Hub : Genes

CRTAC1

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0570	0.0230	5.7e-03	0.035	0.020	0.049	0.033	0.054	3.4e-05	1.5e-03	1.1e-06	6.7e-05	3.6e-07
2	GTEx	Heart Atrial Appendage	0.3900	0.0880	1.7e-03	0.130	NA	0.147	NA	0.194	1.9e-06	NA	4.1e-07	NA	4.2e-09
3	GTEx	Heart Left Ventricle	0.4197	0.0614	2.6e-08	0.357	NA	0.319	NA	0.339	6.4e-20	NA	1.6e-17	NA	9.4e-19
4	GTEx	Nerve Tibial	0.1429	0.0575	5.1e-03	0.069	NA	0.043	NA	0.056	1.3e-05	NA	5.1e-04	NA	8.1e-05
5	ROSMAP	Brain Pre-frontal Cortex	0.0877	0.0290	2.3e-04	0.059	0.033	0.040	0.038	0.051	4.8e-08	4.0e-05	5.7e-06	9.3e-06	3.3e-07
6	TCGA	Breast Invasive Carcinoma	0.0531	0.0180	2.2e-05	0.045	0.014	0.039	NA	0.043	1.3e-09	4.9e-04	1.4e-08	NA	3.0e-09
7	TCGA	Kidney Renal Clear Cell Carcinoma	0.1092	0.0364	7.1e-05	0.075	0.046	0.062	NA	0.061	8.7e-09	5.8e-06	1.8e-07	NA	1.9e-07
8	TCGA	Liver Hepatocellular Carcinoma	0.1200	0.0490	5.3e-03	0.083	0.004	0.032	NA	0.063	9.9e-05	1.9e-01	1.2e-02	NA	6.7e-04
9	TCGA	Rectum Adenocarcinoma	0.2930	0.1070	7.0e-03	0.037	0.056	0.110	NA	0.047	4.8e-02	1.9e-02	1.6e-03	NA	3.0e-02
10	TCGA	Stomach Adenocarcinoma	0.1480	0.0470	8.7e-06	0.143	0.072	0.106	NA	0.127	1.7e-10	7.1e-06	4.2e-08	NA	2.0e-09

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10
Bipolar Disorder (2018)	1.0	1.6	2.9	1.3	-0.7	-0.1	-1.6	1.0	-1.7	-1.0	-1.7	-1.3	-1.5
Bipolar Disorder or Schizophrenia	0.3	0.8	2.6	0.4	-0.3	0.0	-1.2	0.1	-1.2	-0.6	-1.0	-1.6	-0.9
Depressed Affect (Nagel 2018)	0.3	0.6	1.2	-0.2	1.0	0.7	0.8	0.6	0.9	1.1	1.0	-0.2	0.6
Depression (Nagel 2018)	0.3	0.4	1.0	0.1	0.9	0.6	0.6	-0.1	0.6	0.6	1.0	0.6	0.8
Intelligence (Savage-Jansen 2018)	0.6	2.0	10.7	3.3	-0.7	-0.4	-0.6	2.6	-0.7	-0.3	-0.8	0.3	-0.6
Neuroticism (Nagel 2018)	1.1	2.5	3.9	1.3	1.3	0.4	1.9	1.6	1.9	1.8	2.0	0.8	1.9
Schizophrenia (2018)	0.1	0.2	1.1	-0.5	0.1	0.1	-0.2	-0.7	-0.2	-0.1	0.1	-1.1	-0.0
Schizophrenia vs Biploar Disorder	1.1	1.4	3.9	-2.0	-0.4	-1.2	1.2	-1.2	1.2	0.9	1.2	0.8	1.1
Worry (Nagel 2018)	0.4	0.8	2.8	1.7	-0.3	-0.8	0.6	1.4	0.7	0.7	0.8	-0.5	0.6
Alzheimer’s Disease (in mother)	0.8	0.9	1.9	-0.2	-1.4	-1.2	-1.0	-0.9	-0.9	-0.8	-1.2	0.4	-0.9
Alzheimer’s Disease (in father)	2.6	2.8	6.9	0.6	-2.1	-1.4	-1.9	1.0	-1.8	-1.4	-2.6	-0.5	-2.0
Alzheimer’s Disease (including proxy)	0.6	0.8	3.0	-0.2	-1.1	-0.7	-0.9	-0.2	-0.9	-0.9	-1.7	0.5	-0.8
Crohns Disease (2017)	0.5	1.0	5.0	-1.4	-1.1	-1.4	-0.0	-0.3	-0.0	0.4	0.2	2.2	0.4
Irritable Bowel Disease (IBD)	0.3	0.6	2.0	0.0	-1.4	-1.4	-0.5	0.9	-0.4	-0.0	-0.3	1.0	-0.3
Ulcerative Colitis (UC)	0.5	0.9	1.7	0.8	-1.2	-0.6	-0.9	1.3	-0.8	-0.7	-1.0	-0.7	-1.2
Major Depression (MDD)	1.1	1.3	5.2	2.1	-0.8	-1.2	0.3	2.3	0.5	0.9	0.4	0.6	0.3
Reaction Time	0.9	1.8	3.6	-1.6	-1.3	-0.8	-1.1	-1.9	-1.0	-1.4	-1.4	-1.2	-1.3
Verbal and Numeric Reasoning (VNR)	0.3	0.6	2.5	1.6	-0.4	-0.8	0.2	1.2	0.0	0.5	0.3	1.0	0.3
Breast Cancer	0.2	0.5	0.8	0.5	0.9	0.8	0.6	0.6	0.7	0.7	0.9	0.3	0.6
Ovarian Cancer	0.7	0.9	1.6	-0.9	-0.6	0.0	-1.2	-0.1	-1.2	-1.1	-1.1	-1.3	-1.2
Prostate Cancer	0.3	0.4	1.3	1.2	-0.6	-0.5	-0.0	0.4	0.2	0.4	-0.1	-1.0	-0.5
Age at First Birth	0.5	0.7	2.0	0.3	1.4	1.4	0.8	-0.9	0.7	0.1	0.4	0.3	0.8
Bipolar Disorder (2011)	1.9	1.8	7.0	2.7	-0.8	-0.3	-0.9	2.6	-0.9	-0.6	-0.9	0.0	-0.8
Body Mass Index (BMI) (2010)	0.6	0.8	3.5	-1.9	-0.9	-0.7	-0.8	-1.2	-0.8	-0.1	-0.2	-0.4	-0.7
Coronary Artery Disease (CAD)	0.5	0.6	1.7	0.2	-1.1	-1.3	-0.4	0.7	-0.4	-0.1	-1.0	0.7	-0.4
Crohns Disease (2012)	0.4	0.7	3.9	-0.2	-0.4	-0.7	0.1	1.3	0.1	0.3	0.0	2.0	0.3
Mean Putamen Volume	0.7	0.8	3.3	-0.6	-1.2	-1.8	0.4	0.2	0.3	-0.0	0.6	1.3	0.7
Fasting Glucose	0.2	0.2	0.7	0.1	-0.8	-0.6	-0.5	0.0	-0.6	-0.5	-0.5	0.0	-0.5
HbA1C	0.4	0.4	1.3	0.9	-0.8	-1.1	0.4	1.0	0.4	0.5	0.1	-0.0	0.3
HDL Cholesterol	0.2	0.3	1.6	0.8	-0.4	-0.3	-0.4	1.2	-0.5	0.0	0.1	-0.2	-0.2
LDL Cholesterol	0.8	1.2	3.0	-0.3	0.6	0.0	1.5	-0.2	1.5	1.2	0.9	1.7	1.5
Lupus	2.0	3.0	7.0	2.6	-1.4	-2.3	1.1	1.9	1.2	1.9	1.1	1.7	1.0
Neuroticism (2016)	0.3	0.5	1.8	1.1	-0.7	-0.6	-0.5	1.3	-0.5	-0.2	0.2	-0.3	-0.4
