2.1	0.7	1.3	0.7	0.4	0.6	0.1	1.9	1.0	0.3	1.1	0.2
Medication: Aspirin	0.7	1.0	2.7	1.6	-0.3	0.8	-0.2	1.0	1.2	1.5	0.8	0.8	0.1	0.4	0.4	1.5	0.6	1.1	1.7	0.0
Medication: Gliclazide	0.7	0.7	1.4	0.1	0.2	0.9	1.2	1.2	1.0	-0.8	1.2	1.1	0.6	1.1	0.8	0.4	1.1	0.2	-0.2	1.0
Tinnitus: Yes, now most or all of the time	0.7	0.8	1.8	-0.2	1.1	1.2	1.1	1.3	0.8	-1.0	-0.8	1.4	1.3	1.0	0.8	-0.0	0.5	0.2	-0.1	0.9
Age started oral contraceptive pill	0.7	0.8	3.8	-0.1	-1.9	-0.4	0.5	0.5	-1.9	-1.0	-0.2	-0.4	0.3	0.2	0.5	-0.8	-0.9	-1.0	-1.3	-0.6
Cholesterol lowering medication	0.7	1.1	3.8	0.7	0.6	-0.7	-1.6	-0.0	1.9	1.7	-0.1	-0.8	-0.7	-1.2	-1.4	0.7	-0.3	0.1	1.4	-0.9
Alzheimer’s Disease (including proxy)	0.6	0.8	3.2	0.5	1.7	-0.1	-1.3	-0.5	1.8	0.8	-0.4	-0.5	-0.9	-1.0	-1.0	0.0	0.1	0.1	1.1	-0.9
Irritable Bowel Disease (IBD)	0.6	1.3	5.5	-0.7	-2.1	-0.3	0.3	0.1	-1.1	-2.3	-1.8	-0.1	0.6	-0.0	1.4	-1.2	-0.7	-1.0	-1.5	0.6
HbA1C	0.6	0.7	2.0	0.7	0.8	0.6	0.1	-0.3	0.5	0.7	-0.2	-0.3	1.4	0.6	0.8	0.9	1.0	1.4	1.1	0.7
Lung FVC	0.6	2.8	6.0	-2.1	0.8	-1.9	-1.7	-2.4	-0.7	0.2	-1.8	-1.9	-1.6	-2.0	-1.7	-1.3	-2.2	-1.5	-0.6	-2.0
Relative age of first facial hair	0.6	1.3	4.8	0.2	0.6	-1.3	-1.4	-2.2	1.1	0.1	-1.3	-1.2	-0.5	-1.3	-1.9	-0.5	-0.7	-1.0	-0.2	-1.1
Ever used hormone-replacement therapy (HRT)	0.6	0.8	6.0	0.2	0.7	-0.5	-1.1	-0.4	-2.5	0.5	-0.8	-0.4	-0.9	-0.8	-0.8	-0.5	-0.9	0.1	0.0	-1.1
Current tobacco smoking	0.6	1.0	2.7	0.6	1.1	0.9	1.6	1.2	1.0	-0.0	0.3	0.9	1.4	1.4	1.1	0.4	0.9	0.6	-0.0	1.6
Tinnitus: Yes, but not now, but have in the past	0.6	0.6	2.6	0.6	1.0	-0.3	-1.6	-0.2	1.0	1.2	-0.1	-0.1	-0.4	-0.8	-0.8	0.5	0.3	0.8	1.4	-0.2
Qualifications: CSEs or equivalent	0.6	0.8	2.8	-0.2	-0.7	0.3	1.1	0.3	0.7	-1.7	1.0	0.7	0.9	0.9	0.9	0.7	1.2	-0.0	-0.1	1.2
Frequency of tenseness / restlessness in last 2 weeks	0.6	0.9	4.1	2.0	0.7	1.2	0.8	1.1	0.2	0.1	0.1	0.7	1.4	0.9	0.6	1.7	0.8	0.5	0.4	0.4
Mouth/teeth dental problems	0.6	0.9	5.4	-2.3	0.2	0.6	0.7	-0.5	-0.1	-1.8	1.0	0.7	0.6	0.9	1.1	-0.4	0.7	-0.1	-0.6	1.0
Diabetes (self-reported)	0.6	0.9	3.6	0.8	0.5	-0.4	-1.3	-0.8	1.9	1.3	-0.8	-0.4	-0.7	-1.0	-0.6	0.5	-0.2	0.2	1.6	-1.2
