Hub : Genes

ATXN7L2

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Artery Tibial	0.2261	0.0595	2.3e-05	0.031	NA	0.108	NA	0.096	1.6e-03	NA	9.1e-09	NA	5.8e-08
2	GTEx	Brain Cerebellar Hemisphere	0.2370	0.1010	9.8e-03	-0.011	NA	-0.007	NA	-0.008	9.1e-01	NA	5.3e-01	NA	5.9e-01
3	GTEx	Liver	0.3870	0.1170	1.3e-04	0.039	NA	0.190	NA	0.214	3.0e-02	NA	5.3e-06	NA	1.3e-06
4	GTEx	Ovary	0.1800	0.0650	9.4e-04	0.180	NA	0.126	NA	0.123	3.5e-05	NA	5.6e-04	NA	6.1e-04
5	GTEx	Testis	0.2840	0.0560	1.8e-12	0.339	NA	0.285	NA	0.327	1.0e-15	NA	4.2e-13	NA	3.7e-15
6	GTEx	Thyroid	0.1520	0.0430	3.0e-08	0.153	NA	0.128	NA	0.152	8.8e-12	NA	5.3e-10	NA	1.0e-11
7	ROSMAP	Brain Pre-frontal Cortex	0.0734	0.0228	5.1e-07	0.058	0.044	0.093	0.064	0.090	6.4e-08	2.4e-06	5.6e-12	1.1e-08	1.1e-11
8	TCGA	Thyroid Carcinoma	0.0650	0.0360	1.5e-05	0.057	0.050	0.045	NA	0.053	3.3e-06	1.1e-05	3.1e-05	NA	6.6e-06

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Bipolar Disorder (2018)	2.8	4.4	6.3	1.6	2.5	1.9	-2.5	-2.3	-2.2	-1.3	-2.3
Bipolar Disorder or Schizophrenia	0.7	1.7	3.2	0.9	0.7	1.8	-1.5	-1.5	-0.8	-1.4	-1.3
Depressed Affect (Nagel 2018)	0.5	1.1	3.8	0.8	1.8	0.5	0.3	0.3	0.4	1.9	0.3
Depression (Nagel 2018)	0.8	1.2	4.2	1.6	2.1	1.1	-0.7	-0.8	0.6	0.4	-0.5
Intelligence (Savage-Jansen 2018)	8.5	26.0	39.2	2.9	4.5	4.6	-6.3	-6.2	-5.1	-3.9	-6.2
Neuroticism (Nagel 2018)	1.2	2.7	6.0	1.0	2.4	1.4	-1.7	-1.7	-1.5	-0.8	-1.9
Schizophrenia (2018)	0.2	0.4	1.3	-0.2	-1.1	0.8	0.0	-0.1	0.8	-0.8	0.2
Schizophrenia vs Biploar Disorder	0.9	1.2	2.3	-0.7	-1.5	-0.5	1.5	1.1	1.3	0.3	1.2
Worry (Nagel 2018)	1.1	2.2	3.7	0.4	1.1	0.9	-1.7	-1.7	-1.8	-1.8	-1.9
Alzheimer’s Disease (in mother)	0.1	0.1	0.2	0.0	-0.1	-0.1	-0.4	-0.3	-0.4	-0.3	-0.4
Alzheimer’s Disease (in father)	0.9	1.0	2.2	-0.1	-0.5	-0.8	1.5	1.5	0.5	1.3	0.9
Alzheimer’s Disease (including proxy)	0.2	0.3	1.2	0.2	-0.4	-0.5	0.6	0.6	0.2	1.1	0.4
Crohns Disease (2017)	0.7	1.5	5.3	-1.1	-0.1	-0.4	-1.0	-1.1	-2.3	-0.9	-1.5
Irritable Bowel Disease (IBD)	0.6	1.3	3.7	-1.9	0.3	-1.2	-0.6	-0.7	-1.9	-0.6	-0.8
Ulcerative Colitis (UC)	0.4	0.8	1.8	-1.3	0.8	-1.1	-0.4	-0.5	-1.3	-0.4	-0.3
Major Depression (MDD)	2.6	3.2	7.2	0.7	-0.0	1.9	-1.9	-2.0	-1.4	-2.7	-2.1
Reaction Time	1.1	2.0	5.3	-1.0	-0.2	-0.8	1.7	1.4	1.4	2.3	1.5
Verbal and Numeric Reasoning (VNR)	7.6	18.4	27.0	3.0	4.5	4.0	-5.2	-5.1	-3.7	-3.0	-5.0
Breast Cancer	1.0	2.4	4.5	-0.6	-1.8	-0.1	1.9	1.8	2.1	0.7	2.0
Ovarian Cancer	0.8	1.1	2.6	-0.5	-1.4	-1.0	0.8	1.0	-0.2	1.6	1.2
Prostate Cancer	0.2	0.3	1.2	1.1	0.2	0.3	-0.3	-0.6	0.7	0.0	-0.4
Age at First Birth	1.0	1.4	2.7	-0.3	1.6	1.0	-1.3	-1.0	-1.6	-0.8	-1.2
Bipolar Disorder (2011)	0.7	0.7	5.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	-2.3
Body Mass Index (BMI) (2010)	0.7	1.0	3.0	1.7	1.1	1.5	0.2	-0.1	0.9	0.1	-0.4
Coronary Artery Disease (CAD)	3.4	4.0	18.2	-1.1	-0.2	-4.3	1.6	1.6	0.9	2.1	1.5
Crohns Disease (2012)	0.8	1.2	3.1	-1.5	0.3	-1.0	-0.6	-0.7	-1.8	-1.1	-1.1
Mean Putamen Volume	2.0	2.3	4.8	-2.2	-0.9	-1.8	1.2	1.4	0.1	2.1	1.3
Fasting Glucose	2.4	2.8	6.5	1.2	2.5	2.2	-1.3	-1.6	-1.0	-0.8	-2.0
HbA1C	0.5	0.6	1.9	0.2	-0.7	0.4	-0.7	-0.8	-0.6	-1.4	-0.7
HDL Cholesterol	1.5	2.4	10.2	0.3	1.0	3.2	-1.0	-0.9	-1.7	-1.6	-0.8
LDL Cholesterol	50.3	79.5	416.2	-4.3	-6.0	-20.4	6.6	6.7	2.6	5.4	6.4
Lupus	0.6	0.9	2.6	-0.1	-0.3	0.9	-1.6	-1.5	-0.8	-0.3	-1.1
Neuroticism (2016)	0.2	0.3	1.3	0.3	1.1	-0.4	-0.3	0.0	-0.4	-0.5	-0.3
Primary Biliary Cirrhosis	1.0	1.5	5.4	-0.5	1.1	-0.6	1.1	1.0	1.1	2.3	1.1
Rheumatoid Arthritis	0.5	0.7	1.8	-1.2	-0.6	-1.2	0.1	0.2	-1.3	-0.2	0.1
