TWAS hub - LTBP3

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.1210	0.0430	6.5e-05	0.094	NA	0.058	NA	0.074	4.4e-08	NA	1.6e-05	NA	1.1e-06
2	GTEx	Breast Mammary Tissue	0.0820	0.0400	7.0e-03	0.012	NA	0.013	NA	0.015	7.6e-02	NA	6.6e-02	NA	5.3e-02
3	GTEx	Breast Mammary Tissue (Male)	0.1144	0.0831	8.5e-02	-0.012	NA	-0.009	NA	-0.010	7.7e-01	NA	5.8e-01	NA	6.4e-01
4	GTEx	Breast Mammary Tissue (Female)	0.1088	0.0596	2.6e-02	0.106	NA	0.029	NA	0.021	4.7e-04	NA	4.7e-02	NA	7.7e-02
5	GTEx	Esophagus Muscularis	0.0960	0.0450	6.4e-03	0.004	NA	0.002	NA	0.002	1.7e-01	NA	2.3e-01	NA	2.2e-01
6	GTEx	Muscle Skeletal	0.0872	0.0353	5.4e-04	0.022	NA	0.020	NA	0.024	2.6e-03	NA	3.9e-03	NA	1.9e-03
7	GTEx	Nerve Tibial	0.1233	0.0471	1.9e-04	0.051	NA	0.081	NA	0.086	1.6e-04	NA	2.3e-06	NA	1.2e-06
8	METSIM	Adipose	0.0309	0.0159	2.0e-02	-0.002	0.007	0.002	0.009	0.001	7.5e-01	2.3e-02	1.6e-01	0.015	2.0e-01
9	TCGA	Colon Adenocarcinoma	0.0710	0.0460	8.4e-03	0.041	0.014	0.014	NA	0.020	1.9e-03	4.9e-02	5.2e-02	NA	2.3e-02
10	TCGA	Prostate Adenocarcinoma	0.1130	0.0503	2.2e-06	0.015	0.070	0.074	NA	0.063	8.6e-03	8.5e-08	3.6e-08	NA	3.3e-07

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10
Medication: Metformin	9.6	13.5	20.2	4.0	4.3	3.3	4.4	4.1	4.5	4.1	2.2	-2.4	-2.2
Type 2 Diabetes (T2D) (2018)	9.4	17.6	30.2	4.7	5.1	3.2	4.1	4.2	5.1	5.5	3.2	-3.6	-1.7
Diabetes diagnosed by doctor	8.2	13.4	22.3	4.3	4.4	2.5	4.3	4.0	4.7	4.2	2.5	-2.2	-2.1
Blood Platelet Count	8.0	93.2	151.3	-10.4	-10.7	-7.8	-10.5	-8.5	-12.3	-11.4	-9.2	10.0	0.6
Birth weight	7.2	15.6	29.9	3.9	4.9	5.5	3.8	3.6	3.1	4.4	4.0	-3.3	-1.8
Diabetes (self-reported)	7.1	10.9	17.9	3.9	4.1	1.9	4.0	3.8	4.2	3.7	2.2	-1.9	-1.8
Family relationship satisfaction	6.8	8.4	17.6	3.9	3.6	2.1	3.4	3.1	4.2	2.2	2.4	-0.9	-0.6
Shortness of breath walking on level ground	5.5	6.6	10.1	2.9	3.2	3.0	2.9	3.0	3.1	2.0	1.0	-0.6	-2.3
Blood Eosinophil Count	5.4	41.6	132.2	-5.0	-6.3	-11.5	-5.8	-5.9	-6.1	-6.9	-2.9	7.3	1.8
Mouth/teeth dental problems	5.4	8.2	16.5	-2.5	-2.8	-1.8	-2.8	-1.4	-2.6	-4.1	-2.6	4.0	3.0
Impedance of arm (left)	5.4	24.9	49.6	-4.9	-5.7	-7.0	-4.5	-3.2	-5.2	-6.3	-2.6	5.3	3.2
Eye problems/disorders: Glaucoma	5.2	6.2	11.2	-2.4	-2.9	-3.2	-1.4	-1.4	-2.7	-3.3	-0.8	3.3	1.9
Impedance of arm (right)	5.1	23.8	46.6	-4.5	-5.3	-6.8	-4.4	-3.1	-4.9	-6.4	-2.6	5.9	3.1
Health satisfaction	4.9	6.4	12.3	2.5	2.9	3.5	2.2	3.1	2.6	2.5	2.6	-1.8	0.1
Type 2 Diabetes (T2D) (2012)	4.7	5.4	13.8	2.8	2.8	2.0	2.4	2.3	2.6	3.7	1.6	0.0	0.0
Diabetes (mother)	4.7	5.9	12.4	2.6	3.0	2.1	2.1	1.7	2.6	3.5	1.3	-2.4	-2.2
Age when periods started (menarche)	4.7	11.4	21.5	-3.2	-3.6	-2.3	-3.6	-2.0	-3.3	-4.6	-3.0	4.4	2.6
Pain experienced in last month	4.7	7.9	17.4	-2.5	-3.3	-2.2	-2.7	-1.5	-2.8	-4.2	-2.7	3.6	1.2
Diabetes (father)	4.6	5.7	9.8	2.8	3.0	1.5	2.6	2.3	3.1	2.6	2.7	-1.7	0.4
Glaucoma (self-reported)	4.5	5.3	12.0	-2.2	-2.6	-3.0	-1.4	-1.0	-2.4	-3.1	-1.2	3.5	1.0
Overall health rating	4.3	9.3	19.0	2.1	2.9	3.7	2.5	2.9	2.7	4.2	2.6	-4.4	-1.2
Smoking status: Current	4.0	6.3	10.5	2.6	2.3	3.0	2.2	1.9	2.3	3.0	3.2	-2.9	-0.6
Current tobacco smoking	3.9	6.4	10.7	2.5	2.3	3.0	2.2	1.9	2.2	3.1	3.3	-3.0	-0.8
Medication: Atenolol	3.9	4.9	7.1	-2.2	-2.0	-2.6	-2.7	-1.9	-2.5	-2.3	-1.2	2.1	2.3
Seen doctor (GP) for nerves, anxiety, tension or depression	3.9	5.9	11.4	2.4	2.9	2.6	2.0	1.2	1.9	3.4	2.8	-2.9	-1.5
Medication: Gliclazide	3.9	4.4	6.5	2.4	2.5	2.2	2.0	2.5	2.3	2.4	1.4	-1.5	-1.0
Serious illness, injury or assault to yourself	3.8	4.6	9.6	1.7	2.5	1.8	1.6	2.4	1.7	2.9	3.1	-2.2	-0.2
Gout (self-reported)	3.8	5.2	13.5	-1.9	-2.0	-3.7	-0.7	-3.0	-1.6	-2.2	0.9	1.7	3.1
Leg fat mass (right)	3.7	14.5	33.1	3.0	4.4	5.8	3.5	2.9	3.4	4.8	2.9	-4.1	-1.7
Leg fat percentage (right)	3.6	13.1	28.1	3.0	4.2	5.3	3.5	3.4	3.2	4.5	2.5	-3.4	-2.0
Pulse rate, automated reading	3.6	11.5	22.5	-3.5	-4.2	-1.6	-3.5	-1.7	-2.7	-4.7	-4.7	3.7	1.7
Leg fat mass (left)	3.6	13.9	31.7	2.9	4.3	5.6	3.4	2.6	3.4	4.8	3.0	-4.1	-1.6
