TWAS hub - PDE5A

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0470	0.0220	1.0e-04	0.037	0.028	0.017	0.029	0.032	2.2e-05	1.9e-04	2.9e-03	1.6e-04	8.1e-05
2	GTEx	Artery Aorta	0.1790	0.0590	2.8e-04	0.034	NA	0.107	NA	0.073	5.3e-03	NA	1.7e-06	NA	7.6e-05
3	GTEx	Artery Tibial	0.1038	0.0388	3.2e-03	0.014	NA	0.011	NA	0.034	2.5e-02	NA	4.1e-02	NA	1.0e-03
4	GTEx	Brain Caudate basal ganglia	0.1300	0.0580	2.2e-03	0.020	NA	0.065	NA	0.041	8.8e-02	NA	6.4e-03	NA	2.5e-02
5	GTEx	Cells EBV-transformed lymphocytes	0.2540	0.0790	1.2e-07	0.198	NA	0.167	NA	0.197	4.6e-07	NA	4.3e-06	NA	5.1e-07
6	GTEx	Thyroid	0.0930	0.0440	4.1e-03	0.043	NA	0.029	NA	0.038	2.8e-04	NA	2.6e-03	NA	6.9e-04
7	NTR	Blood	0.0256	0.0083	5.5e-12	0.045	0.039	0.041	0.040	0.042	2.2e-14	1.1e-12	4.4e-13	6.7e-13	2.0e-13
8	ROSMAP	Brain Pre-frontal Cortex	0.0249	0.0154	1.1e-02	-0.001	0.012	0.001	0.013	0.000	4.0e-01	9.7e-03	2.6e-01	7.3e-03	2.7e-01
9	TCGA	Kidney Renal Papillary Cell Carcinoma	0.1040	0.0760	5.4e-03	0.038	0.016	0.018	NA	0.039	3.0e-03	4.1e-02	3.3e-02	NA	2.6e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Impedance of leg (right)	13.5	65.4	106.1	9.8	0.8	2.2	9.6	10.3	7.3	9.2	8.9	8.5
Impedance of leg (left)	12.2	59.0	96.6	9.5	1.0	2.9	9.0	9.8	6.3	8.7	8.4	8.3
Impedance of whole body	9.2	46.6	75.9	8.3	0.5	2.0	8.6	8.7	5.4	8.0	7.3	7.0
Age at last live birth	5.2	7.5	12.9	3.3	-1.3	0.2	3.5	3.3	0.6	3.6	3.2	2.9
Impedance of arm (left)	4.9	22.8	43.5	5.7	-0.4	0.9	6.6	6.1	3.6	5.9	4.8	4.6
Impedance of arm (right)	4.7	21.8	36.2	5.5	-0.3	0.3	6.0	6.0	4.1	5.7	5.0	4.3
Ever had stillbirth, spontaneous miscarriage or termination	3.8	4.1	7.3	-2.2	0.2	-1.2	-2.7	-2.0	-2.6	-1.9	-2.4	-1.8
Ovarian Cancer	3.6	4.8	10.5	-1.6	-3.2	-3.1	-3.2	-0.6	1.9	-1.4	0.7	-1.9
Age at first live birth	3.6	6.4	10.0	3.1	-1.6	1.1	2.9	3.2	1.8	3.0	2.5	2.8
Angina (self-reported)	3.5	4.6	8.9	2.1	3.0	1.7	2.5	2.1	0.1	2.1	2.6	1.9
Angina	3.3	4.4	8.4	2.0	2.9	1.8	2.4	2.1	0.2	1.9	2.6	1.8
Had other major operations	3.3	4.0	6.7	-2.5	-1.3	0.6	-2.1	-2.1	0.7	-2.6	-2.2	-2.6
Leg predicted mass (right)	3.2	17.1	27.8	-5.3	-1.2	-0.9	-5.1	-5.1	-1.6	-4.7	-4.8	-4.9
Pain experienced in last month	3.2	5.3	9.1	2.6	1.0	-0.3	2.3	2.8	1.8	3.0	3.0	2.3
Blood White Count	3.1	22.9	41.0	5.9	0.7	3.0	5.7	5.7	0.9	5.2	5.2	6.4
Leg fat-free mass (right)	3.1	16.6	27.2	-5.2	-1.2	-0.9	-5.0	-5.0	-1.6	-4.7	-4.7	-4.9
Blood Platelet Count	3.0	35.2	56.1	7.2	1.1	2.4	7.0	7.5	-1.3	7.1	6.7	7.5
Pulse wave reflection index	3.0	3.6	8.4	-2.6	-0.6	0.5	-2.0	-2.9	0.0	-2.7	-1.7	-1.9
Age at First Birth	2.9	4.2	8.1	2.4	1.2	-0.7	2.4	2.4	1.0	2.7	2.8	1.7
Body Mass Index (BMI) (2010)	2.8	3.8	8.6	-2.1	-2.3	-0.9	-2.9	-2.0	0.7	-2.7	-1.1	-1.5
Birth weight of first child	2.8	5.0	11.4	-2.6	-0.5	0.1	-2.5	-3.1	-0.1	-3.4	-2.4	-2.2
Wheeze or whistling in the chest in last year	2.8	5.0	8.1	-2.5	-1.4	0.6	-2.7	-2.7	-1.8	-2.7	-2.8	-1.9
Pulse wave peak to peak time	2.7	3.2	8.8	2.0	0.7	-1.2	1.2	2.1	3.0	1.9	1.8	1.2
BMI	2.6	15.0	30.3	-4.7	-0.3	-0.7	-5.1	-5.1	-1.5	-5.5	-3.3	-4.0
Leg fat-free mass (left)	2.5	13.2	21.9	-4.7	-1.1	-1.0	-4.6	-4.5	-0.8	-4.2	-4.0	-4.4
Leg predicted mass (left)	2.5	13.3	22.1	-4.7	-1.1	-1.1	-4.6	-4.5	-0.7	-4.3	-4.0	-4.4
Knee pain experienced in last month	2.3	3.5	7.2	-2.7	-0.9	0.6	-1.9	-2.3	0.4	-2.5	-2.0	-2.1
Whole body water mass	2.2	12.6	22.5	-4.5	-1.3	-1.0	-4.7	-4.3	-0.8	-4.0	-4.0	-4.2
Diastolic blood pressure, automated reading	2.2	6.7	11.3	3.0	-1.6	0.4	2.0	3.3	-3.0	3.4	1.7	3.2
Systolic Blood Pressure	2.1	10.5	18.5	3.7	1.9	3.3	2.6	3.8	-2.2	3.3	3.2	4.3
Whole body fat-free mass	2.1	11.8	20.8	-4.4	-1.3	-1.0	-4.6	-4.1	-0.7	-3.9	-3.8	-4.1
Average weekly red wine intake	2.1	3.0	5.2	2.3	-0.1	0.7	1.8	2.3	-0.2	2.2	2.0	2.1