Schizophrenia (2014)	0.1	0.2	0.7	0.6	-0.6	0.8	-0.0	-0.2	0.5	-0.4	-0.2
Triglycerides	0.4	0.7	2.9	0.7	-1.7	-0.1	0.3	-0.0	1.3	0.4	-0.1
Type 2 Diabetes (T2D) (2012)	1.6	1.9	4.4	1.4	0.6	1.2	0.4	0.3	2.1	2.0	1.5
Ulcerative Colitis	1.4	2.0	9.9	-3.1	0.8	-1.8	0.9	0.7	0.3	0.5	0.9
Blood Eosinophil Count	0.6	4.4	6.8	2.6	1.9	1.4	-2.3	-2.4	-1.4	-2.1	-2.3
Blood Platelet Count	0.7	7.9	18.0	0.6	-2.9	-1.7	3.2	3.4	2.1	4.2	2.8
Blood Red Count	1.2	11.6	21.8	0.7	4.0	2.0	-4.1	-3.9	-4.7	-1.6	-4.1
Blood White Count	0.4	3.2	10.4	3.2	1.5	2.7	-0.2	-0.2	1.3	1.8	-0.3
Heel T-Score	1.4	11.4	34.2	0.5	3.2	5.8	-3.5	-3.8	-2.0	-2.0	-3.4
BMI	4.3	24.7	42.8	5.1	6.5	5.3	-5.2	-5.6	-2.5	-2.5	-5.5
Height	0.2	3.2	10.2	-0.7	-2.5	3.2	0.7	0.3	1.6	-2.3	0.3
Waist Hip Ratio (WHR)	0.2	0.9	1.6	-1.3	-1.1	1.1	-0.7	-0.7	-1.3	-0.5	-0.8
Systolic Blood Pressure	0.2	1.0	4.0	0.8	-0.7	-0.8	-1.1	-0.7	-2.0	-0.2	-1.0
Smoking Status	0.8	2.0	8.2	1.7	1.3	2.9	-0.6	-1.0	0.7	-0.5	-1.1
Allergy or Eczema	0.6	1.5	3.7	-0.6	1.9	0.7	-1.2	-1.0	-1.9	-0.2	-1.2
Cardiovascular Disease	1.3	4.4	30.4	0.1	-1.0	-5.5	-0.3	-0.1	-1.7	0.7	-0.0
Hypothyroidism (self reported)	0.4	0.9	1.4	0.7	1.2	0.3	-1.1	-1.1	-1.1	0.3	-1.1
Respiratory disease	3.6	8.0	12.0	2.0	2.2	3.5	-3.3	-3.2	-2.3	-2.4	-3.3
Type 2 Diabetes (T2D) (2018)	0.4	0.8	2.8	1.7	0.0	1.4	-0.5	-0.7	0.6	-0.1	-0.3
Lung FEV1/FVC ratio	0.2	1.1	6.6	-0.0	1.3	-2.6	-0.1	-0.0	-0.1	-0.2	-0.4
Lung FVC	0.0	0.2	0.8	-0.6	-0.2	0.3	0.2	0.7	-0.3	0.2	0.9
Neuroticism	1.9	4.6	13.5	1.7	3.7	1.8	-2.1	-2.1	-1.9	-0.3	-2.2
Chronotype (morning person)	2.9	6.7	24.5	-1.4	-3.2	0.6	-2.0	-2.0	-2.3	-4.9	-1.8
Hair Pigment	0.1	4.3	11.7	0.4	0.9	-1.3	2.2	2.2	2.3	3.4	2.2
Tanning	0.2	3.0	7.0	-0.1	0.5	1.4	-1.7	-1.5	-2.6	-2.6	-1.7
Hand grip strength (left)	0.3	0.8	2.8	0.0	-0.6	1.7	-0.7	-0.5	0.0	-1.6	-0.1
Number of treatments/medications taken	0.7	1.2	7.7	0.1	-0.6	-2.8	0.1	0.2	-0.6	1.1	0.1
Average weekly spirits intake	0.1	0.1	0.3	-0.0	-0.5	0.0	-0.2	-0.2	0.3	-0.3	-0.3
Sensitivity / hurt feelings	4.7	8.1	12.3	1.8	2.4	2.8	-3.1	-3.1	-2.4	-3.2	-3.5
Frequency of depressed mood in last 2 weeks	0.8	1.2	6.7	0.4	2.6	1.2	-0.6	-0.5	0.0	-0.1	-0.7
Hearing difficulty/problems: Yes	0.7	1.1	3.5	-0.6	0.8	1.4	0.8	0.5	1.2	1.9	0.7
Relative age of first facial hair	0.7	1.5	2.3	-1.4	-1.5	-1.1	1.3	1.4	0.5	0.9	1.4
Other serious medical condition/disability diagnosed by doctor	0.4	0.5	3.3	-0.1	0.8	-1.8	0.1	0.3	0.1	0.5	0.3
Ever used hormone-replacement therapy (HRT)	1.4	1.8	3.6	-1.7	-0.9	-0.5	1.4	1.2	1.1	1.9	1.3
Ever had hysterectomy (womb removed)	0.7	0.8	1.6	-1.3	-0.9	-0.5	0.9	1.0	0.8	0.2	1.2
Systolic blood pressure, automated reading	0.6	1.9	3.8	1.9	0.8	1.2	-1.7	-1.6	-1.1	-0.6	-1.5
Eye problems/disorders: Diabetes related eye disease	0.3	0.3	1.8	0.5	0.4	-0.1	-0.1	-0.3	0.3	1.4	0.3
Angina	1.7	2.2	16.3	-0.3	-0.4	-4.0	0.4	0.4	0.3	0.8	0.6
Medication for hormone replacement therapy	0.3	0.3	1.1	-1.1	-0.9	0.0	0.3	0.3	-0.0	-0.2	0.3
Vitamin and mineral supplements	0.7	1.0	2.0	-0.3	-1.4	-1.0	1.2	1.1	0.9	0.0	1.1
Supplements: Zinc	1.0	1.1	2.0	-0.3	1.4	1.4	-1.2	-1.0	-0.9	-0.8	-1.0
Medication: Co-codamol	0.3	0.4	0.8	0.4	0.6	-0.9	0.7	0.5	0.8	0.1	0.4
Medication: Metformin	1.0	1.4	4.3	1.2	-0.3	0.5	1.0	0.9	2.1	1.5	1.2
Diabetes (father)	0.8	1.0	2.2	-1.4	-0.9	0.7	1.1	0.9	0.6	-1.5	0.5
Diabetes (mother)	0.6	0.7	2.1	0.9	-0.6	1.4	0.4	0.2	1.5	0.5	0.6
Severe depression (siblings)	0.2	0.2	1.5	-0.3	1.2	-0.2	0.0	-0.0	-0.1	0.1	-0.0
Pack years adult smoking proportion	4.4	6.8	10.9	-1.9	-1.4	-1.9	3.2	3.0	3.0	2.4	3.3
