[Hub]/) : Traits : Leg predicted mass (right) : ← →

chr19:41,193,580-42,626,207

Best TWAS P=1.12e-09 · Best GWAS P=3.86e-08 conditioned to 0.494

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Aorta CTC-435M10.6 0.16 0.14 lasso 3 0.13 1.3e-07 5.4 5.2 1.8e-07 0.99 0.02 0.98 FALSE
2 GTEx Brain Cerebellar Hemisphere B3GNT8 0.38 0.30 lasso 5 0.23 1.1e-06 5.5 5.3 1.1e-07 0.99 0.01 0.98 FALSE
3 GTEx Brain Cerebellar Hemisphere CTC-435M10.6 0.29 0.20 lasso 4 0.18 2.6e-05 5.5 5.5 3.0e-08 1.00 0.01 0.96 FALSE
4 GTEx Brain Cerebellum B3GNT8 0.28 0.23 lasso 5 0.21 9.2e-07 5.5 5.3 1.0e-07 0.99 0.02 0.98 FALSE
5 GTEx Brain Cerebellum CTC-435M10.6 0.18 0.01 lasso 4 0.03 5.1e-02 5.2 5.6 2.4e-08 0.86 0.02 0.85 FALSE
6 GTEx Testis EXOSC5 0.31 0.33 enet 10 0.33 1.8e-15 5.0 5.1 3.1e-07 0.99 0.02 0.98 FALSE
7 The Cancer Genome Atlas Bladder Urothelial Carcinoma BCKDHA 0.02 0.02 lasso 2 0.02 1.5e-02 5.2 -5.1 2.8e-07 -0.98 0.01 0.79 FALSE
8 The Cancer Genome Atlas Brain Lower Grade Glioma ATP5SL 0.02 0.03 enet 4 0.02 7.0e-04 5.2 -5.1 2.7e-07 -0.98 0.02 0.88 FALSE
9 The Cancer Genome Atlas Brain Lower Grade Glioma EXOSC5 0.04 0.03 lasso 2 0.02 5.8e-03 5.5 5.4 5.3e-08 0.98 0.01 0.79 FALSE
10 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma ATP5SL 0.23 0.05 blup 18 0.05 4.5e-03 5.5 -6.0 2.3e-09 -0.90 0.01 0.83 FALSE
11 The Cancer Genome Atlas Prostate Adenocarcinoma ATP5SL 0.03 0.03 blup 18 0.03 4.1e-04 5.5 -5.3 1.5e-07 -0.98 0.01 0.92 FALSE
12 The Cancer Genome Atlas Rectum Adenocarcinoma B3GNT8 0.39 0.08 blup 20 0.07 1.1e-02 5.2 6.1 1.1e-09 0.84 0.00 0.29 TRUE