Hayfever/allergic rhinitis (self-reported)	0.6	0.8	3.3	1.0	0.9	-0.2	-1.0	-1.3	1.8	0.2	1.0	-0.1	-0.9	-0.6	-0.8	0.2	0.7	0.6	1.3	-0.5
Depression (self-reported)	0.6	0.8	3.1	1.0	-1.7	0.2	-0.5	0.2	-1.8	1.1	-0.5	-0.3	0.5	-0.0	1.3	0.9	0.4	1.0	0.6	-0.3
Peak expiratory flow (PEF)	0.6	1.4	7.3	-1.4	-2.7	0.2	1.6	1.9	-0.0	-1.9	1.3	0.3	-0.0	0.9	0.5	-0.2	0.6	-0.2	-0.7	1.2
Overall health rating	0.6	1.2	6.1	2.5	0.4	1.2	0.9	1.6	0.5	1.0	0.5	1.1	1.2	1.0	1.1	1.6	0.7	0.6	0.5	0.6
Illness, injury, bereavement, stress in last 2 years	0.6	0.8	4.6	1.3	0.5	-0.3	-1.0	-0.9	-0.7	2.1	-0.2	-0.2	-0.3	-0.8	-0.6	0.8	-0.5	0.6	0.9	-1.0
Smoking status: Current	0.6	0.9	2.9	0.4	0.7	0.9	1.5	1.0	0.9	-0.1	0.2	0.8	1.5	1.4	1.1	0.3	0.9	0.6	-0.1	1.7
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.6	1.4	4.2	-1.6	-0.9	-1.2	-1.6	-0.5	0.1	-0.2	-0.0	-0.8	-2.1	-1.4	-1.8	-1.3	-1.1	-0.8	-0.4	-1.2
Guilty feelings	0.6	0.9	5.0	0.7	-1.0	-0.5	0.2	1.1	-2.2	-1.1	-1.0	-0.7	-0.2	-0.7	0.4	-0.2	-0.9	-1.0	-1.5	-0.6
Illnesses of father: High blood pressure	0.6	0.7	3.1	-0.2	-0.1	0.0	-1.2	0.3	0.0	0.7	0.7	-0.2	-1.2	-0.8	-1.2	0.5	0.1	0.7	1.8	-1.4
Alcohol drinker status: Never	0.6	0.7	2.0	0.0	-0.4	0.9	0.5	0.4	-0.2	0.1	-0.3	1.0	1.1	0.9	1.4	0.6	0.9	1.3	0.5	1.4
Depression (Nagel 2018)	0.5	0.8	4.5	0.6	-2.1	-0.4	0.1	-0.4	-0.2	-1.2	-1.8	-0.3	0.9	-0.1	0.2	0.1	-0.5	-1.2	-0.5	-0.4
Reaction Time	0.5	0.9	2.9	0.5	0.6	1.0	1.3	1.7	-0.6	0.6	1.5	0.6	1.0	1.3	0.8	1.3	0.4	0.3	-0.6	0.2
Breast Cancer	0.5	1.2	3.4	-0.2	-1.8	0.6	1.6	1.4	-1.1	-1.1	-0.6	-0.0	1.5	0.9	1.8	0.2	0.8	0.5	-0.5	1.3
Lupus	0.5	0.8	2.1	0.6	1.5	0.6	0.3	0.3	0.9	0.6	0.8	0.8	1.0	1.0	1.2	0.4	0.9	0.7	1.0	1.4
Vitamin and mineral supplements	0.5	0.7	3.2	-1.8	-0.4	-0.0	1.4	0.1	-0.8	-1.5	-0.1	-0.1	0.2	0.4	0.1	-0.2	-0.3	-1.2	-1.4	0.2
Qualifications: None of the above	0.5	1.0	3.8	-1.9	1.7	-0.3	0.9	1.1	0.1	-1.9	-0.5	-0.0	0.3	0.3	0.7	-1.0	-0.4	-1.3	-1.2	0.2
Financial difficulties in last 2 years	0.5	0.6	2.4	1.6	0.7	0.9	0.7	0.3	0.6	-0.0	0.8	0.8	0.4	0.9	0.5	0.6	1.3	0.6	0.4	0.9
Pulse wave reflection index	0.5	0.6	3.1	-0.9	-1.8	-0.6	-0.4	-0.0	-0.4	-0.9	-1.4	-0.5	-0.3	-0.7	0.2	-1.0	-0.6	-0.4	-0.4	-0.1