Handedness (chirality/laterality): Left-handed	2.1	2.5	5.4	-1.7	-1.1	-1.1	-2.3	-1.4	-0.7	-1.7	-1.9	-1.8
Medication: Atorvastatin	2.1	2.6	4.4	2.1	1.0	1.3	1.7	1.9	-1.3	1.9	1.2	1.9
Coronary Artery Disease (CAD)	2.0	2.4	5.4	1.7	1.0	1.7	2.3	1.7	-0.9	1.7	0.9	1.5
Body mass index (BMI)	2.0	8.4	15.9	-3.5	0.4	-0.5	-3.9	-3.9	-1.3	-4.0	-2.6	-2.8
Heart attack	2.0	2.5	4.9	1.7	1.3	-0.2	2.2	1.4	-1.1	1.8	2.0	1.7
Alcohol intake versus 10 years previously	2.0	3.0	7.2	-2.0	-0.5	-2.7	-1.2	-1.8	0.1	-0.9	-2.3	-2.0
Medication: Blood pressure	2.0	3.6	9.7	1.5	3.1	1.1	2.1	1.3	-2.0	2.0	2.0	1.2
Illnesses of father: Heart disease	2.0	2.7	4.3	1.6	2.0	1.5	1.7	1.7	-1.2	1.6	2.1	1.4
Illnesses of father: None of the above (group 1)	2.0	2.5	4.2	-1.6	-2.0	-1.6	-1.9	-1.4	0.3	-1.3	-1.8	-1.6
Wears glasses or contact lenses	2.0	2.3	5.4	-1.7	1.3	2.3	-1.7	-1.8	-0.5	-1.7	-1.0	-1.1
Average weekly fortified wine intake	1.9	2.2	3.9	1.7	0.8	1.5	1.3	1.8	0.4	1.3	2.0	1.8
Diverticular disease/diverticulitis (self-reported)	1.9	2.3	5.3	1.5	1.0	1.0	2.3	1.8	0.1	2.0	1.1	1.7
Medication: Cholesterol lowering	1.9	2.9	5.5	1.9	1.3	1.4	2.4	1.6	-1.5	2.0	1.6	1.4
Prospective memory result	1.9	2.3	3.8	-1.9	0.4	0.6	-2.0	-1.8	-0.4	-1.8	-1.7	-1.7
Pulse wave Arterial Stiffness index	1.9	2.2	7.8	-1.4	-0.5	1.5	-0.7	-1.6	-2.8	-1.4	-1.4	-0.7
Medication for cholesterol, blood pressure or diabetes	1.9	3.2	6.8	-1.5	-2.6	-0.5	-2.0	-1.4	2.2	-2.2	-1.8	-0.7
Neck or shoulder pain in last month	1.9	2.7	8.2	-1.6	0.3	2.9	-1.4	-1.7	0.3	-2.3	-1.5	-0.9
Townsend deprivation index at recruitment	1.8	2.5	5.4	-1.8	-1.2	0.3	-2.3	-2.0	0.3	-2.3	-1.4	-1.3
Noisy workplace	1.8	2.2	5.0	1.8	-0.4	-0.8	2.2	1.4	1.2	1.8	1.5	1.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.8	2.1	4.6	-1.9	0.1	1.5	-1.7	-1.6	0.5	-2.1	-0.9	-1.4
Back pain experienced in last month	1.8	2.6	4.7	-1.9	-0.7	-0.8	-1.4	-2.0	-1.0	-1.9	-1.8	-2.2
Heart attack/myocardial infarction (self-reported)	1.8	2.4	4.4	1.6	1.5	-0.1	2.1	1.2	-1.4	1.7	1.8	1.6
Crohns Disease (2012)	1.7	2.8	4.7	1.7	0.1	-0.5	2.2	2.1	1.7	1.9	2.1	1.5
Supplements: Glucosamine	1.7	2.2	3.8	-1.5	-2.0	0.5	-1.7	-1.1	1.6	-1.8	-1.6	-0.8
Trunk fat-free mass	1.7	9.6	17.3	-4.0	-1.4	-0.9	-4.2	-3.6	-0.3	-3.4	-3.5	-3.7
Falls in the last year	1.7	2.3	4.3	-1.9	-1.8	-1.3	-1.4	-1.3	1.6	-1.4	-0.8	-2.1
Trunk predicted mass	1.7	9.9	17.6	-4.0	-1.4	-1.0	-4.2	-3.7	-0.3	-3.4	-3.6	-3.8
Commuting to job workplace: Car/motor vehicle	1.7	2.0	3.9	-1.5	0.5	-1.0	-2.0	-1.5	-0.5	-1.7	-1.4	-1.8
Basal metabolic rate	1.7	9.2	16.4	-3.9	-1.2	-0.7	-4.0	-3.6	-0.2	-3.5	-3.3	-3.6
Alzheimer’s Disease (in mother)	1.6	1.9	4.0	2.0	-0.4	0.0	1.5	1.8	-0.5	1.9	1.1	1.5
HDL Cholesterol	1.6	2.6	5.6	1.8	-1.5	-1.2	1.8	2.0	-1.2	2.4	-0.6	1.3
Happiness	1.6	2.0	3.5	1.2	-0.3	-1.3	1.9	1.6	1.1	1.9	1.5	1.3
Blood clot in the leg (DVT)	1.6	2.0	4.5	1.9	0.2	0.6	1.6	1.5	-0.2	1.5	1.7	2.1
Qualifications: NVQ or HND or HNC or equivalent	1.6	1.9	5.3	-1.1	-1.7	-0.3	-1.9	-1.0	2.3	-1.6	-0.2	-0.9
Medication: Lisinopril	1.6	2.0	6.0	1.0	2.4	2.4	0.8	0.7	-0.7	0.6	1.3	1.3
Pack years of smoking	1.6	2.3	4.4	-1.9	-0.3	-0.1	-1.0	-1.8	-2.1	-1.4	-2.0	-1.5
Medication: Atenolol	1.5	1.8	4.5	1.1	2.1	1.6	1.3	0.9	-1.0	0.9	1.2	1.5
Illnesses of siblings	1.5	2.1	8.0	-0.1	-2.8	-2.7	-0.2	0.2	1.8	0.4	0.0	-0.2
Tense / ‘highly strung’	1.5	2.5	11.6	-0.6	3.4	2.3	0.6	-0.5	-2.0	-0.5	0.0	0.0
Commuting to job workplace: Walk	1.5	1.6	2.6	1.4	-1.4	1.3	1.3	1.4	-1.0	1.2	0.3	1.6
Osteoarthritis (self-reported)	1.5	1.9	7.4	-1.0	0.5	2.7	0.1	-0.8	-1.0	-1.1	-2.3	-0.6
Financial situation satisfaction	1.5	1.8	5.9	1.2	-2.0	-0.4	0.3	1.2	2.4	1.0	1.2	1.1
Risk taking	1.5	2.2	6.4	-1.3	-2.5	-1.1	-1.1	-1.3	-0.8	-0.8	-2.1	-1.3
Arm predicted mass (left)	1.5	7.4	15.4	-3.5	-0.7	-0.5	-3.9	-3.3	0.2	-3.2	-2.7	-3.1
