TWAS hub - RPS15AP10

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	ROSMAP	Brain Pre-frontal Cortex	0.0302	0.0153	3.3e-05	0.045	0.039	0.036	0.039	0.038	1.6e-06	8e-06	1.7e-05	8.8e-06	9.6e-06
2	TCGA	Ovarian Serous Cystadenocarcinoma	0.0440	0.0340	1.3e-03	0.017	0.012	0.021	NA	0.004	2.3e-02	5e-02	1.4e-02	NA	1.5e-01

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Blood Platelet Count	13.3	154.3	187.7	-13.7	-11.0
Blood Red Count	13.0	125.7	182.2	13.5	8.3
Hearing difficulty/problems: Yes	10.8	16.5	22.0	4.7	3.3
Osteoarthritis (self-reported)	8.7	11.2	11.3	-3.4	-3.3
Breast Cancer	7.8	18.8	22.7	4.8	3.9
Leg fat percentage (right)	7.7	28.0	32.0	-5.7	-4.9
Ever smoked	7.7	13.5	14.8	-3.8	-3.5
Leg fat percentage (left)	7.2	26.2	30.3	-5.5	-4.7
Had major operations	6.7	7.9	11.2	-3.4	-2.1
Exposure to tobacco smoke outside home	6.6	8.8	12.6	-3.6	-2.2
Hearing difficulty/problems with background noise	6.3	10.1	11.4	3.4	3.0
Worry too long after embarrassment	6.2	10.4	10.6	3.3	3.2
Sitting height	5.9	42.1	55.8	7.5	5.3
Number of operations (self-reported)	5.6	8.3	10.4	-3.2	-2.5
Smoking Status	5.5	13.1	15.8	-4.0	-3.2
Maternal smoking around birth	5.5	7.9	8.8	-3.0	-2.6
Length of working week for main job	5.4	6.0	6.8	-2.3	-2.6
Supplements: Glucosamine	5.3	7.0	10.2	-3.2	-1.9
Past tobacco smoking	5.2	9.5	9.7	3.0	3.1
Mouth/teeth dental problems	5.1	7.8	11.1	3.3	2.1
Diabetes (mother)	5.0	6.4	7.2	-2.4	-2.7
Age at First Birth	4.9	7.1	7.5	2.6	2.7
Mouth/teeth dental problems: Bleeding gums	4.7	6.1	9.7	-3.1	-1.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	4.7	5.6	7.3	-2.0	-2.7
Type 2 Diabetes (T2D) (2012)	4.6	5.3	6.8	-2.6	-2.0
Myopia	4.5	6.5	7.3	-2.7	-2.4
Neuroticism (2016)	4.4	6.3	6.8	2.4	2.6
Mouth/teeth dental problems: Dentures	4.4	7.4	8.4	-2.9	-2.5
Hypothyroidism/myxoedema (self-reported)	4.4	8.6	11.3	-3.4	-2.4
Rheumatoid Arthritis	4.3	6.0	6.7	-2.6	-2.3
Taking other prescription medications	4.3	6.6	7.8	-2.8	-2.3
Qualifications: College or University degree	4.3	13.5	18.2	4.3	3.0
Guilty feelings	4.3	6.4	7.6	2.3	2.8
Diabetes (father)	4.2	5.2	6.1	-2.5	-2.1
Ulcerative Colitis	4.1	5.9	6.9	2.6	2.2
Age started oral contraceptive pill	4.1	5.1	8.1	2.8	1.5
Severe depression (siblings)	4.0	4.5	4.7	2.1	2.2
Body fat percentage	3.9	15.3	17.3	-4.2	-3.6
Tinnitus: Yes, but not now, but have in the past	3.8	4.1	4.2	-2.0	-2.0
Hair/balding pattern: Pattern 3	3.8	5.6	6.2	-2.2	-2.5
HbA1C	3.7	4.2	5.9	-1.6	-2.4
BMI	3.7	21.5	28.1	-5.3	-3.9
Had menopause	3.7	4.6	7.1	2.7	1.4
Wheeze or whistling in the chest in last year	3.7	6.6	7.3	-2.7	-2.4
