TWAS hub - PRDX3

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Breast Mammary Tissue	0.2690	0.0770	2.2e-04	0.002	NA	0.018	NA	0.009	2.5e-01	NA	3.9e-02	NA	1.0e-01
2	GTEx	Breast Mammary Tissue (Male)	0.0236	0.0916	4.2e-01	0.011	NA	0.008	NA	-0.013	1.8e-01	NA	2.1e-01	NA	8.7e-01
3	GTEx	Breast Mammary Tissue (Female)	0.3355	0.0925	4.1e-04	0.107	NA	0.120	NA	0.089	4.4e-04	NA	1.9e-04	NA	1.3e-03
4	GTEx	Cells EBV-transformed lymphocytes	0.2680	0.0960	5.8e-03	0.123	NA	0.164	NA	0.138	8.2e-05	NA	5.1e-06	NA	3.1e-05
5	GTEx	Muscle Skeletal	0.1038	0.0380	1.2e-03	0.100	NA	0.089	NA	0.101	5.3e-10	NA	4.6e-09	NA	4.2e-10
6	METSIM	Adipose	0.0674	0.0217	2.8e-05	0.046	0.027	0.041	0.034	0.047	1.7e-07	5.5e-05	7.1e-07	7.2e-06	1.3e-07
7	NTR	Blood	0.0583	0.0144	9.1e-10	0.037	0.031	0.038	0.033	0.042	4.3e-12	2.7e-10	2.8e-12	7.3e-11	1.8e-13
8	ROSMAP	Brain Pre-frontal Cortex	0.1323	0.0416	3.4e-04	0.025	0.021	0.059	0.051	0.047	3.1e-04	7.9e-04	4.4e-08	3.9e-07	9.1e-07
9	YFS	Blood	0.0527	0.0133	1.2e-10	0.032	0.049	0.047	0.048	0.041	7.4e-11	1.2e-15	3.8e-15	2.5e-15	2.6e-13
10	TCGA	Kidney Renal Clear Cell Carcinoma	0.0346	0.0184	1.9e-04	0.026	0.028	0.015	NA	0.015	5.8e-04	3.5e-04	7.3e-03	NA	7.3e-03
11	TCGA	Lung Squamous Cell Carcinoma	0.0259	0.0164	7.9e-03	-0.001	0.007	0.000	NA	0.002	4.9e-01	5.1e-02	3.3e-01	NA	1.9e-01
12	TCGA	Thyroid Carcinoma	0.0620	0.0360	6.5e-05	0.071	0.035	0.044	NA	0.054	1.9e-07	2.0e-04	4.2e-05	NA	5.2e-06

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	3	4	5	6	7	8	9	10	11	12
Pulse wave reflection index	5.3	6.5	13.0	-1.8	-1.8	-3.1	-3.6	-3.3	-1.8	-1.6	-2.7	-2.9	-2.6	-3.2
Smoking status: Current	4.9	7.7	12.7	-2.3	-1.2	-2.7	-3.3	-3.6	-3.5	-3.3	-3.4	-3.0	-2.0	-2.8
Current tobacco smoking	4.6	7.4	12.0	-2.6	-1.3	-2.5	-3.2	-3.4	-3.4	-3.1	-3.5	-2.9	-2.0	-2.7
Serious illness, injury or assault of a close relative in last 2 years	4.3	4.9	9.3	-0.3	0.4	-2.7	-2.8	-2.8	-2.4	-1.4	-2.0	-3.0	-2.6	-2.8
Supplements: Fish oil (including cod liver oil)	4.1	5.4	11.1	-1.7	-1.0	2.7	2.7	2.5	1.8	1.6	3.0	3.3	2.7	2.6
Smoking Status	4.0	9.5	16.2	-2.5	-1.3	-3.0	-3.7	-4.0	-3.8	-3.0	-2.8	-3.7	-3.1	-3.6
Mineral and other dietary supplements	3.6	4.9	11.1	0.7	0.3	-2.5	-2.7	-2.6	-2.3	-0.7	-2.3	-3.3	-2.9	-2.5
Pulse wave peak to peak time	3.5	4.1	7.5	1.3	0.4	2.0	2.7	2.4	1.5	0.4	2.7	2.7	2.5	2.6
Crohns Disease (2012)	3.0	4.9	8.4	-1.1	-0.3	-2.7	-2.9	-2.8	-2.3	-0.8	-2.7	-2.6	-2.3	-2.7
Tinnitus: Yes, but not now, but have in the past	3.0	3.2	7.6	-0.6	-0.3	-1.3	-1.9	-2.1	-2.2	-1.0	-2.8	-2.5	-2.1	-1.9
Height	2.9	56.4	118.8	10.2	10.9	6.9	9.0	8.0	3.1	7.6	2.8	7.4	7.6	8.6
Other serious medical condition/disability diagnosed by doctor	2.8	3.7	6.6	1.4	0.7	-2.1	-2.6	-2.2	-2.6	-0.9	-2.5	-2.0	-1.6	-2.4
Ever unenthusiastic/disinterested for a whole week	2.7	3.2	11.3	-2.1	-3.4	-1.6	-1.9	-1.6	-0.7	-2.0	-0.5	-1.9	-1.8	-1.7
Pulse wave Arterial Stiffness index	2.7	3.1	6.8	-1.0	0.1	-1.8	-2.3	-2.1	-1.4	-0.1	-2.6	-2.4	-2.0	-2.2
Major Depression (MDD)	2.5	3.1	5.7	-1.0	-0.3	-2.1	-2.2	-1.7	-1.5	-1.3	-2.3	-2.3	-2.4	-1.9
Medication: Cholesterol lowering	2.5	4.0	7.6	0.7	0.4	-1.6	-2.6	-2.4	-1.8	-1.9	-2.2	-2.8	-2.4	-2.5
Mother’s age at death	2.5	3.2	10.5	-1.9	-2.0	1.6	1.3	1.8	2.0	0.6	3.2	2.4	1.2	1.1
Taking other prescription medications	2.3	3.5	6.7	-0.0	0.5	-1.9	-2.4	-2.3	-2.6	-2.2	-2.2	-2.0	-1.6	-2.0
Standing height	2.3	22.9	50.7	5.7	7.1	3.8	5.7	4.4	0.9	5.6	2.1	4.9	5.8	5.7
Comparative height size at age 10	2.3	12.9	41.7	5.1	6.5	2.1	3.8	3.4	1.5	2.4	0.8	3.5	4.3	4.1
Ever smoked	2.3	4.0	10.0	0.3	-0.0	-1.9	-2.4	-2.4	-2.3	-0.3	-1.7	-3.2	-2.9	-2.3
Number of children fathered	2.2	2.4	4.7	0.1	0.1	1.5	1.7	1.9	2.2	0.9	2.0	2.2	1.9	1.6
Long-standing illness, disability or infirmity	2.2	3.3	6.5	0.4	0.6	-1.9	-2.2	-2.3	-2.3	-0.8	-2.0	-2.6	-2.4	-2.0
Frequency of tiredness / lethargy in last 2 weeks	2.1	3.4	13.0	1.1	0.2	-0.7	-2.1	-1.7	-0.5	-3.6	-2.7	-1.8	-1.5	-2.2
Medication: Seretide 50 evohaler	2.1	2.4	5.3	0.1	-0.8	-2.3	-1.8	-1.7	-1.3	-2.1	-2.1	-1.4	-1.3	-1.5
Medication: Omeprazole (e.g. Zanprol)	2.1	2.6	6.1	0.7	-0.4	-1.1	-2.3	-1.9	-1.6	-2.5	-1.3	-1.3	-1.3	-2.4
Irritable Bowel Disease (IBD)	2.0	4.8	8.9	-1.2	-0.5	-2.5	-2.8	-2.5	-1.6	-0.2	-2.8	-3.0	-3.0	-2.6
