[Hub]/) : Traits : Leg fat percentage (left) : ← →

chr2:99,468,341-101,731,705

Best TWAS P=1.46e-11 · Best GWAS P=4.3e-12 conditioned to 0.439

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
2	GTEx	Artery Aorta	AFF3	0.14	0.06	lasso	5	0.07	1.2e-04	-6.9	-6.8	1.5e-11	0.84	0.01	0.99	TRUE
5	GTEx	Skin Sun Exposed Lower leg	LONRF2	0.05	0.03	lasso	2	0.02	9.3e-03	5.7	-6.0	1.6e-09	0.56	0.32	0.10	TRUE
7	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	LONRF2	0.06	0.04	blup	69	0.04	3.4e-05	5.3	-6.0	1.4e-09	0.68	0.30	0.69	FALSE
6	GTEx	Thyroid	CHST10	0.05	0.05	lasso	5	0.03	2.6e-03	-5.5	-6.0	1.7e-09	0.60	0.38	0.41	FALSE
4	GTEx	Muscle Skeletal	LONRF2	0.07	0.08	lasso	4	0.08	2.5e-08	-5.6	-5.6	2.1e-08	0.54	0.95	0.05	FALSE
8	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	LONRF2	0.05	0.08	lasso	2	0.08	2.9e-05	5.6	-5.5	4.2e-08	0.66	0.16	0.35	FALSE
1	GTEx	Adrenal Gland	CHST10	0.18	0.04	lasso	4	0.05	5.6e-03	-5.5	5.5	4.3e-08	-0.70	0.30	0.22	FALSE
3	GTEx	Cells EBV-transformed lymphocytes	CHST10	0.25	0.15	lasso	4	0.12	9.1e-05	5.7	-5.3	1.4e-07	0.63	0.33	0.16	FALSE