Best TWAS P=2.41e-23 · Best GWAS P=4.41e-94 conditioned to 9.68e-49
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | FTO | 0.11 | 0.00 | bslmm | 739 | 0.02 | 1.6e-03 | -1.1 | 9.0 | 2.7e-19 | 0.38 | 0.09 | 0.55 | TRUE |
| 2 | GTEx | Testis | AKTIP | 0.19 | 0.00 | enet | 26 | 0.00 | 1.9e-01 | -2.1 | 9.9 | 2.4e-23 | 0.51 | 0.03 | 0.40 | TRUE |
| 3 | The Cancer Genome Atlas | Glioblastoma Multiforme | FTO | 0.27 | 0.16 | enet | 13 | 0.14 | 6.7e-05 | -1.8 | 8.4 | 2.9e-17 | 0.33 | 0.11 | 0.32 | TRUE |