Best TWAS P=1.92e-07 · Best GWAS P=7.65e-07 conditioned to 0.0144
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Breast Mammary Tissue | AP1S1 | 0.18 | 0.14 | lasso | 4 | 0.12 | 1.5e-06 | 4.4 | 5.2 | 1.9e-07 | -0.56 | 0.03 | 0.92 | TRUE |
2 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | C7orf52 | 0.23 | 0.10 | blup | 54 | 0.12 | 7.0e-06 | 4.4 | -5.1 | 2.9e-07 | 0.58 | 0.07 | 0.80 | FALSE |