Best TWAS P=1.33e-09 · Best GWAS P=2.46e-13 conditioned to 0.00532
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | CRTAC1 | 0.06 | 0.04 | lasso | 2 | 0.05 | 3.6e-07 | 4.2 | -6.1 | 1.3e-09 | 0.63 | 0.44 | 0.54 | TRUE |
| 2 | CommonMind | Brain Pre-frontal Cortex | GOLGA7B | 0.07 | 0.00 | enet | 23 | 0.04 | 1.3e-05 | -1.6 | -5.2 | 1.5e-07 | 0.46 | 0.59 | 0.05 | TRUE |
| 3 | GTEx | Nerve Tibial | R3HCC1L | 0.06 | 0.07 | enet | 8 | 0.05 | 1.1e-04 | -5.3 | -5.5 | 2.9e-08 | 0.37 | 0.78 | 0.01 | TRUE |