Number of full brothers	0.5	0.7	1.3	-1.1	0.9	-0.9	-0.6	-0.7	0.7	0.2	-1.0	-0.6	-0.8	-1.0	-0.9	-0.5	-0.8	-1.1	-0.7	-0.3
Medication: Allopurinol	0.5	0.7	2.7	0.0	0.5	-0.6	-1.4	-1.5	-0.0	-0.0	0.7	-0.5	-1.1	-1.0	-0.7	0.2	0.0	0.3	0.9	-1.6
Heart disease (mother)	0.5	0.6	2.2	-1.1	-0.0	-0.6	0.3	0.8	-0.8	-1.1	-0.4	-0.1	-0.6	-0.3	-0.1	-0.8	-0.8	-1.2	-1.5	0.2
Leg pain on walking	0.5	0.6	1.5	1.2	0.3	1.0	0.3	0.8	-0.2	0.3	0.4	0.7	1.0	0.9	0.9	1.1	0.8	0.9	0.8	0.4
Qualifications: NVQ or HND or HNC or equivalent	0.5	0.6	3.3	0.5	1.8	0.5	-0.1	0.0	0.9	0.3	0.4	0.8	0.7	0.5	0.2	0.3	1.1	0.8	1.0	0.5
Loneliness, isolation	0.5	0.7	4.0	2.0	-0.2	0.9	1.0	0.6	-0.6	-0.6	0.8	0.4	0.9	0.8	0.7	1.4	0.8	0.0	-0.3	0.6
Friendships satisfaction	0.5	0.6	2.4	1.0	-1.0	-0.8	-1.5	0.2	0.5	0.1	-1.0	-1.0	-0.5	-1.1	-0.7	0.5	-0.3	-0.1	0.4	-0.4
Financial situation satisfaction	0.5	0.6	3.6	1.9	0.8	0.4	-0.3	0.7	0.1	0.7	-0.5	0.6	0.2	-0.3	-0.2	1.5	0.5	0.5	1.0	-0.5
Pain type(s) experienced in last month: Hip pain	0.5	0.7	2.0	-1.3	1.4	-0.6	-0.0	-0.3	0.5	0.1	-0.6	-0.4	-0.9	-0.4	-1.0	-1.2	-0.9	-0.9	-1.0	0.1
Medication: Lisinopril	0.5	0.6	3.4	1.0	1.5	0.2	0.1	0.8	0.3	1.9	0.3	0.4	0.3	0.1	-0.6	1.4	0.2	0.6	0.5	0.1
Diastolic blood pressure, automated reading	0.5	1.6	6.0	1.0	-2.4	1.0	-0.3	2.2	-0.4	1.8	0.1	1.3	0.1	0.2	0.4	1.4	0.8	1.7	2.1	-0.1
Basal cell carcinoma (self-reported)	0.5	0.6	1.6	-1.1	0.2	-0.7	-0.7	0.0	0.4	0.9	0.4	-0.8	-1.3	-0.7	-1.0	-0.7	-1.1	-0.5	-0.1	-0.8
Alzheimer’s Disease (in mother)	0.4	0.5	2.3	0.1	1.5	-0.4	0.1	-0.9	0.7	-0.7	-0.2	-0.3	-0.6	-0.6	-0.3	-0.7	-0.3	-1.2	-0.8	-0.6
Verbal and Numeric Reasoning (VNR)	0.4	1.0	7.6	-0.3	-2.8	-0.3	0.2	0.1	-2.1	0.0	-1.4	-0.1	0.1	-0.1	0.1	-1.0	-0.9	-0.2	-0.8	-0.3
Systolic Blood Pressure	0.4	2.2	9.2	0.3	-1.6	1.0	-0.1	3.0	-1.2	1.7	-0.2	1.1	1.0	0.3	2.5	1.8	1.0	1.6	2.0	0.2
Type 2 Diabetes (T2D) (2018)	0.4	0.8	2.7	1.4	0.1	0.5	0.0	0.5	1.6	1.3	0.1	0.3	0.5	0.1	0.5	1.6	0.8	0.9	1.5	-0.2
Frequency of depressed mood in last 2 weeks	0.4	0.6	4.1	0.5	-1.4	-0.3	0.1	0.1	0.2	-1.0	-2.0	-0.2	0.9	-0.1	0.5	0.2	-0.4	-0.8	-0.2	-0.1
