[Hub]/) : Traits : Leg predicted mass (right) :

chr19:9,709,433-11,459,260

Best TWAS P=2.16e-14 · Best GWAS P=6.58e-14 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Esophagus Mucosa SLC44A2 0.13 0.00 lasso 6 0.02 1.4e-02 4.3 -5.3 1.1e-07 -0.46 0.08 0.50 FALSE
2 GTEx Esophagus Mucosa ILF3-AS1 0.11 0.00 lasso 4 0.00 2.5e-01 7.4 -5.4 5.4e-08 -0.77 0.03 0.79 FALSE
3 GTEx Muscle Skeletal SLC44A2 0.19 0.18 lasso 5 0.19 5.1e-18 6.7 7.1 8.7e-13 0.79 0.68 0.32 FALSE
4 GTEx Nerve Tibial ILF3-AS1 0.14 0.04 lasso 3 0.08 3.8e-06 7.4 -5.9 2.9e-09 -0.77 0.02 0.96 FALSE
5 GTEx Testis PDE4A 0.20 0.02 enet 39 0.04 6.4e-03 5.1 6.0 2.0e-09 0.06 0.06 0.04 TRUE
6 GTEx Whole Blood CTD-2369P2.8 0.12 0.11 lasso 3 0.10 9.2e-10 4.9 5.5 4.6e-08 0.06 1.00 0.00 FALSE
7 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma LOC147727 0.13 0.02 blup 28 0.04 7.2e-05 7.4 -5.4 6.4e-08 -0.76 0.01 0.84 FALSE
8 The Cancer Genome Atlas Brain Lower Grade Glioma FDX1L 0.06 0.00 blup 53 0.02 5.1e-03 -3.4 -5.2 2.0e-07 0.05 0.00 0.20 TRUE
9 The Cancer Genome Atlas Brain Lower Grade Glioma LOC147727 0.07 0.02 lasso 2 0.02 5.4e-03 7.4 -7.6 2.2e-14 -0.99 0.02 0.79 TRUE
10 The Cancer Genome Atlas Thyroid Carcinoma SLC44A2 0.32 0.22 enet 14 0.25 3.8e-24 7.4 6.0 1.7e-09 0.85 0.02 0.98 FALSE