Past tobacco smoking	2.0	3.6	9.8	0.1	-0.1	1.5	2.3	2.4	2.2	0.6	1.0	2.8	3.1	2.5
Birth weight of first child	2.0	3.6	10.5	1.8	1.5	3.2	1.8	2.0	1.7	0.9	2.5	2.6	1.6	1.0
Medication for hormone replacement therapy	1.9	2.1	3.7	0.1	-1.1	1.4	1.5	1.9	1.9	1.9	1.1	1.6	1.7	1.7
Hand grip strength (right)	1.9	5.1	13.5	3.7	2.6	1.6	2.7	2.0	0.1	2.0	1.9	2.2	2.8	2.6
Ever highly irritable/argumentative for 2 days	1.9	2.3	4.8	0.1	-0.8	-2.1	-1.3	-1.8	-2.2	-1.8	-1.7	-2.2	-1.1	-0.8
Crohns Disease (2017)	1.8	3.9	7.2	-2.2	-1.5	-2.3	-2.4	-2.2	-1.3	-0.2	-2.7	-2.5	-2.2	-2.1
Forced expiratory volume in 1-second (FEV1)	1.8	6.0	15.4	-0.2	-0.1	2.0	3.2	1.9	-0.1	3.9	3.8	2.6	2.9	3.2
Medication: Paracetamol	1.8	3.0	15.5	-0.2	-0.4	-1.2	-1.6	-1.9	-1.0	-3.9	-1.8	-1.8	-1.5	-1.6
Medication for cholesterol, blood pressure or diabetes	1.8	3.0	5.2	-1.3	-1.4	1.1	2.3	2.0	1.2	1.9	1.8	2.2	2.2	2.2
Stomach or abdominal pain in last month	1.7	2.1	3.0	-1.5	-1.3	-1.2	-1.7	-1.4	-1.7	-1.4	-1.6	-1.6	-1.7	-1.4
Pulse rate	1.7	2.9	5.4	1.2	1.4	2.3	2.2	2.3	2.1	1.1	1.2	1.9	1.6	1.7
Health satisfaction	1.7	2.2	9.7	-0.4	-0.9	-1.4	-1.4	-0.9	-1.7	0.4	-3.1	-2.2	-1.6	-0.9
Suffer from ‘nerves’	1.7	2.6	6.8	-0.9	-0.8	2.6	1.9	2.1	1.9	-1.6	0.6	1.9	1.7	1.7
Commuting to job workplace: Car/motor vehicle	1.7	1.9	4.5	1.3	1.4	1.3	1.8	1.4	0.2	2.1	0.0	1.2	2.0	1.7
Medication for cholesterol	1.7	2.6	7.4	1.6	2.7	-1.8	-1.6	-2.0	-1.9	-0.8	0.2	-1.3	-1.5	-1.5
Fasting Glucose	1.6	2.0	3.3	-0.7	-1.1	-1.6	-1.8	-1.8	-1.2	-0.6	-1.7	-1.8	-1.4	-1.8
Hypothyroidism (self reported)	1.6	3.8	9.2	-0.0	0.9	-3.0	-2.2	-2.8	-2.7	0.7	-1.9	-2.5	-1.6	-1.6
Hand grip strength (left)	1.6	4.2	8.1	2.8	1.7	1.4	2.6	2.0	1.0	1.7	2.3	2.2	2.6	2.5
Maternal smoking around birth	1.6	2.4	5.6	-1.2	-1.0	-2.0	-2.3	-2.4	-1.9	-1.4	-0.5	-1.0	-0.3	-2.1
Impedance of arm (right)	1.6	7.5	15.4	-0.9	0.5	3.7	3.5	3.3	2.4	2.8	1.0	3.5	3.9	3.3
Medication: Paracetamol	1.6	2.5	11.4	-0.2	-0.5	-1.8	-1.5	-1.9	-1.1	-3.4	-1.4	-1.6	-1.2	-1.3
Ever depressed for a whole week	1.6	1.9	3.4	-1.2	-1.8	-1.8	-1.8	-1.4	-1.1	-1.1	-0.6	-1.8	-1.1	-1.5
Medication: Levothyroxine sodium	1.5	2.6	9.0	-0.2	0.8	-3.0	-1.9	-2.5	-1.9	0.7	-0.6	-2.0	-1.2	-1.2
Headache pain in last month	1.5	2.6	8.9	-1.2	-0.3	-0.8	-1.8	-2.0	-1.4	-3.0	-1.8	-1.7	-1.5	-1.7
Hypothyroidism/myxoedema (self-reported)	1.5	2.9	8.0	-0.1	0.7	-2.8	-2.1	-2.5	-1.8	0.8	-1.3	-2.3	-1.5	-1.4
Age at first live birth	1.5	2.6	9.3	3.1	2.8	-2.0	-0.9	-1.3	-1.4	0.2	-0.8	-1.5	-1.4	-0.9
Medication: Omeprazole	1.5	1.8	3.1	0.7	-0.2	-1.1	-1.8	-1.6	-1.4	-1.7	-1.8	-1.4	-0.9	-1.8
Forced expiratory volume in 1-second (FEV1), predicted	1.5	3.2	8.8	2.1	2.5	1.0	2.2	1.3	-0.5	3.0	0.3	1.2	1.9	2.3
Risk taking	1.5	2.2	6.8	-0.5	-0.3	-1.7	-1.2	-1.7	-2.4	0.2	-2.6	-2.2	-1.0	-0.7
Ulcerative Colitis (UC)	1.4	2.6	5.6	0.1	0.4	-1.8	-2.0	-1.9	-1.4	0.4	-1.9	-2.3	-2.4	-1.9
Forced vital capacity (FVC)	1.4	5.3	11.4	-0.3	0.3	2.2	3.0	1.8	-0.1	3.4	3.4	2.7	3.0	2.9
Impedance of arm (left)	1.4	6.6	12.6	-0.5	-0.1	3.5	3.3	3.2	2.2	2.8	0.8	3.2	3.5	3.0
Overall health rating	1.4	3.0	7.1	-0.3	-0.1	-1.3	-2.1	-1.8	-1.7	-2.7	-2.3	-1.9	-1.8	-2.0
Alcohol drinker status: Never	1.4	1.6	10.2	-0.4	-1.1	-0.6	-1.4	-1.1	-0.4	-3.2	-1.1	-0.8	-0.6	-1.5
Depressed Affect (Nagel 2018)	1.3	2.7	5.0	-1.3	-1.4	-1.5	-1.8	-1.9	-1.4	-2.2	-1.1	-2.2	-2.1	-1.7
Alzheimer’s Disease (in mother)	1.3	1.5	3.2	1.0	1.1	1.4	1.7	1.5	1.3	0.1	-0.3	1.1	1.7	1.8
Coronary Artery Disease (CAD)	1.3	1.6	4.9	0.7	-0.3	-2.2	-1.7	-1.7	-0.9	-0.1	-1.7	-1.7	-0.7	0.0
Bilateral oophorectomy (both ovaries removed)	1.3	1.6	3.2	-1.3	-1.5	1.4	1.2	1.3	0.8	0.6	0.9	1.8	1.8	1.3
Happiness	1.3	1.6	6.3	0.3	0.7	-1.0	-0.7	-1.1	-1.6	0.3	-1.1	-2.2	-2.5	-0.7
Emphysema/chronic bronchitis	1.3	1.4	3.1	0.3	0.9	-1.3	-1.4	-1.1	-1.1	0.6	-1.6	-1.6	-1.7	-1.3
Had major operations	1.3	1.5	3.6	1.0	1.0	-1.6	-1.2	-1.3	-1.0	0.1	-1.6	-1.9	-1.5	-1.1
Wears glasses or contact lenses	1.3	1.5	3.5	-0.7	-1.4	-0.7	-1.6	-1.3	-0.4	-1.9	-0.3	-1.2	-1.6	-1.8
Age started oral contraceptive pill	1.3	1.7	4.2	-0.9	0.0	1.0	1.4	1.6	1.6	0.6	1.7	2.1	1.1	1.5
Lupus	1.2	1.9	5.5	-0.7	0.8	-0.7	-1.4	-1.3	-1.5	-0.4	-1.9	-1.9	-2.4	-1.4
Ulcerative Colitis	1.2	1.7	4.2	-0.5	0.7	-1.5	-1.6	-1.8	-1.6	-0.3	-1.4	-1.7	-2.1	0.0
