Best TWAS P=8.72e-28 · Best GWAS P=1.65e-38 conditioned to 1.87e-12
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | CEP120 | 0.12 | 0.08 | lasso | 3 | 0.05 | 5.5e-05 | 4.8 | 5.3 | 1.1e-07 | -0.29 | 0.87 | 0.01 | FALSE |
| 2 | GTEx | Artery Aorta | CSNK1G3 | 0.11 | 0.07 | lasso | 2 | 0.01 | 6.5e-02 | -6.4 | -6.6 | 3.6e-11 | 0.52 | 0.15 | 0.09 | FALSE |
| 3 | GTEx | Artery Aorta | KRT8P33 | 0.10 | 0.04 | lasso | 6 | 0.05 | 9.1e-04 | -6.4 | 8.8 | 2.2e-18 | -0.62 | 0.03 | 0.87 | FALSE |
| 4 | GTEx | Esophagus Mucosa | CSNK1G3 | 0.14 | 0.05 | lasso | 3 | 0.07 | 2.0e-05 | 7.3 | 7.2 | 5.1e-13 | -0.44 | 0.78 | 0.11 | FALSE |
| 5 | The Cancer Genome Atlas | Breast Invasive Carcinoma | CSNK1G3 | 0.04 | 0.02 | enet | 8 | 0.02 | 1.2e-04 | 7.5 | 8.6 | 8.0e-18 | -0.56 | 0.00 | 0.92 | FALSE |
| 6 | The Cancer Genome Atlas | Colon Adenocarcinoma | CEP120 | 0.06 | 0.02 | blup | 70 | 0.04 | 3.6e-03 | 5.4 | 8.3 | 1.1e-16 | -0.64 | 0.13 | 0.15 | FALSE |
| 7 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | CEP120 | 0.03 | 0.02 | enet | 5 | 0.04 | 7.3e-05 | -6.4 | 8.4 | 5.2e-17 | -0.66 | 0.03 | 0.83 | FALSE |
| 8 | The Cancer Genome Atlas | Lung Adenocarcinoma | CSNK1G3 | 0.06 | 0.05 | lasso | 2 | 0.04 | 2.0e-05 | 7.3 | 7.2 | 5.5e-13 | -0.44 | 0.00 | 1.00 | FALSE |
| 9 | The Cancer Genome Atlas | Prostate Adenocarcinoma | CEP120 | 0.10 | 0.14 | blup | 70 | 0.14 | 2.6e-14 | -11.9 | 10.9 | 8.7e-28 | -0.83 | 0.17 | 0.83 | TRUE |
| 10 | The Cancer Genome Atlas | Prostate Adenocarcinoma | CSNK1G3 | 0.06 | 0.04 | enet | 10 | 0.05 | 2.3e-06 | 7.0 | 8.4 | 4.4e-17 | -0.57 | 0.05 | 0.94 | FALSE |