Crohns Disease (2017)	1.4	3.0	7.3	1.7	-0.1	-1.0	1.9	2.2	2.7	1.6	1.8	1.1
Waist Hip Ratio (WHR)	1.4	6.1	26.7	1.5	-1.6	2.3	3.0	1.9	5.2	1.1	1.2	1.5
Ever used hormone-replacement therapy (HRT)	1.4	1.8	3.7	-1.9	-0.2	0.3	-1.4	-1.6	0.4	-1.6	-1.2	-1.7
Chronic bronchitis/emphysema (mother)	1.4	1.6	5.4	-1.5	-0.6	-1.4	-1.5	-1.1	-0.0	-1.0	-0.1	-2.3
High blood pressure (siblings)	1.4	2.0	10.9	-0.2	3.3	2.3	0.1	-0.4	-1.2	-0.6	0.1	-0.1
Arm fat-free mass (right)	1.4	7.1	13.2	-3.4	-0.9	0.3	-3.6	-3.2	-0.4	-3.2	-3.1	-2.8
Shortness of breath walking on level ground	1.4	1.7	8.4	0.2	1.7	1.8	-0.2	-0.4	-2.9	-0.3	-0.6	0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.4	1.6	3.8	1.1	1.3	1.9	0.6	1.1	0.3	1.1	1.5	1.6
Breast cancer (self-reported)	1.4	1.6	3.0	1.6	-1.0	-0.2	1.4	1.7	0.5	1.7	1.3	1.2
Number of self-reported non-cancer illnesses	1.4	2.4	10.0	-0.5	1.1	3.2	-0.2	-0.4	-3.0	-0.5	-0.5	-0.0
Supplements: Fish oil (including cod liver oil)	1.4	1.9	3.3	1.5	-1.4	1.2	1.0	1.8	1.2	1.2	0.8	1.8
Arm fat-free mass (left)	1.4	7.1	15.3	-3.3	-0.6	-0.3	-3.9	-3.2	-0.3	-3.2	-2.8	-3.0
Number of operations (self-reported)	1.4	2.1	4.2	-1.5	-0.0	1.8	-1.6	-1.6	-0.6	-2.1	-1.3	-1.4
Vascular/heart problems diagnosed by doctor	1.4	3.9	14.5	-0.9	-3.0	-2.3	-1.3	-0.7	3.8	-1.1	-0.8	-0.9
Medication: Omeprazole (e.g. Zanprol)	1.4	1.7	3.8	1.2	1.9	1.2	0.3	1.6	0.3	1.3	1.7	1.3
Basal cell carcinoma (self-reported)	1.4	1.7	3.3	-1.8	-0.3	-0.5	-1.6	-1.8	0.4	-1.7	-1.0	-1.4
Depression (Nagel 2018)	1.3	2.0	5.1	1.0	1.6	1.1	1.4	1.3	1.3	1.0	2.2	1.3
Bipolar Disorder (2011)	1.3	1.2	2.2	1.4	0.1	0.5	1.2	1.5	0.5	1.3	1.3	1.2
Cardiovascular Disease	1.3	4.2	10.4	1.7	2.9	1.8	1.3	1.5	-3.2	1.5	2.0	1.6
Chronotype (morning person)	1.3	3.0	6.7	-1.8	1.0	-0.9	-0.9	-2.2	-2.6	-1.5	-1.8	-2.0
Systolic blood pressure, automated reading	1.3	3.8	11.8	1.6	0.2	2.6	1.1	1.4	-3.4	1.5	1.1	2.5
Taking other prescription medications	1.3	1.9	9.0	0.8	1.5	3.0	1.0	0.8	-0.9	0.8	1.4	0.8
High blood pressure	1.3	3.7	12.8	0.8	3.0	2.6	1.1	0.6	-3.6	0.8	0.7	0.9
Heart disease (mother)	1.3	1.6	3.3	1.3	1.6	0.8	1.8	1.2	-1.1	1.5	0.0	1.0
Arm predicted mass (right)	1.3	6.7	13.8	-3.2	-0.8	-0.1	-3.7	-3.1	-0.4	-3.1	-2.9	-2.8
Hypertension (Self-reported)	1.3	3.7	16.9	0.5	3.1	2.1	0.9	0.2	-4.1	0.7	0.5	0.5
Schizophrenia vs Biploar Disorder	1.2	1.5	3.0	1.4	-0.4	0.3	1.1	1.5	-1.4	1.7	1.1	1.4
Hearing difficulty/problems with background noise	1.2	1.8	4.4	-2.0	0.0	0.0	-0.7	-2.1	-0.0	-1.6	-1.0	-1.9
Financial difficulties in last 2 years	1.2	1.6	4.9	1.1	-1.7	-1.0	0.5	1.4	2.2	0.7	1.2	0.3
Medication: Lansoprazole	1.2	1.3	3.3	-1.2	1.8	0.8	-0.4	-1.3	-0.6	-1.1	-1.2	-1.3
Eye problems/disorders: Glaucoma	1.2	1.4	4.3	1.2	0.2	0.3	2.1	1.3	-0.5	2.0	0.8	0.7
Prostate Cancer	1.1	1.6	9.1	-0.1	1.2	3.0	-0.3	-0.5	-1.5	-0.6	-0.4	0.5
Primary Biliary Cirrhosis	1.1	1.6	3.5	1.3	0.3	0.2	1.5	1.4	-1.9	1.5	0.7	1.4
Lung FEV1/FVC ratio	1.1	5.4	11.0	3.0	0.9	-1.7	2.7	2.6	-1.3	3.3	1.9	2.4
Pack years adult smoking proportion	1.1	1.7	3.4	-1.7	-0.0	-0.4	-1.0	-1.5	-1.8	-1.1	-1.6	-1.3
Age when periods started (menarche)	1.1	2.7	4.7	1.9	-1.0	-0.9	1.4	2.0	1.2	1.8	2.2	2.0
Pain all over the body in last month	1.1	1.2	3.4	-1.3	-0.1	0.1	-0.4	-1.2	-1.3	-0.8	-1.4	-1.8
Loud music exposure frequency	1.1	1.3	4.1	0.9	-1.4	0.1	0.4	1.0	2.0	0.4	1.4	1.0
Forced expiratory volume in 1-second (FEV1), predicted	1.1	2.3	7.0	1.1	1.0	-1.0	1.1	1.9	2.7	1.9	1.6	0.3
Loneliness, isolation	1.1	1.6	3.2	1.3	0.4	0.3	1.3	1.3	1.8	1.0	1.5	1.5
Illnesses of father: High blood pressure	1.1	1.3	3.2	1.1	0.9	1.6	1.8	1.1	-0.6	1.3	0.1	1.1
Deep venous thrombosis (DVT) (self-reported)	1.1	1.5	3.4	1.5	0.2	0.7	1.4	1.2	-0.2	1.2	1.4	1.8
Heart disease (siblings)	1.1	1.4	3.2	0.9	1.8	1.7	1.3	0.5	-1.3	0.4	0.8	1.0