Systolic blood pressure, automated reading	0.4	1.0	5.7	0.4	-1.2	0.6	-0.1	2.4	-0.4	0.9	-0.0	0.8	0.5	0.2	1.7	0.7	0.7	1.1	1.7	-0.2
Medication: Co-codamol	0.4	0.5	2.7	1.6	1.0	-0.4	-0.2	0.2	-0.9	0.7	0.7	-0.2	-0.7	-0.4	-0.3	0.1	-0.4	-0.1	-0.2	-1.0
Had other major operations	0.4	0.5	1.7	0.6	-1.2	0.9	0.4	-0.2	-1.3	0.0	0.2	1.0	0.8	1.0	0.6	0.6	0.6	0.9	0.1	0.5
Illnesses of siblings	0.4	0.6	1.7	-0.6	0.4	-1.0	0.1	-0.9	0.3	-1.3	-0.4	-1.2	-0.1	-0.4	-0.7	-0.7	-0.5	-1.1	-1.0	-0.5
Arm fat percentage (right)	0.4	1.5	5.2	0.6	1.4	0.8	1.9	1.7	1.9	-0.2	0.8	1.2	0.9	1.6	0.1	-0.1	0.9	-0.2	-1.0	2.3
Time employed in main current job	0.4	0.5	2.1	-1.2	-0.3	-0.0	0.7	0.9	-0.3	-1.2	1.5	-0.5	-0.3	0.3	0.1	0.0	-0.3	-0.9	-0.7	0.3
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.4	1.3	-0.8	0.0	-0.9	-1.0	-0.9	0.8	-0.0	0.1	-1.2	-0.8	-0.6	-0.6	-0.3	-0.4	-0.4	-0.1	-0.2
Tense / ‘highly strung’	0.4	0.6	2.8	1.4	0.2	0.2	-0.6	0.1	0.0	1.0	0.6	-0.6	0.2	-0.2	-0.1	1.7	0.3	0.6	1.2	-1.1
Wheeze or whistling in the chest in last year	0.4	0.7	1.5	0.4	1.2	-0.6	0.1	-0.9	0.2	0.8	-1.2	-0.3	-1.1	-1.0	-1.2	-0.1	-1.2	-1.1	-0.9	-0.7
Qualifications: College or University degree	0.4	1.1	7.1	-0.1	-2.7	-0.4	-0.8	-1.3	-1.9	1.2	0.3	-1.2	-0.7	-0.4	-0.4	-0.3	-1.0	0.1	-0.2	-1.0
Emphysema/chronic bronchitis	0.4	0.4	2.4	0.5	1.6	-0.4	-1.0	-0.3	0.5	0.4	0.2	-0.9	-0.8	-0.7	-0.8	0.2	0.0	0.3	0.2	-0.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.4	0.5	2.1	-0.1	-1.0	-0.3	0.7	0.8	-0.1	-0.8	0.6	-0.1	-0.5	0.3	0.5	-1.1	-0.4	-0.9	-1.4	0.8
Family relationship satisfaction	0.4	0.5	1.8	0.5	-1.1	0.1	-0.9	-0.6	1.3	-0.8	-1.0	0.4	0.6	-0.3	0.5	0.3	0.5	0.2	0.7	0.3
Knee pain experienced in last month	0.4	0.6	2.2	0.0	1.5	-0.1	0.7	-0.6	0.7	-0.4	0.6	-0.4	-0.4	0.4	-0.7	-1.1	-0.3	-0.7	-1.5	0.9
Illnesses of father: Heart disease	0.4	0.5	2.4	0.4	-0.7	0.0	1.1	1.5	0.1	-0.4	-0.6	0.5	0.0	0.3	-0.4	-0.2	-0.4	-0.6	-1.3	0.7
Illnesses of siblings: Diabetes	0.4	0.5	1.8	0.2	0.8	-0.4	0.1	-0.1	0.5	-1.4	-0.5	0.1	-0.7	-0.6	-1.0	-0.7	-0.3	-1.1	-0.9	-0.1
Arm fat percentage (left)	0.4	1.6	5.8	0.6	1.0	0.9	2.0	1.7	1.7	-0.2	0.7	1.3	1.2	1.7	0.4	-0.1	0.9	-0.2	-1.0	2.4
