[Hub]/) : Traits : Leg predicted mass (right) :

chr8:37,329,315-38,932,193

Best TWAS P=3.71e-09 · Best GWAS P=8.66e-09 conditioned to 0.108

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex DDHD2 0.04 0.04 bslmm 286 0.04 2.0e-05 -5.2 -5.2 2.3e-07 0.93 0.03 0.97 FALSE
2 GTEx Adrenal Gland DDHD2 0.25 0.21 lasso 2 0.19 1.7e-07 -5.6 -5.5 3.4e-08 0.98 0.03 0.97 FALSE
3 GTEx Artery Tibial DDHD2 0.07 0.07 lasso 2 0.05 7.3e-05 -5.6 -5.6 2.6e-08 0.99 0.03 0.97 FALSE
4 GTEx Breast Mammary Tissue (Female) RP11-350N15.5 0.12 0.10 lasso 2 0.07 3.9e-03 -5.8 5.7 1.1e-08 -0.99 0.02 0.88 FALSE
5 GTEx Colon Sigmoid DDHD2 0.15 0.15 lasso 3 0.12 7.5e-05 -5.2 -5.2 1.6e-07 0.95 0.05 0.90 FALSE
6 GTEx Liver DDHD2 0.29 0.01 lasso 5 -0.01 5.4e-01 -5.4 -5.3 1.1e-07 0.89 0.03 0.67 FALSE
7 GTEx Pituitary DDHD2 0.25 0.22 lasso 3 0.17 3.9e-05 -5.4 -5.1 3.0e-07 0.92 0.03 0.91 FALSE
8 GTEx Spleen DDHD2 0.17 0.17 lasso 2 0.11 7.8e-04 -5.6 -5.6 1.9e-08 0.98 0.03 0.90 FALSE
9 GTEx Stomach DDHD2 0.13 0.06 lasso 2 0.06 1.1e-03 -5.4 -5.4 5.3e-08 0.96 0.04 0.88 FALSE
10 GTEx Thyroid DDHD2 0.11 0.10 lasso 4 0.09 3.8e-07 -5.1 -5.2 2.5e-07 0.94 0.05 0.95 FALSE
11 NTR Blood BAG4 0.01 0.01 blup 253 0.01 3.9e-03 -5.1 5.8 7.1e-09 -0.94 0.05 0.92 FALSE
12 ROSMAP Brain Pre-frontal Cortex PPAPDC1B 0.06 0.08 enet 14 0.09 4.0e-11 -5.7 -5.5 3.0e-08 0.99 0.03 0.97 FALSE
13 ROSMAP Brain Pre-frontal Cortex LSM1 0.09 0.16 lasso 6 0.16 7.3e-20 -5.1 5.2 1.8e-07 -0.95 0.23 0.77 FALSE
14 YFS Blood BAG4 0.01 0.01 bslmm 234 0.00 2.6e-02 -4.7 -5.9 3.7e-09 0.82 0.06 0.71 TRUE
15 YFS Blood LSM1 0.02 0.00 bslmm 218 0.01 4.1e-04 -3.1 5.9 4.7e-09 -0.83 0.04 0.94 FALSE
16 The Cancer Genome Atlas Breast Invasive Carcinoma DDHD2 0.01 0.01 blup 21 0.01 2.3e-03 -5.6 -5.6 2.3e-08 0.96 0.02 0.74 FALSE
17 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma DDHD2 0.03 0.03 blup 21 0.03 3.5e-04 -5.3 -5.6 2.1e-08 0.98 0.02 0.98 FALSE
18 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma PPAPDC1B 0.02 0.00 blup 18 0.01 4.2e-02 -5.4 -5.7 1.3e-08 0.96 0.01 0.54 FALSE
19 The Cancer Genome Atlas Pancreatic Adenocarcinoma DDHD2 0.07 0.05 blup 21 0.05 2.7e-03 -5.2 -5.4 6.1e-08 0.96 0.02 0.66 FALSE
20 The Cancer Genome Atlas Prostate Adenocarcinoma DDHD2 0.11 0.08 lasso 3 0.08 1.9e-08 -5.2 -5.2 1.7e-07 0.95 0.04 0.96 FALSE
21 The Cancer Genome Atlas Thyroid Carcinoma DDHD2 0.02 0.01 blup 21 0.01 2.4e-02 -5.7 -5.5 4.2e-08 0.98 0.01 0.79 FALSE