Ulcerative Colitis	1.0	1.4	3.0	-1.2	0.2	-0.6	-1.7	-1.4	-1.5	-0.9	-0.9	-1.6
Eye problems/disorders: Diabetes related eye disease	1.0	1.1	2.5	1.1	0.8	0.9	1.6	0.7	-1.1	1.2	-0.2	1.2
Diabetes (mother)	1.0	1.2	2.2	-1.4	1.3	-1.3	-1.0	-1.2	0.4	-0.9	-0.1	-1.5
Severe depression (siblings)	1.0	1.1	4.8	-0.7	0.7	2.2	-0.7	-0.6	-1.1	-1.2	-0.6	-0.5
Chronic bronchitis/emphysema (father)	1.0	1.2	3.0	-1.0	0.2	-0.7	-0.9	-1.5	-0.8	-1.3	-1.7	-0.9
Had menopause	1.0	1.3	4.4	-0.6	1.6	1.3	-1.0	-0.8	-2.1	-0.7	-0.3	-0.2
Number of live births	1.0	1.4	3.4	-1.3	0.9	-0.9	-1.1	-1.1	-1.8	-0.7	-0.8	-1.6
Glaucoma (self-reported)	1.0	1.2	3.0	1.2	0.5	0.3	1.4	1.4	0.0	1.7	1.1	1.0
Birth weight	1.0	2.2	6.2	-0.6	-2.5	-2.3	-1.2	-0.4	1.8	-0.7	-0.9	-1.2
Supplements: Vitamin C	1.0	1.2	3.3	0.8	-0.5	-0.7	0.8	1.1	1.7	1.0	1.8	0.8
Age started oral contraceptive pill	1.0	1.3	5.6	0.1	1.1	2.4	0.1	-0.1	-1.9	-0.1	-0.1	0.9
Mean Putamen Volume	0.9	1.0	2.2	-1.5	0.7	-1.1	-0.8	-1.1	-0.9	-0.8	-0.9	-1.1
Lupus	0.9	1.4	3.2	-0.9	-1.1	-0.9	-0.4	-1.2	-1.4	-1.1	-1.8	-1.3
Frequency of unenthusiasm / disinterest in last 2 weeks	0.9	1.1	3.5	0.8	1.4	-0.1	1.1	0.6	1.3	0.3	1.9	1.0
Ever unenthusiastic/disinterested for a whole week	0.9	1.1	2.8	1.2	0.4	-0.1	1.3	1.3	0.3	1.2	0.4	1.7
Time employed in main current job	0.9	1.0	2.6	1.2	-0.4	1.4	1.6	0.5	0.8	0.7	-0.0	1.3
Forced expiratory volume in 1-second (FEV1)	0.9	3.0	8.8	1.7	1.4	0.8	0.8	2.3	3.0	1.9	1.6	0.9
Mouth/teeth dental problems: Dentures	0.9	1.5	2.8	-1.4	0.4	-0.4	-0.7	-1.5	-1.6	-1.2	-1.7	-1.2
Medication: Amlodipine	0.9	1.2	8.0	0.2	2.8	-0.2	0.8	0.2	-0.6	0.3	1.3	0.1
Medication: Allopurinol	0.9	1.2	3.7	-1.1	0.5	0.8	-0.7	-1.2	-1.1	-1.0	-1.9	-0.9
Medication: Omeprazole	0.9	1.1	2.4	0.9	0.9	1.6	-0.2	1.3	-0.6	0.9	1.3	1.1
Leg pain on walking	0.9	1.2	2.2	-1.2	-0.5	0.2	-1.4	-1.2	-0.1	-1.5	-1.2	-1.3
Friendships satisfaction	0.9	1.2	2.3	1.0	0.0	-1.1	0.9	1.1	0.1	1.4	1.3	1.5
Qualifications: nursing, teaching	0.9	1.3	3.5	-1.5	-0.7	-0.4	-1.9	-1.1	0.9	-1.1	-0.5	-1.5
Medication: Paracetamol	0.9	1.4	3.3	-1.4	-1.2	0.6	-0.9	-1.1	0.0	-1.4	-1.8	-1.2
Average weekly beer plus cider intake	0.9	1.4	2.0	-1.4	-1.2	-1.2	-1.4	-0.8	1.4	-1.1	-0.7	-1.1
Myopia	0.9	1.3	4.8	0.8	1.2	-1.7	0.3	0.7	1.2	0.5	2.2	0.2
Cholesterol lowering medication	0.9	1.3	3.8	-0.7	1.9	1.9	-0.1	-0.6	-1.8	-0.5	-0.7	-0.1
Schizophrenia (2014)	0.8	1.7	3.3	1.4	1.5	1.8	0.5	1.3	-0.5	0.8	1.4	1.6
Number of treatments/medications taken	0.8	1.4	5.3	0.1	1.3	2.2	0.8	0.1	-2.3	0.4	-0.2	0.1
Tinnitus: Yes, but not now, but have in the past	0.8	0.8	3.0	0.3	0.4	1.2	0.6	0.5	1.7	0.0	1.4	0.1
Alcohol usually taken with meals	0.8	1.4	3.4	1.1	1.8	0.9	0.1	1.0	-0.1	0.9	1.8	1.4
Forced vital capacity (FVC)	0.8	3.0	13.3	1.3	1.2	1.4	0.1	2.0	3.6	1.2	1.5	0.6
Weight	0.8	3.9	7.7	-2.5	-0.4	0.2	-2.8	-2.3	0.8	-2.6	-1.9	-2.1
Frequency of tiredness / lethargy in last 2 weeks	0.8	1.4	2.8	-1.6	-0.1	0.3	-0.2	-1.4	-0.6	-1.6	-1.3	-1.7
Number of full brothers	0.8	1.0	2.2	0.8	1.1	-1.0	0.7	1.1	1.5	0.9	1.1	0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.8	0.9	3.2	0.4	1.6	-0.9	0.1	0.7	1.8	0.2	0.9	0.2
Medication: Aspirin	0.8	1.0	2.7	0.4	1.7	1.6	1.5	0.3	-0.6	0.6	0.8	0.3
Long-standing illness, disability or infirmity	0.8	1.3	6.2	-0.1	1.7	2.5	-0.1	-0.0	-1.4	0.2	-0.5	-0.3
Arm fat mass (left)	0.8	3.4	7.3	-2.3	-0.2	-0.0	-2.5	-2.5	0.3	-2.7	-1.5	-1.8
Pain type(s) experienced in last month: Hip pain	0.8	1.0	3.4	-0.7	0.7	1.7	0.3	-0.6	-1.8	0.1	-1.1	-0.1
High cholesterol (Self-reported)	0.8	1.5	7.4	-0.0	1.2	2.1	-0.2	-0.2	-2.7	-0.1	-0.4	0.2
Verbal and Numeric Reasoning (VNR)	0.7	1.6	4.7	1.3	0.1	2.2	1.9	0.9	-0.8	0.7	0.9	1.3
Type 2 Diabetes (T2D) (2012)	0.7	0.8	2.2	0.5	-1.0	-1.5	-0.3	0.9	1.1	0.7	0.8	0.5