Lung FEV1/FVC ratio	3.6	18.3	31.2	-5.6	-2.3
Ever had hysterectomy (womb removed)	3.6	4.1	4.9	-2.2	-1.8
Body mass index (BMI)	3.5	14.9	19.5	-4.4	-3.2
Leg fat mass (right)	3.5	13.4	16.3	-4.0	-3.2
Comparative height size at age 10	3.5	19.2	24.0	4.9	3.8
Eye problems/disorders: Cataract	3.5	4.1	6.2	2.5	1.4
Fasting Glucose	3.4	4.0	6.0	-2.4	-1.4
Height	3.4	65.6	77.4	8.8	7.3
Hypothyroidism (self reported)	3.4	7.9	11.2	-3.3	-2.1
Neuroticism	3.4	8.1	8.9	3.0	2.7
Medication: Levothyroxine sodium	3.3	5.7	6.5	-2.5	-2.2
Arm fat percentage (right)	3.3	12.9	15.5	-3.9	-3.2
Eye problems/disorders: Glaucoma	3.3	3.9	4.3	-1.9	-2.1
Smoking status: Current	3.2	5.0	8.3	-2.9	-1.3
Average weekly spirits intake	3.1	3.8	4.3	-1.8	-2.1
Friendships satisfaction	3.1	3.8	4.4	2.1	1.8
Heart disease (siblings)	3.1	3.8	4.8	2.2	1.7
Leg fat mass (left)	3.1	12.1	14.8	-3.8	-3.1
Body Mass Index (BMI) (2010)	3.0	4.1	5.2	-2.3	-1.8
Standing height	3.0	29.9	36.7	6.1	4.8
Leg pain on walking	3.0	3.8	5.5	-2.4	-1.4
Pulse rate, automated reading	2.9	9.2	12.8	3.6	2.4
Qualifications: NVQ or HND or HNC or equivalent	2.9	3.5	5.9	-2.4	-1.1
Breast cancer (self-reported)	2.9	3.4	4.5	-2.1	-1.5
Qualifications: CSEs or equivalent	2.8	3.7	5.0	-2.2	-1.5
Pulse rate	2.8	4.7	5.5	2.3	2.0
Suffer from ‘nerves’	2.8	4.4	6.9	-2.6	-1.3
Financial situation satisfaction	2.8	3.5	5.4	-2.3	-1.2
Ulcerative Colitis (UC)	2.7	5.2	6.1	2.5	2.0
Coronary Artery Disease (CAD)	2.7	3.3	4.6	-1.4	-2.1
Current tobacco smoking	2.6	4.3	7.3	-2.7	-1.2
Average weekly fortified wine intake	2.6	3.0	3.1	1.8	1.7
Medication: Ramipril	2.6	3.3	3.6	1.9	1.7
Exposure to tobacco smoke at home	2.6	2.9	4.7	-2.2	-1.0
Arm fat percentage (left)	2.6	10.2	13.0	-3.6	-2.7
Pain experienced in last month	2.6	4.3	5.5	2.4	1.7
Trunk fat percentage	2.5	10.2	11.7	-3.4	-2.9
Qualifications: A levels/AS levels or equivalent	2.5	5.5	7.0	2.6	2.0
Medication: Aspirin	2.5	3.2	4.1	2.0	1.5
Qualifications: None of the above	2.4	5.2	6.1	-2.1	-2.5
Overall health rating	2.4	5.2	6.5	-2.6	-2.0
Knee pain experienced in last month	2.4	3.7	6.3	-2.5	-1.1
Number of self-reported non-cancer illnesses	2.4	4.1	6.6	-2.6	-1.3
Prostate Cancer	2.3	3.2	3.3	-1.8	-1.8
Glaucoma (self-reported)	2.3	2.7	3.0	-1.5	-1.7
Angina (self-reported)	2.3	3.1	4.7	-1.2	-2.2
Diabetes diagnosed by doctor	2.3	3.8	4.1	-2.0	-1.9
Ever depressed for a whole week	2.3	2.8	3.0	1.6	1.7
Medication: Ventolin 100micrograms inhaler	2.2	2.8	3.4	-1.9	-1.5
Seen a psychiatrist for nerves, anxiety, tension or depression	2.2	2.9	3.2	-1.8	-1.6
Basal cell carcinoma (self-reported)	2.2	2.7	2.7	1.6	1.6
