Best TWAS P=1.94e-09 · Best GWAS P=2.46e-09 conditioned to 3.09e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | KIAA1429 | 0.16 | 0.13 | lasso | 2 | 0.11 | 9.5e-09 | -5.1 | 5.1 | 3.0e-07 | 0.31 | 0.37 | 0.63 | FALSE |
| 2 | GTEx | Testis | KIAA1429 | 0.29 | 0.22 | enet | 21 | 0.22 | 3.3e-10 | -5.1 | 6.0 | 1.9e-09 | 0.34 | 0.24 | 0.76 | TRUE |
| 3 | METSIM | Adipose | KIAA1429 | 0.04 | 0.03 | lasso | 7 | 0.03 | 1.8e-05 | -5.1 | 5.2 | 1.8e-07 | 0.31 | 0.10 | 0.89 | FALSE |
| 4 | NTR | Blood | RAD54B | 0.03 | 0.02 | lasso | 3 | 0.02 | 3.7e-06 | -5.3 | -5.3 | 8.9e-08 | -0.25 | 0.15 | 0.84 | FALSE |
| 5 | The Cancer Genome Atlas | Thyroid Carcinoma | KIAA1429 | 0.10 | 0.05 | blup | 57 | 0.08 | 4.1e-08 | -5.1 | 5.1 | 2.8e-07 | 0.33 | 0.12 | 0.88 | FALSE |