Ever used hormone-replacement therapy (HRT)	1.2	1.5	8.8	-2.6	-3.0	0.8	-0.0	0.4	0.0	0.3	0.7	0.7	0.4	0.0
Father’s age at death	1.2	1.6	6.3	-1.5	-1.9	1.0	0.1	0.5	1.9	-2.5	-1.1	0.5	0.3	-0.1
Peak expiratory flow (PEF)	1.2	2.8	7.6	0.5	-0.1	1.2	2.5	1.5	-0.0	2.7	1.9	1.4	2.0	2.6
Birth weight	1.2	2.7	6.5	-0.2	-0.4	1.6	1.5	1.9	2.1	-0.4	2.3	2.5	2.3	1.5
Number of full sisters	1.2	1.5	5.8	1.2	1.6	0.9	1.4	1.3	0.6	2.4	-0.7	-0.2	0.4	1.4
Smoking status: Previous	1.2	1.9	7.1	0.1	-0.1	-0.8	-1.6	-1.5	-1.3	0.1	-0.2	-2.0	-2.7	-2.0
Financial situation satisfaction	1.2	1.5	6.2	-0.0	0.8	-1.5	-0.6	-1.3	-1.7	0.3	-0.8	-2.5	-1.7	-0.5
Tinnitus: Yes, now most or all of the time	1.2	1.3	4.3	0.5	0.0	-1.5	-0.9	-0.9	-1.5	0.7	-0.4	-2.0	-2.1	-0.9
Average weekly beer plus cider intake	1.2	1.7	2.7	0.6	0.9	-1.1	-1.4	-1.2	-1.6	-1.6	-1.6	-1.5	-1.5	-1.6
Impedance of whole body	1.2	6.0	13.2	-1.9	-1.0	3.4	3.0	2.8	2.0	1.9	0.5	3.2	3.6	2.7
Chronotype (morning person)	1.1	2.5	7.0	0.2	-0.6	1.6	1.6	1.7	2.1	2.6	1.9	1.6	1.1	1.6
Alcohol usually taken with meals	1.1	1.7	3.7	-0.6	-0.4	1.5	1.4	1.2	0.9	1.0	1.9	1.9	1.9	1.3
Nervous feelings	1.1	2.0	5.5	0.6	0.5	1.7	1.1	1.5	1.4	-1.2	1.9	2.3	1.8	1.1
Hayfever/allergic rhinitis (self-reported)	1.1	1.4	3.5	0.2	-0.5	1.2	1.7	1.7	1.0	1.1	0.7	1.1	1.3	1.9
Trunk fat-free mass	1.1	6.1	27.1	5.1	5.2	-0.2	1.7	1.0	-0.9	2.5	1.2	1.0	1.3	2.1
Forced expiratory volume in 1-second (FEV1), Best measure	1.1	3.4	9.4	-0.1	-0.4	2.0	2.6	1.5	0.0	2.6	3.1	1.9	1.8	2.4
Reason for reducing amount of alcohol drunk: Health precaution	1.1	1.3	4.0	0.4	-0.2	-0.8	-1.4	-1.3	-1.1	0.8	0.0	-1.7	-2.0	-1.6
Medication for pain relief, constipation, heartburn	1.1	1.9	6.4	-0.6	0.4	0.4	1.1	1.3	2.0	2.5	1.8	1.4	1.6	1.0
Diabetes diagnosed by doctor	1.1	1.8	3.1	0.9	1.0	-1.4	-1.4	-1.5	-1.5	-1.7	-1.2	-1.8	-1.6	-1.2
Osteoporosis (self-reported)	1.1	1.4	4.2	-0.2	-0.4	1.9	1.5	1.7	2.1	0.6	1.0	0.9	-0.0	1.3
Number of self-reported non-cancer illnesses	1.1	1.9	3.6	-0.3	-1.0	-1.1	-1.9	-1.7	-1.9	-1.3	-1.3	-1.6	-1.4	-1.7
Ever taken oral contraceptive pill	1.1	1.2	2.0	-1.2	-1.4	-1.1	-1.2	-1.4	-0.7	-0.4	-1.2	-1.3	-1.2	-1.2
Neuroticism (2016)	1.0	1.4	4.0	-1.0	-0.7	-0.8	-1.0	-1.0	-0.7	-1.9	-1.2	-1.6	-2.0	-0.7
Medication: Metformin	1.0	1.4	3.3	-0.2	-0.4	-1.3	-1.4	-1.4	-1.0	-1.5	-1.8	-1.5	-1.1	-1.0
Severe depression (siblings)	1.0	1.1	8.5	-1.6	-2.9	-0.0	0.6	0.6	-0.5	0.1	-0.3	0.2	0.3	1.0
Leg fat-free mass (left)	1.0	5.3	28.2	5.3	4.8	0.1	1.4	0.8	-0.6	2.0	1.3	0.6	0.7	1.6
Townsend deprivation index at recruitment	1.0	1.4	3.7	0.2	-0.0	-1.3	-1.1	-1.5	-1.9	-1.4	-1.6	-1.2	-0.8	-0.9
Supplements: Glucosamine	1.0	1.3	2.4	0.0	0.2	0.9	1.6	1.1	1.1	1.5	1.4	1.1	1.3	1.6
Leg predicted mass (left)	1.0	5.3	28.7	5.4	4.9	0.0	1.4	0.8	-0.6	1.8	1.3	0.6	0.6	1.6
Medication: Ramipril	1.0	1.3	5.0	2.2	1.8	0.4	-0.4	-0.1	0.6	-2.0	-1.3	-0.3	-0.3	-0.6
Number of live births	1.0	1.4	3.2	0.4	1.1	1.8	1.6	1.8	1.7	0.1	0.2	0.9	0.9	1.6
Noisy workplace	1.0	1.2	3.0	1.3	-0.6	-0.6	-1.5	-1.3	-0.5	-0.6	0.1	-1.5	-1.7	-1.7
Trunk predicted mass	1.0	5.8	26.2	5.0	5.1	-0.2	1.7	1.0	-0.9	2.4	1.1	0.9	1.3	2.0
Medication: Ibuprofen	1.0	1.2	4.4	-1.4	-2.1	-0.9	-0.2	-1.1	-2.0	0.1	-0.0	-0.8	-1.0	-0.1
Age at last live birth	1.0	1.4	8.4	2.9	2.1	-0.6	-0.2	-0.3	-0.6	-0.1	0.2	-0.9	-1.3	-0.4
Whole body fat-free mass	1.0	5.9	28.5	5.3	5.2	-0.2	1.6	0.9	-0.9	2.1	1.2	0.7	1.0	1.9
Whole body water mass	1.0	5.8	28.1	5.3	5.3	-0.2	1.6	0.9	-0.8	2.1	1.1	0.7	0.9	1.9
Leg predicted mass (right)	1.0	5.1	28.5	5.3	5.0	-0.3	1.1	0.5	-0.7	1.4	1.1	0.4	0.6	1.4
Commuting to job workplace: Public transport	1.0	1.2	2.1	-1.3	-1.4	-1.2	-1.4	-1.4	-1.1	0.4	-0.1	-1.0	-1.1	-1.4
Basal metabolic rate	1.0	5.3	25.8	5.1	4.8	-0.1	1.7	1.0	-0.7	1.8	1.3	0.8	1.0	2.0
Diabetes (father)	0.9	1.2	2.3	0.4	-0.0	1.1	1.4	1.4	1.3	1.3	0.4	1.0	1.3	1.5
Impedance of leg (right)	0.9	4.5	8.3	-2.9	-2.1	2.7	2.6	2.2	1.2	1.8	-0.4	2.2	2.7	2.3
Age when periods started (menarche)	0.9	2.2	7.4	-2.4	-2.4	1.7	0.8	0.9	1.4	0.8	2.7	0.8	-0.5	0.4
Medication: Atenolol	0.9	1.1	5.3	-0.6	-0.7	-1.1	-1.1	-0.6	-0.5	-0.2	-2.3	-1.2	-1.2	-0.8
Number of incorrect matches in round	0.9	1.4	2.9	-0.5	-0.2	-1.5	-1.7	-1.7	-1.2	-1.6	0.1	-1.0	-1.0	-1.7