Arm fat mass (right)	2.1	8.8	11.3	-3.4	-2.5
Commuting to job workplace: Walk	2.0	2.1	2.6	1.6	1.3
Qualifications: O levels/GCSEs or equivalent	1.9	3.1	3.8	1.5	1.9
Whole body fat mass	1.9	8.1	9.6	-3.1	-2.6
Medication: Aspirin	1.9	2.5	3.2	1.8	1.3
Angina	1.8	2.4	3.5	-1.1	-1.9
Supplements: Zinc	1.8	2.0	3.3	-1.8	-0.8
Lung cancer (father)	1.8	2.1	3.1	-1.8	-1.0
Father’s age at death	1.7	2.3	2.3	1.5	1.5
Happiness	1.7	2.0	2.3	1.3	1.5
Reason for reducing amount of alcohol drunk: Health precaution	1.7	2.0	3.2	1.8	0.9
Hand grip strength (left)	1.6	4.2	5.4	1.8	2.3
Trunk fat mass	1.6	6.7	8.3	-2.9	-2.3
Nervous feelings	1.6	3.1	3.1	1.7	1.8
Diabetes (self-reported)	1.6	2.4	3.1	-1.8	-1.3
Shortness of breath walking on level ground	1.6	1.9	2.1	1.4	1.3
Smoking status: Previous	1.6	2.4	3.2	-1.3	-1.8
Mother’s age at death	1.6	2.0	3.0	1.0	1.7
Supplements: Fish oil (including cod liver oil)	1.6	2.1	3.0	-1.7	-1.1
High cholesterol (Self-reported)	1.6	2.8	4.1	-2.0	-1.2
Neuroticism (Nagel 2018)	1.5	3.5	4.0	1.8	2.0
Bipolar Disorder (2011)	1.5	1.5	1.6	1.3	1.1
Mouth/teeth dental problems: Loose teeth	1.5	1.8	3.0	-1.7	-0.7
Financial difficulties in last 2 years	1.4	1.9	3.1	-1.8	-0.8
Heart disease (mother)	1.4	1.7	2.7	0.8	1.6
Illnesses of siblings: Diabetes	1.4	1.8	2.6	-1.6	-0.9
Ever had stillbirth, spontaneous miscarriage or termination	1.4	1.5	1.6	1.3	1.2
Mineral and other dietary supplements	1.4	1.9	2.6	1.6	1.1
Major Depression (MDD)	1.3	1.6	2.1	-1.0	-1.5
Bilateral oophorectomy (both ovaries removed)	1.3	1.5	2.0	-1.4	-1.1
Number of incorrect matches in round	1.3	2.1	2.2	1.4	1.5
Ever unenthusiastic/disinterested for a whole week	1.3	1.6	2.1	1.1	1.5
Medication: Seretide 50 evohaler	1.3	1.5	1.8	-1.1	-1.3
Number of full sisters	1.3	1.6	2.5	-0.8	-1.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.3	1.5	2.0	1.4	1.0
Forced expiratory volume in 1-second (FEV1), predicted	1.3	2.7	4.3	2.1	1.0
Average weekly red wine intake	1.3	2.0	2.8	-1.7	-1.1
Arm fat mass (left)	1.3	5.3	7.2	-2.7	-1.9
Other serious medical condition/disability diagnosed by doctor	1.2	1.5	2.7	-1.6	-0.6
Townsend deprivation index at recruitment	1.2	1.6	2.4	-1.5	-0.9
Had other major operations	1.2	1.4	1.8	-1.0	-1.3
Neuroticism score	1.2	2.5	3.1	1.4	1.8
Noisy workplace	1.2	1.5	2.1	-1.4	-0.9
Prospective memory result	1.2	1.4	1.7	1.1	1.3
Illnesses of father: None of the above (group 1)	1.2	1.5	2.3	-0.9	-1.5
Alzheimer’s Disease (including proxy)	1.1	1.6	1.9	-1.2	-1.4
Irritable Bowel Disease (IBD)	1.1	2.6	3.5	1.9	1.3
Heel T-Score	1.1	8.4	11.4	3.4	2.3