Diabetes diagnosed by doctor	0.4	0.6	6.8	0.7	0.6	-0.2	-0.6	-0.2	2.6	0.2	-0.6	-0.0	-0.2	-0.4	-0.2	0.4	0.2	0.0	1.0	-0.2
Eye problems/disorders: Cataract	0.4	0.4	2.2	1.5	-0.5	0.1	-0.7	-0.9	-0.2	0.3	-0.4	0.1	0.5	-0.1	0.2	0.9	0.5	0.8	0.9	-0.5
Illnesses of father: None of the above (group 1)	0.4	0.5	2.3	-1.0	-0.1	-0.9	-0.7	-1.5	-0.7	0.0	0.1	-0.8	-0.3	-0.5	0.2	-0.8	-0.6	-0.3	-0.5	-0.4
Hearing aid user	0.4	0.5	2.9	0.6	-1.1	0.5	0.4	1.7	0.8	0.2	0.8	0.1	0.5	0.6	0.7	0.3	0.5	0.6	0.4	0.5
Supplements: Fish oil (including cod liver oil)	0.4	0.5	2.2	0.9	0.2	-0.5	-1.5	-0.6	-0.6	0.1	-1.0	-0.4	-0.7	-0.8	-0.7	-1.2	-0.3	0.5	0.3	-0.2
Average weekly beer plus cider intake	0.4	0.5	2.6	-0.0	0.6	0.4	0.8	0.3	-1.6	-1.4	-0.2	0.4	0.6	0.6	1.0	-0.1	0.1	-0.4	-0.8	0.6
Myopia	0.4	0.5	4.1	0.4	-0.5	-0.3	0.6	-0.5	-0.9	-2.0	0.0	-0.3	0.3	0.3	0.3	-0.5	-0.0	-0.9	-1.3	0.5
Body Mass Index (BMI) (2010)	0.3	0.4	2.0	0.1	-1.0	-0.3	-0.5	1.4	-0.1	0.3	0.8	-0.5	-1.0	-0.4	-0.0	-0.4	-0.3	-0.0	0.3	-0.6
Ever had hysterectomy (womb removed)	0.3	0.4	1.3	-0.3	1.1	0.3	0.8	1.0	-0.0	-1.0	0.3	0.1	-0.3	0.2	-0.7	-0.2	0.3	-0.1	-1.0	0.8
Townsend deprivation index at recruitment	0.3	0.5	2.4	-1.4	1.5	-0.4	-0.2	-0.3	0.7	-0.8	-0.0	-0.3	-0.2	-0.2	-0.2	-1.0	-0.2	-0.7	-0.5	-0.4
Frequency of unenthusiasm / disinterest in last 2 weeks	0.3	0.4	1.5	0.7	-0.5	0.0	0.9	0.5	-0.4	-0.9	-1.0	-0.1	1.2	0.4	0.4	0.6	-0.2	-0.9	-0.6	-0.0
Hayfever, allergic rhinitis or eczema	0.3	0.7	4.4	1.5	1.0	0.1	-0.8	-2.1	0.1	0.5	1.1	0.3	-0.8	-0.2	-0.9	0.0	0.3	0.7	0.5	-0.7
Number of incorrect matches in round	0.3	0.4	1.8	0.9	-0.6	-0.4	-0.7	-0.7	1.0	-0.9	0.6	-0.5	-0.7	-0.2	-1.3	-0.6	-0.0	-0.3	-0.2	0.1
Alcohol usually taken with meals	0.3	0.5	1.7	-1.1	0.2	-0.7	-0.1	-0.2	0.6	0.1	0.5	-0.8	-1.2	-0.5	-1.1	-1.3	-0.5	-0.5	-0.6	0.2
Hearing difficulty/problems with background noise	0.3	0.5	3.0	1.7	-1.0	-0.1	-0.2	-0.4	0.5	0.1	-1.6	-0.1	0.4	-0.5	-0.2	0.4	-0.2	-0.1	-0.3	0.1
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.4	2.0	1.4	0.1	-0.0	0.6	0.6	0.4	-0.4	-1.0	-0.2	1.0	0.4	-0.1	0.5	-0.2	-0.7	-0.7	0.9
Qualifications: A levels/AS levels or equivalent	0.3	0.7	3.5	0.5	-1.4	-0.2	-1.1	-0.6	0.3	1.9	0.0	-0.4	-0.7	-0.7	-1.4	0.9	-0.1	0.8	0.8	-0.5