Primary Biliary Cirrhosis	0.0	0.1	0.1	-0.3	-0.2	-0.0	-0.3	0.0	-0.3	-0.3	-0.0	0.1	-0.3
Rheumatoid Arthritis	0.2	0.3	1.0	-0.2	-0.8	-0.5	-0.5	1.0	-0.6	-0.7	-0.4	-0.2	-0.6
Schizophrenia (2014)	0.1	0.3	0.9	-0.4	-0.3	-0.9	0.6	-0.4	0.6	0.7	0.3	0.3	0.8
Triglycerides	1.8	2.9	6.3	-0.8	-0.1	-1.3	1.9	-0.2	2.0	2.3	2.0	2.5	2.0
Type 2 Diabetes (T2D) (2012)	3.4	3.9	6.8	0.0	2.6	2.3	2.2	0.7	2.2	2.0	1.7	2.3	2.2
Ulcerative Colitis	0.2	0.2	0.6	0.4	-0.0	-0.1	0.4	0.6	0.5	0.6	0.4	0.8	0.2
Blood Eosinophil Count	0.5	3.6	7.4	-2.7	-1.0	-0.2	-1.6	-2.7	-1.7	-2.7	-2.2	-0.9	-1.5
Blood Platelet Count	0.2	2.8	8.8	1.2	-3.0	-2.7	-1.4	1.6	-1.3	-0.9	-0.7	-0.9	-1.4
Blood Red Count	0.0	0.4	2.1	-1.4	0.1	-0.0	-0.3	-0.9	-0.3	-0.4	-0.5	0.5	-0.1
Blood White Count	0.6	4.3	6.2	-2.5	-1.4	-0.5	-2.4	-2.4	-2.4	-2.4	-2.1	-1.6	-2.2
Heel T-Score	0.1	0.5	2.9	1.7	-0.0	0.2	0.2	0.9	0.3	-0.3	-0.5	-0.8	-0.1
BMI	1.8	10.2	67.9	-8.2	0.3	0.4	-0.2	-5.5	-0.2	-1.1	-1.2	0.1	-0.3
Height	0.2	3.6	10.4	3.2	-0.3	0.6	-1.9	2.9	-2.0	-1.0	-1.8	-0.6	-2.0
Waist Hip Ratio (WHR)	0.4	1.6	3.4	1.1	-1.5	-1.0	-1.8	0.4	-1.8	-0.8	-0.9	0.9	-1.5
Systolic Blood Pressure	0.4	1.8	4.0	-0.3	0.9	-0.1	1.6	-0.0	1.6	2.0	1.9	1.6	1.5
Smoking Status	1.0	2.5	9.9	-3.1	-0.2	0.7	-1.4	-2.0	-1.3	-1.5	-1.4	-1.1	-1.2
Allergy or Eczema	0.1	0.3	0.6	-0.0	-0.7	-0.4	-0.7	-0.0	-0.7	-0.7	-0.8	-0.4	-0.6
Cardiovascular Disease	0.4	1.5	7.6	-2.8	0.4	-0.2	0.8	-2.0	0.6	0.2	0.9	0.3	1.0
Hypothyroidism (self reported)	0.1	0.3	1.2	0.6	0.1	0.0	0.3	1.1	0.3	-0.0	0.7	-0.2	0.5
Respiratory disease	0.3	0.6	1.3	0.5	-0.4	-1.1	0.8	1.1	0.8	0.8	0.6	-0.2	0.7
Type 2 Diabetes (T2D) (2018)	0.1	0.1	0.6	0.1	0.1	-0.3	0.4	0.1	0.3	0.1	0.3	0.2	0.7
Lung FEV1/FVC ratio	0.1	0.7	3.2	-0.0	-1.2	-1.8	0.2	0.7	0.3	0.8	0.3	0.8	0.1
Lung FVC	0.1	0.5	2.2	1.5	0.0	-0.6	1.0	-0.1	0.8	0.2	0.5	-0.2	1.0
Neuroticism	0.6	1.5	2.8	0.9	0.9	0.2	1.6	1.5	1.5	1.0	1.7	-0.3	1.6
Chronotype (morning person)	0.1	0.2	1.2	-0.6	-0.1	-0.1	-0.1	-1.1	-0.1	-0.3	-0.5	0.3	-0.0
Hair Pigment	0.0	0.5	1.8	-0.8	0.5	0.4	0.7	-1.4	0.9	0.7	0.5	0.1	0.4
Tanning	0.2	1.9	5.3	2.0	-0.7	-0.1	-1.1	2.3	-1.2	-0.6	-0.7	-2.0	-1.2
Hand grip strength (left)	1.0	2.7	7.1	2.7	0.3	-0.7	1.4	1.4	1.3	1.5	1.5	2.5	1.6
Number of treatments/medications taken	0.7	1.3	4.1	-2.0	-0.2	0.2	-0.9	-1.7	-1.0	-1.6	-0.8	-0.5	-0.5
Average weekly spirits intake	1.1	1.3	2.6	-1.4	-0.5	-1.3	1.0	-0.6	1.0	1.6	1.4	1.3	1.0
Sensitivity / hurt feelings	2.3	4.0	6.9	1.3	1.1	-0.2	2.6	1.8	2.6	2.4	2.6	1.0	2.5
Frequency of depressed mood in last 2 weeks	0.2	0.2	0.5	-0.1	0.7	0.6	0.4	-0.1	0.5	0.7	0.4	0.3	0.3
Hearing difficulty/problems: Yes	0.7	1.1	3.2	-1.7	1.5	1.8	0.3	-1.3	0.4	-0.2	0.2	-0.3	0.0
Relative age of first facial hair	0.3	0.5	2.1	-0.7	1.2	1.5	0.0	-0.9	0.0	-0.1	-0.1	0.5	0.2
Other serious medical condition/disability diagnosed by doctor	1.1	1.5	5.0	-2.0	0.1	0.8	-1.0	-2.2	-1.0	-0.8	-1.0	-0.1	-1.1
Ever used hormone-replacement therapy (HRT)	0.5	0.6	1.8	-0.3	1.0	0.9	0.8	0.7	0.8	0.4	0.0	1.3	0.7
Ever had hysterectomy (womb removed)	2.1	2.3	4.1	-2.0	0.4	1.6	-1.6	-1.1	-1.6	-1.9	-1.2	-1.6	-1.6
Systolic blood pressure, automated reading	0.4	1.1	4.2	-2.0	0.8	0.2	1.2	-1.2	1.2	0.7	0.7	0.5	0.9
Eye problems/disorders: Diabetes related eye disease	0.5	0.6	2.1	1.1	-0.7	-1.1	0.3	1.5	0.3	-0.1	-0.3	0.4	0.4
Angina	0.5	0.7	1.3	-0.7	0.8	0.2	1.0	-0.2	0.9	1.2	1.1	0.7	1.0
Medication for hormone replacement therapy	0.2	0.3	0.8	-0.8	0.4	0.7	0.1	-0.6	0.3	0.2	-0.1	-0.9	-0.3
Vitamin and mineral supplements	0.4	0.6	1.7	1.0	0.8	0.6	0.6	1.3	0.5	0.2	0.1	0.8	0.7
Supplements: Zinc	0.6	0.6	1.2	-0.3	1.1	1.1	0.5	-1.1	0.5	0.4	1.1	-0.9	0.5
Medication: Co-codamol	0.9	1.0	2.4	-0.2	1.1	0.7	1.1	-0.4	1.1	1.2	1.5	0.6	1.1
Medication: Metformin	0.3	0.4	1.2	-0.9	-0.4	-0.8	0.1	-0.8	0.0	0.2	-0.1	1.1	0.5
Diabetes (father)	1.5	1.8	7.6	-0.8	-0.8	-0.0	-1.2	-1.0	-1.1	-1.4	-1.1	-2.8	-1.5
Diabetes (mother)	0.2	0.3	0.6	-0.6	-0.2	-0.5	0.7	-0.6	0.8	0.3	0.4	-0.1	0.6
