TWAS hub - FDX1L

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Kidney Renal Clear Cell Carcinoma	0.0629	0.0294	0.0013	0.024	0.013	0.029	NA	0.040	0.00085	0.0120	0.00031	NA	2.4e-05
2	TCGA	Brain Lower Grade Glioma	0.0629	0.0310	0.0021	-0.002	0.016	0.010	NA	0.000	0.72000	0.0051	0.02200	NA	3.5e-01
3	TCGA	Thyroid Carcinoma	0.0680	0.0330	0.0081	-0.003	0.007	0.002	NA	-0.003	0.99000	0.0560	0.20000	NA	9.5e-01

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Lupus	8.0	12.1	18.1	4.2	4.2	1.0
Rheumatoid Arthritis	7.1	9.8	14.8	3.5	3.8	1.6
Allergy	6.0	13.8	19.6	-3.7	-4.4	-2.8
Arm fat-free mass (right)	5.7	29.1	40.4	-5.4	-6.4	-4.2
Allergy or Eczema	5.6	14.8	24.9	3.9	5.0	2.0
Asthma	5.6	11.0	12.3	3.3	3.5	3.1
Asthma (self-reported)	5.5	10.9	11.8	3.4	3.4	3.0
Arm predicted mass (right)	5.3	27.3	36.9	-5.3	-6.1	-4.1
Arm fat-free mass (left)	5.3	26.8	35.7	-5.3	-6.0	-4.1
Whole body fat-free mass	5.1	29.3	36.0	-5.5	-6.0	-4.6
Trunk predicted mass	5.0	28.4	33.6	-5.8	-5.7	-4.4
Whole body water mass	5.0	28.4	35.3	-5.5	-5.9	-4.5
Hayfever, allergic rhinitis or eczema	4.9	10.6	18.7	3.0	4.3	2.0
Trunk fat-free mass	4.9	28.4	33.8	-5.8	-5.7	-4.3
Basal metabolic rate	4.9	27.1	34.4	-5.4	-5.9	-4.3
Arm predicted mass (left)	4.9	24.8	32.8	-5.1	-5.7	-4.0
Leg fat-free mass (left)	4.6	24.2	31.6	-4.8	-5.6	-4.2
Respiratory disease	4.5	10.0	11.5	3.1	3.4	3.0
Chronic bronchitis/emphysema (father)	4.4	5.2	11.6	0.9	1.8	3.4
Leg predicted mass (left)	4.4	23.3	29.9	-4.8	-5.5	-4.2
Mean Putamen Volume	4.3	5.0	6.1	-1.7	-2.5	-2.5
Medication: Gliclazide	4.3	4.8	5.6	-2.3	-2.4	-1.9
Angina	4.0	5.2	8.9	3.0	2.3	1.3
Ever had bowel cancer screening	4.0	4.6	7.9	2.8	2.3	0.8
Leg predicted mass (right)	4.0	21.5	27.1	-4.5	-5.2	-4.2
Smoking status: Previous	3.9	5.9	8.0	-2.8	-2.4	-1.9
Leg fat-free mass (right)	3.9	20.8	26.5	-4.4	-5.2	-4.1
Average weekly champagne plus white wine intake	3.5	4.8	6.2	-2.5	-2.0	-2.0
Lung FEV1/FVC ratio	3.4	17.1	21.3	-3.9	-4.6	-3.8
Weight	3.4	16.9	23.3	-4.2	-4.8	-3.1
Exposure to tobacco smoke at home	3.4	3.8	7.1	-1.7	-2.7	-1.2
Worry (Nagel 2018)	3.3	6.9	11.0	2.9	3.3	1.1
Number of full brothers	3.2	4.0	5.3	-2.3	-1.2	-2.3
Angina (self-reported)	3.2	4.2	7.3	2.7	2.0	1.2
Number of full sisters	3.2	3.9	6.8	-1.6	-1.5	-2.6
Impedance of arm (right)	3.1	14.4	24.3	3.4	4.9	2.7
Hip circumference	3.1	13.6	17.7	-4.1	-4.2	-2.4
Leg fat mass (right)	3.0	11.5	19.5	-3.3	-4.4	-2.1
Past tobacco smoking	2.9	5.4	7.0	2.6	2.0	2.2