Father’s age at death	3.5	4.7	10.4	-2.2	-1.9	-1.3	-2.0	-2.3	-2.2	-2.4	-3.2	2.3	-1.0
Mouth/teeth dental problems: Bleeding gums	3.5	4.5	8.0	2.0	2.5	1.2	2.4	1.2	2.5	2.8	1.7	-2.4	-1.6
Medication: Allopurinol	3.5	4.6	10.3	-2.3	-2.2	-3.2	-0.9	-3.1	-2.2	-1.9	0.3	1.2	2.4
Leg fat percentage (left)	3.5	12.6	26.7	3.0	4.2	5.2	3.5	3.1	3.2	4.5	2.4	-3.4	-1.9
Heel T-Score	3.4	27.4	82.6	5.7	6.7	0.3	3.5	2.7	2.8	9.1	5.6	-5.8	-4.7
Body mass index (BMI)	3.4	14.3	40.6	3.0	4.1	6.4	3.3	2.7	3.7	4.6	1.6	-3.9	-2.4
Mouth/teeth dental problems: Dentures	3.4	5.7	9.6	2.0	2.1	2.7	2.4	1.7	1.9	3.1	2.0	-3.0	-2.7
Mouth/teeth dental problems: Loose teeth	3.3	3.9	6.1	2.2	2.2	0.8	2.5	1.3	2.4	2.5	2.2	-1.8	-1.0
Ever depressed for a whole week	3.3	4.0	7.5	2.4	2.7	1.8	2.3	1.6	2.3	1.9	0.7	-0.8	-2.4
Waist Hip Ratio (WHR)	3.0	13.3	27.4	4.8	3.7	-0.5	3.8	3.8	3.8	4.1	5.2	-2.9	0.4
Heel bone mineral density (BMD) T-score, automated (left)	3.0	6.9	25.4	2.2	3.0	0.5	1.0	0.7	0.6	5.0	2.4	-4.0	-2.4
Ever unenthusiastic/disinterested for a whole week	3.0	3.7	8.3	2.5	2.9	1.7	1.9	1.1	2.5	2.0	1.4	-1.1	-1.1
Comparative body size at age 10	3.0	8.2	20.3	1.9	2.7	4.5	1.5	1.7	2.9	3.6	-0.8	-3.6	-3.3
Long-standing illness, disability or infirmity	3.0	4.6	6.7	1.8	2.0	2.0	2.2	2.5	2.6	2.2	2.6	-2.0	1.1
Illnesses of father: None of the above (group 1)	3.0	3.6	6.6	-2.3	-2.3	-0.8	-2.4	-2.3	-2.0	-1.6	-2.6	0.4	-0.9
Average weekly fortified wine intake	2.9	3.4	5.5	-2.4	-1.8	0.3	-2.2	-2.1	-2.3	-2.1	-1.6	1.7	1.0
Waist circumference	2.9	10.5	19.1	2.8	3.6	3.9	3.0	2.1	3.1	4.4	3.3	-3.9	-1.0
Arm fat-free mass (right)	2.9	15.0	29.5	3.0	4.0	4.9	3.2	1.4	3.0	5.3	4.6	-5.4	-1.1
Impedance of whole body	2.9	14.9	42.0	-3.4	-4.1	-6.5	-3.4	-2.2	-4.0	-4.5	-1.5	4.1	2.7
Arm predicted mass (left)	2.9	14.5	25.7	3.0	4.1	5.1	3.3	1.6	2.9	5.0	4.3	-5.0	-1.6
Reaction Time	2.8	5.3	8.8	2.8	2.5	2.0	2.2	2.6	3.0	2.5	2.0	-1.8	-0.9
Eye problems/disorders: None of the above	2.8	3.2	6.1	2.0	2.4	2.5	1.2	2.1	2.0	1.6	1.7	-0.9	-0.5
Arm predicted mass (right)	2.8	14.1	26.6	2.9	4.0	4.9	3.1	1.5	2.9	5.0	4.5	-5.2	-0.9
Arm fat-free mass (left)	2.8	14.4	26.0	3.0	4.0	5.1	3.2	1.4	2.9	5.1	4.2	-5.0	-1.7
BMI	2.7	15.8	44.8	2.8	4.0	6.7	2.9	2.5	3.1	5.3	0.9	-4.9	-3.5
Birth weight of first child	2.7	5.0	10.6	3.0	3.3	1.8	2.2	2.1	2.4	2.7	1.2	-1.6	-0.7
Knee pain experienced in last month	2.7	4.2	7.9	1.6	2.2	2.4	2.0	1.0	1.9	2.8	2.2	-2.8	-0.2
Breast cancer (self-reported)	2.7	3.2	5.6	-2.4	-1.9	0.3	-2.3	-2.0	-2.2	-1.7	-1.7	0.7	-1.3
Arm fat mass (right)	2.6	10.8	27.1	2.5	3.6	5.2	3.1	2.3	3.2	4.0	2.3	-3.5	-1.7
Neck or shoulder pain in last month	2.6	3.7	8.2	1.8	2.6	2.1	1.2	0.6	1.9	2.9	1.6	-2.5	0.0
Fractured/broken bones in last 5 years	2.6	3.3	13.2	-0.9	-0.7	-0.1	-1.5	0.0	-1.0	-3.0	0.2	3.6	2.6
HDL Cholesterol	2.5	4.2	10.7	-3.0	-2.3	-1.1	-1.6	-0.9	-3.3	-3.2	-1.5	0.0	0.0
Sensitivity / hurt feelings	2.5	4.3	9.2	-2.6	-3.0	-1.5	-2.8	-2.2	-2.7	-1.1	-1.9	-0.7	-0.5
Weight	2.5	12.3	24.9	2.6	3.8	5.0	3.2	1.7	3.0	4.6	3.6	-4.5	-0.8
Mineral and other dietary supplements	2.5	3.3	6.2	1.9	1.9	2.3	1.6	2.5	2.4	1.4	0.2	-1.0	-1.6
Supplements: Fish oil (including cod liver oil)	2.5	3.2	6.3	-2.0	-1.9	-2.0	-1.4	-2.5	-2.1	-1.8	-0.7	1.5	1.6
Body Mass Index (BMI) (2010)	2.4	3.2	7.5	2.0	1.9	1.4	2.4	1.4	2.0	2.7	2.0	0.0	0.0
Arm fat mass (left)	2.4	9.8	25.8	2.2	3.3	5.1	2.9	2.2	2.8	3.9	2.2	-3.5	-1.8
Myopia	2.3	3.4	5.5	-1.8	-1.1	-1.5	-2.2	-2.3	-1.3	-2.0	-2.0	1.8	1.9
Angina	2.2	2.9	7.3	-1.8	-1.5	-2.5	-1.3	-1.5	-1.9	-1.3	-0.1	0.6	2.7
Frequency of unenthusiasm / disinterest in last 2 weeks	2.2	2.9	7.3	1.2	1.6	1.3	0.5	0.7	0.9	2.7	1.0	-2.6	-2.5
Breastfed as a baby	2.2	2.7	4.8	-1.6	-1.5	-1.8	-1.4	-1.6	-1.6	-2.2	-1.6	2.1	0.3
Qualifications: College or University degree	2.2	7.0	14.5	-2.1	-2.8	-2.6	-2.2	-2.2	-2.2	-3.8	-2.0	3.8	1.9
Leg pain on walking	2.2	2.7	4.6	1.8	1.7	1.2	1.9	1.1	1.9	2.1	1.7	-1.9	-0.4
Hearing aid user	2.2	2.5	6.8	-1.7	-2.6	-0.8	-1.5	-0.3	-1.3	-2.2	-1.8	1.2	1.1