Severe depression (siblings)	0.4	0.5	1.1	-0.3	1.1	1.0	0.5	-0.5	0.6	0.7	0.9	-0.2	0.5
Pack years adult smoking proportion	1.1	1.6	6.9	-2.4	0.6	1.0	-0.5	-2.6	-0.5	-1.1	-0.9	-0.1	-0.4
Impedance of leg (right)	0.3	1.2	10.5	3.2	-0.4	-0.0	-0.5	0.9	-0.3	0.4	0.2	-0.4	-0.5
Leg fat-free mass (left)	0.3	1.8	12.1	-3.5	0.5	0.6	-0.4	-1.5	-0.4	-1.0	-1.2	0.4	-0.5
Trunk fat percentage	1.4	5.5	33.2	-5.8	0.2	0.7	-0.2	-4.2	-0.1	-1.4	-1.2	0.0	-0.4
Hand grip strength (right)	0.4	1.0	4.0	1.8	0.6	0.1	0.7	0.3	0.6	0.6	0.5	2.0	0.8
Townsend deprivation index at recruitment	1.5	2.0	3.8	0.2	-2.0	-1.2	-1.7	0.3	-1.6	-1.6	-1.8	-0.8	-1.7
Current tobacco smoking	0.6	0.9	2.5	-1.6	-0.0	0.4	-0.8	-0.8	-0.8	-1.1	-1.1	-1.2	-0.7
Average weekly fortified wine intake	0.2	0.2	1.3	0.2	-0.5	-0.1	-0.1	0.3	0.0	-0.3	-1.1	-0.2	-0.5
Maternal smoking around birth	1.5	2.1	4.6	-0.9	1.1	0.1	1.9	-0.8	1.9	1.1	1.3	2.1	2.0
Fed-up feelings	0.2	0.3	1.1	-0.3	-0.2	-0.7	0.5	0.3	0.6	1.1	0.6	0.3	0.3
Frequency of unenthusiasm / disinterest in last 2 weeks	0.1	0.1	0.3	-0.5	0.3	0.5	-0.2	-0.6	-0.2	0.3	0.3	0.5	-0.1
Relative age voice broke	0.3	0.5	1.5	1.2	1.0	1.1	0.2	0.8	0.2	-0.1	-0.2	0.5	0.3
Taking other prescription medications	0.1	0.2	0.4	-0.3	-0.2	-0.6	0.6	0.3	0.5	0.0	0.2	-0.0	0.7
Age when periods started (menarche)	1.4	3.4	14.7	3.6	-1.0	-0.8	-1.0	3.8	-1.0	-0.7	-0.6	-1.0	-0.9
Bilateral oophorectomy (both ovaries removed)	0.1	0.1	0.3	-0.1	0.2	0.6	-0.1	-0.2	0.0	0.1	-0.1	0.5	-0.2
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.7	1.1	0.9	0.8	0.5	1.0	0.9	1.1	1.0	0.2	0.6	0.7
Tinnitus: Yes, but not now, but have in the past	0.3	0.4	1.0	-0.1	0.0	-0.4	0.8	-0.2	0.8	0.7	1.0	-0.1	0.7
Qualifications: CSEs or equivalent	1.1	1.5	3.0	-1.7	1.6	1.1	1.4	-1.3	1.5	0.6	1.0	0.2	1.0
Serious illness, injury or assault to yourself	0.5	0.6	1.6	-0.0	-0.8	-0.8	-1.0	0.5	-1.1	-0.5	-0.6	1.3	-0.6
High blood pressure	0.5	1.3	6.4	-2.5	0.7	0.2	0.7	-2.1	0.5	-0.2	0.7	-0.1	0.7
Hayfever, allergic rhinitis or eczema	0.2	0.3	1.4	0.6	-1.0	-1.2	-0.1	0.5	-0.1	0.1	-0.4	0.1	-0.2
Multivitamins +/- minerals	0.1	0.2	0.8	-0.8	0.0	0.3	-0.2	-0.9	-0.1	-0.1	0.1	-0.3	-0.2
Stomach or abdominal pain in last month	1.1	1.4	2.8	-0.2	1.3	0.7	1.6	0.0	1.7	1.4	1.4	0.7	1.5
Supplements: Glucosamine	1.9	2.5	4.3	0.2	-2.1	-1.4	-2.0	0.1	-2.0	-1.7	-1.1	-1.7	-1.9
Diverticular disease/diverticulitis (self-reported)	0.1	0.1	0.2	-0.3	0.2	0.5	-0.2	0.5	-0.3	-0.4	-0.0	0.2	-0.0
Medication: Atenolol	0.5	0.6	1.7	0.2	-1.3	-1.0	-0.8	0.9	-0.8	-0.7	-0.6	0.6	-0.6
Medication: Levothyroxine sodium	0.0	0.1	0.2	0.0	0.1	0.1	0.3	-0.2	0.3	-0.3	0.3	0.3	0.4
Sitting height	0.6	3.9	11.9	1.9	-1.2	-0.4	-2.2	3.5	-2.1	-1.0	-2.5	-0.8	-2.3
Chronic bronchitis/emphysema (father)	0.1	0.1	0.5	-0.3	0.4	0.3	0.2	-0.7	0.1	-0.0	0.2	0.1	0.4
High blood pressure (mother)	2.6	3.7	8.0	-2.2	2.8	2.2	2.1	-1.3	2.1	1.5	1.3	1.0	2.0
Body mass index (BMI)	1.7	7.4	50.3	-7.1	0.8	0.4	0.9	-4.4	0.9	-0.4	-0.0	0.9	1.0
Impedance of leg (left)	0.4	1.8	15.5	3.9	-0.4	-0.1	-0.4	1.3	-0.2	0.4	0.4	-0.2	-0.4
Leg predicted mass (left)	0.3	1.8	11.9	-3.5	0.4	0.7	-0.4	-1.4	-0.5	-1.0	-1.3	0.3	-0.6
Trunk fat mass	1.2	5.2	32.6	-5.7	0.3	0.8	-0.3	-3.7	-0.2	-1.4	-1.4	0.3	-0.4
Waist circumference	1.2	4.5	28.2	-5.3	0.3	0.6	-0.5	-3.5	-0.5	-1.4	-1.2	0.7	-0.4
Number of incorrect matches in round	0.6	1.1	5.0	-1.9	-0.7	-0.6	-0.6	-2.2	-0.5	-0.2	-0.2	0.1	-0.7
Past tobacco smoking	0.2	0.4	2.2	1.5	-0.5	-0.7	0.2	0.7	0.2	-0.2	-0.3	0.1	-0.0
Alcohol usually taken with meals	0.4	0.7	1.8	-0.0	-0.2	0.6	-1.1	-0.2	-1.0	-0.8	-1.4	-0.8	-1.0
Nervous feelings	0.9	1.7	7.3	2.7	-1.2	-1.4	-0.0	2.3	-0.0	0.1	-0.2	-0.5	-0.0
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.6	1.7	-0.5	-1.3	-1.2	-0.9	-0.2	-0.8	-0.4	-0.6	-0.0	-0.7
Hearing difficulty/problems with background noise	0.1	0.2	0.6	0.4	0.2	-0.1	0.7	0.3	0.8	0.2	0.4	0.7	0.4
Hair/balding pattern: Pattern 2	0.9	1.1	3.7	0.8	0.2	0.9	-1.1	0.6	-1.1	-1.9	-1.1	-1.0	-0.9
