[Hub]/) : Traits : Leg predicted mass (right) : ← →

chr1:182,298,784-184,739,300

Best TWAS P=1.29e-09 · Best GWAS P=6.28e-11 conditioned to 0.0461

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex TSEN15 0.23 0.18 lasso 9 0.18 4.7e-21 6.2 6.1 1.3e-09 0.90 0.01 0.99 TRUE
2 GTEx Adipose Visceral Omentum RP11-181K3.4 0.13 0.06 lasso 3 0.14 8.3e-08 5.1 5.6 1.8e-08 0.04 0.04 0.96 TRUE
3 GTEx Artery Tibial LAMC1 0.10 0.10 lasso 5 0.10 2.2e-08 5.0 -5.2 2.6e-07 -0.03 0.06 0.94 FALSE
4 GTEx Artery Tibial RP11-181K3.4 0.07 0.07 lasso 15 0.05 1.1e-04 5.0 5.2 1.6e-07 0.06 0.06 0.93 FALSE
5 GTEx Brain Cerebellar Hemisphere LAMC1 0.50 0.16 enet 13 0.13 3.8e-04 5.1 5.1 2.8e-07 0.04 0.04 0.94 FALSE
6 GTEx Brain Cerebellar Hemisphere TSEN15 0.38 0.08 lasso 13 0.16 5.3e-05 6.2 5.8 4.9e-09 0.83 0.01 0.96 FALSE
7 GTEx Esophagus Muscularis RP11-181K3.4 0.05 0.09 lasso 1 0.07 3.9e-05 5.3 5.3 1.4e-07 0.03 0.04 0.95 FALSE
8 GTEx Nerve Tibial LAMC1 0.07 0.08 enet 30 0.05 1.1e-04 5.1 5.2 2.0e-07 0.07 0.03 0.96 FALSE
9 GTEx Nerve Tibial RP11-181K3.4 0.18 0.24 enet 30 0.24 2.9e-17 5.2 5.2 2.4e-07 0.03 0.03 0.97 FALSE
10 METSIM Adipose TSEN15 0.06 0.02 enet 28 0.04 1.3e-06 6.2 5.5 2.9e-08 0.76 0.01 0.99 FALSE
11 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma GLT25D2 0.05 0.01 enet 10 0.04 6.3e-05 3.0 -5.7 1.1e-08 -0.69 0.01 0.93 FALSE
12 The Cancer Genome Atlas Brain Lower Grade Glioma TSEN15 0.11 0.08 blup 52 0.10 6.7e-12 6.2 5.8 5.3e-09 0.78 0.01 0.99 FALSE