[Hub]/) : Traits : Leg predicted mass (right) : ← →

chr8:37,329,315-38,932,193

Best TWAS P=3.71e-09 · Best GWAS P=8.66e-09 conditioned to 0.108

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	DDHD2	0.04	0.04	bslmm	286	0.04	2.0e-05	-5.2	-5.2	2.3e-07	0.93	0.03	0.97	FALSE
2	GTEx	Adrenal Gland	DDHD2	0.25	0.21	lasso	2	0.19	1.7e-07	-5.6	-5.5	3.4e-08	0.98	0.03	0.97	FALSE
3	GTEx	Artery Tibial	DDHD2	0.07	0.07	lasso	2	0.05	7.3e-05	-5.6	-5.6	2.6e-08	0.99	0.03	0.97	FALSE
4	GTEx	Breast Mammary Tissue (Female)	RP11-350N15.5	0.12	0.10	lasso	2	0.07	3.9e-03	-5.8	5.7	1.1e-08	-0.99	0.02	0.88	FALSE
5	GTEx	Colon Sigmoid	DDHD2	0.15	0.15	lasso	3	0.12	7.5e-05	-5.2	-5.2	1.6e-07	0.95	0.05	0.90	FALSE
6	GTEx	Liver	DDHD2	0.29	0.01	lasso	5	-0.01	5.4e-01	-5.4	-5.3	1.1e-07	0.89	0.03	0.67	FALSE
7	GTEx	Pituitary	DDHD2	0.25	0.22	lasso	3	0.17	3.9e-05	-5.4	-5.1	3.0e-07	0.92	0.03	0.91	FALSE
8	GTEx	Spleen	DDHD2	0.17	0.17	lasso	2	0.11	7.8e-04	-5.6	-5.6	1.9e-08	0.98	0.03	0.90	FALSE
9	GTEx	Stomach	DDHD2	0.13	0.06	lasso	2	0.06	1.1e-03	-5.4	-5.4	5.3e-08	0.96	0.04	0.88	FALSE
10	GTEx	Thyroid	DDHD2	0.11	0.10	lasso	4	0.09	3.8e-07	-5.1	-5.2	2.5e-07	0.94	0.05	0.95	FALSE
11	NTR	Blood	BAG4	0.01	0.01	blup	253	0.01	3.9e-03	-5.1	5.8	7.1e-09	-0.94	0.05	0.92	FALSE
12	ROSMAP	Brain Pre-frontal Cortex	PPAPDC1B	0.06	0.08	enet	14	0.09	4.0e-11	-5.7	-5.5	3.0e-08	0.99	0.03	0.97	FALSE
13	ROSMAP	Brain Pre-frontal Cortex	LSM1	0.09	0.16	lasso	6	0.16	7.3e-20	-5.1	5.2	1.8e-07	-0.95	0.23	0.77	FALSE
14	YFS	Blood	BAG4	0.01	0.01	bslmm	234	0.00	2.6e-02	-4.7	-5.9	3.7e-09	0.82	0.06	0.71	TRUE
15	YFS	Blood	LSM1	0.02	0.00	bslmm	218	0.01	4.1e-04	-3.1	5.9	4.7e-09	-0.83	0.04	0.94	FALSE
16	The Cancer Genome Atlas	Breast Invasive Carcinoma	DDHD2	0.01	0.01	blup	21	0.01	2.3e-03	-5.6	-5.6	2.3e-08	0.96	0.02	0.74	FALSE
17	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	DDHD2	0.03	0.03	blup	21	0.03	3.5e-04	-5.3	-5.6	2.1e-08	0.98	0.02	0.98	FALSE
18	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	PPAPDC1B	0.02	0.00	blup	18	0.01	4.2e-02	-5.4	-5.7	1.3e-08	0.96	0.01	0.54	FALSE
19	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	DDHD2	0.07	0.05	blup	21	0.05	2.7e-03	-5.2	-5.4	6.1e-08	0.96	0.02	0.66	FALSE
20	The Cancer Genome Atlas	Prostate Adenocarcinoma	DDHD2	0.11	0.08	lasso	3	0.08	1.9e-08	-5.2	-5.2	1.7e-07	0.95	0.04	0.96	FALSE
21	The Cancer Genome Atlas	Thyroid Carcinoma	DDHD2	0.02	0.01	blup	21	0.01	2.4e-02	-5.7	-5.5	4.2e-08	0.98	0.01	0.79	FALSE