Pulse wave reflection index	2.9	3.6	4.2	-2.1	-1.8	-1.8
Illnesses of father: High blood pressure	2.9	3.6	5.7	-1.8	-2.4	-1.3
BMI	2.8	16.3	26.0	-4.2	-5.1	-2.3
Health satisfaction	2.8	3.6	7.9	-0.9	-1.4	-2.8
Taking other prescription medications	2.7	4.1	6.2	2.0	2.5	1.5
Impedance of arm (left)	2.7	12.4	20.7	3.2	4.5	2.5
Length of working week for main job	2.7	3.0	5.1	-2.3	-1.7	-1.0
Arm fat mass (left)	2.7	11.0	17.3	-3.0	-4.2	-2.6
Financial difficulties in last 2 years	2.6	3.5	5.3	-2.1	-2.3	-0.8
Breastfed as a baby	2.6	3.3	5.0	-2.2	-1.9	-1.1
Leg fat mass (left)	2.6	10.1	17.6	-3.0	-4.2	-2.0
Impedance of whole body	2.5	12.7	18.7	3.2	4.3	3.0
Crohns Disease (2017)	2.4	5.3	11.4	-0.4	-2.1	-3.4
Verbal and Numeric Reasoning (VNR)	2.4	5.6	8.3	-2.6	-1.4	-2.9
Breast Cancer	2.4	5.8	8.1	2.7	2.8	1.4
Prostate Cancer	2.4	3.4	5.5	-1.5	-2.4	-1.6
Age when periods started (menarche)	2.4	5.7	9.5	-3.1	-1.8	-2.1
Happiness	2.4	2.9	3.6	-1.9	-1.4	-1.8
Heart disease (mother)	2.4	2.9	5.2	1.6	1.0	2.3
Age started oral contraceptive pill	2.4	3.0	4.5	2.1	1.9	0.8
Medication: Atenolol	2.3	2.9	4.5	-1.8	-2.1	-1.0
Mouth/teeth dental problems: Bleeding gums	2.3	2.9	5.1	-2.3	-1.4	-1.4
Waist circumference	2.2	8.2	13.4	-2.8	-3.7	-1.9
Medication: Seretide 50 evohaler	2.1	2.4	4.2	0.7	2.0	1.6
Ever used hormone-replacement therapy (HRT)	2.0	2.5	4.7	2.2	1.7	0.4
Tinnitus: Yes, but not now, but have in the past	2.0	2.1	2.8	-1.5	-1.1	-1.7
Hair/balding pattern: Pattern 2	2.0	2.5	3.7	1.9	1.9	0.4
Arm fat mass (right)	2.0	8.4	13.8	-2.6	-3.7	-2.1
Eye problems/disorders: None of the above	2.0	2.3	4.3	-2.1	-1.0	-1.2
Emphysema/chronic bronchitis	2.0	2.2	4.1	2.0	1.3	1.0
Depression (Nagel 2018)	1.9	2.9	6.5	1.2	2.5	0.8
Primary Biliary Cirrhosis	1.9	2.7	4.7	2.2	1.6	-0.8
Body mass index (BMI)	1.9	8.3	15.4	-2.5	-3.9	-1.9
Neck or shoulder pain in last month	1.9	2.6	3.7	1.5	1.9	1.4
Whole body fat mass	1.9	7.8	12.8	-2.6	-3.6	-1.9
Forced expiratory volume in 1-second (FEV1), predicted	1.9	3.9	8.2	-2.9	-1.5	-1.1
Eye problems/disorders: Cataract	1.9	2.2	5.9	2.4	0.7	0.4
Fractured/broken bones in last 5 years	1.9	2.4	5.7	-2.4	-1.2	0.3
Irritable Bowel Disease (IBD)	1.8	4.3	9.3	-0.5	-1.8	-3.0
Type 2 Diabetes (T2D) (2018)	1.8	3.4	6.4	-1.5	-2.5	-1.3
Current tobacco smoking	1.8	2.9	5.5	1.6	2.4	0.7
Multivitamins +/- minerals	1.8	2.2	4.4	-2.1	-1.2	-0.9
Impedance of leg (left)	1.8	8.8	11.2	2.4	3.4	3.1
Had menopause	1.8	2.2	4.8	2.2	1.2	0.5
Mouth/teeth dental problems	1.8	2.8	3.1	1.6	1.8	1.6