Primary Biliary Cirrhosis	2.1	3.0	6.6	1.7	1.4	0.6	2.2	1.2	1.8	2.2	2.0	-2.6	0.8
Systolic blood pressure, automated reading	2.1	6.0	11.8	2.4	2.8	2.3	1.4	1.9	2.3	3.4	3.0	-2.9	0.8
Stomach or abdominal pain in last month	2.1	2.6	5.9	1.1	1.5	1.9	1.3	1.0	0.7	2.4	2.1	-2.4	-0.1
Hayfever/allergic rhinitis (self-reported)	2.1	2.7	11.4	-1.7	-2.4	-3.4	-1.1	-1.7	-1.7	-0.8	-0.1	-0.1	0.0
Mean time to correctly identify matches	2.1	3.9	5.8	2.2	2.2	1.8	2.4	2.3	2.1	2.0	2.0	-1.2	-1.1
Whole body fat mass	2.1	8.9	20.4	1.8	3.1	4.5	2.6	1.8	2.3	4.0	2.7	-3.8	-1.2
Pack years of smoking	2.1	3.1	8.5	1.6	1.8	0.8	1.9	0.8	1.5	2.4	1.0	-1.9	-2.9
Breast Cancer	2.0	4.8	17.0	-0.7	-1.9	-4.1	-1.1	-0.0	0.1	-2.8	-2.3	3.6	-0.2
Rheumatoid Arthritis	2.0	2.7	5.3	-2.0	-2.3	-1.6	-1.3	-1.9	-2.2	-1.1	1.1	-0.7	1.5
Number of incorrect matches in round	2.0	3.3	6.8	-1.9	-1.5	0.9	-1.8	-1.3	-2.6	-2.4	-1.6	2.4	0.3
Heel bone mineral density (BMD) T-score, automated (right)	2.0	4.6	16.6	2.0	2.7	0.3	0.8	0.8	0.5	4.1	2.4	-2.9	-1.4
Medication: Paracetamol	2.0	3.2	10.3	-2.0	-1.8	-1.4	-2.6	-3.2	-1.9	-0.5	-1.5	-0.4	-0.1
Angina (self-reported)	2.0	2.6	6.9	-1.8	-1.4	-2.2	-1.3	-1.5	-1.8	-1.1	-0.2	0.5	2.6
Friendships satisfaction	2.0	2.5	5.9	2.4	2.1	0.9	1.8	1.4	2.4	0.7	1.1	0.5	-0.7
Chronic bronchitis/emphysema (mother)	1.9	2.2	5.5	-2.3	-1.8	0.6	-1.9	-1.9	-1.6	-1.2	-1.0	0.1	0.7
Medication: Omeprazole	1.9	2.2	6.6	0.6	1.5	1.9	2.6	1.3	1.3	1.2	2.0	-0.9	0.3
Chest pain or discomfort	1.9	2.8	7.3	1.9	1.7	0.2	1.8	1.0	1.6	2.3	2.7	-1.3	-0.3
Medication: Atorvastatin	1.9	2.3	6.1	-1.9	-1.6	-1.8	-0.8	-0.9	-1.8	-1.4	-0.0	1.1	2.5
Basal metabolic rate	1.9	10.7	21.0	2.4	3.4	4.6	2.8	1.1	2.5	4.2	4.0	-4.5	-0.6
Deep venous thrombosis (DVT) (self-reported)	1.9	2.4	5.0	-2.0	-1.6	0.7	-2.2	-1.5	-1.8	-1.5	-1.6	1.2	0.5
Crohns Disease (2017)	1.8	3.9	8.8	-2.9	-2.4	0.7	-2.3	-3.0	-2.1	-0.5	-1.6	-1.6	-0.7
Irritable Bowel Disease (IBD)	1.8	4.2	9.1	-2.8	-2.9	0.3	-2.0	-3.0	-1.9	-0.3	-1.8	-2.2	-1.0
Mean Putamen Volume	1.8	2.1	4.0	1.5	1.6	1.8	1.1	1.2	1.2	2.0	0.4	-1.9	-1.1
Pack years adult smoking proportion	1.8	2.8	8.5	1.4	1.7	0.9	1.5	0.8	1.4	2.3	0.6	-1.8	-2.9
Nervous feelings	1.8	3.4	6.4	-2.4	-2.5	-2.3	-2.2	-1.7	-2.2	-1.4	-1.2	0.3	-0.0
Frequency of tenseness / restlessness in last 2 weeks	1.8	2.8	11.6	0.2	0.7	0.6	-0.3	-0.9	-0.1	2.7	1.1	-3.4	-2.3
Medication: Ramipril	1.8	2.3	4.2	1.4	1.1	1.6	2.1	1.6	1.7	1.2	2.0	-1.5	0.5
Trunk fat-free mass	1.8	10.4	19.3	2.5	3.4	3.8	2.8	1.0	2.4	4.2	4.4	-4.4	-0.8
Asthma	1.8	3.6	19.8	1.6	1.4	0.3	1.5	0.9	1.6	2.3	0.4	-0.9	-4.5
Trunk predicted mass	1.8	10.5	19.7	2.5	3.4	3.8	2.9	1.0	2.4	4.2	4.4	-4.4	-0.8
Whole body water mass	1.8	10.2	19.8	2.3	3.2	4.3	2.7	1.1	2.4	4.1	4.1	-4.5	-0.6
Whole body fat-free mass	1.7	9.8	18.6	2.3	3.1	4.3	2.6	1.0	2.4	4.0	4.0	-4.3	-0.5
Average weekly red wine intake	1.7	2.5	6.2	1.7	1.3	-0.8	2.1	2.1	1.3	1.1	2.5	-0.5	-1.3
Hair/balding pattern: Pattern 2	1.6	2.0	4.5	-2.0	-2.1	-0.7	-2.0	-1.3	-1.8	-1.0	-1.1	-0.5	-0.0
Arm fat percentage (right)	1.6	6.1	19.9	1.6	2.7	4.5	2.5	2.0	2.4	2.8	1.1	-2.0	-1.5
Hair/balding pattern: Pattern 3	1.6	2.4	4.6	1.8	2.1	0.0	2.1	1.3	1.6	1.8	0.8	-0.7	-1.7
Age at first live birth	1.6	2.9	6.4	-1.8	-1.6	-1.2	-1.4	-1.1	-2.5	-2.2	-0.8	2.2	1.3
Mood swings	1.6	2.8	12.0	0.9	0.9	1.0	0.4	-0.0	0.7	3.0	1.0	-3.5	-1.6
Loneliness, isolation	1.6	2.2	6.7	1.2	1.4	-0.1	1.0	0.8	1.0	2.3	0.5	-2.1	-2.6
Commuting to job workplace: Walk	1.6	1.7	4.0	-0.8	-1.0	-1.9	-0.7	-0.5	-0.8	-1.7	-1.7	2.0	-0.6
Depressed Affect (Nagel 2018)	1.5	3.2	11.3	1.6	1.6	0.2	0.8	0.5	1.2	3.1	1.5	-3.4	-1.1
Systolic Blood Pressure	1.5	7.5	11.9	3.4	3.3	1.7	1.7	2.3	3.2	3.5	3.0	-2.7	1.9
Eye problems/disorders: Diabetes related eye disease	1.5	1.7	5.0	1.3	1.6	0.2	1.1	0.8	0.9	2.2	1.2	-1.7	-0.5
Medication: Co-codamol	1.5	1.8	6.2	0.5	1.2	2.5	1.1	0.8	1.0	1.4	1.3	-1.7	0.6
Worrier / anxious feelings	1.5	2.9	6.1	-2.1	-1.7	-1.0	-2.5	-2.2	-2.1	-0.9	-2.0	0.1	-0.9