Other serious medical condition/disability diagnosed by doctor	0.7	0.9	6.5	0.2	-0.3	2.5	0.3	0.3	-1.0	-0.1	-0.7	0.4
Waist circumference	0.7	2.6	5.1	-2.0	-0.6	1.2	-1.4	-1.8	1.9	-2.3	-1.4	-1.4
Medication: Simvastatin	0.7	1.1	4.1	-0.1	1.7	1.3	1.0	-0.4	-2.0	0.2	-0.1	-0.1
Arm fat mass (right)	0.7	3.0	6.2	-2.1	-0.0	-0.0	-2.4	-2.3	0.6	-2.5	-1.3	-1.7
Comparative body size at age 10	0.7	1.9	9.9	-1.3	-0.5	-3.1	-0.8	-1.1	-1.1	-0.4	-0.5	-1.3
Alcohol intake frequency.	0.7	1.6	3.8	-1.7	0.9	0.1	-1.2	-1.9	-0.4	-1.4	-1.4	-1.1
Overall health rating	0.7	1.4	7.5	0.2	1.4	2.7	1.4	0.5	-0.8	0.2	-0.2	0.5
Illness, injury, bereavement, stress in last 2 years	0.7	0.8	5.1	-0.5	0.2	0.8	0.3	-0.8	-2.3	-0.2	-0.8	-0.3
Diabetes diagnosed by doctor	0.7	1.2	3.3	0.8	1.1	1.8	1.2	0.5	-0.8	1.0	0.5	1.3
Mouth/teeth dental problems: Mouth ulcers	0.7	1.2	3.9	1.1	-0.8	0.8	0.6	1.1	1.2	0.6	2.0	0.8
Average weekly champagne plus white wine intake	0.7	0.9	5.3	0.3	0.5	0.3	-0.4	0.6	2.3	0.1	1.3	-0.1
Commuting to job workplace: Public transport	0.7	0.8	2.4	0.4	-0.0	1.5	1.0	0.8	0.3	1.0	1.2	0.9
Major Depression (MDD)	0.6	0.7	1.4	1.1	-0.6	1.0	0.7	0.6	-1.0	0.8	-0.0	1.2
Triglycerides	0.6	1.0	2.7	-1.2	0.4	1.2	-1.1	-1.4	-0.1	-1.6	-0.6	-0.3
Height	0.6	10.9	34.6	2.8	-2.1	2.6	2.9	4.2	5.9	3.6	1.4	1.8
Sensitivity / hurt feelings	0.6	1.0	6.0	0.0	2.4	0.2	0.7	-0.2	-1.2	0.1	1.0	-0.1
Frequency of depressed mood in last 2 weeks	0.6	0.8	2.6	0.4	0.9	0.6	1.6	0.7	0.8	0.7	1.2	0.4
Medication: Metformin	0.6	0.8	2.4	0.8	-0.4	1.5	1.2	0.6	-0.4	0.8	0.4	1.3
Maternal smoking around birth	0.6	0.8	3.1	-0.7	0.1	-1.7	-0.5	-0.7	-1.3	-0.5	-0.6	-0.8
Bilateral oophorectomy (both ovaries removed)	0.6	0.7	1.3	-1.1	-0.3	0.6	-0.1	-0.7	-0.3	-1.1	-1.1	-1.1
Stomach or abdominal pain in last month	0.6	0.7	3.0	0.2	1.7	0.9	0.6	0.1	-1.3	0.4	0.7	0.4
Qualifications: None of the above	0.6	1.2	3.4	-0.7	-0.8	-1.3	-0.6	-0.6	-1.5	-0.1	-1.8	-1.3
Diabetes (self-reported)	0.6	0.9	2.2	0.9	0.5	1.5	1.0	0.6	-0.8	1.0	0.2	1.4
Serious illness, injury or assault of a close relative in last 2 years	0.6	0.6	1.7	0.8	0.2	-0.3	0.6	1.1	1.3	0.8	1.0	0.3
Illnesses of mother	0.6	0.8	2.1	-0.8	-1.4	-1.1	-1.3	-0.8	0.3	-0.4	-0.4	-0.6
Forced expiratory volume in 1-second (FEV1), Best measure	0.6	1.9	4.6	1.3	1.1	0.7	1.0	1.8	2.1	1.7	1.1	0.7
Standing height	0.6	5.8	21.2	1.8	-1.8	1.0	2.0	3.0	4.6	2.7	1.4	1.0
Breastfed as a baby	0.6	0.8	5.0	0.6	0.3	0.5	0.8	0.3	-2.2	0.5	-0.5	0.3
Headache pain in last month	0.6	1.1	3.4	-0.8	-0.1	1.8	-0.2	-1.0	-0.8	-1.3	-1.4	-0.7
Medication: Ventolin 100micrograms inhaler	0.6	0.7	2.9	-0.6	1.2	1.7	-0.0	-0.3	-0.7	-0.3	-0.9	-0.5
Seen a psychiatrist for nerves, anxiety, tension or depression	0.6	0.8	1.6	-1.0	0.1	1.2	-0.7	-0.8	-1.1	-0.9	-1.3	-0.2
Reason for reducing amount of alcohol drunk: Health precaution	0.6	0.7	2.1	0.6	-0.4	0.7	1.5	0.7	0.5	1.2	1.2	0.2
Eye problems/disorders: None of the above	0.6	0.7	2.0	-0.7	-0.5	-0.4	-1.3	-0.9	-0.4	-1.4	-0.6	-0.3
Family relationship satisfaction	0.6	0.7	2.8	0.7	-0.8	-1.7	0.6	0.7	-0.2	1.1	0.3	0.6
Medication for cholesterol	0.6	0.9	5.9	0.3	-1.2	-0.4	-0.1	0.4	2.4	0.2	0.4	0.1
Medication: Aspirin	0.6	0.8	2.3	0.2	1.5	1.5	1.3	-0.0	-1.0	0.4	0.5	0.1
Supplements: Calcium	0.6	0.7	1.8	1.0	0.2	0.6	1.3	0.8	0.8	0.8	0.4	0.8
Neuroticism (Nagel 2018)	0.5	1.2	5.3	0.3	2.3	1.5	1.1	0.2	-0.5	-0.1	1.3	0.7
Worry (Nagel 2018)	0.5	1.1	4.7	-0.6	2.2	1.3	0.2	-0.2	-1.7	-0.4	0.5	-0.1
Reaction Time	0.5	0.9	4.1	-0.7	-0.9	-2.0	-1.0	-0.4	-0.3	-0.5	0.1	-1.2
LDL Cholesterol	0.5	0.7	2.6	-0.0	-0.2	1.6	-0.2	-0.7	-1.6	-0.6	-0.6	0.4
Rheumatoid Arthritis	0.5	0.6	1.3	-1.1	-0.3	-0.7	-1.1	-0.9	0.1	-0.8	-0.3	-1.1
Diabetes (father)	0.5	0.6	3.7	0.0	1.9	0.7	0.8	-0.3	0.1	0.0	0.4	0.4
Fed-up feelings	0.5	0.9	5.0	0.5	0.2	2.2	1.3	0.2	-0.1	-0.2	0.1	0.9
