[Hub]/) : Traits : Leg fat percentage (left) : ← →

chr7:98,244,565-99,827,148

Best TWAS P=3.16e-11 · Best GWAS P=1.58e-11 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex CPSF4 0.06 0.06 blup 313 0.07 6.6e-09 -6.7 -5.6 2.3e-08 0.88 0.01 0.99 FALSE
2 CommonMind Brain Pre-frontal Cortex LOC100289187 0.08 0.02 enet 14 0.03 4.5e-05 -5.7 5.4 7.1e-08 -0.83 0.21 0.79 FALSE
3 GTEx Adipose Visceral Omentum GS1-259H13.2 0.23 0.12 lasso 1 0.09 1.8e-05 -5.6 5.6 2.8e-08 -0.79 0.78 0.13 FALSE
4 GTEx Cells Transformed fibroblasts CPSF4 0.08 0.03 lasso 4 0.03 1.8e-03 -5.7 -5.7 9.0e-09 0.80 0.22 0.47 FALSE
5 GTEx Esophagus Mucosa GS1-259H13.2 0.07 0.07 lasso 3 0.05 1.7e-04 -5.6 5.8 7.0e-09 -0.82 0.24 0.65 FALSE
6 GTEx Lung ZKSCAN5 0.09 0.05 lasso 2 0.03 2.7e-03 -5.7 5.6 2.1e-08 -0.77 0.32 0.27 FALSE
7 GTEx Lung GS1-259H13.2 0.09 0.07 lasso 4 0.05 8.4e-05 -5.6 5.7 1.3e-08 -0.78 0.64 0.23 FALSE
8 GTEx Nerve Tibial GS1-259H13.2 0.15 0.10 lasso 4 0.09 3.4e-07 -5.6 5.6 2.8e-08 -0.78 0.89 0.11 FALSE
9 GTEx Thyroid GS1-259H13.2 0.26 0.05 enet 30 0.08 7.6e-07 -5.7 5.9 3.3e-09 -0.69 0.75 0.20 FALSE
10 METSIM Adipose ARPC1A 0.02 0.02 blup 308 0.02 1.6e-03 -4.7 -5.8 7.0e-09 0.80 0.06 0.89 FALSE
11 METSIM Adipose GS1-259H13.2 0.04 0.03 lasso 3 0.02 1.4e-03 -5.7 5.7 1.1e-08 -0.78 0.20 0.77 FALSE
12 ROSMAP Brain Pre-frontal Cortex GS1-259H13.2 0.07 0.05 bslmm 305 0.06 6.9e-08 -6.2 5.9 3.4e-09 -0.82 0.21 0.79 FALSE
13 The Cancer Genome Atlas Brain Lower Grade Glioma ZKSCAN5 0.03 0.04 lasso 2 0.03 1.0e-04 -6.6 -6.6 3.2e-11 0.96 0.01 0.99 TRUE
14 The Cancer Genome Atlas Prostate Adenocarcinoma ZKSCAN5 0.03 0.03 enet 8 0.03 5.4e-04 -6.7 -5.8 7.3e-09 0.80 0.01 0.85 FALSE