Best TWAS P=2.53e-19 · Best GWAS P=4.02e-21 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | GPR126 | 0.06 | 0.04 | lasso | 4 | 0.04 | 0.00061 | -8.9 | 9.0 | 2.5e-19 | -0.98 | 0.02 | 0.96 | TRUE |
| 2 | METSIM | Adipose | GPR126 | 0.05 | 0.01 | blup | 429 | 0.02 | 0.00019 | -5.3 | 6.7 | 2.0e-11 | -0.74 | 0.10 | 0.90 | FALSE |
| 3 | NTR | Blood | HIVEP2 | 0.02 | 0.01 | blup | 424 | 0.01 | 0.00262 | -3.6 | -5.4 | 5.3e-08 | 0.41 | 0.34 | 0.05 | FALSE |
| 4 | The Cancer Genome Atlas | Uterine Corpus Endometrial Carcinoma | NMBR | 0.09 | 0.01 | blup | 46 | 0.04 | 0.03380 | 3.8 | -5.5 | 4.3e-08 | 0.11 | 0.02 | 0.63 | TRUE |