[Hub]/) : Traits : Leg fat-free mass (right) : ← →

chr11:71,619,100-73,149,098

Best TWAS P=1.84e-10 · Best GWAS P=6.45e-11 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Esophagus Mucosa ARAP1 0.27 0.25 lasso 5 0.26 2.6e-17 5.5 5.3 8.7e-08 0.54 0.31 0.69 FALSE
2 GTEx Esophagus Mucosa ARAP1-AS2 0.12 0.08 lasso 6 0.08 3.1e-06 5.5 5.3 1.1e-07 0.53 0.21 0.61 FALSE
3 GTEx Esophagus Mucosa ARAP1-AS1 0.15 0.12 enet 7 0.13 4.1e-09 5.5 5.2 2.3e-07 0.53 0.37 0.63 FALSE
4 GTEx Pituitary PDE2A 0.25 0.19 lasso 5 0.17 4.1e-05 6.1 6.1 1.1e-09 0.94 0.00 0.96 FALSE
5 GTEx Pituitary RP11-169D4.2 0.19 0.20 lasso 2 0.16 7.3e-05 6.1 6.4 1.8e-10 0.98 0.00 0.97 TRUE
6 GTEx Skin Not Sun Exposed Suprapubic ARAP1 0.24 0.20 lasso 4 0.16 3.6e-09 5.5 5.4 6.1e-08 0.55 0.32 0.68 FALSE
7 GTEx Skin Not Sun Exposed Suprapubic ARAP1-AS2 0.20 0.08 lasso 5 0.05 1.5e-03 4.0 5.4 6.6e-08 0.58 0.18 0.72 FALSE
8 GTEx Skin Not Sun Exposed Suprapubic ARAP1-AS1 0.14 0.13 lasso 4 0.07 9.1e-05 5.5 5.6 2.3e-08 0.59 0.25 0.73 FALSE
9 GTEx Skin Sun Exposed Lower leg ARAP1 0.21 0.13 lasso 7 0.13 1.2e-10 5.5 5.2 2.5e-07 0.52 0.33 0.67 FALSE
10 The Cancer Genome Atlas Breast Invasive Carcinoma PDE2A 0.02 0.02 lasso 2 0.02 2.0e-04 6.1 -6.1 1.0e-09 -0.94 0.02 0.92 FALSE