[Hub]/) : Traits : Leg fat mass (left) : ← →

chr10:117,894,117-119,582,073

Best TWAS P=1.57e-12 · Best GWAS P=7.07e-13 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
2	GTEx	Artery Tibial	KIAA1598	0.07	0.02	lasso	2	0.02	5.1e-03	6.7	7.1	1.6e-12	0.96	0.01	0.98	TRUE
15	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	KIAA1598	0.02	0.03	enet	8	0.04	2.4e-05	6.7	6.9	5.6e-12	0.95	0.02	0.98	FALSE
12	YFS	Blood	KIAA1598	0.39	0.64	enet	21	0.64	1.0e-279	6.7	6.9	6.9e-12	0.97	0.03	0.97	FALSE
16	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	KIAA1598	0.04	0.04	enet	6	0.06	2.1e-07	6.8	6.8	8.6e-12	0.93	0.03	0.97	FALSE
5	GTEx	Lung	KIAA1598	0.10	0.10	lasso	6	0.09	1.2e-07	6.7	6.8	1.1e-11	0.97	0.02	0.98	FALSE
7	GTEx	Thyroid	KIAA1598	0.08	0.07	lasso	1	0.06	4.1e-05	6.8	-6.8	1.1e-11	-0.97	0.01	0.99	FALSE
8	GTEx	Whole Blood	KIAA1598	0.27	0.22	lasso	3	0.21	5.7e-19	6.7	6.8	1.3e-11	0.97	0.02	0.98	FALSE
11	NTR	Blood	KIAA1598	0.12	0.20	lasso	4	0.19	3.3e-59	6.7	6.7	1.8e-11	0.98	0.04	0.96	FALSE
9	GTEx	Whole Blood	ENO4	0.17	0.09	lasso	3	0.11	5.3e-10	6.7	6.7	2.5e-11	0.92	0.01	0.99	FALSE
4	GTEx	Colon Transverse	RP11-539I5.1	0.12	0.05	lasso	2	0.04	5.8e-03	7.2	6.6	3.8e-11	0.96	0.01	0.99	FALSE
10	METSIM	Adipose	KIAA1598	0.07	0.11	lasso	8	0.10	2.0e-14	6.7	6.6	5.2e-11	0.96	0.02	0.98	FALSE
13	The Cancer Genome Atlas	Breast Invasive Carcinoma	KIAA1598	0.01	0.01	blup	82	0.01	4.8e-03	7.2	6.6	5.7e-11	0.91	0.03	0.91	FALSE
14	The Cancer Genome Atlas	Colon Adenocarcinoma	KIAA1598	0.13	0.07	lasso	6	0.06	3.7e-04	6.5	6.5	6.9e-11	0.79	0.04	0.92	FALSE
17	The Cancer Genome Atlas	Stomach Adenocarcinoma	KIAA1598	0.05	0.03	enet	5	0.02	2.2e-02	6.1	6.3	2.8e-10	0.80	0.03	0.57	FALSE
1	GTEx	Artery Aorta	KIAA1598	0.28	0.05	lasso	6	0.04	2.0e-03	7.2	6.1	1.4e-09	0.81	0.01	0.98	FALSE
3	GTEx	Cells Transformed fibroblasts	KIAA1598	0.20	0.21	lasso	3	0.22	4.4e-16	6.1	6.0	2.0e-09	0.85	0.16	0.84	FALSE
6	GTEx	Spleen	KIAA1598	0.27	-0.01	enet	18	0.00	3.8e-01	7.1	5.4	5.9e-08	0.78	0.04	0.61	FALSE