Type 2 Diabetes (T2D) (2018)	1.1	2.1	2.9	-1.7	-1.2
Number of treatments/medications taken	1.1	2.0	2.1	-1.4	-1.4
Medication: Lansoprazole	1.1	1.2	1.8	0.8	1.3
Medication: Omeprazole	1.1	1.3	2.2	-1.5	-0.7
Back pain experienced in last month	1.1	1.6	2.5	-1.6	-0.8
Wears glasses or contact lenses	1.1	1.3	1.8	-1.4	-0.9
Medication: Blood pressure	1.1	2.0	2.3	1.5	1.3
Alzheimer’s Disease (in father)	1.0	1.1	1.6	-0.8	-1.2
Systolic blood pressure, automated reading	1.0	2.8	4.6	-2.1	-1.0
Waist circumference	1.0	3.7	4.3	-2.1	-1.8
Neck or shoulder pain in last month	1.0	1.4	1.5	-1.2	-1.2
Leg fat-free mass (right)	1.0	5.2	6.4	2.0	2.5
Leg predicted mass (right)	1.0	5.2	6.3	2.0	2.5
Hearing aid user	1.0	1.1	1.1	1.0	1.1
Medication: Atorvastatin	1.0	1.2	2.2	-0.4	-1.5
Unable to work because of sickness or disability	1.0	1.3	1.9	-1.4	-0.8
Blood Eosinophil Count	0.9	7.0	10.6	-1.9	-3.2
Allergy or Eczema	0.9	2.3	3.5	-1.9	-1.0
Lung FVC	0.9	4.8	5.3	-2.1	-2.3
Stomach or abdominal pain in last month	0.9	1.1	1.8	-0.6	-1.3
Illnesses of siblings	0.9	1.2	1.7	-0.8	-1.3
Impedance of arm (left)	0.9	4.2	6.4	2.5	1.4
Comparative body size at age 10	0.9	2.5	4.8	-2.2	-0.5
Emphysema/chronic bronchitis	0.9	1.1	1.4	-0.9	-1.2
Family relationship satisfaction	0.9	1.1	2.0	0.4	1.4
Medication: Bendroflumethiazide	0.9	1.3	1.5	1.1	1.2
Eye problems/disorders: Diabetes related eye disease	0.8	0.9	1.3	1.1	0.7
Hand grip strength (right)	0.8	2.2	2.7	1.4	1.6
Medication: Atenolol	0.8	1.0	1.2	0.9	1.1
Alcohol intake versus 10 years previously	0.8	1.3	1.4	1.2	1.1
Chronic bronchitis/emphysema (mother)	0.8	0.9	1.0	-1.0	-0.9
Handedness (chirality/laterality): Left-handed	0.8	1.0	1.5	0.7	1.2
Qualifications: nursing, teaching	0.8	1.2	2.2	1.5	0.4
Fractured/broken bones in last 5 years	0.8	1.0	1.3	0.9	1.1
Alzheimer’s Disease (in mother)	0.7	0.8	0.9	-0.9	-0.9
Crohns Disease (2012)	0.7	1.1	1.3	0.9	1.1
Multivitamins +/- minerals	0.7	0.9	1.7	-1.3	-0.4
Allergy	0.7	1.7	3.1	1.7	0.5
Illnesses of mother	0.7	0.9	1.5	1.2	0.6
Eye problems/disorders: None of the above	0.7	0.8	1.2	-1.1	-0.7
Medication: Allopurinol	0.7	0.9	1.3	-0.8	-1.1
Alcohol intake frequency.	0.7	1.7	1.8	1.4	1.2
Average weekly champagne plus white wine intake	0.7	0.9	1.5	1.2	0.6
Risk taking	0.7	1.0	1.3	0.9	1.1
Ever had prostate specific antigen (PSA) test	0.7	0.8	1.2	-0.7	-1.1
Medication: Omeprazole (e.g. Zanprol)	0.7	0.8	1.4	-1.2	-0.5
Intelligence (Savage-Jansen 2018)	0.6	1.8	2.0	1.4	1.3
Medication: Metformin	0.6	0.8	1.0	-1.0	-0.8
Impedance of leg (right)	0.6	2.9	4.9	-0.9	-2.2
Worrier / anxious feelings	0.6	1.1	1.6	0.8	1.3
