[Hub]/) : Traits : Leg fat percentage (left) : ← →

chr1:45,100,098-47,339,113

Best TWAS P=7.27e-09 · Best GWAS P=2.73e-08 conditioned to 0.0298

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	MUTYH	0.04	0.00	enet	23	0.00	8.5e-01	-2.7	5.3	1.1e-07	-0.61	0.08	0.56	FALSE
2	GTEx	Adipose Subcutaneous	RP11-767N6.2	0.03	0.03	enet	6	0.04	3.0e-04	-4.1	-5.7	1.0e-08	0.77	0.11	0.70	FALSE
3	GTEx	Adipose Visceral Omentum	PIK3R3	0.07	0.02	lasso	3	0.04	4.6e-03	-5.1	-5.2	1.7e-07	0.91	0.13	0.76	FALSE
4	GTEx	Breast Mammary Tissue	GPBP1L1	0.06	0.02	lasso	5	0.00	2.4e-01	-5.2	5.4	6.8e-08	-0.94	0.08	0.72	FALSE
5	GTEx	Colon Transverse	GPBP1L1	0.06	0.01	lasso	6	0.01	8.3e-02	-5.2	5.2	1.8e-07	-0.89	0.09	0.76	FALSE
6	GTEx	Esophagus Mucosa	GPBP1L1	0.04	0.02	lasso	3	0.02	1.5e-02	-5.2	5.2	2.0e-07	-0.96	0.09	0.64	FALSE
7	GTEx	Esophagus Muscularis	CCDC17	0.04	0.04	lasso	6	0.01	9.1e-02	-5.1	5.2	2.4e-07	-0.97	0.06	0.88	FALSE
8	GTEx	Muscle Skeletal	GPBP1L1	0.03	0.02	enet	19	0.03	7.2e-04	-5.4	5.2	2.0e-07	-0.85	0.05	0.91	FALSE
9	GTEx	Stomach	RP11-767N6.7	0.08	0.03	enet	16	0.05	1.3e-03	3.5	5.8	7.3e-09	-0.69	0.26	0.36	TRUE
10	GTEx	Testis	PIK3R3	0.08	0.05	enet	7	0.06	1.5e-03	-5.1	5.3	1.0e-07	-0.99	0.08	0.86	FALSE
11	GTEx	Testis	IPP	0.05	0.06	enet	8	0.03	1.4e-02	-5.2	-5.5	4.3e-08	0.95	0.07	0.79	FALSE
12	GTEx	Thyroid	MAST2	0.06	0.05	lasso	4	0.04	4.9e-04	-5.2	5.2	1.9e-07	-0.87	0.15	0.82	FALSE
13	GTEx	Thyroid	GPBP1L1	0.05	0.06	enet	6	0.07	7.9e-06	-4.7	5.2	2.5e-07	-0.86	0.16	0.83	FALSE
14	GTEx	Whole Blood	MAST2	0.03	0.02	lasso	3	0.02	2.9e-03	-5.5	5.5	3.7e-08	-0.93	0.06	0.88	FALSE
15	ROSMAP	Brain Pre-frontal Cortex	IPP	0.08	0.15	lasso	9	0.14	5.0e-18	-5.5	5.4	5.6e-08	-0.97	0.07	0.93	FALSE
16	ROSMAP	Brain Pre-frontal Cortex	RPS15AP10	0.03	0.05	blup	283	0.04	8.0e-06	-5.4	-5.5	3.7e-08	0.96	0.05	0.94	FALSE
17	YFS	Blood	CCDC17	0.04	0.02	lasso	8	0.02	6.8e-08	-5.2	5.4	8.2e-08	-0.95	0.09	0.91	FALSE
18	YFS	Blood	IPP	0.10	0.11	lasso	15	0.12	4.6e-36	-5.6	5.7	1.6e-08	-0.98	0.04	0.96	FALSE
19	The Cancer Genome Atlas	Breast Invasive Carcinoma	GPBP1L1	0.01	0.02	lasso	2	0.02	1.2e-04	-5.2	5.2	2.4e-07	-0.98	0.04	0.91	FALSE
20	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	GPBP1L1	0.05	0.05	blup	51	0.06	1.0e-03	-5.5	5.3	1.4e-07	-0.98	0.04	0.78	FALSE
21	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	GPBP1L1	0.07	0.10	lasso	3	0.09	6.3e-06	-5.2	5.2	2.3e-07	-0.98	0.04	0.96	FALSE
22	The Cancer Genome Atlas	Prostate Adenocarcinoma	GPBP1L1	0.04	0.04	blup	50	0.04	2.9e-05	-5.2	5.4	7.2e-08	-0.98	0.05	0.94	FALSE
23	The Cancer Genome Atlas	Stomach Adenocarcinoma	IPP	0.04	0.04	blup	47	0.04	1.4e-03	-5.2	5.5	4.5e-08	-0.98	0.03	0.80	FALSE
24	The Cancer Genome Atlas	Thyroid Carcinoma	GPBP1L1	0.11	0.06	lasso	3	0.06	1.6e-06	-5.2	5.1	2.9e-07	-0.96	0.08	0.92	FALSE