Impedance of leg (right)	10.8	52.4	70.9	-5.4	-8.1	-7.6	8.3	8.4	5.8	5.2	8.2
Leg fat-free mass (left)	3.4	17.8	31.0	3.7	4.1	5.6	-4.5	-4.7	-2.2	-3.7	-4.5
Trunk fat percentage	0.7	2.7	8.6	1.5	1.4	-0.4	1.5	0.9	2.9	2.0	1.2
Hand grip strength (right)	0.3	0.7	2.2	-1.3	-0.3	1.3	-0.1	0.2	0.2	-1.5	0.4
Townsend deprivation index at recruitment	2.1	2.9	8.5	0.7	2.9	1.4	-2.0	-1.8	-1.2	-0.9	-1.6
Current tobacco smoking	1.4	2.3	5.7	0.5	-0.5	0.5	2.0	1.8	2.4	1.6	1.6
Average weekly fortified wine intake	1.7	1.9	4.0	2.0	-0.2	1.1	-1.5	-1.6	-0.8	-1.6	-1.5
Maternal smoking around birth	0.4	0.6	1.0	-1.0	0.4	-0.8	0.8	0.8	0.8	-0.3	0.8
Fed-up feelings	0.5	0.9	3.2	0.4	1.8	1.7	-0.1	-0.1	0.4	0.9	-0.3
Frequency of unenthusiasm / disinterest in last 2 weeks	0.6	0.8	2.8	1.4	1.7	0.4	-0.6	-0.8	0.1	0.4	-0.7
Relative age voice broke	1.5	2.2	3.4	0.9	1.2	1.3	-1.8	-1.6	-1.8	-1.2	-1.8
Taking other prescription medications	0.6	1.0	2.0	0.4	1.4	0.4	-1.2	-1.2	-0.8	0.1	-1.4
Age when periods started (menarche)	0.8	2.0	2.7	-1.2	-1.6	-1.1	1.5	1.5	1.5	1.0	1.6
Bilateral oophorectomy (both ovaries removed)	0.5	0.6	2.2	-1.0	-1.5	-0.9	0.5	0.5	0.2	-0.3	0.5
Heel bone mineral density (BMD) T-score, automated (left)	0.5	1.2	4.0	1.2	1.2	2.0	-1.1	-1.0	-0.5	0.1	-0.4
Tinnitus: Yes, but not now, but have in the past	0.9	0.9	3.0	-1.7	0.8	-0.2	0.7	0.7	1.3	0.6	1.0
Qualifications: CSEs or equivalent	0.9	1.2	4.0	0.1	-2.0	-1.9	0.9	0.8	0.4	-0.3	0.6
Serious illness, injury or assault to yourself	2.0	2.4	3.6	0.9	-1.6	-1.9	1.6	1.8	1.5	1.1	1.7
High blood pressure	0.5	1.5	2.5	1.5	0.7	1.1	-1.3	-1.2	-1.2	1.6	-1.0
Hayfever, allergic rhinitis or eczema	0.6	1.2	3.8	0.4	1.7	0.1	-0.9	-0.8	-1.9	0.0	-1.2
Multivitamins +/- minerals	2.9	3.6	7.3	-1.1	1.6	0.9	-2.2	-1.9	-2.7	-1.9	-2.2
Stomach or abdominal pain in last month	2.5	3.1	5.5	-1.5	-0.9	-1.7	2.3	2.3	1.9	0.4	2.1
Supplements: Glucosamine	2.9	3.8	7.7	-1.2	2.0	2.8	-1.8	-1.9	-1.6	-1.8	-2.1
Diverticular disease/diverticulitis (self-reported)	1.5	1.8	3.9	0.0	0.1	1.1	-1.5	-1.5	-1.4	-2.0	-1.6
Medication: Atenolol	0.6	0.7	4.9	0.1	-0.8	-2.2	0.2	0.3	-0.0	0.2	0.3
Medication: Levothyroxine sodium	0.2	0.4	1.5	1.2	-0.6	-0.3	-0.1	-0.2	-0.4	0.9	-0.4
Sitting height	0.2	1.4	3.7	1.2	-1.4	1.9	-0.2	-0.4	0.8	-1.9	-0.4
Chronic bronchitis/emphysema (father)	0.5	0.6	2.2	0.2	1.5	-0.0	-0.6	-0.4	-0.7	-1.1	-0.4
High blood pressure (mother)	2.1	2.9	4.6	1.9	1.9	0.5	-2.1	-2.1	-1.3	-1.0	-2.0
Body mass index (BMI)	2.6	10.9	25.4	3.8	5.0	3.3	-3.2	-3.6	-1.3	-1.1	-3.3
Impedance of leg (left)	11.4	55.5	75.5	-5.2	-7.7	-7.7	8.6	8.7	6.4	5.8	8.6
Leg predicted mass (left)	3.4	18.0	31.7	3.7	4.0	5.6	-4.5	-4.7	-2.2	-3.8	-4.5
Trunk fat mass	0.4	1.9	5.1	2.1	2.3	1.4	-0.1	-0.6	1.8	0.6	-0.2
Waist circumference	1.5	5.4	9.0	2.7	3.0	3.0	-2.3	-2.7	-0.5	-0.5	-2.3
Number of incorrect matches in round	0.1	0.2	1.0	0.0	1.0	-0.1	0.1	0.3	0.5	0.5	0.5
Past tobacco smoking	0.9	1.6	3.1	-1.0	-0.7	-1.3	1.6	1.8	0.7	1.2	1.6
Alcohol usually taken with meals	0.2	0.3	1.2	-0.4	-1.1	-0.3	-0.2	-0.3	-0.6	-0.2	-0.5
Nervous feelings	1.3	2.4	5.8	0.1	0.5	1.2	-1.6	-1.5	-1.7	-2.4	-2.0
Frequency of tenseness / restlessness in last 2 weeks	0.1	0.2	0.5	-0.6	0.3	-0.7	0.3	0.5	0.1	0.6	0.3
Hearing difficulty/problems with background noise	1.3	2.2	7.7	0.2	1.1	1.2	0.9	0.5	2.2	2.8	0.9
Hair/balding pattern: Pattern 2	0.6	0.7	1.2	0.4	-0.5	0.3	-1.1	-1.0	-1.0	-1.0	-1.0
Had menopause	0.4	0.5	1.9	-1.4	-0.6	0.8	0.5	0.4	0.6	0.3	0.6
Had other major operations	0.3	0.3	0.8	0.8	0.9	0.5	-0.5	-0.5	0.4	-0.1	-0.6