Asthma	0.6	1.2	2.1	-1.4	-0.6
Tense / ‘highly strung’	0.6	0.9	1.3	0.7	1.1
Mean time to correctly identify matches	0.6	1.1	2.2	1.5	0.3
Chest pain or discomfort	0.6	0.9	0.9	-1.0	-0.9
Medication for cholesterol	0.6	0.9	1.2	1.1	0.8
Asthma (self-reported)	0.6	1.3	2.2	-1.5	-0.6
Tinnitus: Yes, now most or all of the time	0.6	0.7	1.4	1.2	0.1
Bipolar Disorder (2018)	0.5	0.8	1.2	0.7	1.1
Bipolar Disorder or Schizophrenia	0.5	1.2	1.6	0.9	1.3
Ovarian Cancer	0.5	0.7	0.8	-0.7	-0.9
Leg fat-free mass (left)	0.5	2.7	3.5	1.4	1.9
Heel bone mineral density (BMD) T-score, automated (left)	0.5	1.1	1.8	1.4	0.6
Hayfever, allergic rhinitis or eczema	0.5	1.1	2.0	-1.4	-0.5
Leg predicted mass (left)	0.5	2.7	3.4	1.4	1.8
Medication: Simvastatin	0.5	0.7	1.4	-1.2	-0.3
Hip circumference	0.5	2.1	3.2	-1.8	-1.0
Frequency of tiredness / lethargy in last 2 weeks	0.5	0.8	1.0	-1.0	-0.8
Birth weight of first child	0.5	1.0	1.9	1.4	0.2
Ever had bowel cancer screening	0.5	0.6	1.1	1.1	0.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.5	1.0	1.7	-1.3	-0.5
Whole body water mass	0.5	3.0	3.9	1.5	2.0
Illnesses of father: High blood pressure	0.5	0.6	1.1	0.2	1.1
Worry (Nagel 2018)	0.4	0.9	1.0	0.9	1.0
Verbal and Numeric Reasoning (VNR)	0.4	1.0	1.4	1.2	0.8
Primary Biliary Cirrhosis	0.4	0.6	1.2	-1.1	-0.2
Systolic Blood Pressure	0.4	2.2	4.0	-2.0	-0.5
Age when periods started (menarche)	0.4	1.0	1.7	-0.6	-1.3
Chronic bronchitis/emphysema (father)	0.4	0.4	0.6	0.6	0.8
Impedance of leg (left)	0.4	1.9	3.3	-0.7	-1.8
Alcohol usually taken with meals	0.4	0.7	0.8	0.8	0.9
Fluid intelligence score	0.4	0.8	1.1	1.0	0.7
Trunk fat-free mass	0.4	2.1	2.9	1.1	1.7
Number of live births	0.4	0.6	1.3	-1.1	-0.1
Medication: Cholesterol lowering	0.4	0.6	0.8	-0.7	-0.9
Trunk predicted mass	0.4	2.1	2.8	1.2	1.7
Age at first live birth	0.4	0.8	1.2	1.1	0.6
Arm predicted mass (right)	0.4	2.0	2.5	1.2	1.6
Whole body fat-free mass	0.4	2.5	3.3	1.3	1.8
Osteoporosis (self-reported)	0.4	0.5	0.6	0.8	0.7
Vascular/heart problems diagnosed by doctor	0.4	1.1	1.1	-1.0	-1.1
Depressed Affect (Nagel 2018)	0.3	0.6	0.7	0.8	0.8
Reaction Time	0.3	0.6	1.1	1.1	0.4
HDL Cholesterol	0.3	0.4	0.7	-0.8	0.5
Schizophrenia (2014)	0.3	0.7	0.9	0.9	0.7
Blood White Count	0.3	2.6	4.5	-0.8	-2.1
Relative age of first facial hair	0.3	0.7	0.8	0.8	0.9
Medication: Co-codamol	0.3	0.4	0.5	-0.7	-0.6
High blood pressure	0.3	0.7	0.8	0.8	0.9
Diverticular disease/diverticulitis (self-reported)	0.3	0.3	0.6	0.8	0.3
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.4	0.7	0.4	0.8
Hayfever/allergic rhinitis (self-reported)	0.3	0.4	0.8	-0.9	-0.2