Had menopause	0.3	0.4	2.1	-1.5	0.1	0.3	-0.4	-0.3	-0.4	-0.9	-0.5	0.3	-0.1
Had other major operations	0.2	0.2	1.4	-1.2	-0.2	-0.1	-0.2	-0.4	-0.1	0.1	0.4	-0.6	-0.1
Forced vital capacity (FVC)	0.3	1.1	7.6	2.8	-0.1	-0.5	0.6	1.4	0.5	0.5	0.3	0.2	0.4
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.4	1.3	0.8	1.1	1.2	0.5	0.6	0.5	0.4	-0.1	-0.2	0.2
Ever unenthusiastic/disinterested for a whole week	1.7	2.1	6.1	0.5	1.2	0.2	1.9	0.7	1.7	1.6	2.5	0.4	1.9
Qualifications: None of the above	0.5	1.1	2.2	-0.5	0.0	-0.9	1.4	0.4	1.4	1.0	1.2	1.1	1.5
Financial difficulties in last 2 years	0.5	0.7	2.7	-1.2	0.0	0.1	-0.5	-0.8	-0.4	-0.7	-1.6	-0.8	-0.6
Mouth/teeth dental problems	1.1	1.7	4.2	1.7	-1.3	-0.9	-1.1	2.0	-1.1	-0.9	-1.5	-0.9	-0.9
Heart attack	0.5	0.7	2.6	-0.8	-1.6	-1.6	-0.4	0.1	-0.3	-0.3	-0.6	0.2	-0.5
Allergy	0.5	1.1	2.9	-1.0	1.6	1.7	0.7	-1.2	0.7	0.3	0.6	0.8	0.7
Pain all over the body in last month	1.1	1.2	2.9	-1.7	0.8	-0.1	1.0	-1.4	0.7	1.0	1.3	0.9	1.3
Diabetes (self-reported)	0.1	0.1	0.3	-0.2	0.2	0.4	-0.5	-0.1	-0.6	-0.5	-0.5	0.1	-0.0
Hayfever/allergic rhinitis (self-reported)	0.4	0.5	1.2	0.9	-0.7	-0.4	-0.6	0.0	-0.5	-0.5	-1.1	-0.8	-0.9
Medication: Ramipril	1.4	1.8	3.4	-1.1	1.9	1.5	1.6	-1.3	1.6	0.6	1.2	0.4	1.6
Medication: Simvastatin	0.3	0.4	1.2	-0.6	0.6	0.1	1.0	-0.0	0.9	0.4	0.7	-0.2	1.1
Fluid intelligence score	0.8	1.7	7.7	2.8	-1.0	-1.0	-0.6	2.5	-0.6	0.3	-0.2	0.3	-0.6
Illnesses of siblings	1.6	2.3	10.3	3.2	1.0	1.8	-0.5	2.6	-0.5	-0.5	-0.7	0.3	-0.5
Neuroticism score	0.5	1.0	2.3	0.6	0.3	-0.4	1.2	0.9	1.2	1.4	1.5	0.0	1.1
Weight	0.7	3.6	25.6	-5.1	0.4	0.5	0.0	-2.6	0.0	-0.9	-1.0	0.8	-0.0
Impedance of arm (right)	0.8	3.6	14.7	3.8	-1.6	-0.4	-1.6	1.7	-1.5	-1.3	-1.5	-1.9	-1.8
Arm fat percentage (right)	1.6	6.2	41.6	-6.5	0.2	0.2	0.5	-4.3	0.5	-0.9	-0.7	0.3	0.4
Trunk fat-free mass	0.1	0.5	2.2	-1.5	0.2	0.1	-0.4	0.3	-0.5	-0.5	-1.0	1.0	-0.4
Hip circumference	1.2	5.4	34.0	-5.8	0.9	1.3	-0.4	-3.4	-0.3	-1.5	-1.6	-0.2	-0.5
Time employed in main current job	2.0	2.3	5.4	-0.8	2.3	2.1	1.5	-1.7	1.4	0.5	1.0	1.3	1.6
Alcohol intake versus 10 years previously	0.8	1.2	4.7	-0.6	0.7	-0.1	1.3	-0.4	1.2	1.1	0.4	2.2	1.3
Father’s age at death	0.8	1.0	1.7	-0.1	0.5	1.2	-1.2	0.4	-1.2	-1.1	-1.3	-1.1	-1.1
Worrier / anxious feelings	0.4	0.8	2.1	1.4	-0.9	-0.8	-0.4	1.4	-0.5	-0.5	-0.4	-1.1	-0.5
Frequency of tiredness / lethargy in last 2 weeks	0.7	1.1	2.2	-1.4	0.0	-0.7	1.1	-1.5	1.1	0.7	1.0	0.9	1.2
Falls in the last year	0.7	0.9	2.3	-0.3	-0.5	-0.1	-1.3	-0.6	-1.3	-0.4	-0.6	-1.5	-1.5
Hair/balding pattern: Pattern 3	1.1	1.6	3.2	-0.1	0.9	0.1	1.7	-0.2	1.8	1.8	1.3	1.3	1.6
Number of live births	0.1	0.2	0.3	-0.0	-0.4	-0.1	-0.5	-0.2	-0.5	-0.4	-0.5	-0.5	-0.5
Forced expiratory volume in 1-second (FEV1)	0.4	1.3	5.1	2.3	-0.0	-0.8	1.0	1.3	1.0	1.1	0.9	0.9	0.9
Pulse rate	0.3	0.5	1.5	-0.3	-1.2	-1.0	-0.6	-0.5	-0.6	-0.6	-0.6	0.3	-0.4
Happiness	0.8	1.0	4.6	-2.1	0.4	0.9	-0.3	-1.8	-0.1	-0.1	0.2	-0.8	-0.5
Noisy workplace	3.7	4.6	7.9	-2.6	2.1	1.4	2.3	-2.8	2.4	2.0	2.2	0.9	2.0
Qualifications: A levels/AS levels or equivalent	0.5	1.0	2.4	1.0	-0.3	0.6	-1.0	0.4	-0.9	-0.8	-1.6	-1.2	-1.3
Serious illness, injury or assault of a close relative in last 2 years	0.3	0.4	0.9	-0.5	1.0	0.8	0.5	-0.6	0.4	0.4	0.6	-0.8	0.4
Mouth/teeth dental problems: Dentures	0.2	0.3	1.8	-1.4	-0.0	-0.3	0.3	-0.5	0.3	0.4	0.2	0.4	0.3
Asthma	0.6	1.1	4.5	1.3	-1.5	-2.1	-0.1	1.6	-0.1	0.0	-0.7	0.2	-0.0
Medication: Ibuprofen (e.g. Nurofen)	2.5	3.2	4.3	-1.9	0.4	1.8	-2.1	-1.9	-2.1	-1.9	-1.7	-1.5	-2.0
Medication: Cholesterol lowering	0.5	0.8	1.6	-1.3	0.3	-0.4	0.9	-0.9	0.8	0.8	1.0	1.0	1.1
Depression (self-reported)	1.9	2.3	4.4	0.9	0.5	-0.5	2.1	1.4	2.0	1.5	1.9	1.2	2.0
Medication: Lansoprazole	0.9	1.0	2.2	-0.9	0.2	-0.5	1.5	-0.6	1.5	0.8	0.2	1.2	1.4
Prospective memory result	0.3	0.4	1.0	-0.6	0.5	0.2	0.8	-0.8	1.0	0.5	0.1	0.4	0.6
Lung cancer (father)	2.7	3.1	6.2	-0.3	0.9	-0.2	2.4	-0.3	2.5	2.1	2.4	1.4	2.5
