[Hub]/) : Traits : Leg fat-free mass (right) : ← →

chr3:182,655,858-186,072,370

Best TWAS P=4.75e-23 · Best GWAS P=3.01e-22 conditioned to 0.128

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	ECE2	0.24	0.20	bslmm	542	0.19	1.6e-22	9.0	8.8	1.1e-18	-0.37	0.36	0.64	FALSE
2	CommonMind	Brain Pre-frontal Cortex	SENP2	0.21	0.18	enet	33	0.19	4.2e-22	-5.4	5.5	3.5e-08	0.02	1.00	0.00	TRUE
3	GTEx	Adipose Subcutaneous	KLHL24	0.15	0.10	lasso	6	0.10	1.4e-08	-5.1	5.1	2.9e-07	-0.04	0.04	0.96	FALSE
4	GTEx	Artery Tibial	PSMD2	0.13	0.09	lasso	5	0.08	1.3e-06	-5.8	6.1	1.2e-09	-0.42	0.88	0.02	FALSE
5	GTEx	Brain Cerebellum	KLHL24	0.52	0.14	enet	26	0.16	1.9e-05	-5.1	5.5	3.3e-08	-0.04	0.04	0.95	TRUE
6	GTEx	Brain Putamen basal ganglia	ECE2	0.38	0.03	enet	22	0.11	1.4e-03	9.0	6.4	1.3e-10	-0.28	0.08	0.18	FALSE
7	GTEx	Breast Mammary Tissue	KLHL24	0.25	0.13	lasso	5	0.11	3.4e-06	-5.1	5.2	2.0e-07	-0.05	0.04	0.96	FALSE
8	GTEx	Esophagus Mucosa	ABCF3	0.11	0.10	lasso	3	0.08	3.6e-06	-5.7	5.8	5.3e-09	-0.31	0.37	0.54	TRUE
9	GTEx	Pancreas	ECE2	0.26	0.04	enet	24	0.09	1.2e-04	9.0	6.2	5.6e-10	-0.24	0.14	0.22	FALSE
10	GTEx	Pituitary	ECE2	0.52	0.30	lasso	7	0.23	1.5e-06	9.0	7.9	3.4e-15	-0.31	0.23	0.54	TRUE
11	GTEx	Skin Sun Exposed Lower leg	KLHL24	0.09	0.06	lasso	10	0.05	9.5e-05	-5.1	5.1	3.0e-07	-0.04	0.04	0.95	FALSE
12	GTEx	Skin Sun Exposed Lower leg	ABCF3	0.13	0.08	lasso	4	0.11	1.6e-09	5.4	7.2	5.2e-13	-0.36	0.98	0.01	FALSE
13	GTEx	Skin Sun Exposed Lower leg	PSMD2	0.13	0.14	lasso	4	0.15	1.4e-12	-5.8	5.8	6.6e-09	-0.39	1.00	0.00	FALSE
14	YFS	Blood	PSMD2	0.26	0.22	lasso	5	0.24	2.4e-77	-5.8	5.6	2.0e-08	-0.39	1.00	0.00	FALSE
15	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	ETV5	0.03	0.01	blup	55	0.02	1.3e-03	-8.4	-8.2	2.2e-16	-0.04	0.01	0.86	TRUE
16	The Cancer Genome Atlas	Brain Lower Grade Glioma	ECE2	0.04	0.02	blup	61	0.03	3.5e-04	9.0	8.2	1.6e-16	-0.24	0.31	0.44	FALSE
17	The Cancer Genome Atlas	Brain Lower Grade Glioma	KLHL24	0.05	0.05	blup	53	0.05	1.1e-06	-5.1	5.1	2.9e-07	-0.05	0.02	0.98	FALSE
18	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	ABCF3	0.08	0.03	blup	51	0.06	6.1e-04	2.4	5.3	1.1e-07	-0.25	0.01	0.81	FALSE
19	The Cancer Genome Atlas	Lung Adenocarcinoma	PSMD2	0.09	0.02	blup	50	0.05	1.2e-06	-9.3	9.9	4.8e-23	-0.73	0.03	0.86	TRUE
20	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	CAMK2N2	0.04	0.01	enet	8	0.03	3.9e-04	3.4	6.0	1.8e-09	-0.32	0.14	0.08	FALSE
21	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	PSMD2	0.05	0.00	enet	10	0.01	3.6e-02	9.0	7.0	2.4e-12	-0.49	0.01	0.11	FALSE
22	The Cancer Genome Atlas	Testicular Germ Cell Tumors	VWA5B2	0.10	0.04	blup	51	0.04	1.8e-02	5.4	-8.8	1.6e-18	0.43	0.03	0.33	FALSE