Forced expiratory volume in 1-second (FEV1), Best measure	1.8	5.7	6.7	-2.4	-2.6	-2.2
Hayfever/allergic rhinitis (self-reported)	1.7	2.3	5.1	0.8	2.3	1.0
Shortness of breath walking on level ground	1.7	2.0	3.1	1.4	1.8	1.0
Financial situation satisfaction	1.7	2.1	3.3	-1.8	-1.7	-0.1
Average weekly fortified wine intake	1.6	1.8	4.0	0.6	1.0	2.0
Trunk fat mass	1.6	7.1	11.3	-2.5	-3.4	-1.9
Tense / ‘highly strung’	1.6	2.7	5.0	2.2	1.7	-0.3
Hand grip strength (right)	1.5	4.0	5.2	-1.4	-2.3	-2.2
Worrier / anxious feelings	1.5	2.7	6.3	1.2	2.5	0.7
Medication: Amlodipine	1.5	2.1	4.6	2.1	0.7	1.2
Birth weight	1.5	3.2	7.8	-0.9	-1.0	-2.8
Intelligence (Savage-Jansen 2018)	1.4	4.3	6.8	-2.5	-0.2	-2.6
Impedance of leg (right)	1.4	6.6	8.5	1.7	2.9	2.9
Relative age voice broke	1.4	2.1	2.8	-1.7	-1.5	-1.2
Hearing difficulty/problems with background noise	1.4	2.2	3.9	-1.4	-1.0	-2.0
Depression (self-reported)	1.4	1.7	2.6	1.1	1.6	1.2
Blood clot in the leg (DVT)	1.4	1.9	3.9	2.0	0.9	0.9
Medication: Ventolin 100micrograms inhaler	1.4	1.8	2.6	1.6	0.9	1.4
Exposure to tobacco smoke outside home	1.4	1.9	4.5	-0.0	-2.1	-1.1
Medication: Paracetamol	1.4	2.1	4.5	-0.8	-1.2	-2.1
Ever depressed for a whole week	1.4	1.7	3.1	0.2	1.8	1.4
Neuroticism (Nagel 2018)	1.3	3.0	4.9	2.0	2.2	0.4
Chronotype (morning person)	1.3	2.9	6.7	-0.4	-1.4	-2.6
Seen doctor (GP) for nerves, anxiety, tension or depression	1.3	1.9	4.6	0.9	2.1	0.6
High blood pressure (siblings)	1.3	1.8	3.4	1.9	1.3	0.6
Age at last live birth	1.3	1.9	3.2	0.9	1.3	1.8
Diabetes diagnosed by doctor	1.3	2.1	3.5	-1.2	-1.9	-1.2
Commuting to job workplace: Walk	1.3	1.4	2.4	-0.7	-1.2	-1.5
Mouth/teeth dental problems: Mouth ulcers	1.3	2.1	2.3	-1.4	-1.5	-1.5
Medication for cholesterol	1.3	2.0	4.0	0.2	2.0	1.4
Mother’s age at death	1.3	1.6	4.0	0.4	2.0	0.8
Crohns Disease (2012)	1.2	1.9	5.2	0.2	-0.7	-2.3
Neuroticism	1.2	2.8	4.4	1.9	2.1	0.5
Relative age of first facial hair	1.2	2.4	3.3	-1.4	-1.4	-1.8
Alcohol usually taken with meals	1.2	1.9	2.6	-1.0	-1.5	-1.6
Diabetes (self-reported)	1.2	1.9	4.0	-0.9	-2.0	-1.0
Falls in the last year	1.2	1.6	3.2	0.4	1.8	1.2
Forced expiratory volume in 1-second (FEV1)	1.2	4.0	5.3	-2.0	-2.3	-1.7
Diastolic blood pressure, automated reading	1.2	3.7	9.0	-0.5	-3.0	-1.3
Alzheimer’s Disease (in mother)	1.1	1.3	2.9	0.0	1.0	1.7
Supplements: Zinc	1.1	1.1	3.0	-1.7	-0.6	0.2
Qualifications: CSEs or equivalent	1.1	1.4	2.8	-0.5	-1.7	-1.0
Illnesses of mother	1.1	1.4	3.5	-0.6	-0.5	-1.9