Forced vital capacity (FVC)	0.1	0.5	2.0	-1.4	-0.5	-0.4	0.4	0.8	-0.2	-0.7	0.8
Heel bone mineral density (BMD) T-score, automated (right)	0.4	0.9	4.5	-0.1	1.2	2.1	-0.8	-0.7	-0.1	-0.2	-0.1
Ever unenthusiastic/disinterested for a whole week	0.2	0.3	0.6	-0.7	0.0	-0.6	0.2	0.2	0.7	-0.7	0.1
Qualifications: None of the above	7.3	15.6	23.9	0.4	-2.9	-2.9	4.7	4.7	4.4	4.6	4.9
Financial difficulties in last 2 years	1.2	1.6	4.4	0.5	2.1	0.3	-1.5	-1.4	-1.3	-0.5	-1.5
Mouth/teeth dental problems	0.4	0.7	1.8	-0.7	1.4	0.4	-0.5	-0.4	-1.0	-1.1	-0.6
Heart attack	1.5	1.9	12.5	0.8	-0.1	-3.5	0.5	0.5	-0.2	1.2	0.5
Allergy	0.6	1.4	3.9	-0.8	-2.0	-0.8	1.0	0.9	1.5	0.3	1.2
Pain all over the body in last month	0.4	0.4	1.0	0.4	0.7	0.3	-1.0	-1.0	-0.0	-0.4	-0.8
Diabetes (self-reported)	0.9	1.4	7.3	2.7	-0.1	0.8	0.2	-0.0	1.2	1.2	0.2
Hayfever/allergic rhinitis (self-reported)	0.3	0.5	2.2	-0.6	0.5	0.3	-0.2	0.0	-1.5	-0.7	-0.5
Medication: Ramipril	1.2	1.5	6.2	0.9	-1.3	-2.5	0.4	0.5	-1.8	0.4	0.3
Medication: Simvastatin	6.1	8.9	59.0	0.8	-2.4	-7.7	1.0	1.1	-0.5	1.5	1.4
Fluid intelligence score	8.4	17.5	24.5	3.5	4.1	3.7	-5.0	-4.9	-3.6	-3.4	-4.9
Illnesses of siblings	0.9	1.2	4.0	-0.9	0.5	1.4	-0.7	-0.4	-1.2	-2.0	-0.7
Neuroticism score	1.6	3.4	7.1	1.4	2.7	1.8	-1.9	-1.8	-1.6	-1.0	-2.1
Weight	1.6	7.9	15.5	3.4	3.6	3.9	-2.5	-2.9	-0.2	-1.5	-2.6
Impedance of arm (right)	7.3	34.1	49.0	-3.4	-5.6	-6.0	7.0	6.8	6.3	4.0	6.5
Arm fat percentage (right)	0.6	2.5	10.2	2.2	3.2	0.8	-0.2	-0.7	1.7	0.7	-0.4
Trunk fat-free mass	3.1	17.6	36.5	2.6	3.1	6.0	-4.7	-4.7	-2.9	-4.0	-4.5
Hip circumference	0.6	2.7	7.5	2.7	2.6	1.7	-0.7	-1.1	1.2	0.3	-0.9
Time employed in main current job	1.0	1.2	2.0	-0.8	-0.0	-1.3	1.2	1.2	0.5	1.4	1.3
Alcohol intake versus 10 years previously	2.6	3.9	11.6	-0.6	3.4	1.7	-1.9	-1.9	-2.1	-0.9	-2.1
Father’s age at death	6.0	8.1	20.3	1.2	2.5	4.5	-2.9	-3.0	-2.3	-2.5	-2.9
Worrier / anxious feelings	0.7	1.3	3.0	0.9	1.0	1.7	-0.8	-0.9	-0.4	-1.4	-1.4
Frequency of tiredness / lethargy in last 2 weeks	1.0	1.6	7.7	-0.3	2.8	-0.1	-0.9	-0.8	-1.3	-0.9	-0.9
Falls in the last year	3.1	4.2	8.5	-0.1	-1.2	-0.7	2.3	2.1	2.9	2.6	2.6
Hair/balding pattern: Pattern 3	1.4	2.1	5.4	-2.3	-0.5	0.6	-1.3	-1.2	-1.8	-1.7	-1.1
Number of live births	4.3	6.1	12.1	1.0	-2.4	-1.1	2.4	2.4	3.5	2.9	3.0
Forced expiratory volume in 1-second (FEV1)	0.2	0.6	1.7	-1.3	-0.5	-1.1	0.5	0.9	-0.1	-0.6	0.8
Pulse rate	0.6	1.0	2.3	-1.5	-1.2	-1.3	0.0	0.2	-1.4	-0.9	-0.3
Happiness	0.4	0.5	2.0	-0.7	1.4	0.5	-0.5	-0.4	-0.5	-0.7	-0.6
Noisy workplace	6.4	7.9	13.5	-2.5	-0.5	-1.9	3.4	3.5	2.6	3.1	3.7
Qualifications: A levels/AS levels or equivalent	2.5	5.5	12.5	0.4	0.9	1.6	-2.7	-2.5	-2.7	-3.5	-2.6
Serious illness, injury or assault of a close relative in last 2 years	1.3	1.5	5.6	-0.8	2.4	-0.3	-1.1	-0.9	-1.8	-0.3	-0.8
Mouth/teeth dental problems: Dentures	0.1	0.2	0.9	0.6	-0.2	0.4	-0.2	-0.4	-0.3	1.0	0.1
Asthma	2.1	4.1	6.7	0.4	1.2	1.8	-2.3	-2.5	-2.2	-2.2	-2.6
Medication: Ibuprofen (e.g. Nurofen)	0.4	0.5	2.8	-0.9	1.7	0.2	0.3	0.3	0.6	0.2	0.2
Medication: Cholesterol lowering	9.5	14.7	102.0	-0.6	-2.4	-10.1	1.4	1.6	-1.0	1.1	1.8
Depression (self-reported)	0.3	0.4	1.4	0.8	0.1	0.6	0.5	0.5	1.2	0.4	0.5
Medication: Lansoprazole	1.5	1.8	2.7	-1.0	-1.4	-1.0	1.5	1.6	1.6	-0.3	1.6
Prospective memory result	0.6	0.7	2.7	0.5	-1.0	1.6	-0.4	-0.5	-0.3	-0.8	-0.6
Lung cancer (father)	1.5	1.7	3.5	-0.5	-1.4	-0.1	1.6	1.6	1.9	0.3	1.7
Illnesses of mother	2.0	2.5	5.6	-1.4	-1.8	0.0	1.9	1.8	2.4	0.4	1.4
Forced expiratory volume in 1-second (FEV1), Best measure	0.0	0.2	0.5	-0.5	0.2	0.2	-0.5	-0.3	-0.3	-0.7	-0.3