Mouth/teeth dental problems: Dentures	0.3	0.5	3.2	1.5	1.8	0.3	1.0	0.4	-0.7	0.2	-0.3	0.3	0.7	0.6	0.3	-0.4	-0.2	-0.1	-0.5	0.1
Medication: Lansoprazole	0.3	0.3	2.2	0.7	1.5	-0.4	-0.2	-0.6	-0.5	0.7	-0.7	-0.2	-0.0	-0.2	-0.1	-0.0	-0.5	-0.1	-0.2	-0.2
Exposure to tobacco smoke at home	0.3	0.3	1.7	0.5	-1.1	-0.0	0.4	1.3	-0.5	-0.7	-0.2	0.1	-0.1	0.2	0.2	-0.8	-0.1	-0.5	-0.8	0.1
Hair/balding pattern: Pattern 4	0.3	0.8	3.3	1.8	-1.8	0.0	-0.9	-0.3	-0.0	1.2	-0.3	0.5	-0.2	-0.4	0.4	0.8	0.7	1.2	1.4	0.1
Reason for reducing amount of alcohol drunk: Health precaution	0.3	0.3	1.4	1.2	0.1	0.0	-1.0	-1.1	-0.3	0.4	0.0	-0.3	-0.2	-0.4	-0.3	0.9	0.1	0.3	0.8	-0.5
Pulse wave peak to peak time	0.3	0.3	1.4	0.4	-0.6	-0.5	0.0	-0.7	-0.0	-0.9	-0.0	-0.1	-0.5	-0.2	-0.6	-0.8	-0.3	-0.8	-1.2	0.0
Medication: Ibuprofen	0.3	0.4	2.6	0.8	-1.6	0.0	-0.3	0.1	0.5	0.4	1.0	0.0	-0.5	0.1	0.2	0.5	0.6	0.6	0.7	0.0
Age at last live birth	0.3	0.4	1.5	0.1	-1.1	-0.6	-0.4	-1.2	-0.8	0.2	-0.6	-0.6	0.2	-0.1	-0.4	-0.1	-0.8	-0.7	-0.8	-0.1
Average weekly red wine intake	0.3	0.5	2.2	-1.1	-1.5	-1.1	-0.5	-0.7	-0.2	0.5	-0.8	-0.7	-0.5	-0.7	-0.5	-0.7	-0.6	-0.5	-0.2	-0.1
Ever had stillbirth, spontaneous miscarriage or termination	0.3	0.4	1.9	0.8	-1.4	0.4	0.2	-0.0	-0.0	0.4	1.0	0.3	-0.1	0.2	0.9	0.9	0.5	0.4	0.3	0.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.3	0.3	1.3	0.3	-0.2	0.4	0.9	1.1	-0.6	-0.9	-0.4	0.3	0.6	0.6	0.1	0.1	-0.1	-0.5	-0.6	0.8
Breast cancer (self-reported)	0.3	0.3	1.0	-0.5	-0.4	-0.6	-0.3	-0.9	0.8	-0.2	-0.4	-0.1	0.2	-0.1	-0.5	-0.7	-0.8	-1.0	-0.6	-0.2
Risk taking	0.3	0.4	1.6	-1.2	0.2	-0.1	0.6	0.3	0.3	-0.7	-0.1	-0.6	0.2	0.0	0.2	-0.3	-0.6	-1.1	-1.3	0.2
Bipolar Disorder (2018)	0.2	0.3	1.3	0.0	0.0	-0.1	-0.1	-1.1	-0.8	0.2	0.0	-0.4	0.8	-0.4	1.2	0.0	-0.5	-0.3	0.0	-0.0
Intelligence (Savage-Jansen 2018)	0.2	0.6	2.6	-0.4	-0.7	-0.4	-0.9	-0.2	-0.8	1.6	-0.9	-0.3	-0.8	-0.5	-0.8	-1.0	-1.0	0.4	0.1	-0.4
Crohns Disease (2012)	0.2	0.3	1.2	-0.3	-0.1	0.0	-0.2	1.1	-1.1	-0.2	0.5	-0.1	-0.2	-0.2	0.8	-0.3	0.0	0.4	0.5	-0.6
Fasting Glucose	0.2	0.2	1.1	-0.5	0.5	-0.0	0.2	0.0	0.4	0.2	-1.1	-0.3	0.6	0.3	-0.1	0.7	-0.1	-0.1	-0.2	0.7