Forced vital capacity (FVC), Best measure	0.9	3.2	6.5	0.3	0.3	2.0	2.4	1.4	-0.1	2.2	2.5	2.1	2.2	2.3
Comparative body size at age 10	0.9	2.5	7.6	-1.4	-0.3	-1.2	-1.9	-1.4	1.0	-2.8	1.1	-1.4	-2.5	-1.9
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.9	1.1	3.3	-0.8	-0.6	-0.2	-0.8	-0.8	-0.9	0.8	-1.5	-1.8	-1.8	-0.9
Leg fat-free mass (right)	0.9	4.9	27.4	5.2	4.9	-0.4	1.1	0.5	-0.7	1.4	1.1	0.4	0.6	1.4
Handedness (chirality/laterality): Left-handed	0.9	1.1	4.0	1.7	2.0	-0.1	0.0	-0.1	-1.2	1.0	-1.9	-0.7	0.1	0.1
Mood swings	0.9	1.5	5.5	-1.5	-1.2	-1.1	-1.4	-1.3	-0.9	-2.4	-0.2	-1.0	-1.0	-1.4
Loneliness, isolation	0.9	1.3	5.9	-0.6	-1.0	-1.0	-1.1	-1.3	-1.0	-2.4	-1.0	-1.0	-0.5	-0.9
Friendships satisfaction	0.9	1.1	3.6	1.9	0.9	-1.4	-0.1	-0.6	-1.0	-0.4	-1.3	-1.6	-1.2	0.1
Qualifications: nursing, teaching	0.9	1.4	3.4	-1.1	-1.0	-1.6	-1.2	-1.6	-1.8	-0.8	-1.1	-1.2	-0.6	-0.9
Medication: Aspirin	0.9	1.2	4.6	-0.2	0.4	-0.5	-0.9	-0.8	-0.8	-1.3	-2.1	-1.4	-1.4	-1.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.9	1.8	10.8	-1.8	-2.1	1.1	0.6	0.1	0.2	0.1	3.3	1.2	0.3	0.3
Unable to work because of sickness or disability	0.9	1.1	3.6	0.8	0.6	-1.1	-0.6	-1.3	-1.9	-0.4	-1.5	-1.5	-1.0	-0.4
Depression (Nagel 2018)	0.8	1.2	5.2	0.3	-1.0	-0.3	-0.8	-0.7	-0.0	-2.3	-1.2	-1.6	-1.3	-1.1
Worry (Nagel 2018)	0.8	1.6	8.4	-1.7	-1.9	1.2	0.2	0.5	1.5	-2.9	0.0	0.7	0.5	0.1
Verbal and Numeric Reasoning (VNR)	0.8	1.8	4.4	-1.4	-1.4	-0.5	-1.9	-1.4	-0.3	-2.1	-0.9	-0.8	-1.4	-2.1
Waist Hip Ratio (WHR)	0.8	3.5	9.4	0.3	1.5	1.8	2.5	2.4	1.3	-0.3	-0.9	2.3	3.1	2.7
Type 2 Diabetes (T2D) (2018)	0.8	1.4	3.2	1.1	0.8	-1.1	-0.9	-1.1	-1.3	-1.6	-1.0	-1.8	-1.8	-0.7
Medication: Co-codamol	0.8	0.9	2.2	0.4	0.3	0.8	1.1	1.2	0.9	1.5	0.4	0.6	1.2	1.4
Diverticular disease/diverticulitis (self-reported)	0.8	0.9	3.0	-1.7	-1.1	-0.3	-1.3	-1.1	-0.2	-1.3	0.4	0.5	-0.3	-1.4
Sitting height	0.8	5.8	13.9	3.4	3.7	1.6	2.4	1.9	0.7	3.5	1.9	2.2	2.3	2.5
Had menopause	0.8	1.0	3.6	-0.2	-1.3	-0.9	-1.1	-0.5	-0.1	-1.9	0.3	-0.7	-1.6	-1.2
Diabetes (self-reported)	0.8	1.2	4.1	0.0	0.6	-0.8	-1.1	-1.3	-1.2	-2.0	-1.1	-1.4	-1.0	-1.0
Ever had bowel cancer screening	0.8	0.9	4.0	-2.0	-0.5	0.2	-1.0	-1.1	0.5	-1.1	-0.2	-0.5	-0.4	-1.4
Mouth/teeth dental problems: Mouth ulcers	0.8	1.2	2.3	1.3	1.3	-0.8	-1.2	-1.1	-1.1	0.4	-0.9	-1.3	-1.5	-1.4
Osteoarthritis (self-reported)	0.8	1.0	2.2	-1.0	-1.2	1.3	1.2	1.5	1.1	0.2	0.3	0.9	0.9	1.2
Miserableness	0.8	1.3	2.9	-1.2	-0.8	-1.1	-1.2	-1.2	-1.7	0.0	-1.2	-1.6	-1.4	-0.9
Medication: Lisinopril	0.8	1.1	4.1	-2.0	-2.0	-0.5	-0.6	-0.3	-0.6	0.6	-1.6	-0.7	-0.6	-0.4
Commuting to job workplace: Cycle	0.8	0.9	2.2	0.3	0.2	0.6	1.3	1.1	1.4	0.9	0.8	0.9	1.5	1.2
Neuroticism (Nagel 2018)	0.7	1.7	6.9	-2.3	-2.6	0.2	-0.6	-0.2	0.5	-2.5	-0.4	-0.7	-0.9	-0.5
Bipolar Disorder (2011)	0.7	0.7	1.8	0.5	0.4	1.2	1.3	1.3	1.1	1.0	-0.5	0.0	0.0	0.0
HbA1C	0.7	0.8	2.6	-0.2	0.1	-1.3	-1.3	-1.1	-0.5	-0.8	-1.6	-0.9	-0.3	-0.7
HDL Cholesterol	0.7	1.2	4.0	-1.3	-0.5	-0.8	-1.0	-1.2	-1.1	0.3	-2.0	-1.4	-0.9	-1.0
Respiratory disease	0.7	1.6	3.5	-0.2	-0.2	-1.6	-1.7	-1.3	-1.2	-1.2	-1.9	-1.2	-1.2	-1.4
Frequency of depressed mood in last 2 weeks	0.7	1.0	4.1	-0.3	-1.1	-0.5	-0.9	-1.0	-0.3	-2.0	-1.0	-1.5	-0.8	-1.0
Relative age of first facial hair	0.7	1.5	4.2	-1.7	-0.9	2.1	1.4	0.8	0.4	1.4	1.3	1.2	1.0	1.1
Average weekly fortified wine intake	0.7	0.8	2.1	-1.1	-0.8	0.8	1.0	1.3	1.5	0.3	0.7	0.8	0.4	1.0
Impedance of leg (left)	0.7	3.3	9.8	-3.1	-2.1	2.0	1.9	1.5	0.9	0.5	-0.2	2.0	2.7	1.8
Weight	0.7	3.4	17.1	4.1	3.6	0.4	1.5	1.2	-0.1	0.5	1.4	0.9	0.9	1.7
Mouth/teeth dental problems: Dentures	0.7	1.1	5.9	0.1	-0.0	1.5	0.4	1.2	2.4	-0.3	1.0	1.4	0.9	0.3
Medication: Ibuprofen (e.g. Nurofen)	0.7	0.9	4.2	-1.0	-1.5	-0.4	0.0	-0.8	-2.1	-0.1	-0.6	-0.8	-0.9	0.2
Depression (self-reported)	0.7	0.8	4.3	-2.1	-1.5	-0.9	-0.1	-0.1	-0.6	-0.8	0.9	0.1	0.6	0.4
Exposure to tobacco smoke at home	0.7	0.8	1.8	0.3	0.1	1.3	0.8	1.2	1.4	-1.3	0.5	0.9	0.6	0.7
Worry too long after embarrassment	0.7	1.1	3.2	0.1	-0.2	1.8	1.0	1.5	1.8	0.1	1.3	1.1	0.4	0.9
Heart disease (mother)	0.7	0.8	3.6	0.5	0.7	-0.2	-1.1	-0.6	-0.5	0.0	-1.9	-0.9	-1.1	-1.2
Arm predicted mass (right)	0.7	3.5	18.7	4.3	4.1	-0.7	0.9	0.3	-1.3	1.1	0.6	0.1	0.3	1.2
