Best TWAS P=4.98e-11 · Best GWAS P=3.59e-13 conditioned to 4.52e-06
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | PEF1 | 0.04 | 0.04 | lasso | 4 | 0.03 | 2.8e-04 | -5.1 | 5.1 | 2.8e-07 | -0.39 | 0.85 | 0.02 | FALSE |
| 2 | CommonMind | Brain Pre-frontal Cortex | S100PBP | 0.05 | 0.04 | enet | 10 | 0.02 | 1.2e-03 | -6.2 | 5.3 | 1.0e-07 | 0.14 | 0.01 | 0.99 | FALSE |
| 3 | CommonMind | Brain Pre-frontal Cortex | TMEM54 | 0.05 | 0.00 | blup | 281 | 0.02 | 4.5e-03 | 1.0 | -6.4 | 1.4e-10 | -0.10 | 0.10 | 0.31 | TRUE |
| 4 | CommonMind | Brain Pre-frontal Cortex | ZNF362 | 0.05 | 0.06 | lasso | 1 | 0.06 | 2.2e-07 | -5.3 | -5.3 | 1.4e-07 | 0.03 | 0.42 | 0.58 | FALSE |
| 5 | GTEx | Cells EBV-transformed lymphocytes | PHC2 | 0.58 | 0.34 | lasso | 7 | 0.28 | 7.3e-10 | -5.4 | 5.5 | 4.0e-08 | -0.01 | 0.15 | 0.85 | TRUE |
| 6 | GTEx | Muscle Skeletal | FNDC5 | 0.15 | 0.16 | enet | 5 | 0.16 | 1.9e-15 | -5.9 | -5.9 | 3.7e-09 | -0.16 | 0.03 | 0.97 | FALSE |
| 7 | GTEx | Thyroid | BAI2 | 0.31 | 0.23 | lasso | 6 | 0.22 | 1.4e-16 | 6.5 | 6.6 | 5.0e-11 | -0.28 | 0.25 | 0.75 | TRUE |
| 8 | ROSMAP | Brain Pre-frontal Cortex | PEF1 | 0.04 | 0.04 | lasso | 3 | 0.02 | 4.2e-04 | -5.0 | 5.3 | 1.2e-07 | -0.44 | 0.75 | 0.08 | TRUE |
| 9 | The Cancer Genome Atlas | Breast Invasive Carcinoma | S100PBP | 0.03 | 0.02 | blup | 46 | 0.02 | 6.6e-06 | -6.1 | 5.8 | 6.5e-09 | 0.14 | 0.01 | 0.99 | FALSE |
| 10 | The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | S100PBP | 0.06 | 0.03 | blup | 48 | 0.06 | 6.8e-04 | -6.0 | 6.3 | 3.4e-10 | 0.12 | 0.01 | 0.81 | TRUE |
| 11 | The Cancer Genome Atlas | Glioblastoma Multiforme | S100PBP | 0.21 | 0.15 | lasso | 5 | 0.15 | 2.9e-05 | -5.9 | 5.9 | 4.1e-09 | 0.16 | 0.01 | 0.92 | FALSE |
| 12 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | S100PBP | 0.04 | 0.04 | lasso | 4 | 0.04 | 2.3e-05 | -6.1 | 6.1 | 1.1e-09 | 0.16 | 0.01 | 0.99 | FALSE |
| 13 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | FNDC5 | 0.03 | 0.04 | enet | 6 | 0.03 | 2.9e-04 | -6.0 | -5.5 | 4.9e-08 | -0.14 | 0.01 | 0.98 | FALSE |
| 14 | The Cancer Genome Atlas | Brain Lower Grade Glioma | S100PBP | 0.06 | 0.06 | blup | 47 | 0.05 | 5.2e-06 | -6.1 | 6.1 | 1.3e-09 | 0.14 | 0.01 | 0.99 | FALSE |
| 15 | The Cancer Genome Atlas | Lung Adenocarcinoma | COL16A1 | 0.04 | 0.03 | lasso | 4 | 0.03 | 5.2e-04 | 6.6 | -5.6 | 2.2e-08 | 0.23 | 0.05 | 0.68 | FALSE |