Best TWAS P=1.34e-13 · Best GWAS P=5.91e-17 conditioned to 4.68e-11
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | FNDC3B | 0.07 | 0.06 | enet | 8 | 0.05 | 3.2e-07 | -7.7 | 7.4 | 1.3e-13 | 0.06 | 0.33 | 0.66 | TRUE |
| 2 | YFS | Blood | TNFSF10 | 0.09 | 0.04 | bslmm | 462 | 0.08 | 1.6e-24 | 5.6 | 6.3 | 2.6e-10 | 0.25 | 1.00 | 0.00 | TRUE |
| 3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | FNDC3B | 0.07 | 0.02 | enet | 6 | 0.02 | 3.9e-03 | 5.4 | -5.9 | 4.2e-09 | -0.71 | 0.01 | 0.96 | FALSE |