[Hub]/) : Traits : Leg fat-free mass (right) : ← →

chr10:123,438,113-124,889,817

Best TWAS P=4.38e-14 · Best GWAS P=2.16e-11 conditioned to 0.286

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous PLEKHA1 0.14 0.06 lasso 2 0.03 2.4e-03 6.5 -6.7 3.0e-11 0.76 0.02 0.97 FALSE
2 GTEx Muscle Skeletal PLEKHA1 0.10 0.04 lasso 3 0.04 8.2e-05 -6.6 -5.9 3.1e-09 0.86 0.02 0.97 FALSE
3 GTEx Nerve Tibial PLEKHA1 0.22 0.23 enet 17 0.19 1.1e-13 6.5 -6.1 1.2e-09 0.64 0.02 0.98 FALSE
4 GTEx Skin Sun Exposed Lower leg PLEKHA1 0.16 0.02 lasso 5 0.01 4.0e-02 -6.4 -6.7 2.8e-11 0.81 0.03 0.94 FALSE
5 METSIM Adipose PLEKHA1 0.05 0.03 lasso 4 0.04 3.6e-07 6.5 -7.5 4.4e-14 0.80 0.02 0.98 TRUE
6 ROSMAP Brain Pre-frontal Cortex PLEKHA1 0.06 0.05 lasso 4 0.05 1.3e-06 -6.6 -6.6 3.9e-11 0.99 0.01 0.99 FALSE
7 The Cancer Genome Atlas Brain Lower Grade Glioma PLEKHA1 0.04 0.05 lasso 2 0.04 4.3e-05 6.5 -6.5 7.2e-11 0.77 0.02 0.98 FALSE
8 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma PLEKHA1 0.08 0.06 blup 103 0.02 4.0e-02 6.5 -5.8 7.7e-09 0.83 0.02 0.84 FALSE
9 The Cancer Genome Atlas Prostate Adenocarcinoma ARMS2 0.06 0.04 blup 71 0.05 4.9e-06 -6.6 -5.5 3.8e-08 0.81 0.01 0.99 FALSE
10 The Cancer Genome Atlas Thyroid Carcinoma PLEKHA1 0.08 0.10 lasso 1 0.09 3.5e-09 6.5 -6.5 7.4e-11 0.77 0.02 0.98 FALSE