Illness, injury, bereavement, stress in last 2 years	0.7	0.8	5.1	2.3	1.9	0.2	0.5	0.3	0.6	-0.4	0.2	0.2	0.3	0.5
Ever had stillbirth, spontaneous miscarriage or termination	0.7	0.8	4.3	-0.8	-0.7	-0.8	-0.4	-0.6	-1.1	-0.2	-2.1	-1.2	-0.6	-0.4
Illnesses of father: None of the above (group 1)	0.7	0.9	2.6	-0.5	0.1	-0.7	-1.0	-1.1	-0.5	-1.4	0.3	-1.0	-1.6	-1.2
Pain type(s) experienced in last month: Hip pain	0.7	0.9	3.0	0.1	-0.3	1.2	1.7	1.1	0.3	0.8	-0.5	0.5	1.1	1.6
Medication: Bendroflumethiazide	0.7	1.1	3.8	-1.2	-0.4	1.3	1.2	1.2	0.8	2.0	0.1	0.5	0.4	1.3
Arm fat-free mass (left)	0.7	3.3	17.1	4.1	4.0	-0.5	1.1	0.5	-1.0	0.9	0.8	0.4	0.5	1.4
Fractured/broken bones in last 5 years	0.7	0.9	2.3	-1.4	-1.2	-0.6	-0.1	-0.6	-1.5	1.3	-0.9	-1.1	-0.8	-0.0
Arm predicted mass (left)	0.7	3.3	15.7	3.8	4.0	-0.1	1.4	0.8	-0.7	1.1	1.2	0.7	0.9	1.6
Schizophrenia vs Biploar Disorder	0.6	0.8	1.6	-1.1	-0.9	1.3	1.2	0.9	1.1	0.7	0.4	0.7	0.9	1.1
Ovarian Cancer	0.6	0.8	3.1	0.8	1.1	-1.3	-0.7	-0.9	-1.8	0.4	-0.5	-0.9	-0.6	-0.8
Rheumatoid Arthritis	0.6	0.8	4.6	-0.5	-1.8	0.5	-0.2	-0.1	0.2	-0.5	2.1	0.9	0.1	-0.5
Triglycerides	0.6	0.9	1.9	-1.3	-1.3	-0.7	-1.3	-0.9	-0.7	-1.4	-0.7	-0.6	-0.7	-0.8
Average weekly spirits intake	0.6	0.7	4.4	-2.1	-1.1	0.5	0.1	0.0	0.4	-0.3	1.1	0.7	0.6	0.3
Hearing difficulty/problems: Yes	0.6	0.9	2.7	0.5	-0.2	0.4	-0.8	-0.5	0.3	-1.6	-1.6	-1.1	-1.2	-1.3
Systolic blood pressure, automated reading	0.6	1.6	3.5	-0.9	-0.3	1.9	1.6	1.4	1.4	-0.1	1.5	1.6	1.2	1.6
Eye problems/disorders: Diabetes related eye disease	0.6	0.7	2.8	0.2	-1.0	-0.8	-0.8	-0.6	-0.9	0.4	-1.7	-1.0	-0.7	-0.5
Fed-up feelings	0.6	1.1	3.5	0.3	-0.9	-0.7	-1.2	-1.2	-1.2	-1.9	-0.7	-1.3	-1.0	-1.2
Hearing difficulty/problems with background noise	0.6	1.0	3.8	0.4	-0.1	0.0	-1.2	-0.6	-0.9	-1.6	-2.0	-0.7	-0.6	-1.5
Time employed in main current job	0.6	0.7	2.3	1.5	1.0	-1.0	-0.2	-0.6	-1.2	-1.4	0.4	-0.0	0.2	-0.0
Prospective memory result	0.6	0.8	2.2	-1.2	-1.4	0.0	-0.9	-0.6	-0.1	-1.5	-0.9	-0.2	-0.4	-1.2
Seen doctor (GP) for nerves, anxiety, tension or depression	0.6	0.9	3.1	-1.8	-1.6	0.3	0.2	0.1	0.0	-1.7	1.2	0.7	0.8	0.3
Medication: Ventolin 100micrograms inhaler	0.6	0.8	3.3	1.3	1.4	-0.7	-0.4	-0.5	-0.8	-0.2	-1.8	0.1	0.8	-0.1
Arm fat-free mass (right)	0.6	3.3	18.1	4.3	4.0	-0.7	0.9	0.2	-1.3	1.1	0.5	0.0	0.3	1.2
Wheeze or whistling in the chest in last year	0.6	1.1	5.4	-0.5	0.4	-0.9	-0.8	-0.7	-0.4	-2.3	-2.2	-0.2	1.0	-0.2
Shortness of breath walking on level ground	0.6	0.7	2.7	1.2	0.8	-0.7	-0.9	-0.4	0.6	-0.9	-1.6	-0.6	-0.0	-0.5
Mouth/teeth dental problems: Loose teeth	0.6	0.7	2.0	0.3	0.7	-0.6	-0.6	-0.9	-0.6	-1.1	-1.4	-1.0	-0.8	-0.7
Neck or shoulder pain in last month	0.6	0.8	2.6	-0.3	-0.0	-0.3	-0.8	-1.0	-0.6	-1.6	-1.2	-1.3	-1.0	-0.6
Medication: Blood pressure	0.6	1.0	3.3	1.1	1.8	-0.4	-1.0	-0.9	-0.5	-0.8	-1.1	-1.2	-1.3	-1.0
Qualifications: NVQ or HND or HNC or equivalent	0.6	0.8	3.1	-1.8	-1.6	-0.9	-0.4	-0.6	-1.0	0.2	0.0	-0.8	-0.8	-0.2
Medication: Aspirin	0.6	0.7	3.2	-0.4	-0.2	-0.1	-0.6	-0.6	-0.9	-0.9	-1.8	-1.1	-1.1	-0.7
Back pain experienced in last month	0.6	0.9	3.5	-0.0	-0.7	-0.3	-1.0	-1.0	-1.0	-0.5	-1.9	-1.3	-0.9	-0.8
Medication: Gliclazide	0.6	0.6	1.6	0.4	0.5	-1.1	-1.0	-1.1	-0.3	0.1	-1.0	-1.2	-0.9	-0.7
Medication: Blood pressure	0.6	1.2	6.4	-1.8	-1.9	0.0	-0.3	-0.0	0.0	-0.4	-2.5	-1.0	-0.4	-0.2
Number of operations (self-reported)	0.6	0.8	2.2	1.5	1.0	-0.1	-1.0	-0.5	-0.3	-0.8	-1.4	-0.7	-1.1	-1.1
Irritability	0.6	1.1	3.5	-1.4	-1.7	1.2	0.2	0.7	1.6	-1.9	0.5	0.2	-0.0	-0.2
Deep venous thrombosis (DVT) (self-reported)	0.6	0.7	2.1	0.9	0.4	-1.4	-0.5	-0.9	-1.5	-0.5	-1.4	-0.8	-0.3	-0.2
Heart disease (siblings)	0.6	0.7	3.4	-0.5	-0.6	0.5	1.1	0.9	1.1	1.9	0.5	0.2	0.4	0.9
Alzheimer’s Disease (including proxy)	0.5	0.8	1.4	0.8	1.0	1.2	1.0	1.0	0.9	-0.4	-0.9	0.4	1.1	1.1
Ever had hysterectomy (womb removed)	0.5	0.6	2.1	-1.4	-0.5	-1.0	-0.5	-0.6	0.1	-1.0	-1.1	-0.6	-0.4	-0.5
Relative age voice broke	0.5	0.7	4.0	-2.0	-0.7	0.6	-0.2	0.0	0.9	1.3	0.9	0.7	0.3	-0.1
Qualifications: CSEs or equivalent	0.5	0.7	1.8	-1.1	0.5	0.4	0.9	0.7	0.3	1.3	1.3	0.7	0.2	1.0
Trunk fat mass	0.5	2.1	9.5	3.1	2.6	0.9	1.4	1.2	0.3	-0.2	1.4	0.9	0.7	1.4
Waist circumference	0.5	1.7	8.1	2.8	2.8	-0.4	0.4	0.5	-0.1	-1.7	0.2	0.3	0.3	0.7