HDL Cholesterol	0.2	0.3	1.4	-0.6	-0.8	0.0	0.5	0.1	-0.8	0.2	-0.3	-0.3	-0.3	0.3	-0.4	-0.5	-0.6	-0.4	-1.2	0.4
Primary Biliary Cirrhosis	0.2	0.3	0.9	-0.6	0.2	0.7	0.8	0.4	0.2	-0.6	0.4	0.8	0.6	0.8	0.6	0.1	0.5	0.1	-0.4	0.9
Schizophrenia (2014)	0.2	0.4	3.3	0.0	0.0	1.5	0.8	1.8	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Blood Eosinophil Count	0.2	1.3	2.8	-0.4	0.2	1.2	1.5	-0.1	1.6	-1.4	1.6	1.5	1.2	1.7	0.7	-0.2	1.3	0.3	-0.7	1.5
Allergy or Eczema	0.2	0.6	3.3	1.3	0.9	0.2	-0.6	-1.8	-0.1	-0.3	1.2	0.4	-0.7	-0.2	-0.5	-0.2	0.3	0.7	0.6	-0.8
Hearing difficulty/problems: Yes	0.2	0.3	2.4	0.8	-0.4	-0.1	0.1	-0.2	0.9	1.0	-1.5	0.1	0.3	-0.3	-0.0	0.4	-0.2	0.1	0.3	0.0
Supplements: Zinc	0.2	0.3	0.9	0.5	-0.5	0.4	0.2	0.6	-0.7	0.2	0.7	-0.0	0.0	0.3	0.9	0.4	0.3	0.6	-0.1	0.8
Pulse rate	0.2	0.4	1.9	-1.0	1.4	0.7	0.5	-0.3	-0.1	0.2	0.5	-0.0	1.1	0.7	-0.0	1.2	0.4	-0.1	-0.0	0.2
Happiness	0.2	0.2	0.9	0.6	0.5	-0.1	-0.2	0.1	0.5	-0.9	-0.4	-0.1	0.2	-0.2	-0.9	0.3	0.2	-0.5	-0.4	0.3
Lung cancer (father)	0.2	0.3	1.7	0.2	-0.8	0.3	-0.0	0.6	0.3	0.1	1.3	0.2	-0.3	0.3	0.3	0.7	0.4	0.2	0.5	-0.4
Ever highly irritable/argumentative for 2 days	0.2	0.2	1.0	0.1	-0.5	-0.1	-0.2	-0.5	0.8	0.6	0.1	-0.0	-0.1	-0.3	-0.3	1.0	0.2	0.4	0.5	-0.4
Medication: Paracetamol	0.2	0.3	2.0	1.4	-0.0	0.5	0.4	0.0	0.4	-0.7	1.2	0.3	0.0	0.3	0.2	0.8	0.7	0.0	0.3	-0.2
Exposure to tobacco smoke outside home	0.2	0.3	1.3	0.9	-1.1	-0.4	0.2	1.1	0.4	-0.8	-0.4	0.1	0.2	0.0	0.1	-0.6	0.0	-0.2	0.0	0.1
Pulse rate, automated reading	0.2	0.7	6.1	0.2	0.5	0.1	-0.9	-1.4	0.4	2.5	-0.2	-0.4	0.2	-0.1	-0.8	0.8	-0.4	0.4	0.8	-0.3
Alcohol intake frequency.	0.2	0.4	2.6	-1.6	-0.5	-0.7	0.1	0.4	0.3	-0.6	-0.6	-1.0	0.1	-0.4	0.4	-0.3	-0.3	-0.8	-0.5	-0.1
Chest pain or discomfort	0.2	0.3	1.5	-0.6	0.4	0.1	0.3	0.9	1.2	0.4	-0.9	0.2	-0.0	0.0	-0.3	0.1	-0.4	-0.5	-0.5	0.5
Supplements: Vitamin C	0.2	0.3	1.1	0.3	-0.1	0.3	-0.1	0.2	-1.1	0.8	1.0	-0.2	-0.7	0.1	-0.6	-0.0	-0.2	0.1	-0.4	-0.2
Handedness (chirality/laterality): Left-handed	0.2	0.2	0.9	0.1	-0.3	-0.2	-0.6	-0.0	0.4	0.3	0.2	-0.5	-0.4	-0.3	-0.5	-0.5	-0.4	0.3	0.3	-1.0