Heel bone mineral density (BMD) T-score, automated (left)	0.5	1.2	8.2	0.6	2.9	0.4	-0.1	0.2	0.9	0.5	1.1	0.4
Serious illness, injury or assault to yourself	0.5	0.6	1.2	0.7	-1.1	-0.3	0.6	1.1	1.0	0.8	-0.1	0.7
Nervous feelings	0.5	0.9	3.8	0.1	1.9	1.1	0.7	0.3	-1.5	0.3	0.4	0.4
Heel bone mineral density (BMD) T-score, automated (right)	0.5	1.2	6.2	0.6	2.5	0.0	0.4	0.3	1.5	0.8	1.2	0.2
Mouth/teeth dental problems	0.5	0.8	2.0	0.9	0.6	-0.5	0.6	1.0	1.4	1.3	0.2	0.6
Allergy	0.5	1.2	3.0	-0.9	0.3	-1.6	-0.8	-1.2	-1.7	-0.9	-0.9	-1.0
Hayfever/allergic rhinitis (self-reported)	0.5	0.6	1.0	-0.9	0.9	0.8	-1.0	-0.9	-0.3	-1.0	0.0	-0.7
Fluid intelligence score	0.5	1.0	4.0	0.5	-0.5	1.4	1.4	0.3	-2.0	0.5	-0.1	0.6
Neuroticism score	0.5	1.1	5.5	-0.1	2.3	1.6	0.6	-0.2	-0.1	-0.6	0.7	0.5
Worrier / anxious feelings	0.5	0.9	5.3	-0.5	2.3	0.3	-0.1	-0.3	-1.1	-0.6	0.7	-0.4
Asthma	0.5	1.0	1.8	-1.1	-1.1	1.0	-1.3	-0.6	1.1	-1.2	-0.7	-0.7
Qualifications: O levels/GCSEs or equivalent	0.5	0.8	3.6	0.4	0.5	0.5	0.7	0.4	1.5	-0.2	1.9	0.7
Mouth/teeth dental problems: Bleeding gums	0.5	0.6	2.9	0.4	0.0	1.7	0.4	-0.0	-1.0	-0.3	0.5	0.8
Gout (self-reported)	0.5	0.6	2.3	-0.4	0.8	0.9	-0.4	-0.4	-1.5	-0.5	-0.9	-0.4
Worry too long after embarrassment	0.5	0.8	2.7	0.3	1.7	1.5	1.0	0.2	-0.5	-0.1	0.5	0.4
Number of children fathered	0.5	0.6	1.6	-0.4	-1.3	-0.9	-0.8	-0.2	0.9	-0.4	-0.5	-0.9
Health satisfaction	0.5	0.6	2.1	-0.5	0.7	1.5	-0.2	-0.8	-0.5	-1.0	-0.6	-0.6
Mouth/teeth dental problems: Loose teeth	0.5	0.6	1.8	0.9	0.6	0.4	0.5	1.0	-0.4	0.7	1.3	0.8
Medication: Seretide 50 evohaler	0.5	0.6	2.2	-0.4	0.7	-0.7	-1.5	-0.7	0.3	-1.0	0.2	-0.6
Suffer from ‘nerves’	0.5	0.8	3.3	-0.8	0.8	1.8	0.2	-0.8	-1.1	-0.9	-0.4	-0.3
Had major operations	0.5	0.6	2.0	-0.3	-0.8	0.0	-0.5	-0.7	-1.4	-0.7	-1.1	-0.6
Mood swings	0.5	0.9	2.6	-1.2	0.5	1.0	-0.2	-1.3	0.5	-1.6	-1.0	-0.6
Medication: Gliclazide	0.5	0.6	1.3	-1.0	-0.9	0.2	0.3	-0.9	-1.0	-0.3	-1.2	-0.1
Miserableness	0.5	0.9	4.2	0.0	2.0	1.1	1.3	-0.3	0.2	-0.3	0.9	0.2
Irritability	0.5	0.8	2.9	0.4	0.3	1.1	0.5	0.3	1.7	-0.3	1.4	0.9
Ever depressed for a whole week	0.5	0.7	2.2	0.8	-0.3	0.4	1.1	0.8	0.4	0.8	0.4	1.5
Schizophrenia (2018)	0.4	0.8	2.8	0.5	1.4	1.0	-0.3	0.8	0.2	0.3	1.7	0.9
Alzheimer’s Disease (in father)	0.4	0.4	1.5	-0.6	0.1	0.3	-0.1	-0.6	0.9	-0.8	-0.2	-1.2
Alzheimer’s Disease (including proxy)	0.4	0.5	1.4	1.2	-0.1	0.2	1.0	0.9	-0.1	1.2	0.4	0.4
Ulcerative Colitis (UC)	0.4	0.7	1.6	-0.8	0.8	0.3	-0.6	-0.9	-1.0	-0.9	-0.6	-1.3
Breast Cancer	0.4	0.9	2.2	-1.1	-1.5	0.2	-1.1	-1.0	-0.1	-0.9	-1.2	-0.6
Fasting Glucose	0.4	0.4	1.1	-0.8	-0.1	-0.7	-0.1	-0.3	0.9	-0.7	-0.5	-1.1
HbA1C	0.4	0.5	1.3	0.0	1.1	0.8	-0.2	-0.6	0.9	-0.5	0.8	-0.2
Type 2 Diabetes (T2D) (2018)	0.4	0.7	2.5	0.5	1.2	1.6	0.6	0.2	0.2	0.7	0.3	0.9
Neuroticism	0.4	1.0	3.9	-0.2	1.7	2.0	0.2	-0.2	-1.1	-0.7	0.4	0.5
Hearing difficulty/problems: Yes	0.4	0.6	1.6	-0.9	0.0	-1.2	0.6	-0.7	0.1	0.2	-0.7	-1.3
Ever had hysterectomy (womb removed)	0.4	0.4	2.6	0.4	1.6	0.6	0.5	0.2	-0.4	0.1	-0.0	0.4
Medication for hormone replacement therapy	0.4	0.5	2.5	-0.4	0.4	0.1	0.6	-0.8	-1.6	-0.5	-0.4	-0.3
Supplements: Zinc	0.4	0.4	2.4	0.3	-0.2	1.6	0.2	0.5	-0.0	0.1	0.4	0.7
Sitting height	0.4	3.1	7.3	-2.1	1.1	0.9	-1.5	-1.6	2.7	-1.4	-1.3	-2.4
Number of incorrect matches in round	0.4	0.6	2.0	-0.7	-0.9	-0.5	0.4	-0.6	-1.4	0.2	-0.5	-1.0
Hip circumference	0.4	1.9	4.0	-1.7	0.3	0.2	-2.0	-1.7	-0.0	-1.8	-1.3	-1.5
Hair/balding pattern: Pattern 3	0.4	0.5	2.4	-0.1	-1.5	1.1	0.3	0.1	0.7	-0.1	0.6	0.5
Depression (self-reported)	0.4	0.5	1.1	-0.7	-1.0	-1.0	-0.1	-0.4	-0.9	-0.3	-0.3	-0.8
Lung cancer (father)	0.4	0.5	1.8	0.3	-1.3	0.1	0.3	0.2	-0.4	0.3	-1.3	-0.3
Seen doctor (GP) for nerves, anxiety, tension or depression	0.4	0.7	2.1	-0.4	-1.2	1.5	-0.3	-0.4	-0.2	-0.6	-1.3	-0.3
