[Hub]/) : Traits : Leg predicted mass (right) : ← →

chr4:119,634,694-121,242,474

Best TWAS P=1.83e-08 · Best GWAS P=9.5e-08 conditioned to 0.643

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex PDE5A 0.05 0.04 lasso 2 0.03 8.1e-05 5.3 -5.3 1.4e-07 -0.94 0.05 0.94 FALSE
2 GTEx Artery Aorta RP11-33B1.1 0.12 0.10 lasso 8 0.13 2.0e-07 5.0 -5.2 2.1e-07 -0.90 0.10 0.88 FALSE
3 GTEx Artery Tibial RP11-33B1.4 0.14 0.10 lasso 7 0.06 8.5e-06 5.3 5.2 2.5e-07 0.89 0.01 0.99 FALSE
4 GTEx Brain Caudate basal ganglia RP11-33B1.1 0.27 0.34 lasso 2 0.29 5.9e-09 5.3 -5.3 8.6e-08 -0.94 0.03 0.97 FALSE
5 GTEx Brain Cerebellar Hemisphere RP11-33B1.1 0.35 0.34 lasso 8 0.33 2.5e-09 5.3 -5.4 8.5e-08 -0.91 0.02 0.98 FALSE
6 GTEx Brain Cerebellum RP11-33B1.1 0.31 0.30 lasso 11 0.32 2.9e-10 5.3 -5.3 1.5e-07 -0.89 0.05 0.95 FALSE
7 GTEx Brain Hypothalamus RP11-33B1.1 0.40 0.24 lasso 6 0.23 4.5e-06 5.3 -5.1 2.9e-07 -0.89 0.04 0.93 FALSE
8 GTEx Brain Putamen basal ganglia RP11-33B1.1 0.32 0.16 lasso 7 0.16 9.9e-05 5.3 -5.6 2.4e-08 -0.89 0.04 0.88 FALSE
9 GTEx Esophagus Muscularis RP11-33B1.1 0.10 0.14 lasso 3 0.12 1.4e-07 5.3 -5.2 1.7e-07 -0.93 0.04 0.95 FALSE
10 GTEx Heart Atrial Appendage RP11-33B1.1 0.15 0.08 lasso 3 0.10 4.0e-05 5.3 -5.3 1.1e-07 -0.95 0.03 0.97 FALSE
11 GTEx Heart Atrial Appendage RP11-33B1.4 0.12 0.10 lasso 4 0.05 2.0e-03 5.3 5.6 1.8e-08 0.91 0.06 0.86 TRUE