Ever taken oral contraceptive pill	0.2	0.2	0.6	0.2	-0.5	-0.1	-0.2	-0.1	-0.2	0.8	-0.7	-0.0	0.3	-0.3	0.4	0.8	-0.1	0.2	0.6	-0.4
Ever had prostate specific antigen (PSA) test	0.2	0.2	1.3	0.5	0.8	0.4	-0.1	0.0	-0.5	1.1	0.5	0.4	-0.2	0.2	0.3	-0.0	-0.2	0.5	0.1	0.0
Commuting to job workplace: Cycle	0.2	0.3	1.1	1.1	-0.8	0.2	-0.4	-0.8	0.0	0.5	0.7	-0.1	0.1	-0.0	0.0	0.7	0.4	0.6	0.6	-0.6
Schizophrenia vs Biploar Disorder	0.1	0.2	2.1	0.0	0.0	0.9	0.1	1.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Coronary Artery Disease (CAD)	0.1	0.1	2.1	0.0	0.0	0.0	0.0	1.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Blood Platelet Count	0.1	0.9	5.8	0.4	2.4	0.2	0.0	-1.5	2.1	0.6	0.5	0.6	0.4	0.5	-1.0	-0.3	0.5	-0.2	-0.0	0.6
Blood Red Count	0.1	1.2	3.2	-1.6	-1.5	-1.2	-1.0	0.6	-0.2	1.1	-1.2	-0.9	-1.6	-1.3	-1.8	-0.5	-1.3	-0.1	-0.0	-0.2
Hair Pigment	0.1	1.5	4.8	-0.3	0.9	-1.5	-1.0	-1.0	0.3	-0.6	0.2	-1.5	-2.0	-1.2	-2.2	-1.4	-1.1	-1.4	-1.6	0.1
Tanning	0.1	1.1	5.3	-2.1	-0.2	-0.9	-0.5	-0.9	-0.3	-0.5	-2.3	-0.8	-0.4	-1.1	-0.3	-0.9	-1.1	-1.1	-0.3	-1.2
Mouth/teeth dental problems: Loose teeth	0.1	0.1	0.6	0.4	-0.1	-0.2	0.0	0.5	0.6	-0.2	-0.7	0.1	0.3	-0.0	-0.2	0.1	-0.0	-0.3	0.1	0.1
Neck or shoulder pain in last month	0.1	0.2	0.9	0.4	-0.1	-0.4	-0.6	0.1	0.0	0.8	-0.2	-0.6	-0.5	-0.6	-0.9	0.3	-0.3	-0.1	-0.0	-0.2
Osteoarthritis (self-reported)	0.1	0.2	1.2	0.2	0.1	0.6	0.6	-0.3	0.5	0.4	0.3	1.1	-0.0	0.5	-0.4	-0.4	-0.0	-0.0	-0.3	0.1
Medication: Paracetamol	0.1	0.2	1.1	1.0	0.0	-0.0	-0.1	-0.1	0.3	0.1	0.5	0.0	-0.4	-0.3	-0.1	0.7	0.1	-0.1	0.4	-0.8
Alcohol drinker status: Previous	0.1	0.1	0.3	0.0	0.3	-0.5	0.1	-0.3	-0.1	0.0	0.5	-0.5	0.1	-0.1	0.1	-0.1	-0.1	-0.5	-0.5	-0.6
Bipolar Disorder or Schizophrenia	0.0	0.0	0.1	0.0	0.0	0.2	-0.3	-0.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Schizophrenia (2018)	0.0	0.0	0.1	0.0	0.0	0.3	-0.4	0.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Major Depression (MDD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Type 2 Diabetes (T2D) (2012)	0.0	0.0	0.4	0.0	0.0	0.4	-0.1	0.6	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0

Hub : Genes

MLST8

Models

Trait associations