Illnesses of mother	2.1	2.6	4.3	1.5	-1.9	-1.2	-2.0	1.9	-2.1	-1.3	-1.1	-1.2	-1.6
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	0.9	1.8	1.3	0.1	-0.8	1.2	0.4	1.3	1.2	0.9	0.4	1.0
Pulse wave Arterial Stiffness index	0.7	0.9	3.2	0.2	-0.9	-0.4	-0.8	0.7	-0.7	-0.7	-1.1	-1.8	-1.0
Impedance of arm (left)	0.9	4.4	9.4	3.1	-1.9	-0.5	-2.3	0.8	-2.1	-1.9	-2.1	-2.2	-2.6
Arm fat mass (right)	1.3	5.5	38.9	-6.2	0.4	0.2	0.4	-3.7	0.4	-0.9	-0.8	0.5	0.4
Trunk predicted mass	0.1	0.5	2.5	-1.6	0.4	0.3	-0.2	0.2	-0.3	-0.3	-0.8	1.1	-0.2
Standing height	0.4	3.9	11.8	3.4	-0.6	0.3	-1.9	3.1	-1.9	-1.2	-2.1	-0.2	-2.1
Length of working week for main job	0.5	0.5	1.4	-0.9	-0.8	-0.4	-0.7	-1.2	-0.5	-0.3	-0.8	0.4	-0.9
Exposure to tobacco smoke at home	0.2	0.2	0.8	-0.8	-0.0	-0.3	0.1	-0.9	-0.0	-0.2	0.6	0.4	0.5
Breastfed as a baby	1.2	1.4	3.6	-0.3	-0.3	0.5	-1.5	0.1	-1.6	-1.9	-0.8	-1.7	-1.3
Tense / ‘highly strung’	0.2	0.4	1.3	-1.1	0.3	-0.3	0.6	-0.1	0.6	0.8	0.8	0.5	0.7
Seen doctor (GP) for nerves, anxiety, tension or depression	0.1	0.2	0.5	-0.3	-0.1	0.1	-0.4	0.7	-0.5	-0.5	-0.1	-0.6	-0.4
Hair/balding pattern: Pattern 4	0.1	0.3	2.1	-1.5	-0.0	-0.1	-0.1	-0.7	-0.1	-0.3	0.3	-0.7	-0.0
Birth weight of first child	0.3	0.6	2.2	-0.1	1.1	1.5	-0.6	-0.8	-0.7	-0.8	-0.2	-0.6	-0.6
Peak expiratory flow (PEF)	0.6	1.3	5.0	1.2	0.2	-0.4	0.8	1.6	0.8	1.2	0.7	2.2	1.0
Pulse wave reflection index	0.2	0.3	2.0	-0.5	-0.1	-0.1	0.1	0.3	0.3	0.5	0.1	-1.4	-0.4
Ever highly irritable/argumentative for 2 days	0.5	0.6	1.2	0.1	0.2	-0.5	0.7	1.0	0.7	1.1	0.7	1.1	0.8
Loud music exposure frequency	1.6	1.8	4.5	-1.8	2.1	1.9	1.0	-1.0	1.0	0.3	1.2	0.7	1.1
Qualifications: O levels/GCSEs or equivalent	0.3	0.5	0.8	0.9	0.7	0.5	0.9	0.0	0.9	0.7	0.5	0.8	0.8
Mouth/teeth dental problems: Bleeding gums	1.1	1.4	7.5	-2.1	0.7	1.1	-0.2	-2.7	-0.2	-0.3	0.1	0.1	-0.2
Blood clot in the leg (DVT)	0.5	0.7	1.4	0.3	-0.0	0.8	-1.2	0.1	-1.2	-0.7	-0.5	-1.0	-1.1
Medication: Paracetamol	0.7	1.1	2.5	-1.6	-0.6	0.0	-1.2	-1.5	-1.1	-0.9	-0.9	0.1	-1.3
Headache pain in last month	2.2	3.8	6.7	-1.5	2.6	2.0	2.1	-1.1	2.2	2.1	2.3	1.2	1.9
Medication for cholesterol, blood pressure or diabetes	0.4	0.6	1.3	1.1	-0.2	0.5	-0.8	0.9	-0.6	-0.5	-0.6	-1.1	-1.0
Glaucoma (self-reported)	0.9	1.0	4.1	2.0	-0.5	-1.2	0.6	1.0	0.6	1.2	0.8	0.6	0.6
Gout (self-reported)	0.6	0.8	4.2	-0.2	1.4	2.0	0.1	-0.3	0.3	-0.5	-0.4	-1.2	-0.2
Hypothyroidism/myxoedema (self-reported)	0.7	1.3	3.3	0.9	1.8	1.8	1.1	0.4	1.1	0.4	1.3	0.4	1.2
Medication: Amlodipine	0.9	1.3	3.4	-1.8	-0.9	-1.7	0.5	-1.2	0.5	0.9	0.3	1.5	0.6
Medication: Ventolin 100micrograms inhaler	0.5	0.6	1.1	0.6	0.9	0.5	0.9	0.3	0.8	0.8	0.3	1.0	1.1
Birth weight	0.2	0.4	1.4	0.2	-1.1	-1.2	-0.3	0.9	-0.3	0.3	-0.0	0.3	-0.2
Chronic bronchitis/emphysema (mother)	0.6	0.7	1.8	-1.0	-0.4	-0.8	0.6	-1.3	0.6	0.5	0.9	0.9	0.7
High blood pressure (siblings)	1.2	1.7	11.2	-3.4	-0.5	-0.8	-0.0	-2.2	-0.0	-0.1	0.2	-0.7	0.1
Forced vital capacity (FVC), Best measure	0.2	0.6	2.6	1.6	0.5	-0.1	0.9	0.4	0.9	0.8	0.4	0.2	0.7
Body fat percentage	1.6	6.3	39.6	-6.3	0.3	0.7	-0.0	-4.5	0.1	-1.2	-1.0	0.2	-0.1
Leg fat percentage (right)	1.8	6.5	41.0	-6.4	0.5	0.3	0.7	-4.5	0.8	-0.4	-0.1	1.2	0.7
Arm fat-free mass (right)	0.2	1.1	8.2	-2.9	0.6	0.4	-0.1	-0.7	-0.1	-0.4	-0.6	1.1	-0.1
Exposure to tobacco smoke outside home	1.1	1.4	3.8	-0.9	1.0	0.1	1.4	-1.1	1.3	1.2	2.0	0.5	1.5
Comparative body size at age 10	0.4	1.0	2.0	-0.9	-0.1	0.5	-1.3	-0.1	-1.3	-1.4	-1.2	-1.2	-1.0
Number of full brothers	0.9	1.2	3.8	1.7	0.5	0.2	0.7	2.0	0.8	1.2	1.1	-0.6	0.5
Worry too long after embarrassment	0.8	1.4	2.9	0.1	0.9	0.2	1.6	0.0	1.5	1.1	1.7	1.1	1.7
Seen a psychiatrist for nerves, anxiety, tension or depression	0.6	0.8	1.9	0.8	0.3	-0.4	1.2	0.9	1.1	0.8	1.0	0.8	1.4
Wheeze or whistling in the chest in last year	0.2	0.4	1.5	-1.2	-0.2	-0.5	0.1	-1.2	0.1	-0.0	-0.3	-0.5	-0.1
Number of children fathered	0.2	0.3	1.2	-1.1	0.4	0.2	0.1	-0.7	0.2	0.4	0.3	0.5	0.4
Reason for reducing amount of alcohol drunk: Health precaution	0.3	0.4	0.7	-0.4	0.3	0.8	-0.7	-0.8	-0.7	-0.6	-0.5	-0.2	-0.5