Forced vital capacity (FVC), Best measure	0.4	1.6	5.4	1.0	0.8	1.9	0.4	1.5	2.3	1.0	0.8	0.5
Leg fat percentage (right)	0.4	1.3	4.3	1.1	0.4	0.9	0.6	0.9	2.1	0.1	1.6	1.3
Migraine (self-reported)	0.4	0.6	1.3	-0.1	1.1	1.0	0.4	-0.3	-1.1	-0.2	-1.1	-0.2
Mean time to correctly identify matches	0.4	0.7	2.5	-0.6	-1.0	-1.6	-0.7	-0.5	-1.0	-0.5	-0.1	-1.0
Asthma (self-reported)	0.4	0.8	1.8	-1.1	-0.7	0.7	-1.3	-0.6	1.0	-1.2	-0.5	-0.7
Mother’s age at death	0.4	0.5	3.7	0.2	0.8	-0.1	0.2	0.3	1.9	0.1	0.7	-0.1
Medication: Blood pressure	0.4	0.8	3.4	-0.7	0.2	0.6	-0.8	-0.6	-1.9	-0.7	-1.1	-0.4
Commuting to job workplace: Cycle	0.4	0.5	1.9	-0.6	0.9	1.4	-0.4	-0.8	0.6	-0.6	-0.2	-0.1
Alcohol drinker status: Previous	0.4	0.5	2.2	0.5	-0.6	1.5	0.6	0.2	-0.8	0.1	-0.3	0.8
Depressed Affect (Nagel 2018)	0.3	0.7	1.7	0.2	1.3	1.3	0.8	0.1	0.8	-0.3	1.0	0.7
Allergy or Eczema	0.3	0.9	2.8	0.5	1.5	1.7	0.3	0.3	1.1	0.5	0.7	0.5
Respiratory disease	0.3	0.7	2.5	-0.7	-0.6	1.6	-1.2	-0.3	0.2	-0.9	0.1	-0.3
Lung FVC	0.3	1.7	6.0	-0.6	2.2	2.5	-1.1	-0.6	1.1	-0.8	0.3	-0.5
Tanning	0.3	3.2	7.8	-1.8	-0.4	-1.0	-2.8	-2.0	-0.7	-2.1	-1.8	-2.0
Trunk fat percentage	0.3	1.4	4.9	1.1	-0.1	1.1	0.8	1.0	2.2	0.4	1.4	1.1
Hayfever, allergic rhinitis or eczema	0.3	0.6	2.0	0.5	1.4	1.2	0.4	0.4	1.1	0.6	0.4	0.3
Multivitamins +/- minerals	0.3	0.4	1.1	-0.6	-0.6	-0.6	-0.2	-0.7	0.1	-0.5	-1.1	-0.7
Medication: Levothyroxine sodium	0.3	0.5	1.2	-0.6	0.7	0.5	-0.5	-0.9	-1.1	-0.5	-0.5	-0.6
High blood pressure (mother)	0.3	0.4	2.0	-0.0	1.4	1.0	0.5	0.2	0.7	-0.4	0.3	0.1
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.5	1.1	-1.0	1.0	-0.0	-0.2	-0.8	0.4	-0.8	0.0	-0.9
Medication: Ramipril	0.3	0.3	1.6	-0.2	1.3	0.8	0.3	0.1	-0.5	0.0	0.6	0.4
Arm fat percentage (right)	0.3	1.2	2.9	-1.3	-0.0	-0.3	-1.4	-1.5	0.7	-1.7	-0.4	-1.0
Father’s age at death	0.3	0.4	2.1	0.2	-0.8	-0.5	0.1	0.3	1.4	0.1	0.3	0.4
Length of working week for main job	0.3	0.4	2.2	-0.4	0.3	1.5	0.4	-0.6	-0.3	-0.4	-0.4	0.3
Exposure to tobacco smoke at home	0.3	0.3	0.9	0.7	0.2	0.5	0.9	0.2	-0.9	0.4	0.2	0.5
Hair/balding pattern: Pattern 4	0.3	0.7	2.8	0.5	1.7	-0.7	0.6	0.2	-0.6	0.7	1.1	0.4
Medication: Paracetamol	0.3	0.5	1.6	-0.7	-0.9	0.3	-0.3	-0.5	0.3	-0.9	-1.3	-0.6
Body fat percentage	0.3	1.2	4.3	1.0	0.0	1.0	0.6	0.8	2.1	0.2	1.4	1.1
Exposure to tobacco smoke outside home	0.3	0.4	1.2	-0.7	0.8	0.0	-0.4	-1.1	0.0	-0.8	-0.6	-0.5
Qualifications: College or University degree	0.3	0.9	4.7	-0.3	-0.6	1.2	-0.2	-0.5	-2.2	-0.5	-1.0	-0.2
Emphysema/chronic bronchitis	0.3	0.3	1.4	-0.0	0.6	1.2	0.2	-0.2	-0.9	0.0	0.2	-0.2
Pulse rate, automated reading	0.3	1.1	3.4	1.1	0.5	-0.4	0.7	1.3	-1.8	1.2	-0.1	1.0
Comparative height size at age 10	0.3	1.6	3.2	0.5	-1.7	0.1	1.6	1.5	1.5	1.8	-0.7	-0.1
Arm fat percentage (left)	0.3	1.3	3.5	-1.4	-0.1	-0.1	-1.5	-1.7	0.3	-1.9	-0.6	-1.0
Ever had bowel cancer screening	0.3	0.4	1.0	-0.6	0.0	0.1	-0.4	-0.6	-0.5	-0.6	-1.0	-0.8
Eye problems/disorders: Cataract	0.3	0.3	0.8	0.4	0.1	0.5	0.9	0.6	0.7	0.8	0.2	0.0
Mineral and other dietary supplements	0.3	0.4	1.6	-0.4	1.3	-0.6	0.2	-0.5	-1.0	-0.1	0.0	-0.7
Osteoporosis (self-reported)	0.3	0.4	3.1	-0.0	-0.2	-0.3	0.2	0.0	1.7	-0.2	0.4	-0.1
Medication: Bendroflumethiazide	0.3	0.5	1.7	-0.0	-1.3	0.4	0.7	-0.0	-1.1	-0.0	-1.0	0.0
Ever smoked	0.3	0.4	1.2	0.4	0.2	0.9	-0.5	0.3	1.1	-0.3	1.0	0.6
Ever had prostate specific antigen (PSA) test	0.3	0.3	1.4	0.2	1.2	0.6	0.7	0.3	-0.3	0.5	0.1	0.0
Leg fat mass (left)	0.3	1.0	2.6	-0.8	0.2	0.8	-1.4	-1.0	1.4	-1.6	-0.2	-0.5
Bipolar Disorder or Schizophrenia	0.2	0.6	1.8	0.4	0.7	1.3	-0.3	0.8	0.3	0.0	1.1	0.7
Intelligence (Savage-Jansen 2018)	0.2	0.7	2.6	0.9	0.6	1.6	1.4	0.2	-0.6	0.1	0.1	0.7
Neuroticism (2016)	0.2	0.3	2.6	0.0	-0.4	-0.1	-0.4	-0.2	-1.6	-0.3	0.0	0.3