Pulse wave Arterial Stiffness index	0.5	0.6	1.2	0.5	-0.0	-0.3	1.0	0.9	1.1	0.9	0.6
Impedance of arm (left)	5.5	25.4	37.7	-2.9	-4.9	-5.4	6.1	5.9	5.2	3.3	5.6
Arm fat mass (right)	1.4	5.6	15.2	3.1	3.9	2.7	-1.8	-2.2	0.4	-0.6	-1.9
Trunk predicted mass	3.2	18.0	37.2	2.6	3.2	6.1	-4.7	-4.7	-2.9	-4.0	-4.5
Standing height	0.2	2.3	5.8	-0.5	-2.4	2.0	1.1	0.8	2.0	-1.2	1.0
Length of working week for main job	2.2	2.4	4.6	0.3	1.1	0.6	-1.9	-2.0	-2.0	-1.2	-2.1
Exposure to tobacco smoke at home	0.6	0.7	2.3	0.3	0.9	-0.6	0.8	0.8	1.5	0.1	0.8
Breastfed as a baby	0.5	0.6	1.1	0.7	1.0	1.0	-1.0	-0.8	-0.7	0.1	-0.6
Tense / ‘highly strung’	1.2	2.0	3.1	0.2	1.6	0.3	-1.8	-1.7	-1.5	-1.5	-1.7
Seen doctor (GP) for nerves, anxiety, tension or depression	1.1	1.6	5.6	0.1	1.1	0.7	-1.1	-1.2	-1.0	-2.4	-1.4
Hair/balding pattern: Pattern 4	0.2	0.4	0.7	-0.2	-0.1	-0.6	0.8	0.6	0.9	0.4	0.8
Birth weight of first child	4.9	8.9	15.4	0.6	0.3	2.8	-3.3	-3.4	-3.7	-3.9	-3.5
Peak expiratory flow (PEF)	1.2	2.7	8.2	-1.7	-2.9	-1.5	1.3	1.6	1.1	-0.8	1.4
Pulse wave reflection index	0.4	0.5	1.2	-0.3	0.4	-0.1	0.8	0.6	1.1	0.9	0.8
Ever highly irritable/argumentative for 2 days	1.0	1.1	2.0	0.3	1.4	1.2	-1.1	-1.2	-0.6	-0.7	-1.4
Loud music exposure frequency	0.2	0.2	0.7	-0.2	-0.8	0.4	-0.1	-0.2	0.7	-0.0	0.1
Qualifications: O levels/GCSEs or equivalent	2.8	4.4	9.3	0.4	1.4	1.2	-2.4	-2.3	-2.4	-3.0	-2.4
Mouth/teeth dental problems: Bleeding gums	0.8	1.1	3.7	0.5	-1.9	-0.9	0.8	1.0	1.0	0.7	0.9
Blood clot in the leg (DVT)	0.3	0.4	1.1	-0.8	1.1	0.4	0.3	0.1	0.7	0.7	0.5
Medication: Paracetamol	0.4	0.6	2.4	0.7	-1.1	-0.0	0.6	0.6	1.6	-0.2	0.5
Headache pain in last month	0.7	1.3	2.4	-1.6	0.2	-1.3	1.1	1.3	0.8	0.9	1.3
Medication for cholesterol, blood pressure or diabetes	2.5	4.1	26.7	-0.9	1.4	5.2	0.1	-0.0	1.7	-0.5	-0.2
Glaucoma (self-reported)	0.3	0.3	0.8	0.1	0.3	0.9	-0.6	-0.7	-0.8	0.2	-0.5
Gout (self-reported)	0.2	0.2	1.2	-0.4	0.2	1.1	-0.3	-0.5	-0.0	0.3	-0.1
Hypothyroidism/myxoedema (self-reported)	0.1	0.2	0.4	0.0	0.4	0.2	-0.4	-0.4	-0.6	0.4	-0.6
Medication: Amlodipine	0.9	1.3	5.8	0.1	-2.4	-1.4	0.6	0.5	-0.4	1.2	0.4
Medication: Ventolin 100micrograms inhaler	3.4	4.4	8.5	1.0	1.7	2.9	-2.3	-2.5	-1.7	-1.5	-2.4
Birth weight	2.9	6.3	9.8	3.1	1.3	1.4	-2.8	-2.9	-2.5	-2.8	-2.6
Chronic bronchitis/emphysema (mother)	1.5	1.8	4.8	-1.1	-0.7	-2.2	1.2	1.3	-0.1	1.3	1.7
High blood pressure (siblings)	0.4	0.6	1.9	0.2	1.1	-1.4	-0.3	-0.3	-0.2	1.0	-0.2
Forced vital capacity (FVC), Best measure	0.1	0.3	0.9	0.0	-0.3	1.0	-0.6	-0.3	-0.4	-0.9	-0.3
Body fat percentage	0.7	2.7	7.7	1.3	1.9	-0.4	1.4	0.9	2.8	2.1	1.2
Leg fat percentage (right)	0.7	2.6	6.7	0.6	1.3	-0.8	1.5	1.1	2.4	2.6	1.5
Arm fat-free mass (right)	3.1	16.0	34.0	3.0	3.2	5.8	-4.4	-4.5	-2.5	-3.5	-4.2
Exposure to tobacco smoke outside home	2.3	3.1	7.8	0.2	0.5	-0.5	1.9	1.9	2.3	2.8	1.9
Comparative body size at age 10	5.9	16.3	39.3	6.3	4.2	3.9	-3.9	-4.2	-2.0	-1.6	-4.3
Number of full brothers	3.6	4.5	13.5	0.2	-0.8	-0.7	2.5	2.0	3.7	2.1	2.6
Worry too long after embarrassment	0.3	0.5	1.9	0.6	1.4	0.8	-0.4	-0.4	-0.2	0.3	-0.5
Seen a psychiatrist for nerves, anxiety, tension or depression	0.5	0.6	2.2	1.1	0.0	0.5	-0.7	-0.6	-0.5	-1.5	-0.6
Wheeze or whistling in the chest in last year	0.9	1.6	3.3	1.1	1.8	1.8	-1.2	-1.2	-0.7	-0.9	-0.9
Number of children fathered	1.3	1.4	5.2	-0.7	-2.3	-1.4	1.1	1.1	0.8	-0.1	1.0
Reason for reducing amount of alcohol drunk: Health precaution	2.9	3.4	6.6	1.1	0.2	0.6	-2.1	-2.0	-2.5	-2.6	-2.1