Body fat percentage	1.5	5.7	15.0	1.4	2.5	3.9	2.2	1.8	1.9	3.2	1.7	-2.8	-1.2
Age at last live birth	1.5	2.1	3.3	-1.4	-1.7	-1.8	-1.1	-1.3	-1.7	-1.8	-0.8	1.7	0.8
Illness, injury, bereavement, stress in last 2 years	1.5	1.8	4.1	-1.6	-1.6	0.1	-1.0	-1.0	-1.0	-2.0	-1.7	1.5	0.4
Arm fat percentage (left)	1.5	5.8	18.5	1.5	2.5	4.3	2.3	2.0	2.2	2.9	1.0	-2.3	-1.5
Supplements: Calcium	1.5	1.7	4.0	-1.5	-1.6	-2.0	-1.1	-1.2	-0.8	-1.7	-0.5	1.2	0.8
Schizophrenia (2018)	1.4	2.9	5.6	1.1	1.4	2.0	1.6	1.5	1.3	2.2	2.4	-2.1	0.3
Other serious medical condition/disability diagnosed by doctor	1.4	1.8	3.5	1.0	1.3	1.0	1.3	0.8	1.7	1.5	1.9	-1.4	1.1
Financial difficulties in last 2 years	1.4	1.9	8.2	1.3	0.7	-0.0	0.3	-0.1	1.0	2.4	1.0	-2.9	-1.0
Alcohol intake versus 10 years previously	1.4	2.1	10.2	0.5	1.0	-0.3	0.4	0.4	0.5	1.2	2.3	-1.3	3.2
Handedness (chirality/laterality): Left-handed	1.4	1.7	2.8	-0.7	-0.9	-1.1	-1.2	-1.7	-1.1	-1.7	-1.5	1.6	-1.0
Bipolar Disorder or Schizophrenia	1.3	3.3	9.1	1.3	1.4	2.5	2.0	1.4	1.6	1.6	3.0	-1.5	0.7
Fasting Glucose	1.3	1.6	4.3	0.6	1.6	0.9	0.2	0.8	1.3	2.1	0.1	-1.8	-1.6
Lupus	1.3	1.9	4.5	0.8	1.7	0.6	1.3	0.7	1.0	2.1	2.0	-2.0	-0.2
Smoking Status	1.3	3.1	11.4	1.1	0.9	0.8	1.1	-0.3	1.4	2.4	2.7	-3.4	0.4
Impedance of leg (right)	1.3	6.3	28.0	-1.7	-2.3	-5.3	-2.1	-1.1	-2.8	-2.4	-0.1	2.4	1.6
Impedance of leg (left)	1.3	6.1	30.1	-1.4	-2.1	-5.5	-1.9	-1.3	-2.6	-2.3	-0.1	2.3	1.7
Trunk fat mass	1.3	5.6	14.1	0.9	2.2	3.8	2.0	1.1	1.5	3.3	2.4	-3.5	-0.8
Happiness	1.3	1.6	3.2	1.8	1.6	1.5	0.9	0.2	1.3	1.0	1.7	-0.4	1.1
Blood clot in the leg (DVT)	1.3	1.6	3.0	-1.6	-1.1	1.2	-1.7	-1.1	-1.5	-1.2	-1.2	1.1	0.4
Headache pain in last month	1.3	2.2	8.2	-0.5	-0.7	-1.3	-1.1	-1.3	-1.3	1.3	-1.4	-1.7	-2.9
Wheeze or whistling in the chest in last year	1.3	2.3	5.9	1.8	1.7	0.7	1.7	1.6	1.5	1.5	1.0	-0.2	-2.4
Number of children fathered	1.3	1.5	8.3	-0.2	0.0	0.5	0.7	-0.6	0.1	1.6	1.4	-2.9	-0.6
Medication: Ibuprofen	1.3	1.5	3.8	-1.8	-1.2	-0.1	-1.9	-1.3	-2.0	-0.5	-0.8	-0.6	0.2
Alcohol drinker status: Never	1.3	1.5	3.8	-1.9	-0.9	0.4	-1.4	-1.3	-1.5	-1.0	-1.8	0.7	-0.1
Prostate Cancer	1.2	1.7	3.5	1.1	1.6	1.9	1.7	1.0	1.9	0.8	1.3	-0.5	0.3
Lung FEV1/FVC ratio	1.2	6.3	39.6	2.1	1.5	1.9	1.3	1.5	2.0	-1.2	0.3	2.0	6.3
Leg fat-free mass (left)	1.2	6.4	17.6	1.5	2.4	4.2	1.9	0.8	2.0	3.1	2.9	-3.5	-0.0
Fed-up feelings	1.2	2.1	13.0	0.0	0.4	-0.4	-0.3	-0.9	0.2	2.5	0.2	-3.6	-1.0
Leg predicted mass (left)	1.2	6.2	18.1	1.4	2.3	4.3	1.9	0.7	1.9	3.1	2.9	-3.4	-0.1
Medication: Simvastatin	1.2	1.7	3.6	1.3	1.6	0.5	1.8	1.9	1.6	1.0	1.5	-0.6	0.2
Falls in the last year	1.2	1.7	4.4	-1.2	-1.2	-0.8	-1.1	-0.7	-0.8	-2.0	-1.4	2.1	0.8
Pulse rate	1.2	2.1	7.4	-0.8	-1.5	-0.4	-1.5	-0.1	-0.7	-2.0	-2.7	1.6	0.9
Medication: Ibuprofen (e.g. Nurofen)	1.2	1.5	3.3	-1.8	-1.4	-0.6	-1.6	-1.8	-1.8	-0.2	-0.2	-0.9	-0.0
Medication: Ventolin 100micrograms inhaler	1.2	1.5	8.6	1.0	0.7	-0.3	0.7	0.8	0.3	1.6	0.4	-0.9	-2.9
Forced vital capacity (FVC), Best measure	1.2	4.5	16.6	0.9	1.1	-2.1	1.4	-0.4	0.5	2.8	4.1	-3.4	-0.5
Osteoporosis (self-reported)	1.2	1.4	4.7	-0.4	-0.6	-0.2	-2.2	0.5	-0.6	-1.5	-2.0	1.5	-0.1
Ever had prostate specific antigen (PSA) test	1.2	1.4	2.7	-1.6	-1.6	-1.4	-0.4	-1.3	-1.3	-1.6	-0.5	-0.0	0.6
Blood White Count	1.1	8.1	15.0	-3.4	-3.7	-3.9	-3.1	-3.0	-1.5	-3.4	-1.4	2.3	1.0
Respiratory disease	1.1	2.6	19.8	0.3	-0.3	-1.1	0.4	-0.1	-0.2	1.6	0.2	-1.3	-4.4
Lung FVC	1.1	5.5	18.7	0.8	0.8	-0.9	1.9	-0.1	0.2	3.5	4.3	-4.0	-1.6
Medication for hormone replacement therapy	1.1	1.2	3.5	-1.3	-1.3	0.3	-1.3	-1.0	-1.2	-0.6	-1.9	0.3	-0.8
Multivitamins +/- minerals	1.1	1.4	4.4	-1.1	-1.1	-2.1	-1.4	-1.4	-1.2	0.3	-0.1	-1.0	0.8
Tense / ‘highly strung’	1.1	1.9	5.3	-1.7	-1.2	-0.2	-1.9	-2.3	-1.5	0.7	-0.4	-1.3	-0.7
High blood pressure (siblings)	1.1	1.6	3.2	1.3	1.8	1.6	0.3	-0.0	0.9	1.7	1.8	-1.1	0.5
Exposure to tobacco smoke outside home	1.1	1.4	6.6	0.6	0.3	-0.1	-0.8	-0.6	0.4	1.6	-1.1	-1.5	-2.6