Birth weight of first child	1.1	2.0	3.7	-1.5	-0.3	-1.9
Headache pain in last month	1.1	1.9	3.2	1.1	1.8	1.1
Wheeze or whistling in the chest in last year	1.1	2.0	2.9	0.8	1.7	1.6
Medication: Aspirin	1.1	1.4	2.0	1.4	0.9	1.1
Wears glasses or contact lenses	1.1	1.2	2.8	0.3	1.7	0.9
Myopia	1.1	1.5	2.0	-1.2	-1.1	-1.4
Blood White Count	1.0	7.7	16.9	-0.3	-2.5	4.1
Medication: Co-codamol	1.0	1.2	2.1	-1.5	-1.0	-0.6
Stomach or abdominal pain in last month	1.0	1.2	2.2	-0.5	1.0	1.5
Standing height	1.0	9.8	15.4	-3.9	-2.4	-2.9
Peak expiratory flow (PEF)	1.0	2.3	4.3	-1.1	-2.1	-1.2
Leg fat percentage (right)	1.0	3.6	7.5	-1.7	-2.7	-0.6
Leg pain on walking	1.0	1.2	3.2	-0.1	-1.8	-0.6
Commuting to job workplace: Car/motor vehicle	1.0	1.1	2.5	-0.9	-0.2	1.6
Arm fat percentage (left)	1.0	4.0	7.5	-1.7	-2.7	-1.3
Friendships satisfaction	1.0	1.2	1.8	-1.4	-1.1	-0.7
Vitamin and mineral supplements	0.9	1.2	2.2	1.5	0.6	1.0
Medication: Metformin	0.9	1.2	2.5	-0.6	-1.6	-0.9
Frequency of unenthusiasm / disinterest in last 2 weeks	0.9	1.2	2.8	0.4	1.7	0.9
Prospective memory result	0.9	1.1	3.3	1.8	0.3	0.0
Forced vital capacity (FVC), Best measure	0.9	3.4	4.4	-2.0	-2.1	-1.4
Reason for reducing amount of alcohol drunk: Health precaution	0.9	1.0	2.4	1.6	0.7	0.5
Illnesses of father: Heart disease	0.9	1.3	1.7	1.2	1.3	1.0
Handedness (chirality/laterality): Left-handed	0.9	1.1	2.0	-0.6	0.9	1.4
Long-standing illness, disability or infirmity	0.9	1.4	2.4	1.4	1.6	0.3
Alzheimer’s Disease (including proxy)	0.8	1.2	2.6	0.3	1.6	0.9
Ovarian Cancer	0.8	1.0	1.2	1.1	0.9	1.0
Systolic Blood Pressure	0.8	4.1	11.0	3.3	0.4	1.1
Sitting height	0.8	5.4	6.7	-2.6	-2.0	-2.3
Arm fat percentage (right)	0.8	3.3	6.2	-1.6	-2.5	-1.2
Medication: Paracetamol	0.8	1.3	3.1	-0.6	-0.6	-1.8
Smoking status: Current	0.8	1.2	2.7	1.0	1.7	0.1
Number of self-reported non-cancer illnesses	0.8	1.4	2.2	1.2	1.5	0.6
Guilty feelings	0.8	1.2	2.1	1.5	0.5	-1.1
Medication: Bendroflumethiazide	0.8	1.2	3.0	-0.5	-1.7	-0.4
Ever smoked	0.8	1.4	2.3	-1.1	-0.7	-1.5
Leg fat percentage (left)	0.8	2.8	6.5	-1.4	-2.5	-0.5
Ever had prostate specific antigen (PSA) test	0.8	0.9	1.5	1.1	1.2	0.5
Deep venous thrombosis (DVT) (self-reported)	0.8	1.0	2.1	1.4	0.5	0.8
Schizophrenia (2018)	0.7	1.5	2.8	-0.7	-1.1	-1.7
Ulcerative Colitis (UC)	0.7	1.3	2.6	-0.7	-0.9	-1.6
Frequency of depressed mood in last 2 weeks	0.7	1.0	2.9	-0.0	1.7	0.4
Ever had hysterectomy (womb removed)	0.7	0.8	2.0	1.4	0.7	-0.3
