TWAS
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Traits
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Traits
:
Leg fat-free mass (right)
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chr10:120,164,251-121,632,800
Best TWAS P=1.69e-09 · Best GWAS P=9.82e-08 conditioned to 5.65e-05
120.2M
120.4M
120.6M
120.8M
121M
121.2M
121.4M
121.6M
0
2
4
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Esophagus Gastroesophageal Junction
FAM45A
0.24
0.13
enet
51
0.09
0.00027
3.9
6.0
1.7e-09
0.24
0.12
0.10
TRUE
1
GTEx
Breast Mammary Tissue
PRDX3
0.27
0.00
enet
30
0.02
0.03880
3.7
5.2
1.7e-07
0.13
0.10
0.08
FALSE