Qualifications: NVQ or HND or HNC or equivalent	1.1	1.3	2.7	1.6	1.6	1.6	-0.2	1.2	1.6	0.7	0.3	-0.1	0.8
Illnesses of father: Heart disease	1.1	1.5	2.7	1.1	1.4	0.3	1.4	1.1	1.0	0.1	1.6	1.6	1.4
Leg fat-free mass (right)	1.1	6.0	15.7	1.4	2.3	4.0	1.9	0.5	1.9	3.0	2.8	-3.5	0.0
Asthma (self-reported)	1.1	2.2	14.9	1.0	0.9	0.1	1.0	0.6	1.0	1.8	0.2	-0.5	-3.9
Leg predicted mass (right)	1.1	5.8	15.8	1.4	2.2	4.0	1.8	0.4	1.8	3.0	2.7	-3.5	-0.0
Average weekly champagne plus white wine intake	1.1	1.6	4.6	-0.6	-1.0	-1.5	-0.9	-0.7	-1.6	-1.8	-0.2	2.1	0.5
Miserableness	1.1	1.8	4.5	1.5	1.4	-0.5	1.2	0.4	1.5	2.1	1.2	-2.0	-0.3
Medication: Paracetamol	1.1	1.7	4.9	-1.4	-1.1	-0.5	-1.9	-2.2	-1.4	0.1	-1.4	-0.8	-0.7
Schizophrenia (2014)	1.0	2.3	6.4	0.1	0.7	2.0	1.0	0.5	0.2	2.0	2.3	-2.5	1.1
Ulcerative Colitis	1.0	1.4	4.6	-1.4	-2.1	-1.2	-0.5	-1.2	-1.1	-0.6	-1.1	-1.0	-0.9
Relative age of first facial hair	1.0	2.0	9.8	-1.1	-0.5	2.2	-1.5	0.2	-0.3	-0.9	-3.1	0.7	-0.4
Serious illness, injury or assault of a close relative in last 2 years	1.0	1.2	4.1	1.2	0.9	-0.7	0.6	1.1	1.3	0.2	-1.2	0.6	-2.0
Pulse wave Arterial Stiffness index	1.0	1.2	2.0	-1.3	-1.4	-1.4	-0.5	-1.2	-0.9	-0.2	-0.9	-1.0	1.3
Migraine (self-reported)	1.0	1.2	2.8	1.4	1.0	0.2	0.5	0.9	1.2	1.4	-0.7	-1.2	-1.7
Illnesses of siblings: Diabetes	1.0	1.2	2.6	1.3	1.2	0.5	1.2	0.6	1.5	1.6	1.0	-1.0	-0.1
Schizophrenia vs Biploar Disorder	0.9	1.1	3.3	0.7	1.1	0.8	1.0	1.8	1.0	1.3	0.8	-1.1	-0.2
Major Depression (MDD)	0.9	1.1	4.1	0.3	0.9	1.4	0.2	0.6	-0.1	1.1	2.0	-1.5	0.3
Crohns Disease (2012)	0.9	1.4	3.9	-1.6	-1.3	1.0	-0.7	-2.0	-1.2	-0.1	-0.1	-1.1	-1.4
Average weekly spirits intake	0.9	1.2	7.6	-0.1	0.8	2.8	0.6	0.5	0.5	1.2	0.3	-1.0	0.1
Ever used hormone-replacement therapy (HRT)	0.9	1.2	3.6	-1.5	-1.2	0.5	-0.7	-1.1	-1.9	-1.1	0.0	1.1	-0.5
Sitting height	0.9	6.6	15.8	2.4	2.8	0.2	2.5	0.7	2.1	3.5	4.0	-3.6	0.4
Had menopause	0.9	1.1	3.2	-0.8	-0.9	-0.7	-0.7	-0.8	-1.6	-1.6	0.1	1.8	-0.2
Forced vital capacity (FVC)	0.9	3.5	12.4	0.0	0.1	-2.1	0.8	-0.9	-0.3	2.3	3.5	-3.4	0.0
Ever highly irritable/argumentative for 2 days	0.9	1.1	2.5	1.0	0.9	1.0	0.7	0.0	0.8	1.5	-0.0	-1.6	-1.4
Ever had stillbirth, spontaneous miscarriage or termination	0.9	0.9	3.0	-0.5	-0.7	-1.7	-0.4	-1.5	-1.5	-0.7	0.0	0.4	0.5
Osteoarthritis (self-reported)	0.9	1.1	8.3	-0.2	-0.1	-0.3	-0.5	-0.8	0.4	-0.5	1.1	0.4	2.9
Medication: Blood pressure	0.9	1.7	5.3	1.1	1.0	-0.1	1.3	0.4	1.2	1.0	2.1	-0.8	2.3
Average weekly beer plus cider intake	0.9	1.4	3.0	1.7	1.4	0.3	0.9	1.2	1.7	0.7	1.3	0.0	1.1
Vitamin and mineral supplements	0.8	1.1	2.0	1.0	0.9	1.3	1.4	1.4	1.1	-0.6	-0.2	1.3	-0.4
Hand grip strength (right)	0.8	2.2	8.5	-1.0	-0.8	-1.2	-1.3	-2.0	-0.3	1.5	-0.6	-2.9	-1.3
Length of working week for main job	0.8	0.9	3.8	0.2	0.6	0.5	0.2	-0.3	0.5	1.6	-0.2	-2.0	-1.1
Number of full brothers	0.8	1.0	3.4	1.0	1.0	-0.2	1.2	0.8	0.7	1.0	1.8	-0.5	-0.9
Pulse wave peak to peak time	0.8	0.9	1.5	1.1	1.2	1.1	0.3	1.0	0.8	-0.0	1.0	1.1	-1.2
Heart disease (mother)	0.8	1.0	3.7	-0.7	-0.4	-0.6	-0.2	-1.2	-0.6	-0.9	1.0	1.3	1.9
Medication: Aspirin	0.8	1.0	1.8	-1.1	-1.3	-1.0	-0.6	-1.2	-1.2	-1.0	-0.9	0.8	0.8
Financial situation satisfaction	0.8	1.1	2.5	1.6	1.6	0.7	-0.1	0.6	1.2	1.4	0.7	-0.9	0.3
Age started oral contraceptive pill	0.8	1.0	4.6	-0.3	-0.6	0.5	-0.4	0.8	-0.1	-1.6	-0.7	2.1	1.1
Depression (Nagel 2018)	0.7	1.0	3.1	-0.1	0.7	0.6	-1.0	-0.5	-0.3	1.6	0.4	-1.8	-1.5
Worry (Nagel 2018)	0.7	1.4	2.8	-1.7	-1.3	-0.8	-1.4	-1.6	-1.4	0.1	0.1	-1.1	-1.0
Ulcerative Colitis (UC)	0.7	1.3	4.4	-1.5	-2.1	0.2	-0.5	-1.4	-0.8	-0.2	-0.9	-1.7	-0.2
Blood Red Count	0.7	6.7	29.6	1.3	1.0	-0.3	3.0	-0.3	3.0	3.7	0.4	-5.4	-1.6
Allergy or Eczema	0.7	1.7	10.2	0.4	-0.9	-3.2	0.5	0.0	-0.6	0.3	1.9	0.3	-1.2
Neuroticism	0.7	1.6	4.5	-0.8	-0.4	-1.1	-1.1	-1.9	-1.1	1.3	-0.0	-2.1	-1.5
Chronotype (morning person)	0.7	1.6	4.1	0.2	-0.5	-2.0	-0.9	0.7	-0.1	-1.7	-0.3	1.9	1.9
Frequency of depressed mood in last 2 weeks	0.7	0.9	3.4	0.4	0.9	0.9	-0.1	0.5	0.4	1.7	0.8	-1.8	-0.6
