[Hub]/) : Traits : Leg fat mass (right) : ← →

chr17:27,222,988-29,547,601

Best TWAS P=3.26e-10 · Best GWAS P=2.57e-10 conditioned to 0.0598

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex EFCAB5 0.11 0.18 blup 392 0.17 1.7e-20 -5.4 -5.9 4.2e-09 0.91 0.18 0.82 FALSE
2 GTEx Brain Cortex GOSR1 0.20 0.20 enet 7 0.18 1.4e-05 4.5 5.2 2.0e-07 -0.50 0.73 0.14 FALSE
3 GTEx Brain Nucleus accumbens basal ganglia CORO6 0.11 0.10 lasso 2 0.05 2.2e-02 -5.1 5.2 2.0e-07 -0.89 0.07 0.72 FALSE
4 GTEx Lung SSH2 0.08 0.05 lasso 6 0.06 2.7e-05 -4.3 -5.4 5.5e-08 0.87 0.54 0.46 FALSE
5 GTEx Thyroid ANKRD13B 0.23 0.12 lasso 6 0.18 2.3e-13 -3.8 -5.9 2.7e-09 0.67 0.24 0.76 FALSE
6 The Cancer Genome Atlas Breast Invasive Carcinoma EFCAB5 0.02 0.04 lasso 4 0.04 1.9e-08 -5.4 -5.2 2.1e-07 0.92 0.07 0.93 FALSE
7 The Cancer Genome Atlas Colon Adenocarcinoma CCDC55 0.15 0.01 blup 64 0.04 1.9e-03 -5.7 6.3 3.3e-10 -0.85 0.02 0.60 TRUE
8 The Cancer Genome Atlas Colon Adenocarcinoma EFCAB5 0.06 0.05 blup 79 0.03 5.7e-03 -5.4 -5.4 7.6e-08 0.92 0.04 0.93 FALSE
9 The Cancer Genome Atlas Esophageal Carcinoma CCDC55 0.27 0.00 blup 64 0.00 3.5e-01 -1.0 5.3 9.2e-08 -0.61 0.01 0.37 FALSE
10 The Cancer Genome Atlas Lung Squamous Cell Carcinoma EFCAB5 0.04 0.04 lasso 4 0.05 5.9e-06 -4.7 -5.2 2.3e-07 0.84 0.07 0.93 FALSE
11 The Cancer Genome Atlas Prostate Adenocarcinoma EFCAB5 0.04 0.03 enet 10 0.02 6.0e-03 -5.2 -5.7 1.2e-08 0.85 0.04 0.93 FALSE
12 The Cancer Genome Atlas Soft Tissue Sarcoma EFCAB5 0.06 0.07 lasso 2 0.05 8.2e-04 -5.4 -5.2 1.6e-07 0.92 0.05 0.94 FALSE
13 The Cancer Genome Atlas Thyroid Carcinoma EFCAB5 0.11 0.18 enet 13 0.20 5.8e-19 -5.4 -5.4 6.2e-08 0.92 0.10 0.89 FALSE