Weight	0.3	1.4	2.0	-1.4	-0.9
Impedance of arm (right)	0.3	1.2	2.4	1.6	0.2
Time employed in main current job	0.3	0.4	0.8	0.9	0.2
Peak expiratory flow (PEF)	0.3	0.6	0.9	-0.9	0.5
Medication: Paracetamol	0.3	0.4	0.6	-0.6	-0.8
Arm fat-free mass (right)	0.3	1.5	2.1	0.9	1.4
Migraine (self-reported)	0.3	0.3	0.6	0.1	0.8
Illnesses of father: Heart disease	0.3	0.3	0.6	0.3	0.8
Loneliness, isolation	0.3	0.5	0.9	0.9	0.2
Long-standing illness, disability or infirmity	0.3	0.4	0.8	-0.9	-0.0
Medication: Gliclazide	0.3	0.3	0.4	-0.7	0.4
Medication: Paracetamol	0.3	0.5	0.6	-0.6	-0.8
Irritability	0.3	0.5	1.0	0.1	1.0
Alcohol drinker status: Previous	0.3	0.4	0.4	0.6	0.6
Depression (Nagel 2018)	0.2	0.3	0.5	0.7	0.2
Schizophrenia (2018)	0.2	0.4	0.5	0.6	0.7
Schizophrenia vs Biploar Disorder	0.2	0.2	0.4	0.1	-0.7
Cardiovascular Disease	0.2	0.8	1.4	0.3	1.2
Sensitivity / hurt feelings	0.2	0.3	0.4	0.5	0.7
Ever used hormone-replacement therapy (HRT)	0.2	0.2	0.3	-0.5	-0.4
Medication for hormone replacement therapy	0.2	0.2	0.3	-0.3	-0.5
Vitamin and mineral supplements	0.2	0.3	0.5	0.7	-0.1
Forced vital capacity (FVC)	0.2	0.9	1.3	1.2	0.7
Pulse wave Arterial Stiffness index	0.2	0.3	0.5	0.0	0.7
Breastfed as a baby	0.2	0.2	0.3	0.6	0.2
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.4	0.6	-0.3	-0.8
Pulse wave reflection index	0.2	0.2	0.4	-0.7	-0.2
Ever highly irritable/argumentative for 2 days	0.2	0.3	0.5	-0.7	0.1
Blood clot in the leg (DVT)	0.2	0.3	0.6	-0.1	0.7
Gout (self-reported)	0.2	0.3	0.3	-0.6	-0.5
Medication: Amlodipine	0.2	0.2	0.3	0.4	-0.5
High blood pressure (siblings)	0.2	0.3	0.6	0.1	0.8
Forced vital capacity (FVC), Best measure	0.2	0.9	1.5	1.2	0.6
Medication: Ibuprofen	0.2	0.2	0.4	0.6	0.2
Commuting to job workplace: Car/motor vehicle	0.2	0.2	0.4	0.6	0.0
Illness, injury, bereavement, stress in last 2 years	0.2	0.2	0.4	-0.2	-0.6
Supplements: Vitamin C	0.2	0.3	0.6	-0.0	0.7
Mood swings	0.2	0.4	0.6	-0.8	0.4
Miserableness	0.2	0.4	0.7	-0.3	0.8
Medication: Lisinopril	0.2	0.3	0.6	0.7	0.1
Basal metabolic rate	0.2	1.0	1.5	0.7	1.2
Average weekly beer plus cider intake	0.2	0.3	0.4	-0.5	-0.6
Heart attack/myocardial infarction (self-reported)	0.2	0.2	0.5	0.7	0.0
Deep venous thrombosis (DVT) (self-reported)	0.2	0.2	0.4	0.1	0.6
LDL Cholesterol	0.1	0.2	0.3	-0.5	-0.4
Lupus	0.1	0.1	0.2	0.4	0.3
Waist Hip Ratio (WHR)	0.1	0.6	1.1	1.0	-0.5
Chronotype (morning person)	0.1	0.3	0.7	0.8	0.0
Hair Pigment	0.1	3.2	4.1	-1.5	-2.0
Frequency of depressed mood in last 2 weeks	0.1	0.1	0.1	-0.3	-0.2
Fed-up feelings	0.1	0.1	0.2	-0.4	0.3
