[Hub]/) : Traits : Leg fat-free mass (right) : ← →

chr1:25,752,617-27,293,356

Best TWAS P=1.15e-10 · Best GWAS P=2.7e-10 conditioned to 0.111

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
11	The Cancer Genome Atlas	Brain Lower Grade Glioma	PDIK1L	0.03	0.01	blup	37	0.02	2.6e-03	5.1	-6.5	1.2e-10	-0.85	0.01	0.55	TRUE
12	The Cancer Genome Atlas	Brain Lower Grade Glioma	TRIM63	0.29	0.33	enet	20	0.33	2.5e-38	6.0	6.4	1.5e-10	0.92	0.01	0.99	FALSE
5	The Cancer Genome Atlas	Breast Invasive Carcinoma	TRIM63	0.15	0.16	lasso	2	0.16	2.3e-32	6.2	6.3	3.9e-10	0.97	0.00	1.00	FALSE
6	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	TRIM63	0.14	0.15	lasso	1	0.14	2.2e-07	6.2	6.2	5.5e-10	0.95	0.00	1.00	FALSE
9	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	PDIK1L	0.02	0.02	blup	37	0.02	2.8e-03	6.1	-6.1	9.5e-10	-0.93	0.01	0.83	FALSE
14	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	TRIM63	0.16	0.11	lasso	1	0.10	2.0e-11	6.0	6.0	1.5e-09	0.96	0.01	0.99	FALSE
17	The Cancer Genome Atlas	Thyroid Carcinoma	TRIM63	0.18	0.26	enet	7	0.26	3.0e-25	6.0	6.0	2.3e-09	0.94	0.01	0.99	FALSE
4	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	TRIM63	0.03	0.02	blup	33	0.02	4.6e-03	6.2	6.0	2.4e-09	0.91	0.01	0.89	FALSE
1	GTEx	Esophagus Mucosa	PDIK1L	0.10	0.09	lasso	6	0.09	8.8e-07	6.1	-5.9	4.3e-09	-0.95	0.02	0.98	FALSE
15	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	TRIM63	0.14	0.18	lasso	7	0.15	3.0e-10	6.0	5.8	6.1e-09	0.95	0.01	0.99	FALSE
7	The Cancer Genome Atlas	Colon Adenocarcinoma	TRIM63	0.08	0.10	lasso	4	0.10	3.7e-06	6.0	5.8	8.5e-09	0.95	0.01	0.99	FALSE
13	The Cancer Genome Atlas	Lung Adenocarcinoma	TRIM63	0.14	0.20	enet	7	0.21	9.4e-24	6.0	5.7	1.5e-08	0.95	0.01	0.99	FALSE
18	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	TRIM63	0.19	0.07	blup	33	0.14	1.3e-04	6.0	5.5	3.9e-08	0.88	0.01	0.99	FALSE
2	GTEx	Thyroid	CNKSR1	0.10	0.04	lasso	7	0.03	2.1e-03	5.1	-5.4	7.1e-08	-0.73	0.11	0.87	FALSE
10	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	TRIM63	0.11	0.11	enet	4	0.12	9.0e-14	6.0	5.4	8.1e-08	0.95	0.01	0.99	FALSE
8	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	GRRP1	0.11	0.02	blup	52	0.03	8.8e-05	-3.0	5.2	2.1e-07	0.47	0.02	0.27	FALSE
3	GTEx	Whole Blood	CEP85	0.07	0.01	enet	17	0.02	1.3e-02	-2.8	-5.2	2.2e-07	-0.29	0.16	0.41	FALSE
16	The Cancer Genome Atlas	Rectum Adenocarcinoma	TRIM63	0.28	0.22	lasso	3	0.20	1.7e-05	4.1	5.1	3.1e-07	0.72	0.02	0.90	FALSE