Age at first live birth	1.0	1.7	5.3	-1.2	0.6	0.4	-0.8	-0.8	-2.3	-1.8	-1.4
Pulse wave peak to peak time	0.6	0.7	1.3	-0.5	0.2	0.6	-1.1	-1.0	-1.1	-1.0	-0.7
Health satisfaction	0.2	0.3	0.8	-0.8	-0.3	-0.9	-0.0	-0.0	0.3	-0.8	0.0
Shortness of breath walking on level ground	0.3	0.4	1.4	-0.9	0.0	-0.5	0.4	0.4	1.2	-0.0	0.7
Qualifications: College or University degree	6.5	20.5	31.0	2.3	3.4	4.5	-5.4	-5.3	-4.6	-4.3	-5.6
Eye problems/disorders: None of the above	2.3	2.7	6.1	1.8	2.5	1.1	-1.5	-1.2	-0.9	-2.0	-1.6
Mouth/teeth dental problems: Loose teeth	0.5	0.6	1.3	-0.0	0.7	0.0	-1.1	-1.0	-1.1	0.1	-1.0
Emphysema/chronic bronchitis	0.2	0.2	1.2	1.1	0.2	0.1	0.2	0.3	-0.2	0.6	0.3
Medication for pain relief, constipation, heartburn	1.4	2.3	7.1	0.3	0.8	2.7	-1.3	-1.3	-1.3	-1.9	-1.5
Neck or shoulder pain in last month	7.1	10.1	13.9	-1.5	-2.5	-3.7	3.7	3.7	3.1	2.9	3.6
Medication: Blood pressure	1.2	2.1	5.9	2.0	-0.1	-0.2	-1.7	-1.5	-2.4	0.3	-1.4
Angina (self-reported)	2.0	2.6	18.4	-0.1	-0.6	-4.3	0.5	0.6	0.4	0.9	0.7
Migraine (self-reported)	0.6	0.7	3.2	-0.0	-1.8	-1.3	0.4	0.2	-0.3	-0.6	0.1
Medication: Ibuprofen	0.2	0.2	0.7	-0.8	0.8	0.5	0.1	0.0	0.3	-0.2	0.1
Medication: Allopurinol	1.1	1.5	2.4	-0.5	1.4	1.6	-1.3	-1.4	-1.2	-0.6	-1.3
Medication: Omeprazole	0.3	0.4	0.8	0.4	0.2	-0.8	0.4	0.4	0.9	0.8	0.3
Medication: Seretide 50 evohaler	0.3	0.4	1.3	0.9	-0.2	1.1	-0.3	-0.4	-0.1	-0.8	-0.4
Mean time to correctly identify matches	1.4	2.7	8.5	-1.4	0.1	-0.6	1.8	1.4	1.6	2.9	1.6
Heart disease (mother)	0.6	0.7	3.3	0.2	-1.1	-1.8	0.3	0.4	-0.5	0.5	0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.5	0.6	1.5	0.5	-0.3	-1.2	0.9	1.0	0.3	0.3	1.1
Whole body fat mass	0.5	2.2	6.8	2.2	2.6	1.5	-0.1	-0.6	1.7	0.7	-0.2
Leg fat mass (right)	0.5	2.0	6.8	2.1	2.6	1.4	-0.4	-0.8	1.2	0.8	-0.4
Arm predicted mass (right)	3.2	16.4	33.8	2.9	3.3	5.8	-4.4	-4.5	-2.7	-3.5	-4.3
Pulse rate, automated reading	1.1	3.6	8.6	-2.0	-2.1	-2.9	1.8	1.8	0.2	1.6	1.7
Alcohol intake frequency.	0.5	1.2	2.7	0.7	0.6	-0.1	-1.4	-1.4	-1.6	0.1	-1.3
Comparative height size at age 10	0.2	0.9	2.3	-0.4	-0.5	1.2	1.1	1.1	1.5	-0.0	1.0
Number of full sisters	1.1	1.3	2.0	0.5	-1.0	-1.2	1.4	1.4	1.1	1.1	1.2
Suffer from ‘nerves’	0.2	0.4	1.5	-0.2	-1.2	-0.4	0.6	0.8	0.2	-0.5	0.4
Overall health rating	0.2	0.3	0.8	0.9	0.6	-0.8	-0.1	-0.1	0.5	0.9	-0.1
Chest pain or discomfort	1.6	2.3	5.3	0.1	-1.0	-2.3	1.4	1.4	1.8	1.4	1.7
Had major operations	0.5	0.6	2.1	-0.8	0.9	-1.4	0.3	0.3	0.5	0.7	0.5
Age at last live birth	1.2	1.7	4.4	-0.3	0.8	0.2	-1.2	-1.3	-2.1	-1.5	-1.8
Family relationship satisfaction	0.9	1.1	4.3	-1.5	2.1	-0.4	-0.7	-0.6	-0.8	0.5	-0.5
Leg pain on walking	2.5	3.1	6.7	-0.6	-1.4	-0.6	1.9	1.8	2.2	2.6	1.8
Qualifications: NVQ or HND or HNC or equivalent	2.5	3.0	4.1	-1.5	-1.6	-1.8	1.9	1.9	1.4	1.6	2.0
Commuting to job workplace: Car/motor vehicle	1.6	1.9	3.0	-0.9	-0.9	-1.3	1.7	1.6	1.6	1.3	1.4
Illness, injury, bereavement, stress in last 2 years	0.9	1.1	5.7	-0.2	-2.4	-0.1	1.1	0.8	0.7	0.4	0.5
Medication: Aspirin	3.7	4.9	20.5	0.4	-2.8	-4.5	1.4	1.4	0.4	2.0	1.6
Supplements: Vitamin C	0.5	0.6	2.7	0.7	0.7	1.7	-0.1	-0.2	0.5	1.0	0.1
Knee pain experienced in last month	0.5	0.8	2.0	-0.6	-0.0	-0.3	1.1	0.9	1.4	1.0	1.1
Hypertension (Self-reported)	0.5	1.3	3.3	1.5	0.3	0.7	-1.1	-1.0	-1.2	1.8	-0.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.9	1.0	1.7	-1.3	0.2	-1.2	1.3	1.2	0.4	0.9	1.0
Illnesses of father: Heart disease	2.7	3.7	12.7	-0.5	2.2	-3.6	-1.4	-1.3	-2.3	-0.9	-1.4
Illnesses of siblings: Diabetes	2.5	3.0	5.7	-0.0	-2.3	-0.7	1.9	1.7	2.4	1.6	2.0