Had other major operations	0.5	0.6	4.8	0.4	1.0	-0.1	-0.2	-0.3	-0.6	-0.1	-2.2	-0.2	0.1	-0.1
Financial difficulties in last 2 years	0.5	0.7	2.8	-1.6	-1.7	-0.6	-0.4	-0.4	-0.6	-0.4	-1.1	-0.7	-0.4	-0.3
Mouth/teeth dental problems	0.5	0.8	2.0	-1.1	-1.4	-1.3	-0.6	-0.9	-1.4	0.3	-0.8	-0.8	-0.1	-0.6
Medication: Simvastatin	0.5	0.7	2.2	-0.1	-1.0	-0.4	-1.1	-0.7	-0.5	-0.6	-1.5	-0.7	-0.5	-1.1
Hair/balding pattern: Pattern 3	0.5	0.8	3.9	0.0	-0.9	-2.0	-1.0	-0.8	-1.4	-0.2	0.9	-0.1	-0.3	-0.5
Illnesses of mother	0.5	0.6	1.4	-0.9	-0.2	-1.2	-0.6	-0.8	-0.7	-0.6	-0.6	-1.0	-1.1	-0.5
Hair/balding pattern: Pattern 4	0.5	1.2	4.5	1.6	2.1	0.6	0.1	0.2	0.2	1.9	-0.6	-1.1	-1.2	-0.2
Loud music exposure frequency	0.5	0.5	2.0	-0.2	-1.4	-0.4	-0.5	-0.3	-0.6	-0.6	-0.6	-1.1	-1.1	-0.7
Chronic bronchitis/emphysema (mother)	0.5	0.6	4.0	0.3	-0.9	1.1	0.6	0.0	0.2	0.5	2.0	0.4	0.2	0.2
Migraine (self-reported)	0.5	0.6	2.4	-1.5	-0.8	0.8	0.9	0.3	-0.5	0.2	-0.3	0.4	0.8	1.1
Alcohol intake frequency.	0.5	1.3	5.3	2.3	0.8	0.5	0.5	1.1	1.7	-1.7	-0.2	0.7	1.0	0.3
Breast cancer (self-reported)	0.5	0.6	2.0	0.5	0.8	1.4	0.9	1.2	0.3	0.2	0.2	1.2	0.5	0.8
High cholesterol (Self-reported)	0.5	0.8	2.5	0.5	0.0	0.0	-0.8	-0.4	-0.2	-1.5	-1.6	-1.2	-1.4	-0.8
Leg fat percentage (left)	0.5	1.7	9.0	0.3	-1.0	-1.2	-1.3	-1.2	-0.8	-3.0	-0.0	-1.3	-1.5	-1.2
Cholesterol lowering medication	0.5	0.8	2.6	-0.9	-1.6	0.6	1.1	1.2	0.5	0.2	-0.8	0.5	0.6	1.1
Alcohol drinker status: Previous	0.5	0.6	3.5	1.9	0.4	0.1	0.1	0.6	1.7	-0.1	-0.5	-0.3	0.3	0.1
Bipolar Disorder or Schizophrenia	0.4	0.9	2.3	1.1	-0.4	1.3	1.1	1.5	1.0	-0.1	-0.6	0.5	1.0	1.0
Reaction Time	0.4	0.7	2.9	1.0	1.7	-0.5	-0.8	-0.6	-0.7	-1.1	-0.8	-0.1	-0.4	-0.6
Breast Cancer	0.4	1.0	2.7	-1.5	-1.3	-0.4	-0.7	-0.5	-0.0	-1.7	1.6	1.0	0.1	-0.9
Mean Putamen Volume	0.4	0.4	2.3	0.0	-0.1	0.5	0.7	0.7	0.6	1.5	0.7	0.4	0.2	0.6
LDL Cholesterol	0.4	0.6	1.5	-0.2	-0.3	-0.9	-1.2	-0.9	-0.1	-1.1	-1.0	-0.7	-0.3	-0.9
BMI	0.4	2.2	12.0	1.8	1.3	-1.3	-1.2	-1.1	-0.4	-3.5	1.6	-0.7	-1.3	-1.0
Vitamin and mineral supplements	0.4	0.5	1.4	0.3	1.2	0.5	0.2	0.5	1.1	-0.9	-0.6	-1.0	-1.1	-0.0
Supplements: Zinc	0.4	0.5	1.2	-0.2	0.7	0.1	-0.7	-0.8	-0.2	-1.1	-1.0	-0.4	-0.5	-1.1
Diabetes (mother)	0.4	0.5	1.3	0.4	-0.2	0.9	0.8	0.8	1.0	0.4	-0.4	1.0	1.1	0.7
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.6	2.9	-0.3	-0.8	1.7	0.8	0.6	0.9	-0.6	-0.3	0.5	0.7	0.5
Neuroticism score	0.4	0.8	6.4	-1.0	-1.2	0.3	-0.4	-0.0	0.3	-2.5	-0.3	-0.3	-0.4	-0.4
Worrier / anxious feelings	0.4	0.7	2.5	-1.0	-0.5	-0.1	-0.8	0.0	0.7	-1.5	-1.6	-0.7	-0.7	-0.5
Qualifications: A levels/AS levels or equivalent	0.4	0.9	3.7	-1.2	-0.4	-1.2	-0.6	-1.2	-1.1	-0.9	-1.9	-0.5	0.0	-0.6
Medication: Lansoprazole	0.4	0.4	1.1	-1.0	-0.2	-0.6	-0.4	-0.3	-0.4	-0.7	1.1	-0.5	-1.1	-0.3
Lung cancer (father)	0.4	0.5	3.3	-0.4	0.2	0.4	-0.1	-0.7	-0.2	-1.1	1.8	0.1	-0.5	-0.5
Length of working week for main job	0.4	0.4	1.3	0.6	1.1	0.2	0.6	0.5	0.4	1.0	-0.5	0.4	0.7	0.6
Blood clot in the leg (DVT)	0.4	0.5	1.6	1.0	0.4	-1.0	-0.2	-0.7	-1.2	-0.4	-1.3	-0.5	-0.0	-0.0
Whole body fat mass	0.4	1.5	8.3	2.9	2.2	0.6	1.0	0.9	0.2	-0.4	1.1	0.4	0.0	1.0
Chest pain or discomfort	0.4	0.6	4.3	-0.2	0.6	-0.4	-0.0	-0.3	-0.2	-1.0	-2.1	-1.0	-0.5	0.2
Family relationship satisfaction	0.4	0.5	1.5	0.5	-0.4	0.8	1.1	1.2	0.4	0.0	0.9	0.4	0.2	1.0
Supplements: Vitamin C	0.4	0.5	2.6	-0.4	-1.6	-0.2	-0.5	-0.8	-0.9	-0.6	0.5	0.2	-0.2	-0.5
Illnesses of father: Heart disease	0.4	0.6	3.3	0.8	0.6	-0.1	0.4	-0.1	-1.1	1.8	-1.0	-0.2	0.7	0.4
Commuting to job workplace: Walk	0.4	0.4	1.5	0.0	0.7	-1.2	-0.1	-0.5	0.5	-1.2	0.5	-0.6	-0.6	-0.0
Guilty feelings	0.4	0.6	1.8	0.4	-1.0	0.4	0.8	1.0	0.2	0.5	0.6	0.8	1.2	1.3
Eye problems/disorders: Glaucoma	0.4	0.5	2.9	-0.8	-1.0	0.1	-0.2	-0.1	0.0	-0.4	-1.7	-0.7	0.1	-0.2
Ever had prostate specific antigen (PSA) test	0.4	0.5	1.8	0.8	0.2	0.6	0.3	0.3	1.0	0.8	0.5	0.9	1.4	0.2
Bipolar Disorder (2018)	0.3	0.5	1.7	1.3	0.6	0.8	0.5	1.1	0.9	-0.7	-0.9	0.2	0.4	0.5
Schizophrenia (2018)	0.3	0.6	1.2	0.4	-1.0	1.1	1.0	1.1	0.6	0.4	-0.1	0.4	0.9	0.9
Prostate Cancer	0.3	0.4	1.1	0.3	1.1	-0.9	-0.7	-0.5	0.3	0.8	-0.5	-0.5	-0.8	-0.6
Body Mass Index (BMI) (2010)	0.3	0.4	1.8	0.9	0.9	0.4	0.4	0.5	0.9	-0.3	1.3	0.6	-0.1	0.1
