Best TWAS P=7.76e-33 · Best GWAS P=4.64e-39 conditioned to 0.782
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | OTUD4 | 0.06 | 0.04 | bslmm | 272 | 0.04 | 2.6e-05 | -10.0 | -7.7 | 1.8e-14 | -0.39 | 0.83 | 0.05 | FALSE |
| 2 | GTEx | Brain Hypothalamus | HHIP-AS1 | 0.12 | 0.02 | enet | 16 | 0.04 | 4.6e-02 | 8.6 | 8.3 | 1.4e-16 | 0.21 | 0.07 | 0.08 | TRUE |
| 3 | GTEx | Pancreas | ANAPC10 | 0.14 | 0.10 | lasso | 3 | 0.10 | 4.3e-05 | -11.4 | 11.1 | 1.8e-28 | 0.60 | 0.32 | 0.11 | TRUE |
| 4 | ROSMAP | Brain Pre-frontal Cortex | OTUD4 | 0.04 | 0.03 | lasso | 2 | 0.03 | 1.4e-04 | 11.8 | -11.9 | 7.8e-33 | -0.85 | 0.12 | 0.82 | TRUE |