Age at first live birth	0.6	1.1	1.9	0.6	-0.2	0.7	-1.3	-0.5	-1.4	-1.4	-1.3	-0.9	-1.3
Pulse wave peak to peak time	0.6	0.7	2.7	0.2	0.9	0.5	0.7	-0.5	0.5	0.6	0.9	1.6	0.9
Health satisfaction	1.4	1.8	7.3	-2.7	0.5	-0.2	1.2	-2.0	1.2	1.4	0.9	0.1	0.9
Shortness of breath walking on level ground	1.4	1.6	3.5	-1.4	-0.4	-1.6	1.9	-0.5	1.9	1.3	0.8	0.3	1.5
Qualifications: College or University degree	0.8	2.5	5.7	2.4	-0.3	1.0	-1.9	1.6	-1.8	-1.1	-1.3	-1.3	-1.9
Eye problems/disorders: None of the above	1.4	1.6	3.4	1.3	-1.6	-0.8	-1.2	1.8	-1.2	-1.0	-1.4	-0.3	-1.0
Mouth/teeth dental problems: Loose teeth	1.4	1.7	3.0	-0.3	1.6	1.0	1.5	-0.6	1.5	1.5	1.7	1.0	1.3
Emphysema/chronic bronchitis	0.4	0.4	0.9	0.6	-0.9	-0.7	-0.6	-0.0	-0.5	-0.1	-0.8	-0.6	-0.9
Medication for pain relief, constipation, heartburn	0.9	1.5	6.5	2.5	-0.5	-1.0	0.7	2.1	0.8	1.0	0.7	-0.2	0.5
Neck or shoulder pain in last month	0.8	1.2	4.9	-2.2	0.9	1.0	0.1	-2.1	0.0	-0.2	0.6	-0.5	0.1
Medication: Blood pressure	0.3	0.6	0.9	-0.9	0.7	0.2	0.9	-0.8	0.8	0.4	0.7	0.7	1.0
Angina (self-reported)	0.8	1.0	2.1	-0.5	0.7	0.0	1.3	-0.2	1.3	1.5	1.3	0.8	1.2
Migraine (self-reported)	0.5	0.6	2.9	-1.1	1.2	1.7	0.0	-0.4	0.1	0.2	0.3	-0.3	0.0
Medication: Ibuprofen	3.2	3.9	5.8	-2.2	0.4	1.8	-2.4	-2.0	-2.4	-2.0	-1.6	-1.8	-2.2
Medication: Allopurinol	0.5	0.7	1.9	-0.5	0.7	1.4	-0.6	0.0	-0.6	-0.9	-0.7	-1.3	-0.7
Medication: Omeprazole	0.7	0.9	2.0	-1.1	0.3	1.0	-0.9	-1.4	-0.9	-1.1	-0.9	-0.1	-0.7
Medication: Seretide 50 evohaler	0.6	0.7	1.8	-0.1	0.6	-0.1	1.2	-0.4	1.2	1.4	0.8	0.5	1.1
Mean time to correctly identify matches	1.2	2.4	6.8	-2.6	-0.9	-0.5	-1.0	-2.6	-0.9	-1.4	-1.4	-1.4	-1.2
Heart disease (mother)	3.3	4.0	10.3	-0.6	3.2	2.8	2.2	-1.1	2.3	1.7	1.6	1.0	1.9
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.9	1.0	2.2	0.9	-0.2	-0.8	0.9	1.3	1.0	1.4	1.5	0.7	0.7
Whole body fat mass	1.4	5.8	37.9	-6.2	0.4	0.6	0.0	-4.0	0.1	-1.2	-1.1	0.5	-0.1
Leg fat mass (right)	1.8	6.8	43.8	-6.6	1.0	0.8	0.6	-4.5	0.7	-0.6	-0.4	1.2	0.6
Arm predicted mass (right)	0.2	1.2	8.9	-3.0	0.6	0.3	0.1	-0.9	-0.0	-0.2	-0.4	1.2	0.1
Pulse rate, automated reading	0.1	0.4	1.5	-1.2	0.5	0.5	0.2	-1.2	0.1	-0.4	-0.2	0.8	0.5
Alcohol intake frequency.	1.2	2.7	16.7	-4.1	-0.3	-1.2	0.7	-2.0	0.6	0.6	0.8	1.4	1.1
Comparative height size at age 10	0.3	1.7	4.9	0.1	0.0	1.0	-1.7	-0.5	-1.7	-1.5	-2.2	0.4	-1.7
Number of full sisters	1.7	2.1	4.4	-0.9	0.9	-0.2	1.8	-0.8	1.6	1.2	1.7	2.0	2.1
Suffer from ‘nerves’	0.6	0.9	5.2	2.3	-0.2	-0.5	0.2	1.6	0.1	0.2	0.7	-0.1	0.5
Overall health rating	3.3	7.0	31.8	-5.6	2.0	1.2	1.6	-4.9	1.5	0.5	0.9	1.0	1.7
Chest pain or discomfort	0.8	1.1	2.2	-1.4	1.0	0.2	1.2	-1.5	1.2	1.1	1.1	0.3	1.0
Had major operations	0.4	0.5	1.6	-0.5	-0.9	-0.8	-0.7	-0.0	-0.6	-0.5	-1.3	0.2	-0.7
Age at last live birth	0.7	1.0	2.5	0.2	0.0	0.9	-1.2	-0.7	-1.3	-1.6	-1.1	-0.9	-1.1
Family relationship satisfaction	0.9	1.1	5.4	-2.3	0.3	0.2	0.4	-1.9	0.5	0.9	0.6	-0.2	0.1
Leg pain on walking	0.5	0.6	1.9	-1.4	-0.2	0.3	-0.6	-1.0	-0.5	-0.7	-0.8	-1.0	-0.7
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.4	0.9	-0.9	-0.9	-0.7	-0.5	-0.8	-0.6	-0.7	0.1	-0.2	-0.4
Commuting to job workplace: Car/motor vehicle	0.3	0.3	0.8	-0.5	0.2	-0.3	0.9	-0.5	0.8	-0.1	0.4	0.1	0.8
Illness, injury, bereavement, stress in last 2 years	0.0	0.1	0.4	0.6	-0.0	0.2	-0.1	0.3	-0.0	-0.0	-0.2	-0.0	-0.1
Medication: Aspirin	1.2	1.5	8.5	-2.9	0.9	0.6	0.4	-2.1	0.3	0.4	0.5	0.4	0.6
Supplements: Vitamin C	0.5	0.6	1.8	1.3	0.1	0.5	-0.6	0.4	-0.5	-0.2	-0.2	-1.3	-0.9
Knee pain experienced in last month	0.7	1.0	4.8	-2.2	-0.2	-0.7	0.1	-1.1	0.2	1.1	0.8	1.3	0.3
Hypertension (Self-reported)	0.5	1.5	7.3	-2.7	1.0	0.9	0.3	-2.2	0.1	-0.8	0.1	-0.4	0.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.1	1.2	2.7	-0.7	0.6	-0.2	1.3	-1.5	1.2	0.6	1.6	0.5	1.6
Illnesses of father: Heart disease	1.2	1.7	3.9	-1.4	2.0	1.7	1.4	-1.2	1.3	0.3	1.3	-0.7	1.1