Medication for hormone replacement therapy	0.7	0.8	1.8	0.1	-0.7	-1.4
Pain all over the body in last month	0.7	0.7	1.5	0.6	0.5	-1.2
Fluid intelligence score	0.7	1.4	2.6	-1.2	-0.2	-1.6
Father’s age at death	0.7	1.0	2.2	0.7	1.5	0.4
Medication: Ibuprofen (e.g. Nurofen)	0.7	0.9	1.4	-1.0	-0.3	-1.2
Lung cancer (father)	0.7	0.8	1.1	1.1	0.8	0.9
Pulse wave Arterial Stiffness index	0.7	0.8	1.8	-0.5	-0.5	-1.4
Comparative body size at age 10	0.7	2.1	3.6	-1.6	-1.9	0.3
Worry too long after embarrassment	0.7	1.2	2.2	1.5	1.2	0.0
Mouth/teeth dental problems: Loose teeth	0.7	0.8	1.5	-1.2	-0.9	-0.4
Loneliness, isolation	0.7	0.9	2.0	0.3	1.4	0.9
Osteoarthritis (self-reported)	0.7	0.9	1.6	0.6	0.8	1.3
Medication: Lisinopril	0.7	0.9	1.8	0.5	-1.4	-0.7
Basal cell carcinoma (self-reported)	0.7	0.8	1.9	1.4	0.6	0.5
Fasting Glucose	0.6	0.7	1.4	0.2	-1.2	-0.8
Systolic blood pressure, automated reading	0.6	1.7	4.5	2.1	-0.2	0.8
Serious illness, injury or assault to yourself	0.6	0.7	1.2	-0.1	1.0	1.1
Number of incorrect matches in round	0.6	1.0	2.0	-0.5	-1.4	-0.9
Heart attack	0.6	0.8	1.2	0.7	1.1	0.8
Neuroticism score	0.6	1.3	2.3	1.2	1.5	0.5
Ever highly irritable/argumentative for 2 days	0.6	0.7	2.1	-0.2	-0.0	-1.4
Chronic bronchitis/emphysema (mother)	0.6	0.7	0.8	0.6	0.9	0.9
Body fat percentage	0.6	2.4	4.8	-1.3	-2.2	-0.8
Eye problems/disorders: Glaucoma	0.6	0.8	1.5	1.2	0.9	0.0
Medication: Blood pressure	0.6	1.2	3.1	0.3	-1.8	-0.6
Alcohol drinker status: Previous	0.6	0.7	0.8	-0.9	-0.8	-0.9
Age at First Birth	0.5	0.7	1.4	0.1	-0.8	1.2
Blood Platelet Count	0.5	6.0	8.8	2.8	-1.2	-3.0
Number of treatments/medications taken	0.5	0.8	1.8	1.4	0.7	-0.5
Diabetes (mother)	0.5	0.7	1.0	-0.9	-1.0	-0.3
Severe depression (siblings)	0.5	0.5	1.2	0.6	1.1	0.3
Trunk fat percentage	0.5	1.9	4.0	-1.0	-2.0	-0.9
High blood pressure (mother)	0.5	0.7	1.2	0.9	0.1	1.1
Number of live births	0.5	0.7	1.1	-1.0	0.3	1.0
Qualifications: A levels/AS levels or equivalent	0.5	1.2	2.0	-1.2	-0.3	-1.4
Serious illness, injury or assault of a close relative in last 2 years	0.5	0.5	0.9	-0.9	0.7	0.6
Age at first live birth	0.5	0.9	1.1	1.0	1.0	0.7
Medication: Aspirin	0.5	0.7	1.3	1.1	0.7	0.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.5	1.0	2.0	-0.6	-1.4	-0.8
Pain experienced in last month	0.5	0.9	1.7	0.2	-1.3	-1.0
Supplements: Calcium	0.5	0.6	0.9	-0.9	0.1	-1.0
Heart attack/myocardial infarction (self-reported)	0.5	0.6	0.8	0.6	0.9	0.8
Pack years of smoking	0.5	0.7	1.2	0.9	1.1	-0.6