Primary Biliary Cirrhosis	0.3	0.5	3.7	0.8	1.9	0.3	0.5	0.4	-0.6	-0.1	-0.4	-0.2	-0.4	0.3
Schizophrenia (2014)	0.3	0.6	1.4	0.1	-1.2	1.2	0.9	1.2	0.6	0.2	-0.6	0.3	0.9	0.8
Type 2 Diabetes (T2D) (2012)	0.3	0.4	1.3	0.5	1.2	0.3	0.5	0.8	0.8	0.4	-1.0	-0.1	0.2	0.4
Blood White Count	0.3	2.2	7.8	-0.6	-0.8	-1.3	-2.0	-1.9	-0.8	-1.2	2.8	-0.5	-1.2	-1.9
Allergy or Eczema	0.3	0.8	4.6	2.2	1.2	-0.8	-0.3	-0.3	-0.4	1.4	-0.4	-0.5	-0.1	0.1
Cardiovascular Disease	0.3	1.0	4.2	-0.0	-0.8	0.1	-1.0	-0.9	-0.7	-0.3	-2.1	-1.6	-1.3	-0.8
Lung FVC	0.3	1.4	7.7	-2.6	-2.8	0.5	-0.0	-0.4	0.1	-0.3	1.6	0.0	-0.0	-0.2
Neuroticism	0.3	0.8	5.6	-1.1	-1.4	0.1	-0.1	-0.0	0.5	-2.4	-0.6	-0.3	-0.1	-0.0
Number of treatments/medications taken	0.3	0.6	4.0	-0.2	-1.2	0.0	-0.8	-0.1	0.2	-2.0	0.1	0.4	-0.0	-0.5
Trunk fat percentage	0.3	1.1	2.9	1.7	1.2	1.2	1.3	1.2	0.7	-0.6	1.3	0.9	0.5	1.1
Frequency of unenthusiasm / disinterest in last 2 weeks	0.3	0.4	1.4	0.8	-0.3	0.8	0.0	0.2	0.5	-1.2	-0.8	-0.7	-0.6	-0.3
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.7	2.5	1.3	-0.2	-1.4	-0.8	-0.9	-1.6	-0.3	0.3	-0.6	-0.4	-0.4
Multivitamins +/- minerals	0.3	0.4	1.8	0.7	0.1	-0.4	0.3	-0.0	-0.3	1.0	-0.3	0.5	1.3	0.7
Chronic bronchitis/emphysema (father)	0.3	0.4	2.8	-0.8	-1.7	-0.1	0.1	0.2	0.4	0.6	-0.1	-0.5	-0.2	0.4
Body mass index (BMI)	0.3	1.4	4.0	1.8	0.6	-1.3	-1.0	-0.8	-0.4	-2.0	0.6	-1.3	-1.9	-0.9
Qualifications: None of the above	0.3	0.7	2.8	0.0	-0.2	1.3	0.3	0.8	1.4	-1.7	0.6	0.9	0.6	-0.1
Heart attack	0.3	0.4	1.4	0.7	0.8	0.2	-0.0	0.1	-0.0	-0.8	-1.2	-0.9	-0.9	-0.1
Hip circumference	0.3	1.4	8.1	2.8	2.5	-0.3	0.3	0.3	-0.1	-0.2	1.0	0.3	0.1	0.5
Alcohol intake versus 10 years previously	0.3	0.4	1.3	0.3	1.2	0.4	0.4	1.0	0.4	0.8	0.5	0.9	0.4	0.5
Falls in the last year	0.3	0.4	2.6	0.2	0.4	-0.2	-0.2	-0.4	-1.6	0.2	-0.1	-0.8	-0.7	-0.0
Arm fat mass (right)	0.3	1.0	6.4	2.5	1.7	-0.2	0.4	0.5	-0.0	-0.7	1.1	-0.2	-0.7	0.5
Tense / ‘highly strung’	0.3	0.5	3.7	-0.2	-0.1	0.8	0.2	0.2	0.4	-1.9	-0.1	0.6	0.7	0.1
Qualifications: O levels/GCSEs or equivalent	0.3	0.5	1.1	-0.9	-0.6	-1.0	-1.0	-0.7	-0.7	-0.3	-0.9	-0.4	-0.6	-1.0
Mouth/teeth dental problems: Bleeding gums	0.3	0.4	1.2	0.5	1.1	0.6	0.6	0.4	0.1	-0.7	0.9	0.0	-0.9	0.6
Leg fat percentage (right)	0.3	1.0	4.8	0.4	-0.9	-0.8	-0.9	-0.8	-0.6	-2.2	-0.1	-1.2	-1.5	-0.9
Eye problems/disorders: None of the above	0.3	0.3	1.1	-0.0	0.6	-0.6	-0.4	-0.6	-0.1	-1.0	0.7	-0.5	-0.6	-0.5
Mean time to correctly identify matches	0.3	0.6	2.5	0.5	1.6	-0.5	-0.9	-0.6	-0.4	-0.9	-0.8	-0.4	-0.8	-0.9
Hypertension (Self-reported)	0.3	0.7	3.4	0.5	0.5	-0.2	-0.6	-0.5	-1.0	0.5	-1.8	-1.4	-1.0	-0.3
Average weekly red wine intake	0.3	0.4	1.8	0.1	0.4	0.7	0.7	0.6	0.2	1.3	1.2	0.4	0.3	0.7
Average weekly champagne plus white wine intake	0.3	0.4	1.4	-0.3	-0.8	0.6	0.5	0.1	0.2	-0.2	1.2	0.8	1.1	0.5
Hearing aid user	0.3	0.3	1.2	1.1	0.8	0.3	0.2	0.3	1.0	0.3	-0.8	-0.2	-0.1	-0.1
Medication: Atorvastatin	0.3	0.4	1.3	-1.2	-0.5	0.9	0.7	1.0	0.6	-0.3	-0.2	0.4	0.0	0.7
Myopia	0.3	0.4	2.2	-0.3	-0.2	-0.7	-0.7	-0.8	-0.4	-1.5	0.1	-0.4	-0.4	-0.9
Supplements: Calcium	0.3	0.4	1.6	-1.3	-1.1	-0.0	0.5	0.5	0.4	-0.2	-0.5	0.3	0.1	0.6
Basal cell carcinoma (self-reported)	0.3	0.3	1.6	1.0	1.2	0.1	0.5	0.0	-0.6	-0.4	-0.5	-0.1	-0.3	0.5
Heart attack/myocardial infarction (self-reported)	0.3	0.3	1.0	0.6	0.8	0.0	-0.0	0.0	-0.2	-0.6	-1.0	-0.9	-0.9	-0.1
Leg fat mass (left)	0.3	1.0	4.8	2.2	1.2	-0.7	-0.3	-0.4	-0.7	-1.6	0.5	-0.8	-1.0	-0.2
Alzheimer’s Disease (in father)	0.2	0.3	1.3	0.5	0.5	-0.2	-0.4	-0.2	-0.4	-0.8	-1.1	-0.4	-0.2	-0.3
Age at First Birth	0.2	0.3	0.8	-0.1	0.6	0.5	-0.5	-0.2	0.9	0.0	0.7	0.2	-0.7	-0.6
Blood Eosinophil Count	0.2	1.5	8.0	0.4	-0.9	-1.6	-1.4	-1.0	-1.1	-2.8	-0.5	-0.7	-0.7	-1.2
Blood Red Count	0.2	2.2	4.3	-0.2	1.2	2.0	2.1	1.8	1.7	1.1	0.9	1.6	1.9	1.8
Heel T-Score	0.2	1.3	8.2	-1.4	-2.9	-0.8	-0.2	-0.8	-0.5	1.0	1.4	-0.7	-0.6	0.1
Lung FEV1/FVC ratio	0.2	1.0	5.5	-1.4	-2.3	-0.7	-0.3	-0.8	-0.3	0.3	0.8	-1.2	-1.3	-0.2
Sensitivity / hurt feelings	0.2	0.3	1.5	-0.7	-0.1	0.6	-0.0	0.4	0.3	-1.2	0.6	0.0	-0.9	-0.1
Pack years adult smoking proportion	0.2	0.2	0.7	0.5	0.2	0.0	0.4	0.7	0.7	-0.8	-0.6	-0.3	0.1	0.6
Serious illness, injury or assault to yourself	0.2	0.3	1.2	-0.3	-1.1	0.8	-0.1	0.5	0.2	-0.9	-0.3	0.1	-0.5	-0.2