Smoking status: Previous	1.9	2.8	5.2	0.9	1.2	1.1	-2.2	-2.3	-1.7	-1.4	-2.0
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.6	2.2	0.7	-0.2	1.5	-0.4	-0.6	-0.0	-1.3	-0.3
Whole body fat-free mass	3.4	19.7	38.8	3.2	3.8	6.2	-4.8	-4.9	-2.7	-4.0	-4.7
Leg fat-free mass (right)	3.7	19.6	34.5	3.9	4.4	5.9	-4.7	-4.9	-2.3	-3.8	-4.7
Arm fat percentage (left)	0.8	3.1	12.4	2.6	3.5	1.2	-0.6	-1.1	1.2	0.4	-0.9
Average weekly red wine intake	0.6	0.9	2.7	-0.6	-0.7	-1.6	0.8	0.9	1.0	0.4	1.1
Handedness (chirality/laterality): Left-handed	0.8	0.9	2.0	-0.2	0.9	0.9	-1.4	-1.4	-0.7	-0.8	-1.0
Mood swings	1.2	2.2	11.5	0.6	3.4	1.2	-0.9	-0.8	-0.8	1.1	-1.1
Loneliness, isolation	1.0	1.4	4.0	2.0	1.6	0.7	0.2	-0.1	0.6	1.9	-0.1
Long-standing illness, disability or infirmity	0.4	0.6	1.4	1.2	1.1	-0.2	0.3	0.2	1.1	0.9	0.2
Ever had bowel cancer screening	0.1	0.2	0.7	-0.3	0.4	-0.4	-0.2	-0.3	-0.2	0.8	-0.3
Diabetes diagnosed by doctor	0.9	1.4	7.5	2.7	0.3	1.1	-0.2	-0.4	1.1	1.0	-0.1
Ever had stillbirth, spontaneous miscarriage or termination	2.8	3.0	6.6	1.4	-0.2	-0.5	1.5	1.8	2.5	2.6	1.9
Friendships satisfaction	0.3	0.4	1.3	-0.4	1.2	-0.2	-0.6	-0.6	-0.7	-0.2	-0.8
Qualifications: nursing, teaching	1.3	2.0	3.7	1.3	0.6	1.1	-1.9	-1.9	-1.4	-1.2	-1.5
Commuting to job workplace: Walk	3.0	3.2	7.0	1.1	1.1	0.1	-2.2	-1.9	-2.0	-2.7	-1.9
Eye problems/disorders: Cataract	2.4	2.8	7.4	-2.1	-2.7	-1.2	1.5	1.2	0.8	1.5	1.4
Mouth/teeth dental problems: Mouth ulcers	0.5	0.8	1.4	-1.1	-0.5	-1.2	1.1	0.8	0.8	-0.1	0.8
Medication for cholesterol	2.2	3.3	15.1	1.2	1.6	3.9	-1.4	-1.2	-0.4	-1.5	-1.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.7	0.8	1.6	0.7	0.2	0.9	-0.8	-1.0	-0.5	-1.1	-1.3
Back pain experienced in last month	2.8	4.2	7.5	0.2	-1.4	-1.4	2.5	2.5	2.7	2.0	2.4
Mineral and other dietary supplements	0.6	0.8	4.8	2.2	-0.5	-0.4	0.3	0.3	0.7	0.1	0.5
Breast cancer (self-reported)	0.4	0.4	1.6	0.3	-0.3	-0.5	-0.8	-0.7	-0.6	-1.3	-0.3
Asthma (self-reported)	2.1	4.1	6.6	0.5	1.2	1.7	-2.3	-2.4	-2.2	-2.4	-2.6
Osteoporosis (self-reported)	1.6	2.0	3.0	1.7	-1.2	-1.1	0.9	1.3	1.4	1.7	1.7
Osteoarthritis (self-reported)	0.7	0.9	4.0	0.1	1.5	2.0	-0.5	-0.7	0.7	0.1	-0.2
Medication: Aspirin	3.9	5.1	21.9	0.3	-3.0	-4.7	1.4	1.4	0.3	1.9	1.5
Medication: Gliclazide	0.9	1.0	4.2	2.1	1.1	0.7	0.1	0.1	1.2	0.4	0.2
Illnesses of father: None of the above (group 1)	2.3	2.9	8.5	-0.0	-2.9	0.9	1.4	1.4	2.1	1.5	1.7
Smoking status: Current	2.1	3.4	8.4	0.6	-1.2	0.5	2.4	2.2	2.9	1.5	1.9
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.6	1.3	4.0	0.1	0.8	-0.7	-1.6	-1.2	-2.0	-0.4	-1.1
Whole body water mass	3.5	20.1	38.4	3.2	3.8	6.2	-4.9	-5.0	-2.8	-4.2	-4.8
Leg predicted mass (right)	3.5	18.7	33.8	3.9	4.3	5.8	-4.6	-4.8	-2.1	-3.6	-4.5
Arm fat mass (left)	1.3	5.3	14.8	3.0	3.8	2.6	-1.7	-2.1	0.4	-0.7	-1.9
Number of self-reported non-cancer illnesses	0.4	0.7	2.4	0.6	1.0	-1.6	-0.2	-0.3	-0.5	1.2	-0.4
Average weekly champagne plus white wine intake	2.1	2.9	4.6	0.8	0.9	2.0	-1.9	-1.9	-1.3	-2.1	-2.0
Miserableness	0.6	1.1	2.2	-0.9	0.6	-1.1	1.4	1.5	0.7	0.8	1.1
Guilty feelings	1.2	1.9	3.6	1.5	1.9	0.7	-1.5	-1.4	-1.4	-0.5	-1.4
Wears glasses or contact lenses	0.3	0.4	1.0	-0.2	-0.5	0.6	-0.6	-0.7	-0.6	-1.0	-0.6
Ever taken oral contraceptive pill	1.1	1.2	3.0	-0.3	1.7	0.6	-1.2	-1.3	-1.2	-0.6	-1.1
Hearing aid user	1.1	1.2	2.2	1.1	0.4	-0.1	1.2	1.2	1.3	1.5	1.4
Mother’s age at death	1.9	2.4	4.6	2.1	2.1	1.8	-1.3	-1.6	-0.4	-0.7	-1.5
Financial situation satisfaction	0.4	0.5	1.9	-1.4	1.1	-0.3	0.4	0.4	0.7	0.5	0.5