Bipolar Disorder or Schizophrenia	0.4	1.1	2.1	-0.4	-1.0	-1.4
LDL Cholesterol	0.4	0.7	1.3	0.6	1.1	0.6
Type 2 Diabetes (T2D) (2012)	0.4	0.5	0.9	0.0	0.7	0.9
Height	0.4	8.0	17.6	-4.2	-2.2	-1.2
Waist Hip Ratio (WHR)	0.4	1.9	4.3	2.1	0.3	1.2
Hand grip strength (left)	0.4	1.0	2.0	-0.5	-1.4	-0.9
Diabetes (father)	0.4	0.5	1.4	1.2	-0.2	-0.4
Diverticular disease/diverticulitis (self-reported)	0.4	0.5	1.0	0.3	-1.0	-0.6
Forced vital capacity (FVC)	0.4	1.6	2.1	-1.5	-1.3	-0.9
Mouth/teeth dental problems: Dentures	0.4	0.6	1.2	0.0	-0.8	-1.1
Medication: Lansoprazole	0.4	0.4	0.7	0.8	0.5	0.6
Hypothyroidism/myxoedema (self-reported)	0.4	0.9	2.0	1.4	-0.0	0.8
Pulse wave peak to peak time	0.4	0.5	1.3	0.2	0.3	1.1
Medication for pain relief, constipation, heartburn	0.4	0.7	1.8	0.4	0.2	1.4
Migraine (self-reported)	0.4	0.5	1.0	0.4	1.0	0.5
Medication: Ibuprofen	0.4	0.5	0.9	-0.6	-0.3	-1.0
Had major operations	0.4	0.5	1.4	-1.2	-0.1	0.2
Supplements: Vitamin C	0.4	0.4	0.6	-0.5	-0.8	-0.7
Knee pain experienced in last month	0.4	0.6	1.1	-1.0	-0.8	-0.3
Miserableness	0.4	0.6	1.4	-0.0	1.2	0.6
Supplements: Fish oil (including cod liver oil)	0.4	0.6	1.3	0.4	1.2	0.5
Average weekly beer plus cider intake	0.4	0.6	1.2	1.1	0.4	-0.7
Depressed Affect (Nagel 2018)	0.3	0.7	1.2	0.8	1.1	0.4
Alzheimer’s Disease (in father)	0.3	0.4	1.0	0.2	1.0	0.1
Body Mass Index (BMI) (2010)	0.3	0.4	1.0	-0.5	-1.0	-0.2
HDL Cholesterol	0.3	0.4	1.0	-0.5	0.1	1.0
Heel T-Score	0.3	2.2	5.9	2.4	0.8	0.3
Hypothyroidism (self reported)	0.3	0.7	1.8	1.4	-0.5	-0.0
Pack years adult smoking proportion	0.3	0.4	0.6	0.5	0.8	-0.5
Townsend deprivation index at recruitment	0.3	0.5	1.0	-1.0	-0.4	-0.4
Bilateral oophorectomy (both ovaries removed)	0.3	0.3	0.7	-0.2	0.5	-0.8
Nervous feelings	0.3	0.6	1.1	1.0	0.7	-0.5
Alcohol intake versus 10 years previously	0.3	0.5	0.9	-0.7	-0.4	-0.9
Qualifications: O levels/GCSEs or equivalent	0.3	0.5	0.9	-1.0	-0.7	-0.4
Glaucoma (self-reported)	0.3	0.3	0.9	0.3	1.0	-0.2
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.3	0.9	0.4	0.0	0.9
Number of children fathered	0.3	0.4	0.5	0.7	0.7	0.4
Comparative height size at age 10	0.3	1.6	2.4	-1.5	-1.2	-1.0
Overall health rating	0.3	0.7	1.2	-1.1	-0.9	-0.4
Chest pain or discomfort	0.3	0.4	1.1	-0.3	-0.3	-1.1
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.4	0.5	-0.6	-0.5	0.7
Illness, injury, bereavement, stress in last 2 years	0.3	0.4	0.7	-0.3	-0.7	-0.9
Hypertension (Self-reported)	0.3	0.7	1.1	1.1	-0.9	0.5