High blood pressure	0.2	0.5	2.7	0.3	0.3	0.1	-0.4	-0.3	-0.8	0.9	-1.6	-1.0	-0.6	-0.1
Hayfever, allergic rhinitis or eczema	0.2	0.5	1.5	1.2	0.7	-0.9	0.1	-0.2	-0.5	1.2	-0.2	0.1	0.8	0.6
High blood pressure (mother)	0.2	0.3	1.3	-1.1	-0.7	1.1	0.4	0.3	0.4	-0.2	0.6	-0.1	-0.0	0.5
Hair/balding pattern: Pattern 2	0.2	0.2	1.2	-0.3	-0.2	-0.0	-0.5	-0.4	-0.7	-0.5	-1.1	-0.0	0.1	-0.4
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.5	3.7	1.9	-0.1	-0.9	-0.4	-0.4	-1.2	0.1	0.2	-0.2	0.2	0.0
Allergy	0.2	0.4	1.5	-0.9	-0.2	1.2	0.2	0.3	0.8	-0.4	0.6	-0.4	-1.1	-0.5
Illnesses of siblings	0.2	0.2	1.1	0.1	-0.1	-0.1	0.4	0.1	-0.1	-0.8	-0.0	0.7	1.1	0.6
Breastfed as a baby	0.2	0.2	0.6	-0.6	-0.1	0.3	0.5	0.7	0.8	0.3	-0.1	0.0	-0.3	0.6
Glaucoma (self-reported)	0.2	0.3	1.4	0.2	-0.5	0.1	-0.3	-0.4	-0.0	-0.4	-1.2	-0.9	-0.3	-0.3
Gout (self-reported)	0.2	0.2	1.3	0.2	0.3	-1.0	-0.2	-0.5	-0.0	-1.1	0.1	-0.1	0.2	-0.1
Exposure to tobacco smoke outside home	0.2	0.3	1.4	0.7	-0.4	0.4	0.3	0.5	-0.4	1.2	0.2	0.3	0.3	0.4
Number of full brothers	0.2	0.3	1.2	1.1	0.7	-0.3	-0.2	-0.3	0.1	0.2	0.5	-0.5	-1.0	-0.5
Angina (self-reported)	0.2	0.2	1.2	0.6	0.4	-0.0	-0.1	-0.3	-0.1	-1.1	-1.0	-0.2	-0.1	-0.3
Leg fat mass (right)	0.2	0.9	5.5	2.3	1.3	-0.5	-0.1	-0.3	-0.6	-1.2	0.4	-0.8	-1.1	-0.1
Pulse rate, automated reading	0.2	0.8	2.2	-0.5	0.5	1.5	0.9	0.8	1.4	-1.1	-0.2	1.0	0.8	0.4
Leg pain on walking	0.2	0.2	0.8	0.6	0.6	0.7	0.0	0.0	-0.1	-0.3	-0.9	-0.8	-0.4	-0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.2	0.2	1.0	0.3	1.0	0.4	0.5	0.0	0.3	-0.5	0.0	-0.0	0.7	0.7
Illnesses of siblings: Diabetes	0.2	0.3	1.4	0.5	1.2	-0.2	-0.5	-0.5	-0.3	-0.3	0.9	0.3	0.3	-0.2
Eye problems/disorders: Cataract	0.2	0.2	1.0	-1.0	-0.6	0.6	0.4	0.5	0.1	-0.0	-0.0	0.4	0.4	0.5
Arm fat mass (left)	0.2	1.0	6.6	2.6	1.7	-0.1	0.5	0.6	-0.0	-0.6	0.8	-0.2	-0.6	0.5
Illnesses of father: High blood pressure	0.2	0.3	1.2	-0.0	0.2	0.2	-0.8	-0.1	-0.2	-1.1	-0.6	-0.1	-0.6	-0.9
Vascular/heart problems diagnosed by doctor	0.2	0.5	3.0	-0.5	-0.6	-0.2	0.5	0.3	0.7	0.2	1.7	1.0	0.8	0.2
Pain experienced in last month	0.2	0.3	0.9	-0.7	-0.4	-0.6	-0.2	-0.1	0.2	0.9	1.0	0.1	-0.2	-0.5
Pack years of smoking	0.2	0.3	1.1	0.7	0.6	0.2	0.5	0.8	1.1	-0.6	-0.2	0.0	0.3	0.6
Intelligence (Savage-Jansen 2018)	0.1	0.2	0.7	-0.5	-0.6	-0.2	-0.7	-0.4	-0.4	-0.9	-0.3	0.1	0.1	-0.6
Blood Platelet Count	0.1	1.1	9.9	-1.2	0.1	-0.8	-0.5	-0.9	0.1	-0.3	3.1	0.5	-0.2	-0.2
Systolic Blood Pressure	0.1	0.7	1.8	-0.5	-0.9	1.3	1.2	0.6	0.5	0.3	0.6	0.9	1.2	1.3
Hair Pigment	0.1	1.7	5.4	-1.9	-2.3	-0.7	-1.0	-1.4	-1.5	0.8	-0.9	-1.2	-1.2	-0.9
Tanning	0.1	0.8	2.0	-1.4	-1.1	0.9	0.9	0.6	1.0	1.4	0.5	0.6	0.6	0.8
Angina	0.1	0.2	1.3	0.2	0.0	0.0	-0.0	-0.2	0.0	-1.1	-0.8	-0.2	-0.2	-0.2
Pain all over the body in last month	0.1	0.2	0.5	-0.7	-0.7	0.3	-0.1	0.0	-0.4	-0.2	-0.6	-0.2	0.5	0.1
Fluid intelligence score	0.1	0.3	1.5	-1.2	-0.7	0.3	-0.5	0.1	0.5	-0.2	-0.1	0.7	0.5	-0.5
Arm fat percentage (right)	0.1	0.5	1.8	1.3	0.8	-0.2	-0.1	0.0	-0.1	-1.3	0.6	-0.7	-1.1	-0.2
Asthma	0.1	0.3	1.0	0.2	-0.5	-0.1	-0.2	0.3	-0.1	-0.6	-0.8	1.0	1.0	0.1
Medication: Amlodipine	0.1	0.2	0.5	-0.6	0.3	0.1	0.4	0.3	0.4	0.1	-0.1	0.4	0.7	0.6
High blood pressure (siblings)	0.1	0.2	1.7	-0.1	-0.2	0.4	-0.1	0.2	0.3	1.3	0.2	-0.4	-0.6	-0.1
Body fat percentage	0.1	0.5	2.0	1.4	0.7	0.5	0.5	0.5	0.3	-1.2	0.8	0.1	-0.2	0.4
Seen a psychiatrist for nerves, anxiety, tension or depression	0.1	0.2	0.7	0.3	0.3	0.1	0.6	0.1	-0.9	0.3	-0.6	-0.1	0.5	0.5
Qualifications: College or University degree	0.1	0.4	3.0	1.7	0.5	-0.8	0.1	-0.3	0.1	0.2	0.1	-0.1	0.4	0.0
Medication: Allopurinol	0.1	0.1	0.3	0.1	-0.0	-0.5	-0.3	-0.1	-0.0	-0.3	-0.4	-0.4	-0.1	-0.2
Knee pain experienced in last month	0.1	0.2	0.4	0.5	0.1	0.6	0.3	0.4	0.4	-0.6	0.7	0.3	-0.4	0.3
Arm fat percentage (left)	0.1	0.5	1.8	1.3	0.4	-0.3	-0.2	-0.0	-0.1	-1.1	0.5	-0.7	-1.1	-0.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.1	0.1	0.9	-0.1	1.0	-0.1	-0.2	-0.1	0.0	0.5	-0.3	0.2	-0.2	-0.2
Asthma (self-reported)	0.1	0.3	0.8	0.1	-0.5	-0.3	-0.3	0.1	-0.4	-0.4	-0.9	0.8	0.9	-0.0
Diastolic blood pressure, automated reading	0.1	0.3	1.5	0.1	1.2	0.7	0.3	0.1	0.2	0.0	1.1	0.4	-0.2	0.3

Hub : Genes

PRDX3

Models

Trait associations