Tinnitus: Yes, now most or all of the time	0.5	0.6	1.3	1.1	-0.0	-1.1	-0.4	-0.2	-1.0	0.9	-0.4
Commuting to job workplace: Public transport	1.9	2.2	3.5	0.5	1.4	1.1	-1.7	-1.4	-1.8	-1.9	-1.6
Eye problems/disorders: Glaucoma	0.1	0.2	0.5	-0.6	0.1	0.7	-0.4	-0.5	-0.4	-0.0	-0.1
Medication: Blood pressure	0.4	0.8	3.0	0.6	-1.0	-0.8	0.7	0.5	0.4	1.7	0.4
Pain type(s) experienced in last month: Hip pain	0.6	0.8	2.0	0.6	-0.0	0.3	0.9	0.8	1.4	1.3	0.7
Supplements: Fish oil (including cod liver oil)	1.0	1.3	4.6	-2.1	0.5	0.7	-0.9	-0.9	-1.3	-0.8	-1.0
High cholesterol (Self-reported)	11.5	20.3	136.9	-1.2	-3.0	-11.7	1.6	1.9	-0.4	2.0	2.3
Medication: Bendroflumethiazide	0.5	0.7	2.6	1.6	-1.0	0.7	0.3	0.2	-0.2	1.2	0.0
Medication: Paracetamol	0.2	0.4	2.0	0.1	-1.4	0.2	0.0	0.0	0.8	-0.6	-0.0
Medication: Lisinopril	1.1	1.4	2.7	1.3	0.7	0.4	-1.4	-1.6	-1.3	-0.1	-1.6
Medication: Atorvastatin	8.9	10.9	57.3	-2.4	-2.5	-7.6	2.2	2.3	0.8	1.7	2.2
Illnesses of father: High blood pressure	1.9	2.4	3.7	1.8	1.4	0.6	-1.8	-1.9	-1.4	-1.5	-1.5
Alcohol drinker status: Never	0.2	0.3	1.2	0.2	-1.1	0.2	0.1	0.3	0.4	0.5	0.6
Ever smoked	2.5	4.3	7.2	1.1	2.5	2.2	-2.5	-2.7	-1.2	-1.1	-2.4
Basal metabolic rate	2.9	16.0	32.0	3.2	3.8	5.7	-4.3	-4.4	-2.0	-3.5	-4.2
Leg fat percentage (left)	0.8	2.9	7.5	0.9	1.8	-0.5	1.4	1.0	2.6	2.7	1.4
Arm fat-free mass (left)	2.7	13.5	28.1	2.7	3.2	5.3	-4.0	-4.1	-2.2	-3.1	-3.9
Number of operations (self-reported)	0.3	0.5	1.1	0.1	-0.8	-0.7	0.4	0.6	1.0	0.8	0.5
Average weekly beer plus cider intake	2.7	3.9	5.9	-0.8	-1.6	-1.8	2.3	2.4	1.9	2.0	2.4
Irritability	1.7	2.8	4.0	-0.3	1.9	0.7	-1.9	-1.9	-1.9	-1.9	-2.0
Risk taking	0.3	0.4	1.6	0.5	0.5	1.3	-0.3	0.1	0.1	1.1	0.3
Ever had prostate specific antigen (PSA) test	0.1	0.1	0.4	-0.6	-0.6	-0.5	0.2	0.2	0.2	0.2	0.1
Fractured/broken bones in last 5 years	1.6	2.0	5.8	-1.1	-2.4	-1.4	1.3	1.5	0.8	0.7	1.5
Age started oral contraceptive pill	0.5	0.6	2.3	-1.0	0.2	-0.0	0.5	0.5	0.8	1.5	0.7
Diastolic blood pressure, automated reading	0.1	0.4	1.7	1.1	0.1	1.3	-0.5	-0.3	-0.3	0.0	-0.3
Ever depressed for a whole week	1.4	1.7	5.9	-0.8	1.8	0.1	-1.0	-1.1	-0.6	-2.4	-1.1
Unable to work because of sickness or disability	0.2	0.3	0.8	0.9	0.4	-0.6	-0.4	-0.4	-0.2	0.7	-0.3
Commuting to job workplace: Cycle	0.6	0.8	1.7	1.2	-0.1	1.3	-1.0	-0.9	0.0	0.8	-0.6
Myopia	4.3	6.2	9.5	2.6	2.4	2.0	-2.6	-2.6	-2.4	-1.9	-3.1
Vascular/heart problems diagnosed by doctor	0.4	1.0	2.3	-1.3	-0.7	-0.0	1.0	0.9	1.2	-1.5	0.8
Cholesterol lowering medication	7.7	11.3	56.6	-0.6	-2.8	-7.5	2.1	2.1	1.1	3.1	2.5
Medication: Omeprazole (e.g. Zanprol)	0.3	0.4	1.0	0.2	0.3	-0.9	0.4	0.5	0.6	1.0	0.5
Pain experienced in last month	2.2	3.7	5.7	1.7	0.7	1.3	-2.3	-2.4	-2.2	-1.8	-2.3
Supplements: Calcium	0.3	0.3	0.8	-0.1	-0.3	-0.9	0.4	0.5	-0.6	0.8	0.2
Basal cell carcinoma (self-reported)	0.7	0.8	3.3	0.9	1.8	-0.0	-0.3	-0.1	-0.0	1.5	0.1
Heart attack/myocardial infarction (self-reported)	1.6	2.1	13.1	0.7	-0.3	-3.6	0.6	0.6	-0.0	1.3	0.6
Deep venous thrombosis (DVT) (self-reported)	0.5	0.6	1.0	-1.0	1.0	0.1	0.6	0.5	0.8	0.9	0.8
Heart disease (siblings)	2.8	3.5	6.6	1.5	-1.5	-2.6	1.5	1.2	2.3	2.2	1.8
Alcohol drinker status: Previous	1.1	1.2	3.2	-0.1	-0.6	-1.1	-1.1	-1.2	-1.8	-0.8	-1.3
Pack years of smoking	4.0	5.8	9.3	-1.6	-1.2	-1.5	3.0	2.8	2.8	2.4	3.1
Impedance of whole body	8.9	45.1	63.2	-3.9	-6.9	-7.0	8.0	7.9	6.3	5.1	7.6
Leg fat mass (left)	0.6	2.5	8.4	2.2	2.9	1.6	-0.5	-1.0	1.3	0.7	-0.5
Arm predicted mass (left)	2.8	14.2	31.5	3.0	3.3	5.6	-4.0	-4.2	-2.0	-3.1	-3.9