Blood Eosinophil Count	0.2	1.2	2.6	-0.9	1.0	1.6	-1.4	-0.8	1.6	-1.2	0.3	0.1
Hypothyroidism (self reported)	0.2	0.4	1.9	0.4	0.7	1.4	0.1	0.2	-0.7	0.1	0.7	0.6
Relative age of first facial hair	0.2	0.4	0.9	-0.2	-0.8	1.0	-0.7	-0.3	1.0	-0.6	-0.3	0.3
Vitamin and mineral supplements	0.2	0.2	1.0	-0.1	0.5	0.4	-0.7	-0.2	-1.0	-0.2	-0.3	0.1
Medication: Co-codamol	0.2	0.3	1.0	-0.9	0.2	-0.4	-0.1	-0.7	-0.0	-0.2	-0.1	-1.0
Relative age voice broke	0.2	0.4	1.8	-0.1	-0.7	0.2	-0.4	-0.3	1.3	-0.7	-0.2	-0.3
Qualifications: CSEs or equivalent	0.2	0.2	0.9	0.1	0.9	0.1	-0.3	0.2	1.0	0.1	0.3	-0.1
Past tobacco smoking	0.2	0.3	1.4	0.4	-0.4	-0.3	0.8	0.3	-1.2	0.7	-0.1	0.3
Pulse rate	0.2	0.3	2.1	0.1	-0.2	-0.1	0.2	0.2	-1.5	0.2	-0.6	-0.3
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.2	0.5	0.3	0.2	-0.1	0.7	0.5	0.7	0.3	-0.1	0.7
Peak expiratory flow (PEF)	0.2	0.6	2.3	0.7	0.4	-0.2	-0.5	1.0	1.5	0.7	0.7	0.4
Hypothyroidism/myxoedema (self-reported)	0.2	0.4	1.1	-0.5	1.0	0.6	-0.5	-0.8	-0.9	-0.6	-0.3	-0.3
Leg fat mass (right)	0.2	0.9	2.9	-0.7	0.3	0.4	-1.2	-0.8	1.7	-1.4	0.1	-0.4
Number of full sisters	0.2	0.2	0.8	-0.3	0.9	-0.4	-0.6	-0.1	0.6	-0.2	0.5	-0.1
Illnesses of siblings: Diabetes	0.2	0.2	0.7	-0.4	-0.7	0.0	-0.8	-0.3	0.3	-0.4	-0.6	-0.4
Smoking status: Previous	0.2	0.3	1.1	-0.2	0.6	0.2	-0.9	0.1	1.1	-0.5	-0.1	-0.3
Smoking status: Current	0.2	0.3	0.8	-0.4	-0.3	0.8	-0.2	-0.9	-0.5	-0.7	-0.3	-0.4
Ever taken oral contraceptive pill	0.2	0.2	0.4	-0.5	0.5	-0.6	0.6	-0.4	-0.0	-0.1	-0.5	-0.4
Hearing aid user	0.2	0.2	1.0	-0.5	0.2	-1.0	-0.3	0.0	-0.2	-0.1	0.6	-0.6
Alcohol drinker status: Never	0.2	0.2	1.0	-0.3	0.3	0.2	-0.4	-0.2	1.0	-0.0	0.6	-0.1
Leg fat percentage (left)	0.2	0.8	2.0	0.7	0.4	1.4	0.2	0.5	1.4	-0.2	1.2	1.0
Fractured/broken bones in last 5 years	0.2	0.3	1.2	0.3	-0.8	-1.1	0.2	0.4	-0.0	0.4	-0.3	0.2
Bipolar Disorder (2018)	0.1	0.2	0.8	0.1	-0.5	0.9	-0.1	0.2	0.3	-0.3	-0.2	0.1
Irritable Bowel Disease (IBD)	0.1	0.2	0.5	0.2	0.2	-0.7	0.3	0.4	0.7	0.1	0.6	-0.5
Blood Red Count	0.1	0.7	2.5	0.3	1.4	1.6	0.7	-0.0	-0.6	0.1	-0.6	0.6
Heel T-Score	0.1	0.6	1.7	-0.4	1.3	-0.4	-0.9	-0.8	0.4	-0.5	1.3	-0.5
Smoking Status	0.1	0.1	0.3	-0.4	-0.2	0.4	-0.4	-0.3	0.1	-0.4	-0.1	-0.5
Hand grip strength (left)	0.1	0.4	2.0	0.0	-0.2	-0.4	-1.4	-0.1	1.1	-0.1	0.2	0.2
Average weekly spirits intake	0.1	0.2	0.5	-0.1	-0.0	-0.0	-0.0	-0.4	-0.3	-0.5	-0.7	-0.7
Hand grip strength (right)	0.1	0.2	0.6	0.1	-0.8	0.4	-0.6	-0.2	0.4	-0.2	-0.4	0.3
Current tobacco smoking	0.1	0.2	0.5	-0.1	-0.3	0.7	-0.2	-0.5	-0.7	-0.4	-0.2	-0.3
Trunk fat mass	0.1	0.5	3.4	-0.2	-0.3	0.8	-0.5	-0.1	1.8	-0.6	0.2	-0.1
Hair/balding pattern: Pattern 2	0.1	0.1	0.6	0.3	-0.2	-0.8	0.2	0.1	-0.1	0.3	0.4	-0.0
Qualifications: A levels/AS levels or equivalent	0.1	0.3	1.2	0.2	-0.2	-1.1	0.5	0.3	0.5	0.3	1.1	0.2
Ever highly irritable/argumentative for 2 days	0.1	0.1	0.2	0.3	-0.4	0.2	0.0	0.4	0.2	-0.2	0.4	-0.0
Medication for pain relief, constipation, heartburn	0.1	0.1	0.8	-0.0	-0.3	-0.9	-0.2	-0.2	-0.0	0.3	-0.3	-0.2
Medication: Ibuprofen	0.1	0.2	0.5	-0.4	0.2	-0.4	0.1	-0.2	0.6	-0.2	-0.7	-0.2
Whole body fat mass	0.1	0.5	2.6	-0.4	-0.2	0.7	-0.8	-0.4	1.6	-0.9	0.1	-0.1
Chest pain or discomfort	0.1	0.2	0.9	0.1	0.2	0.2	-0.1	0.3	-0.4	0.2	1.0	-0.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.2	1.3	0.0	1.1	0.7	-0.4	0.2	0.0	0.3	0.1	-0.0
Guilty feelings	0.1	0.1	0.3	0.0	-0.5	-0.5	0.3	-0.2	0.4	-0.1	-0.0	0.1
Tinnitus: Yes, now most or all of the time	0.1	0.1	0.5	0.1	-0.3	0.7	0.5	-0.2	-0.3	-0.2	-0.1	0.3
Hair Pigment	0.0	0.2	0.8	0.2	-0.3	0.1	-0.4	0.3	-0.9	0.5	-0.1	0.7
Unable to work because of sickness or disability	0.0	0.0	0.2	-0.1	-0.2	0.0	0.2	-0.2	0.1	-0.0	0.0	-0.5

Hub : Genes

PDE5A

Models

Trait associations