Frequency of unenthusiasm / disinterest in last 2 weeks	0.1	0.2	0.3	-0.2	-0.5
Relative age voice broke	0.1	0.1	0.1	-0.3	-0.3
Serious illness, injury or assault to yourself	0.1	0.2	0.3	0.6	0.2
High blood pressure (mother)	0.1	0.2	0.3	-0.3	0.5
Heart attack	0.1	0.1	0.2	0.4	-0.3
Serious illness, injury or assault of a close relative in last 2 years	0.1	0.2	0.2	-0.5	-0.3
Medication: Ibuprofen (e.g. Nurofen)	0.1	0.2	0.2	0.4	0.4
Depression (self-reported)	0.1	0.2	0.3	0.6	0.2
Loud music exposure frequency	0.1	0.1	0.3	-0.0	0.5
Headache pain in last month	0.1	0.2	0.2	-0.4	-0.4
Number of children fathered	0.1	0.1	0.2	-0.5	-0.2
Pulse wave peak to peak time	0.1	0.2	0.2	0.3	-0.5
Health satisfaction	0.1	0.1	0.1	-0.3	0.4
Medication for pain relief, constipation, heartburn	0.1	0.1	0.1	0.3	0.3
Hypertension (Self-reported)	0.1	0.4	0.5	0.5	0.7
Mouth/teeth dental problems: Mouth ulcers	0.1	0.2	0.2	0.4	0.4
Ever taken oral contraceptive pill	0.1	0.2	0.2	0.4	-0.4
Commuting to job workplace: Public transport	0.1	0.1	0.1	0.4	0.3
Alcohol drinker status: Never	0.1	0.1	0.1	0.4	0.3
Arm fat-free mass (left)	0.1	0.5	0.7	0.5	0.8
Commuting to job workplace: Cycle	0.1	0.2	0.3	-0.5	0.2
Cholesterol lowering medication	0.1	0.2	0.4	-0.6	0.1
Pack years of smoking	0.1	0.2	0.3	-0.5	-0.3
Impedance of whole body	0.1	0.4	0.8	0.9	-0.3
Crohns Disease (2017)	0.0	0.1	0.1	0.3	-0.1
Mean Putamen Volume	0.0	0.0	0.0	0.0	0.1
Triglycerides	0.0	0.0	0.0	-0.0	-0.1
Respiratory disease	0.0	0.0	0.0	0.1	0.2
Tanning	0.0	0.4	0.7	-0.8	-0.5
Pack years adult smoking proportion	0.0	0.1	0.1	-0.4	0.1
Hair/balding pattern: Pattern 2	0.0	0.0	0.1	-0.1	0.3
Heel bone mineral density (BMD) T-score, automated (right)	0.0	0.0	0.0	0.1	0.1
Pain all over the body in last month	0.0	0.0	0.1	-0.0	-0.3
Falls in the last year	0.0	0.0	0.1	0.3	-0.1
Forced expiratory volume in 1-second (FEV1)	0.0	0.1	0.2	-0.3	0.4
Forced expiratory volume in 1-second (FEV1), Best measure	0.0	0.0	0.0	-0.1	0.2
Hair/balding pattern: Pattern 4	0.0	0.1	0.1	0.1	0.3
Medication for cholesterol, blood pressure or diabetes	0.0	0.0	0.0	-0.0	-0.1
Birth weight	0.0	0.0	0.0	0.1	-0.1
Number of full brothers	0.0	0.0	0.0	-0.1	-0.1
Medication: Blood pressure	0.0	0.1	0.1	0.2	0.3
Age at last live birth	0.0	0.0	0.1	0.3	0.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.0	0.1	0.1	-0.3	-0.2
Pain type(s) experienced in last month: Hip pain	0.0	0.0	0.1	-0.1	0.3
Diastolic blood pressure, automated reading	0.0	0.0	0.1	-0.3	-0.2
Supplements: Calcium	0.0	0.0	0.0	-0.2	0.2
Arm predicted mass (left)	0.0	0.2	0.4	0.2	0.6

Hub : Genes

RPS15AP10

Models

Trait associations