Qualifications: CSEs or equivalent	0.7	0.9	2.4	0.5	0.4	0.8	-0.1	0.6	0.6	1.2	1.5	-1.5	1.2
Past tobacco smoking	0.7	1.3	5.0	-0.6	-0.6	-0.3	-0.7	0.7	-0.9	-1.5	-1.6	2.2	-0.5
Neuroticism score	0.7	1.4	5.3	-0.7	-0.5	-1.2	-1.1	-1.4	-0.9	1.3	-0.0	-2.3	-1.0
Hair/balding pattern: Pattern 4	0.7	1.6	6.2	-0.3	-0.6	-1.5	-1.0	0.5	-1.0	-1.8	-0.9	2.5	1.0
Peak expiratory flow (PEF)	0.7	1.7	6.9	0.4	0.5	0.2	0.8	-0.3	0.2	1.0	2.6	-1.4	2.5
Pulse wave reflection index	0.7	0.9	4.4	-0.6	-0.3	-1.1	-0.0	-1.0	-0.7	1.1	-0.2	-2.1	-0.3
Medication for pain relief, constipation, heartburn	0.7	1.1	5.6	1.2	0.6	0.3	1.2	2.4	1.0	-0.6	0.1	1.0	-0.1
Qualifications: nursing, teaching	0.7	1.0	2.1	-0.7	-1.0	-1.1	-0.6	-1.0	-0.8	-1.1	-1.0	1.4	-1.1
Diastolic blood pressure, automated reading	0.7	2.0	12.8	-0.2	0.1	0.2	-0.3	-0.4	0.1	0.9	2.0	-1.4	3.6
Medication: Omeprazole (e.g. Zanprol)	0.7	0.8	2.5	-0.3	0.4	1.3	1.5	0.1	0.1	0.7	1.6	-0.8	0.5
Bipolar Disorder (2018)	0.6	0.9	3.7	0.7	0.6	1.4	1.2	0.3	0.8	-0.2	1.9	0.2	0.8
Verbal and Numeric Reasoning (VNR)	0.6	1.4	3.0	-1.7	-1.6	-1.5	0.2	-1.7	-0.9	-0.6	-1.1	-0.3	-0.8
LDL Cholesterol	0.6	1.0	2.3	0.8	1.2	0.6	1.2	1.3	1.3	1.5	-0.3	0.0	0.0
Hand grip strength (left)	0.6	1.7	4.1	-1.4	-1.2	-0.9	-2.0	-2.0	-0.9	0.5	-0.5	-1.8	-0.5
Ever had hysterectomy (womb removed)	0.6	0.6	2.5	-0.7	-0.5	1.4	-0.8	0.2	-0.4	-0.5	-0.2	0.2	1.6
Trunk fat percentage	0.6	2.6	8.4	0.3	1.4	2.9	1.4	0.9	0.8	2.2	1.4	-2.2	-0.5
Maternal smoking around birth	0.6	0.8	2.8	-0.6	-0.4	0.3	-1.2	-1.3	-0.8	-0.3	-1.7	0.1	-1.0
Alcohol usually taken with meals	0.6	1.0	2.6	-0.6	-0.7	-1.6	-1.2	-1.6	-1.2	-0.3	-0.4	0.2	-0.9
Frequency of tiredness / lethargy in last 2 weeks	0.6	1.0	6.4	-0.1	0.2	-0.2	0.1	-0.3	0.3	1.8	0.4	-2.5	-0.5
Forced expiratory volume in 1-second (FEV1)	0.6	2.1	8.4	0.2	0.1	-1.6	0.8	-0.7	-0.2	0.9	2.9	-1.6	2.2
Medication: Cholesterol lowering	0.6	0.9	3.7	0.1	0.6	-0.0	1.4	1.3	0.4	0.3	1.9	0.1	1.1
Depression (self-reported)	0.6	0.7	4.1	-0.2	0.3	0.1	0.1	-0.7	-0.4	1.1	2.0	-0.8	-0.2
Forced expiratory volume in 1-second (FEV1), Best measure	0.6	2.0	9.7	0.6	0.7	-1.3	1.0	-0.5	0.1	1.1	3.1	-1.5	1.8
Medication: Amlodipine	0.6	0.9	2.7	-0.4	-0.7	-0.6	-0.9	-1.6	-1.0	-1.0	0.5	1.2	0.8
Comparative height size at age 10	0.6	3.4	14.9	-1.1	-0.8	-1.8	-0.3	-1.8	-0.9	-0.5	3.9	-1.1	3.0
Supplements: Vitamin C	0.6	0.7	2.2	-1.2	-0.7	-0.3	-0.6	-0.9	-1.5	0.2	0.7	-0.9	-0.2
Ever had bowel cancer screening	0.6	0.7	2.9	0.4	0.7	1.7	1.1	1.1	0.6	0.0	0.8	0.2	0.4
Eye problems/disorders: Cataract	0.6	0.6	1.8	-1.0	-1.1	-1.0	0.6	-1.3	-0.8	-0.3	-0.4	-0.1	-0.4
Mouth/teeth dental problems: Mouth ulcers	0.6	1.0	7.3	-0.3	-0.5	-2.7	0.3	-0.9	-0.1	-0.8	-0.2	0.8	0.2
Wears glasses or contact lenses	0.6	0.6	1.3	-1.0	-1.0	0.6	-0.5	-0.3	-0.9	-0.8	-1.0	0.3	-1.1
Commuting to job workplace: Public transport	0.6	0.7	4.3	0.3	0.8	-2.1	-0.8	-0.4	0.1	0.7	-0.9	-0.1	-0.2
Ever smoked	0.6	1.1	4.0	0.7	0.4	-0.1	0.7	-0.6	0.5	1.4	2.0	-1.9	-0.0
Irritability	0.6	1.0	3.3	0.6	1.1	0.3	-0.1	-0.7	0.0	1.8	1.1	-1.6	-0.9
Commuting to job workplace: Cycle	0.6	0.7	4.1	-0.4	-0.0	-0.1	-0.4	-0.2	-0.1	-1.3	0.0	1.1	2.0
Neuroticism (Nagel 2018)	0.5	1.1	5.1	-0.1	0.2	-0.4	-0.5	-0.7	-0.3	1.7	0.6	-2.2	-1.4
Height	0.5	9.7	32.4	-1.9	-1.0	-3.5	-1.0	-3.8	-3.0	0.2	5.7	-2.0	4.5
Cardiovascular Disease	0.5	1.5	2.7	0.9	1.3	0.4	1.6	0.8	1.5	1.3	1.6	-1.3	1.1
Relative age voice broke	0.5	0.7	2.9	0.1	-0.2	1.7	0.1	1.3	0.6	-0.5	-1.2	0.4	0.3
Tinnitus: Yes, but not now, but have in the past	0.5	0.5	1.6	0.6	1.2	0.9	0.5	-0.0	0.3	0.6	1.3	-0.0	-0.2
Pain all over the body in last month	0.5	0.5	2.5	0.2	1.0	1.6	0.1	0.3	0.4	0.7	0.5	-0.5	0.7
Hip circumference	0.5	2.1	8.8	-1.0	0.4	3.0	-0.1	-0.9	-0.1	1.6	0.6	-2.6	-0.1
Time employed in main current job	0.5	0.5	2.6	-0.6	-0.4	-1.6	-0.5	-0.7	-0.8	-0.5	0.2	0.8	-0.3
Number of live births	0.5	0.7	2.8	-0.6	-1.3	-0.2	-0.2	-0.9	-1.2	-0.6	-0.1	0.1	-1.7
Noisy workplace	0.5	0.6	4.6	-0.2	0.3	2.2	-0.2	0.0	-0.3	0.4	-0.2	-0.5	-0.7