Illnesses of siblings: Diabetes	0.8	1.0	2.0	-1.4	-0.4	-1.2	1.0	-1.1	1.1	0.9	1.0	-0.0	0.8
Smoking status: Previous	0.3	0.4	2.7	-1.6	0.4	0.5	-0.0	-1.0	-0.0	0.1	0.2	0.1	0.2
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.4	1.0	0.9	0.8	0.6	0.4	1.0	0.3	0.3	0.1	0.3	0.5
Whole body fat-free mass	0.2	0.9	5.8	-2.4	0.3	0.3	-0.3	-0.4	-0.4	-0.6	-1.1	0.8	-0.4
Leg fat-free mass (right)	0.2	1.2	8.0	-2.8	0.4	0.5	-0.3	-1.0	-0.4	-0.9	-1.2	0.5	-0.5
Arm fat percentage (left)	1.8	7.2	47.4	-6.9	0.1	0.3	0.1	-4.7	0.2	-1.2	-1.0	0.2	0.0
Average weekly red wine intake	0.4	0.6	1.3	1.0	-0.5	-1.0	0.6	0.8	0.5	0.7	1.1	-0.2	0.6
Handedness (chirality/laterality): Left-handed	0.1	0.1	0.6	-0.8	-0.1	0.0	-0.3	-0.3	-0.3	-0.4	0.1	-0.2	-0.2
Mood swings	0.2	0.3	0.9	-0.6	0.7	0.4	0.8	-0.0	0.9	0.6	0.4	0.1	0.5
Loneliness, isolation	0.4	0.5	1.0	-0.3	1.0	0.8	0.9	-0.4	1.0	0.8	0.6	0.1	0.6
Long-standing illness, disability or infirmity	0.7	1.0	3.1	-1.5	-0.4	-0.0	-1.0	-1.7	-0.9	-1.0	-1.1	-0.0	-0.9
Ever had bowel cancer screening	0.2	0.2	1.0	0.4	-0.3	-0.6	0.3	1.0	0.1	-0.3	0.2	0.1	0.5
Diabetes diagnosed by doctor	0.1	0.2	0.3	-0.5	-0.1	-0.0	-0.4	-0.5	-0.5	-0.5	-0.5	0.2	-0.0
Ever had stillbirth, spontaneous miscarriage or termination	0.5	0.6	2.6	-0.4	0.7	1.2	-0.2	-0.5	-0.1	-0.7	-0.5	-1.6	-0.3
Friendships satisfaction	1.0	1.2	3.1	-0.1	0.8	0.3	1.2	-0.5	1.4	1.8	1.7	0.6	1.1
Qualifications: nursing, teaching	0.3	0.4	1.2	-0.3	-0.3	0.1	-0.7	-0.7	-0.6	-0.3	-1.1	-0.0	-1.0
Commuting to job workplace: Walk	0.5	0.5	2.2	0.4	1.3	1.5	0.1	0.6	0.2	0.2	0.2	-1.0	0.0
Eye problems/disorders: Cataract	0.7	0.8	3.8	-1.9	0.8	0.5	0.5	-1.4	0.4	0.6	0.6	-0.5	0.4
Mouth/teeth dental problems: Mouth ulcers	1.5	2.4	8.2	-1.0	2.9	2.8	1.1	-1.1	1.1	1.0	0.9	0.6	0.9
Medication for cholesterol	0.9	1.3	6.3	2.5	-0.7	-1.0	-0.1	1.9	-0.0	1.1	0.3	0.8	-0.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.1	0.2	0.6	0.3	0.5	0.8	-0.1	0.5	-0.1	-0.1	-0.4	-0.4	-0.3
Back pain experienced in last month	2.0	3.0	10.4	-3.2	1.2	0.8	1.1	-3.2	1.2	0.5	0.8	1.4	1.2
Mineral and other dietary supplements	0.3	0.4	1.1	-1.1	0.9	0.9	0.4	-0.4	0.5	0.3	-0.2	1.0	0.4
Breast cancer (self-reported)	0.1	0.2	0.8	-0.2	-0.2	-0.1	-0.3	0.1	-0.3	-0.6	-0.1	0.9	0.1
Asthma (self-reported)	0.6	1.2	4.4	1.5	-1.5	-2.1	-0.1	1.6	-0.1	0.1	-0.6	0.3	-0.0
Osteoporosis (self-reported)	0.1	0.2	0.7	0.5	-0.1	-0.4	0.2	0.8	0.2	0.2	0.1	-0.5	0.4
Osteoarthritis (self-reported)	0.4	0.5	2.1	-1.4	-0.1	0.3	-0.6	-1.1	-0.4	-0.4	-0.7	-0.6	-0.8
Medication: Aspirin	1.9	2.5	11.2	-3.4	1.2	0.6	1.0	-2.3	0.8	0.8	1.3	0.9	1.4
Medication: Gliclazide	1.1	1.2	3.6	-1.9	-1.0	-1.3	-0.2	-1.6	-0.3	-0.3	-1.3	1.3	0.1
Illnesses of father: None of the above (group 1)	1.2	1.4	4.7	0.8	-2.2	-2.1	-0.9	1.0	-0.9	-0.2	-0.8	0.9	-0.7
Smoking status: Current	0.4	0.6	1.5	-1.2	-0.2	0.0	-0.7	-0.5	-0.7	-0.9	-0.9	-1.2	-0.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.6	3.4	7.0	-0.2	0.7	-0.7	2.3	-0.6	2.2	2.0	2.3	2.5	2.6
Whole body water mass	0.1	0.8	5.7	-2.4	0.3	0.2	-0.3	-0.4	-0.3	-0.5	-1.0	0.9	-0.3
Leg predicted mass (right)	0.2	1.2	8.0	-2.8	0.4	0.5	-0.3	-1.0	-0.4	-0.8	-1.2	0.6	-0.4
Arm fat mass (left)	1.4	5.9	41.9	-6.5	0.3	0.3	0.3	-3.9	0.3	-0.9	-0.9	0.5	0.2
Number of self-reported non-cancer illnesses	0.5	0.9	3.2	-1.8	0.4	0.6	-0.3	-1.6	-0.4	-1.3	-0.7	-0.7	-0.2
Average weekly champagne plus white wine intake	0.3	0.4	0.9	-0.1	-0.9	-0.7	-0.8	0.2	-0.7	-0.1	-0.8	-0.4	-0.8
Miserableness	0.5	0.8	2.0	0.9	0.6	0.1	0.9	1.3	0.9	1.4	1.2	0.4	0.6
Guilty feelings	0.4	0.6	1.1	-1.1	1.0	0.8	0.7	-0.7	0.8	0.6	1.0	0.3	0.7
Wears glasses or contact lenses	0.1	0.2	0.7	-0.6	-0.2	-0.3	0.1	0.1	0.2	0.4	0.2	0.8	0.3
Ever taken oral contraceptive pill	0.3	0.3	0.8	0.1	-0.9	-0.9	-0.1	0.9	-0.0	0.3	-0.4	0.5	-0.1
Hearing aid user	1.1	1.3	3.2	0.6	1.8	1.7	1.1	0.7	1.1	0.7	0.7	-0.9	1.1
Mother’s age at death	0.1	0.1	0.6	0.4	-0.5	-0.8	0.2	0.4	0.1	0.0	0.4	0.3	0.1
Financial situation satisfaction	1.0	1.2	2.9	-1.7	0.9	0.2	1.1	-0.9	1.2	1.6	1.1	0.4	0.8
