[Hub]/) : Traits : Leg predicted mass (right) : ← →

chr11:64,407,419-66,333,072

Best TWAS P=4.46e-09 · Best GWAS P=4.49e-10 conditioned to 0.00127

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	FIBP	0.08	0.11	enet	20	0.12	8.1e-14	3.5	5.2	1.8e-07	-0.42	1.00	0.00	FALSE
2	GTEx	Brain Cerebellar Hemisphere	EFEMP2	0.35	0.15	enet	5	0.09	2.2e-03	5.5	5.8	7.3e-09	-0.49	0.09	0.74	FALSE
3	GTEx	Brain Cerebellum	EFEMP2	0.45	0.40	enet	8	0.39	1.6e-12	5.3	5.6	2.6e-08	-0.48	0.13	0.87	FALSE
4	GTEx	Cells Transformed fibroblasts	EFEMP2	0.06	0.06	lasso	3	0.07	7.8e-06	5.6	5.7	1.0e-08	-0.45	0.13	0.84	FALSE
5	GTEx	Colon Transverse	DPF2	0.19	0.01	lasso	4	0.05	1.6e-03	3.3	5.5	4.4e-08	-0.08	0.09	0.06	TRUE
6	METSIM	Adipose	EFEMP2	0.07	0.05	lasso	8	0.04	4.2e-06	4.8	5.2	2.2e-07	-0.48	0.50	0.50	FALSE
7	The Cancer Genome Atlas	Breast Invasive Carcinoma	EFEMP2	0.04	0.02	lasso	5	0.02	1.4e-05	5.7	5.6	2.2e-08	-0.48	0.08	0.91	FALSE
8	The Cancer Genome Atlas	Glioblastoma Multiforme	CTSW	0.16	0.18	enet	16	0.19	2.3e-06	5.1	-5.9	4.5e-09	0.52	0.17	0.64	TRUE
9	The Cancer Genome Atlas	Glioblastoma Multiforme	DKFZp761E198	0.14	0.00	blup	39	0.05	1.4e-02	-4.7	-5.2	2.1e-07	0.62	0.01	0.18	FALSE
10	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	DKFZp761E198	0.07	0.02	blup	39	0.03	5.9e-04	-4.8	-5.8	8.3e-09	0.73	0.02	0.63	FALSE
11	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	DPF2	0.07	0.04	blup	28	0.04	2.9e-05	-4.9	5.3	9.4e-08	-0.16	0.00	0.96	FALSE
12	The Cancer Genome Atlas	Brain Lower Grade Glioma	DPF2	0.03	0.02	blup	28	0.02	1.2e-03	-4.9	5.5	4.9e-08	-0.15	0.00	0.90	FALSE
13	The Cancer Genome Atlas	Brain Lower Grade Glioma	EFEMP2	0.01	0.00	blup	45	0.01	3.0e-02	2.6	5.2	2.5e-07	-0.45	0.04	0.16	FALSE
14	The Cancer Genome Atlas	Lung Adenocarcinoma	FIBP	0.02	0.01	blup	45	0.02	1.3e-03	3.7	5.3	1.3e-07	-0.48	0.08	0.35	FALSE
15	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	CAPN1	0.03	0.02	blup	39	0.02	2.1e-03	-4.9	-5.2	2.5e-07	0.18	0.00	0.93	FALSE
16	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	POLA2	0.12	0.03	enet	9	0.05	2.5e-04	-4.9	5.2	1.9e-07	-0.13	0.01	0.66	FALSE
17	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	CTSW	0.16	0.10	enet	24	0.15	1.9e-06	3.5	-5.2	2.5e-07	0.44	0.62	0.14	FALSE
18	The Cancer Genome Atlas	Soft Tissue Sarcoma	POLA2	0.09	0.06	blup	34	0.08	1.4e-05	-5.1	5.2	1.6e-07	-0.19	0.01	0.96	FALSE
19	The Cancer Genome Atlas	Soft Tissue Sarcoma	SNX32	0.08	0.08	lasso	2	0.10	1.5e-06	5.6	5.4	8.4e-08	-0.42	0.16	0.83	FALSE
20	The Cancer Genome Atlas	Thyroid Carcinoma	DPF2	0.05	0.02	blup	29	0.03	3.7e-04	-4.9	5.3	9.9e-08	-0.14	0.00	0.86	FALSE