[Hub]/) : Traits : Leg fat-free mass (right) :

chr1:25,752,617-27,293,356

Best TWAS P=1.15e-10 · Best GWAS P=2.7e-10 conditioned to 0.111

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Esophagus Mucosa PDIK1L 0.10 0.09 lasso 6 0.09 8.8e-07 6.1 -5.9 4.3e-09 -0.95 0.02 0.98 FALSE
2 GTEx Thyroid CNKSR1 0.10 0.04 lasso 7 0.03 2.1e-03 5.1 -5.4 7.1e-08 -0.73 0.11 0.87 FALSE
3 GTEx Whole Blood CEP85 0.07 0.01 enet 17 0.02 1.3e-02 -2.8 -5.2 2.2e-07 -0.29 0.16 0.41 FALSE
4 The Cancer Genome Atlas Bladder Urothelial Carcinoma TRIM63 0.03 0.02 blup 33 0.02 4.6e-03 6.2 6.0 2.4e-09 0.91 0.01 0.89 FALSE
5 The Cancer Genome Atlas Breast Invasive Carcinoma TRIM63 0.15 0.16 lasso 2 0.16 2.3e-32 6.2 6.3 3.9e-10 0.97 0.00 1.00 FALSE
6 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma TRIM63 0.14 0.15 lasso 1 0.14 2.2e-07 6.2 6.2 5.5e-10 0.95 0.00 1.00 FALSE
7 The Cancer Genome Atlas Colon Adenocarcinoma TRIM63 0.08 0.10 lasso 4 0.10 3.7e-06 6.0 5.8 8.5e-09 0.95 0.01 0.99 FALSE
8 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma GRRP1 0.11 0.02 blup 52 0.03 8.8e-05 -3.0 5.2 2.1e-07 0.47 0.02 0.27 FALSE
9 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma PDIK1L 0.02 0.02 blup 37 0.02 2.8e-03 6.1 -6.1 9.5e-10 -0.93 0.01 0.83 FALSE
10 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma TRIM63 0.11 0.11 enet 4 0.12 9.0e-14 6.0 5.4 8.1e-08 0.95 0.01 0.99 FALSE
11 The Cancer Genome Atlas Brain Lower Grade Glioma PDIK1L 0.03 0.01 blup 37 0.02 2.6e-03 5.1 -6.5 1.2e-10 -0.85 0.01 0.55 TRUE
12 The Cancer Genome Atlas Brain Lower Grade Glioma TRIM63 0.29 0.33 enet 20 0.33 2.5e-38 6.0 6.4 1.5e-10 0.92 0.01 0.99 FALSE
13 The Cancer Genome Atlas Lung Adenocarcinoma TRIM63 0.14 0.20 enet 7 0.21 9.4e-24 6.0 5.7 1.5e-08 0.95 0.01 0.99 FALSE
14 The Cancer Genome Atlas Lung Squamous Cell Carcinoma TRIM63 0.16 0.11 lasso 1 0.10 2.0e-11 6.0 6.0 1.5e-09 0.96 0.01 0.99 FALSE
15 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma TRIM63 0.14 0.18 lasso 7 0.15 3.0e-10 6.0 5.8 6.1e-09 0.95 0.01 0.99 FALSE
16 The Cancer Genome Atlas Rectum Adenocarcinoma TRIM63 0.28 0.22 lasso 3 0.20 1.7e-05 4.1 5.1 3.1e-07 0.72 0.02 0.90 FALSE
17 The Cancer Genome Atlas Thyroid Carcinoma TRIM63 0.18 0.26 enet 7 0.26 3.0e-25 6.0 6.0 2.3e-09 0.94 0.01 0.99 FALSE
18 The Cancer Genome Atlas Uterine Corpus Endometrial Carcinoma TRIM63 0.19 0.07 blup 33 0.14 1.3e-04 6.0 5.5 3.9e-08 0.88 0.01 0.99 FALSE