Tinnitus: Yes, now most or all of the time	0.1	0.1	0.8	-0.9	0.3	0.3	0.3	-0.1	0.3	0.2	-0.2	-0.4	-0.0
Commuting to job workplace: Public transport	0.2	0.2	1.0	1.0	0.3	0.6	-0.2	0.3	-0.1	-0.1	0.5	-0.0	-0.0
Eye problems/disorders: Glaucoma	0.4	0.4	1.3	1.0	0.3	-0.3	0.6	-0.3	0.6	1.1	0.6	0.8	0.4
Medication: Blood pressure	0.7	1.4	6.2	-2.5	-0.6	-0.5	-0.4	-1.9	-0.5	-1.6	-0.6	-0.4	-0.1
Pain type(s) experienced in last month: Hip pain	2.2	2.8	17.0	-4.1	0.7	0.8	-0.1	-3.1	-0.0	-0.1	-0.1	-0.7	-0.2
Supplements: Fish oil (including cod liver oil)	0.4	0.5	1.1	-0.4	0.1	0.5	-0.8	-1.1	-0.8	-0.8	-0.6	-1.0	-0.8
High cholesterol (Self-reported)	0.8	1.4	2.8	-1.1	1.6	1.0	1.4	-1.0	1.2	0.5	1.2	0.2	1.7
Medication: Bendroflumethiazide	0.3	0.4	2.0	-1.2	-0.1	-0.1	-0.0	-1.4	-0.1	-0.7	-0.4	0.3	-0.0
Medication: Paracetamol	1.1	1.7	2.7	-1.6	-0.7	0.1	-1.6	-1.5	-1.5	-1.4	-1.3	-0.3	-1.6
Medication: Lisinopril	0.3	0.4	1.4	-1.2	-0.9	-0.9	-0.3	-0.5	-0.4	-0.6	-0.1	-0.3	-0.3
Medication: Atorvastatin	0.4	0.5	2.5	-1.2	0.5	0.6	0.1	-1.6	0.1	-0.5	-0.2	-0.1	0.1
Illnesses of father: High blood pressure	2.0	2.4	4.8	-0.4	2.2	1.9	1.8	-0.3	1.9	1.8	1.9	0.2	1.3
Alcohol drinker status: Never	1.0	1.1	5.7	-1.1	-1.7	-2.4	-0.1	0.6	-0.0	0.9	-0.4	0.6	-0.2
Ever smoked	0.9	1.7	2.6	-1.4	0.1	1.1	-1.6	-0.7	-1.5	-1.4	-1.2	-1.6	-1.4
Basal metabolic rate	0.2	1.3	9.4	-3.1	0.4	0.4	-0.2	-1.0	-0.2	-0.6	-1.0	0.9	-0.3
Leg fat percentage (left)	1.6	5.8	36.7	-6.1	0.6	0.4	0.7	-4.2	0.7	-0.3	-0.0	1.2	0.7
Arm fat-free mass (left)	0.2	1.1	8.4	-2.9	0.6	0.3	0.3	-0.5	0.3	-0.1	-0.5	1.3	0.3
Number of operations (self-reported)	0.7	1.1	2.3	-0.6	-1.5	-1.1	-1.3	-0.1	-1.1	-0.8	-1.3	-0.4	-1.3
Average weekly beer plus cider intake	0.3	0.4	1.5	-1.2	0.3	0.2	0.4	-1.2	0.4	-0.0	0.7	0.2	0.3
Irritability	1.4	2.3	4.2	0.4	0.5	-0.8	2.1	1.3	2.0	1.9	1.6	1.6	1.9
Risk taking	1.0	1.4	6.5	-2.5	0.4	0.7	-0.7	-2.1	-0.9	-0.8	-0.6	-0.3	-0.4
Ever had prostate specific antigen (PSA) test	0.2	0.2	0.6	0.2	0.4	0.0	0.6	0.0	0.5	-0.1	0.8	0.4	0.8
Fractured/broken bones in last 5 years	0.2	0.2	0.5	-0.4	0.3	0.3	-0.5	0.2	-0.7	-0.7	-0.5	-0.4	-0.1
Age started oral contraceptive pill	2.1	2.6	4.9	0.0	-1.7	-0.7	-2.2	0.4	-2.2	-2.1	-2.2	-0.3	-2.0
Diastolic blood pressure, automated reading	0.3	1.1	2.1	-1.0	1.3	0.7	1.4	-0.6	1.4	0.7	0.9	0.6	1.2
Ever depressed for a whole week	0.2	0.2	0.6	-0.6	0.8	0.6	0.4	-0.2	0.3	0.1	0.7	-0.1	0.4
Unable to work because of sickness or disability	1.2	1.5	3.0	-1.2	-0.3	-1.6	1.4	-0.5	1.3	1.7	0.9	1.1	1.4
Commuting to job workplace: Cycle	1.4	1.6	3.2	1.2	-0.6	0.4	-1.8	1.0	-1.8	-1.2	-1.3	-0.9	-1.8
Myopia	2.2	3.2	8.4	2.7	-2.1	-2.9	-0.2	2.7	-0.3	0.4	-0.3	1.9	0.1
Vascular/heart problems diagnosed by doctor	0.4	1.1	6.7	2.6	-0.0	0.5	-0.5	1.7	-0.4	0.1	-0.6	0.1	-0.5
Cholesterol lowering medication	0.2	0.3	0.7	-0.6	0.7	0.6	0.5	-0.9	0.5	-0.6	-0.4	-0.1	0.6
Medication: Omeprazole (e.g. Zanprol)	0.1	0.1	0.4	-0.1	-0.2	-0.2	-0.1	-0.6	-0.1	-0.5	-0.3	0.6	0.2
Pain experienced in last month	3.4	5.7	14.4	3.8	-2.1	-1.4	-1.8	3.6	-1.9	-1.7	-2.1	-2.4	-1.7
Supplements: Calcium	0.1	0.1	0.2	0.2	0.0	-0.2	0.4	0.1	0.4	0.1	0.2	0.0	0.5
Basal cell carcinoma (self-reported)	4.9	5.8	10.1	-0.1	-0.1	-2.2	3.1	0.3	3.2	2.8	2.5	3.1	3.1
Heart attack/myocardial infarction (self-reported)	0.5	0.7	2.4	-0.8	-1.6	-1.5	-0.5	0.1	-0.4	-0.4	-0.8	0.1	-0.6
Deep venous thrombosis (DVT) (self-reported)	0.4	0.5	1.0	0.3	0.2	0.9	-1.0	-0.1	-1.0	-0.6	-0.4	-0.8	-1.0
Heart disease (siblings)	0.7	0.9	1.8	-1.0	-0.6	-1.3	0.8	-1.4	0.8	0.7	0.8	1.0	0.7
Alcohol drinker status: Previous	0.9	1.1	5.2	-2.3	0.2	0.1	-0.3	-2.2	-0.4	-0.2	0.5	0.0	0.0
Pack years of smoking	1.1	1.6	7.1	-2.5	0.7	1.0	-0.3	-2.7	-0.3	-0.9	-0.5	0.2	-0.2
Impedance of whole body	0.6	3.1	13.8	3.7	-1.3	-0.2	-1.7	1.2	-1.5	-1.0	-1.2	-1.7	-1.9
Leg fat mass (left)	1.7	6.5	42.0	-6.5	0.9	0.8	0.6	-4.3	0.6	-0.7	-0.4	1.0	0.6
Arm predicted mass (left)	0.3	1.4	9.3	-3.1	0.8	0.4	0.4	-0.9	0.4	0.0	-0.2	1.5	0.5