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chr11:64,501,991-66,919,278

Best TWAS P=1.42e-10 · Best GWAS P=3.79e-13 conditioned to 0.0164

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	FIBP	0.08	0.11	enet	20	0.12	8.1e-14	4.9	6.4	1.4e-10	-0.34	1.00	0.00	TRUE
9	GTEx	Esophagus Muscularis	CTD-3074O7.5	0.22	0.02	enet	17	0.09	3.7e-06	-3.0	6.4	1.5e-10	-0.50	0.26	0.52	TRUE
26	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	SNX32	0.30	0.19	lasso	1	0.14	3.9e-06	5.9	5.9	4.1e-09	-0.12	0.00	1.00	FALSE
27	The Cancer Genome Atlas	Stomach Adenocarcinoma	SNX32	0.12	0.13	blup	60	0.13	1.2e-09	4.9	5.8	6.8e-09	-0.16	0.04	0.95	FALSE
21	The Cancer Genome Atlas	Brain Lower Grade Glioma	FIBP	0.04	0.04	lasso	3	0.04	1.2e-05	5.9	5.8	7.4e-09	-0.13	0.00	1.00	FALSE
2	CommonMind	Brain Pre-frontal Cortex	SNX32	0.46	0.36	lasso	8	0.39	1.9e-50	5.9	5.8	8.2e-09	-0.16	0.96	0.04	FALSE
28	The Cancer Genome Atlas	Thyroid Carcinoma	SNX32	0.23	0.26	lasso	7	0.25	6.4e-24	5.9	5.6	1.7e-08	-0.14	0.00	1.00	FALSE
23	The Cancer Genome Atlas	Lung Adenocarcinoma	SNX32	0.14	0.09	blup	60	0.13	8.8e-15	5.9	5.6	2.2e-08	-0.16	0.01	0.99	FALSE
14	ROSMAP	Brain Pre-frontal Cortex	SNX32	0.50	0.53	lasso	13	0.54	1.1e-81	5.9	5.5	3.5e-08	-0.13	0.95	0.05	FALSE
6	GTEx	Breast Mammary Tissue (Male)	NEAT1	0.27	0.01	enet	29	0.03	6.3e-02	4.1	5.5	3.6e-08	-0.16	0.04	0.27	FALSE
13	GTEx	Thyroid	PACS1	0.09	0.04	enet	16	0.09	2.8e-07	-7.2	-5.5	4.0e-08	0.79	0.01	0.99	FALSE
3	GTEx	Adrenal Gland	CTSW	0.13	0.08	lasso	12	0.06	3.0e-03	4.6	-5.5	4.8e-08	0.22	0.31	0.17	FALSE
16	The Cancer Genome Atlas	Breast Invasive Carcinoma	SNX32	0.15	0.17	blup	60	0.17	2.9e-34	5.9	5.5	5.2e-08	-0.16	0.00	1.00	FALSE
18	The Cancer Genome Atlas	Glioblastoma Multiforme	CTSW	0.16	0.18	enet	16	0.19	2.3e-06	4.6	-5.4	5.3e-08	0.23	0.08	0.83	FALSE
10	GTEx	Heart Atrial Appendage	RP11-867G23.1	0.19	0.13	lasso	5	0.11	1.6e-05	-5.3	-5.4	6.7e-08	0.66	0.09	0.85	FALSE
7	GTEx	Cells EBV-transformed lymphocytes	FIBP	0.40	0.21	enet	26	0.29	4.3e-10	4.9	5.3	8.8e-08	-0.17	0.99	0.00	FALSE
17	The Cancer Genome Atlas	Colon Adenocarcinoma	SNX32	0.11	0.08	enet	5	0.07	9.7e-05	5.0	5.3	1.1e-07	-0.14	0.00	1.00	FALSE
29	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	CTSW	0.24	0.21	enet	21	0.24	2.9e-07	4.9	-5.3	1.3e-07	0.17	0.06	0.93	FALSE
24	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	SNX32	0.22	0.21	enet	16	0.24	6.2e-27	5.9	5.3	1.4e-07	-0.17	0.00	1.00	FALSE
11	GTEx	Muscle Skeletal	FIBP	0.12	0.13	enet	10	0.13	2.6e-12	4.9	5.2	1.7e-07	-0.17	1.00	0.00	FALSE
25	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	SNX32	0.08	0.10	blup	60	0.11	6.0e-08	5.9	5.2	1.7e-07	-0.19	0.01	0.99	FALSE
15	The Cancer Genome Atlas	Breast Invasive Carcinoma	CTSW	0.25	0.39	blup	44	0.41	7.3e-91	4.9	-5.2	1.8e-07	0.17	0.17	0.83	FALSE
4	GTEx	Breast Mammary Tissue	CTSW	0.25	0.19	lasso	8	0.16	1.3e-08	4.9	-5.2	2.0e-07	0.13	1.00	0.00	FALSE
22	The Cancer Genome Atlas	Lung Adenocarcinoma	FIBP	0.02	0.01	blup	45	0.02	1.3e-03	5.1	5.2	2.1e-07	-0.25	0.06	0.50	FALSE
5	GTEx	Breast Mammary Tissue (Male)	LTBP3	0.11	-0.01	enet	26	-0.01	5.8e-01	4.4	5.2	2.4e-07	-0.08	0.03	0.25	FALSE
20	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	CTSW	0.32	0.26	lasso	1	0.26	4.3e-15	5.1	-5.1	2.7e-07	0.12	0.13	0.86	FALSE
19	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	SNX32	0.15	0.14	enet	8	0.15	2.5e-16	3.9	5.1	2.8e-07	-0.16	0.00	0.99	FALSE
8	GTEx	Colon Transverse	CTSW	0.37	0.27	lasso	8	0.26	1.5e-12	4.8	-5.1	3.1e-07	0.17	1.00	0.00	FALSE
12	GTEx	Skin Sun Exposed Lower leg	RP11-867G23.1	0.06	0.06	enet	7	0.02	1.3e-02	5.0	-5.1	3.1e-07	0.69	0.28	0.43	FALSE