Prospective memory result	0.5	0.6	3.0	-0.9	-0.5	1.7	-0.7	0.5	-0.8	-0.4	-0.4	0.6	-0.1
Illnesses of mother	0.5	0.6	2.7	-0.3	-1.0	-1.6	0.3	0.5	-0.0	-0.8	-1.1	0.2	-0.7
Standing height	0.5	4.8	22.1	-0.6	-0.4	-2.6	-0.1	-2.0	-1.3	0.5	4.7	-2.0	2.9
Exposure to tobacco smoke at home	0.5	0.5	1.5	0.3	0.6	0.9	-0.6	-0.4	0.6	0.6	-1.2	-0.2	-1.1
Reason for reducing amount of alcohol drunk: Health precaution	0.5	0.5	3.2	0.2	0.2	-0.1	0.4	0.4	0.7	-0.4	-0.4	0.9	-1.8
Suffer from ‘nerves’	0.5	0.7	1.9	-0.7	-0.7	-1.4	-1.3	-0.9	-1.0	-0.2	0.4	-0.4	-0.8
Had major operations	0.5	0.5	1.7	-0.1	0.6	-0.3	0.7	-0.3	-0.0	1.0	0.7	-1.3	-1.0
Commuting to job workplace: Car/motor vehicle	0.5	0.6	3.1	0.3	0.3	1.8	0.9	0.2	0.4	0.4	1.3	-0.3	-0.2
Smoking status: Previous	0.5	0.8	3.1	0.5	0.5	0.2	0.5	-0.8	0.9	1.1	0.8	-1.8	0.5
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.5	0.6	2.2	-0.4	-0.2	-0.8	-0.6	-1.5	-0.1	-0.5	0.2	0.5	1.4
Back pain experienced in last month	0.5	0.7	4.1	-0.2	-0.2	0.0	0.2	-0.3	0.3	1.3	0.9	-2.0	-0.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.5	1.0	2.5	0.6	0.6	0.6	1.6	1.5	0.4	0.5	1.4	-0.6	1.4
Guilty feelings	0.5	0.8	3.3	-0.5	-0.5	-1.8	-0.3	-1.3	-1.0	0.1	1.0	-0.7	-0.1
Pain type(s) experienced in last month: Hip pain	0.5	0.6	2.9	-0.0	-0.2	0.0	0.6	-0.3	-0.2	1.0	1.3	-1.7	0.3
Unable to work because of sickness or disability	0.5	0.6	1.6	-1.1	-0.4	-0.3	-0.7	-1.3	-1.0	-0.1	0.6	-0.3	1.2
Alzheimer’s Disease (in mother)	0.4	0.5	1.4	-1.0	-0.8	-0.5	-0.1	-0.5	-1.2	-0.5	-0.1	0.3	-1.1
Ovarian Cancer	0.4	0.6	1.4	0.4	0.5	0.0	0.7	1.1	-0.2	1.0	1.2	-1.0	-0.5
Bipolar Disorder (2011)	0.4	0.4	2.4	-0.2	-0.3	0.9	-0.3	-1.6	-0.8	0.2	0.5	0.0	0.0
Coronary Artery Disease (CAD)	0.4	0.5	1.3	-0.3	-0.9	-0.6	-1.1	-1.1	-0.4	-1.1	-0.3	0.0	0.0
Triglycerides	0.4	0.7	3.7	1.3	0.8	-0.2	-0.1	0.1	0.9	1.9	0.0	0.0	0.0
Hypothyroidism (self reported)	0.4	1.0	5.5	-0.4	-0.3	-2.3	-0.4	-1.3	-0.9	-0.4	0.0	1.0	-0.1
Supplements: Zinc	0.4	0.5	1.0	-0.8	-0.7	-0.5	-0.9	-1.0	-0.4	0.1	-1.0	-0.7	0.0
Taking other prescription medications	0.4	0.7	2.7	0.1	0.3	-0.1	1.2	-0.1	0.8	0.8	1.6	-1.0	0.4
Bilateral oophorectomy (both ovaries removed)	0.4	0.5	1.6	-0.1	-0.0	1.3	-0.1	0.4	0.1	1.0	-0.0	-1.3	0.8
Hayfever, allergic rhinitis or eczema	0.4	0.9	6.3	0.0	-0.7	-2.5	-0.1	-0.0	-1.1	0.0	1.1	0.5	-0.3
Supplements: Glucosamine	0.4	0.5	1.8	-0.3	-0.7	-1.4	-0.1	-1.0	-0.8	0.0	0.7	-0.1	0.4
Diverticular disease/diverticulitis (self-reported)	0.4	0.4	1.3	-0.6	-1.0	-0.3	-0.4	-0.3	-0.6	-0.9	-1.1	0.5	-0.1
Medication: Levothyroxine sodium	0.4	0.6	2.7	-0.0	0.1	-1.7	0.3	-1.1	-0.6	0.5	1.2	-0.3	-0.0
High blood pressure (mother)	0.4	0.6	1.3	1.1	1.1	0.7	-0.4	-0.0	0.7	1.0	0.5	-0.7	-0.4
Heart attack	0.4	0.5	1.7	0.0	-0.3	-1.1	1.3	-0.1	0.2	-0.3	0.7	-0.0	1.0
Allergy	0.4	1.0	3.4	0.3	0.9	1.8	0.3	0.7	1.1	-0.4	-0.5	0.0	1.8
Lung cancer (father)	0.4	0.5	1.8	-0.7	-0.1	1.0	-0.2	-0.9	-0.3	-0.3	0.1	-0.4	1.4
Loud music exposure frequency	0.4	0.4	1.9	-0.7	-0.7	-0.3	-0.1	-0.6	-0.5	-0.5	-0.5	0.6	-1.4
Qualifications: O levels/GCSEs or equivalent	0.4	0.7	1.6	1.0	1.3	0.2	1.2	-0.2	1.0	0.8	1.1	-0.1	-0.3
Number of full sisters	0.4	0.4	1.8	0.2	-0.4	-0.2	0.5	0.7	-0.2	-1.2	0.5	1.3	-0.0
Ever taken oral contraceptive pill	0.4	0.5	1.2	-0.5	0.1	-1.1	0.6	-0.8	-0.7	0.8	0.7	-0.6	-0.7
Tinnitus: Yes, now most or all of the time	0.4	0.4	2.2	0.3	0.3	0.1	0.0	-0.0	0.5	-0.4	-1.0	0.7	-1.5
Medication: Bendroflumethiazide	0.4	0.6	2.8	0.6	0.2	0.3	0.2	0.7	0.8	1.1	0.4	-1.7	-0.0
Illnesses of father: High blood pressure	0.4	0.5	1.2	-0.2	-0.8	-1.1	-0.9	-0.4	-0.3	-0.8	-1.0	0.6	-0.4
Cholesterol lowering medication	0.4	0.6	1.3	0.3	0.8	0.3	0.9	-0.1	0.8	1.1	0.1	-1.1	-1.0
Basal cell carcinoma (self-reported)	0.4	0.5	2.2	0.6	0.5	0.1	0.1	0.5	0.4	-0.9	-1.2	1.5	-0.1
Alcohol drinker status: Previous	0.4	0.4	1.5	-1.2	-0.4	-1.0	-0.5	-0.5	-0.1	-0.2	-0.9	-0.3	-0.3
Intelligence (Savage-Jansen 2018)	0.3	0.8	5.3	-0.2	-0.2	-2.3	0.7	-0.6	0.1	0.3	-0.6	-0.3	-1.2