Ever had stillbirth, spontaneous miscarriage or termination	0.3	0.4	0.6	0.3	0.8	0.6
Qualifications: nursing, teaching	0.3	0.4	0.9	-0.9	0.2	-0.5
Illnesses of father: None of the above (group 1)	0.3	0.3	0.8	-0.9	-0.1	-0.3
Tinnitus: Yes, now most or all of the time	0.3	0.3	0.8	0.3	0.3	-0.9
Commuting to job workplace: Public transport	0.3	0.4	0.9	-0.1	0.9	-0.5
Medication: Atorvastatin	0.3	0.4	0.6	0.3	0.6	0.8
Medication: Omeprazole (e.g. Zanprol)	0.3	0.3	0.9	1.0	0.2	0.1
Schizophrenia vs Biploar Disorder	0.2	0.2	0.5	0.0	-0.4	-0.7
HbA1C	0.2	0.3	0.5	0.7	0.3	-0.4
Smoking Status	0.2	0.5	1.4	-1.2	-0.3	-0.5
Maternal smoking around birth	0.2	0.2	0.6	-0.1	0.8	-0.3
Fed-up feelings	0.2	0.4	0.7	0.5	0.8	0.4
High blood pressure	0.2	0.7	1.6	0.6	-1.3	0.3
Medication: Levothyroxine sodium	0.2	0.3	0.4	0.6	-0.5	0.3
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.3	1.0	-1.0	-0.2	-0.0
Ever unenthusiastic/disinterested for a whole week	0.2	0.2	0.4	-0.2	0.7	-0.4
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.3	0.5	-0.7	-0.5	-0.3
Hair/balding pattern: Pattern 3	0.2	0.3	0.5	0.1	0.5	0.7
Pulse rate	0.2	0.3	0.8	-0.9	-0.1	-0.5
Noisy workplace	0.2	0.2	0.3	0.5	0.3	0.5
Medication: Cholesterol lowering	0.2	0.3	0.7	-0.5	0.9	0.1
Gout (self-reported)	0.2	0.3	0.9	0.0	0.2	1.0
Medication: Allopurinol	0.2	0.3	0.5	0.3	0.4	0.7
Medication: Omeprazole	0.2	0.2	0.7	0.8	0.1	-0.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.2	0.2	0.4	0.6	0.4	-0.4
Alcohol intake frequency.	0.2	0.5	1.1	-0.1	-0.6	-1.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.2	0.2	0.6	0.3	0.7	-0.2
Illnesses of siblings: Diabetes	0.2	0.3	0.8	0.2	-0.9	0.2
Breast cancer (self-reported)	0.2	0.3	0.5	-0.5	0.2	-0.7
Osteoporosis (self-reported)	0.2	0.2	0.4	-0.2	-0.7	-0.3
Ever taken oral contraceptive pill	0.2	0.3	0.6	-0.8	-0.4	-0.1
Alcohol drinker status: Never	0.2	0.2	0.3	0.5	-0.2	-0.5
Number of operations (self-reported)	0.2	0.3	0.5	-0.7	0.6	-0.2
Irritability	0.2	0.4	0.8	-0.9	0.5	0.3
Risk taking	0.2	0.3	0.6	-0.3	0.4	-0.8
Unable to work because of sickness or disability	0.2	0.3	0.8	0.2	0.9	0.0
Commuting to job workplace: Cycle	0.2	0.3	0.4	0.6	-0.6	0.2
Heart disease (siblings)	0.2	0.2	0.5	0.7	0.2	-0.2
Bipolar Disorder (2018)	0.1	0.1	0.3	0.5	0.3	0.2
Neuroticism (2016)	0.1	0.2	0.3	0.6	0.2	-0.5
Triglycerides	0.1	0.1	0.3	0.5	0.2	0.1
Blood Eosinophil Count	0.1	1.1	1.9	1.4	0.8	0.8
Cardiovascular Disease	0.1	0.4	1.0	-0.2	-1.0	0.3
Lung FVC	0.1	0.5	0.9	0.9	-0.2	-0.7