Alzheimer’s Disease (in father)	0.3	0.3	1.1	0.3	0.1	-0.6	1.0	0.4	0.0	-0.1	1.1	0.0	0.6
Alzheimer’s Disease (including proxy)	0.3	0.4	2.4	-0.1	0.0	-0.7	1.0	0.3	-0.2	0.1	0.6	0.1	-1.6
Age at First Birth	0.3	0.4	1.3	-0.2	-0.0	-0.8	0.2	-1.1	-0.5	0.1	0.8	0.0	1.1
Hearing difficulty/problems: Yes	0.3	0.4	1.4	0.5	0.4	-0.2	0.7	0.7	0.3	-0.4	-0.3	0.8	-1.2
Severe depression (siblings)	0.3	0.3	0.8	0.0	-0.3	0.3	-0.9	-0.9	-0.3	-0.3	-0.7	0.2	-0.9
Townsend deprivation index at recruitment	0.3	0.4	1.3	-0.8	-0.3	-0.5	-0.4	-0.7	-0.4	1.0	0.5	-1.1	-0.1
Chronic bronchitis/emphysema (father)	0.3	0.3	0.8	0.4	0.8	0.6	0.2	0.5	0.6	0.9	-0.3	-0.6	-0.3
Had other major operations	0.3	0.4	0.9	-0.8	-0.3	0.2	-0.5	-0.5	-0.9	-0.8	0.0	0.9	0.1
Fluid intelligence score	0.3	0.6	3.4	-0.6	-0.7	-1.8	0.3	-0.6	-0.4	-0.4	-0.5	0.4	0.8
Illnesses of siblings	0.3	0.5	1.3	-0.5	-1.1	-1.0	0.1	0.8	0.0	-0.8	-0.8	-0.1	0.2
Medication for cholesterol, blood pressure or diabetes	0.3	0.6	1.7	-0.2	-0.6	-0.3	-0.9	-0.8	-0.3	-0.0	-1.3	-0.6	-1.2
Hypothyroidism/myxoedema (self-reported)	0.3	0.6	2.9	0.4	0.4	-1.7	0.7	-0.6	-0.2	0.3	1.4	0.3	0.3
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.4	1.3	-0.4	-0.1	-0.1	-0.6	-1.1	-1.0	-0.0	1.0	-0.3	0.7
Medication: Seretide 50 evohaler	0.3	0.3	1.1	-0.8	-1.1	0.2	-0.6	-0.4	-0.8	-0.3	0.2	-0.1	-0.5
Medication: Aspirin	0.3	0.4	0.9	-0.8	-1.0	-0.7	-0.3	-0.9	-0.7	-0.3	-0.6	0.1	0.3
Medication: Lisinopril	0.3	0.4	1.2	0.2	0.3	-0.5	-0.4	-0.6	-0.5	-0.4	0.6	1.1	1.1
Risk taking	0.3	0.5	1.0	1.0	0.8	0.1	0.7	0.8	0.7	0.9	0.8	-0.4	0.2
Heart attack/myocardial infarction (self-reported)	0.3	0.4	1.5	0.0	-0.3	-0.9	1.2	-0.2	0.1	-0.5	0.7	0.1	1.1
Neuroticism (2016)	0.2	0.3	1.1	0.5	0.2	-0.7	-0.8	0.1	-0.1	0.7	0.4	-1.1	-0.4
Hair Pigment	0.2	7.1	15.4	-3.3	-1.9	1.8	-2.3	-2.4	-3.2	-3.9	-2.0	3.3	-0.7
High blood pressure	0.2	0.6	1.6	0.5	0.9	0.1	0.5	-0.0	0.8	0.8	1.3	-0.5	1.3
Hearing difficulty/problems with background noise	0.2	0.3	2.4	-0.3	-0.3	-0.5	0.3	0.0	-0.4	-0.4	-0.2	0.5	-1.6
Medication: Lansoprazole	0.2	0.3	1.6	0.2	-0.0	1.3	0.6	0.3	0.6	0.4	-0.2	-0.5	0.0
Worry too long after embarrassment	0.2	0.4	1.6	0.3	0.0	-0.5	-0.2	-0.2	0.0	0.3	-1.2	-0.7	-1.2
Medication: Blood pressure	0.2	0.4	1.5	-0.4	-0.4	-0.7	-0.6	-0.3	-0.2	-0.6	0.1	0.8	1.2
Alcohol intake frequency.	0.2	0.5	1.6	-0.7	0.2	0.7	-0.4	-0.3	-0.2	0.5	0.3	-1.1	1.3
Hypertension (Self-reported)	0.2	0.5	3.0	-0.1	0.2	-0.5	0.2	-0.5	0.4	0.3	1.0	-0.2	1.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.2	0.3	1.0	-0.2	0.2	1.0	0.8	0.2	0.8	0.0	0.1	-0.4	0.4
Medication for cholesterol	0.2	0.3	0.8	-0.2	-0.4	0.3	-0.7	0.4	-0.6	-0.9	-0.0	0.8	0.1
Mother’s age at death	0.2	0.3	0.9	-0.3	0.2	0.7	0.1	0.0	-0.8	-0.6	0.4	1.0	-0.2
High cholesterol (Self-reported)	0.2	0.4	1.6	-0.0	0.4	-0.1	1.2	0.7	0.7	-0.0	0.5	0.1	-0.9
Number of operations (self-reported)	0.2	0.2	0.4	-0.5	-0.0	0.7	0.4	-0.5	-0.5	0.3	0.6	-0.6	-0.4
Vascular/heart problems diagnosed by doctor	0.2	0.5	2.8	0.2	-0.3	0.3	-0.1	0.6	0.0	-0.4	-1.1	0.4	-1.7
Heart disease (siblings)	0.2	0.2	0.8	-0.1	0.5	0.4	-0.1	-0.1	-0.1	0.6	0.4	-0.2	-0.9
HbA1C	0.1	0.1	0.5	0.3	0.5	-0.3	0.0	0.2	0.3	0.7	-0.4	-0.4	-0.1
Number of treatments/medications taken	0.1	0.2	0.7	-0.4	-0.0	0.5	0.0	-0.6	-0.4	0.5	0.8	-0.5	0.3
Qualifications: None of the above	0.1	0.3	0.9	-0.9	-0.7	0.3	0.2	0.3	-0.4	0.1	0.5	-0.9	0.5
Qualifications: A levels/AS levels or equivalent	0.1	0.2	0.5	0.4	0.2	-0.6	-0.1	-0.5	0.6	-0.1	-0.2	0.6	0.7
Emphysema/chronic bronchitis	0.1	0.1	0.4	-0.1	-0.1	0.2	0.7	0.4	0.3	-0.2	0.1	0.6	-0.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.1	0.1	0.3	-0.1	-0.3	-0.2	-0.2	0.1	0.2	-0.0	-0.3	-0.2	0.5
Forced expiratory volume in 1-second (FEV1), predicted	0.1	0.2	0.9	0.1	0.1	-0.5	-0.4	-1.0	-0.0	0.5	0.3	-0.8	0.3
Number of self-reported non-cancer illnesses	0.1	0.2	1.2	-0.2	0.0	-0.5	0.5	-0.5	-0.1	0.2	1.1	0.2	0.6
Tanning	0.0	0.6	1.0	1.0	0.6	0.6	0.7	1.0	1.0	0.9	0.4	-0.8	0.5

Hub : Genes

LTBP3

Models

Trait associations