Tanning	0.1	0.9	1.2	0.9	-1.1	-0.8
Average weekly spirits intake	0.1	0.2	0.4	-0.2	0.1	0.6
Sensitivity / hurt feelings	0.1	0.1	0.3	-0.4	0.1	0.5
Hearing difficulty/problems: Yes	0.1	0.1	0.3	-0.5	0.1	0.1
Eye problems/disorders: Diabetes related eye disease	0.1	0.1	0.1	-0.1	-0.4	-0.0
Supplements: Glucosamine	0.1	0.1	0.2	0.3	0.4	-0.2
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.2	0.4	0.6	-0.2	-0.5
Qualifications: None of the above	0.1	0.3	0.7	0.8	-0.3	0.0
Medication: Simvastatin	0.1	0.2	0.4	-0.0	0.6	-0.3
Illnesses of siblings	0.1	0.1	0.1	0.2	0.3	0.3
Time employed in main current job	0.1	0.2	0.3	-0.3	-0.3	-0.6
Hair/balding pattern: Pattern 4	0.1	0.2	0.2	0.3	-0.5	0.4
Qualifications: College or University degree	0.1	0.5	1.2	0.4	0.2	-1.1
Medication: Blood pressure	0.1	0.2	0.5	0.7	-0.5	-0.1
Suffer from ‘nerves’	0.1	0.2	0.3	-0.6	-0.2	-0.5
Family relationship satisfaction	0.1	0.1	0.3	-0.3	-0.0	-0.6
Average weekly red wine intake	0.1	0.1	0.3	-0.6	-0.1	0.2
Mood swings	0.1	0.2	0.4	0.1	0.6	0.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.1	0.2	0.3	-0.2	-0.4	-0.5
Mineral and other dietary supplements	0.1	0.2	0.4	0.3	-0.1	0.6
Pain type(s) experienced in last month: Hip pain	0.1	0.1	0.1	-0.2	0.4	0.1
High cholesterol (Self-reported)	0.1	0.2	0.5	-0.5	0.2	-0.7
Vascular/heart problems diagnosed by doctor	0.1	0.4	1.1	-0.3	1.0	-0.1
Cholesterol lowering medication	0.1	0.2	0.6	0.2	0.8	-0.1
Major Depression (MDD)	0.0	0.0	0.0	0.0	0.0	0.0
Reaction Time	0.0	0.0	0.0	0.1	-0.1	-0.2
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0
Coronary Artery Disease (CAD)	0.0	0.0	0.0	0.0	0.0	0.0
Schizophrenia (2014)	0.0	0.0	0.1	0.2	-0.2	0.1
Ulcerative Colitis	0.0	0.1	0.2	0.0	0.4	-0.2
Blood Red Count	0.0	0.2	0.4	0.4	-0.7	0.1
Hair Pigment	0.0	0.3	0.9	0.2	-0.1	-1.0
Other serious medical condition/disability diagnosed by doctor	0.0	0.0	0.1	-0.0	0.2	0.3
Heel bone mineral density (BMD) T-score, automated (left)	0.0	0.1	0.1	0.3	0.3	0.2
Had other major operations	0.0	0.0	0.0	-0.0	0.2	0.1
Medication: Ramipril	0.0	0.1	0.1	-0.3	0.1	0.2
Loud music exposure frequency	0.0	0.0	0.0	0.1	-0.0	-0.0
Medication for cholesterol, blood pressure or diabetes	0.0	0.0	0.1	0.1	-0.3	0.1
Mean time to correctly identify matches	0.0	0.1	0.2	0.1	0.4	0.1
Pulse rate, automated reading	0.0	0.1	0.2	-0.5	-0.3	-0.1
Back pain experienced in last month	0.0	0.1	0.2	-0.4	0.2	0.1
Hearing aid user	0.0	0.0	0.1	0.1	0.4	-0.1

Hub : Genes

FDX1L

Models

Trait associations