TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Leg fat mass (left)
:
←
→
chr11:7,714,238-9,408,426
Best TWAS P=3.46e-08 · Best GWAS P=2.16e-11 conditioned to 0.000151
7.8M
8M
8.2M
8.4M
8.6M
8.8M
9M
9.2M
9.4M
0
2
4
6
8
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
CommonMind
Brain Pre-frontal Cortex
STK33
0.18
0.18
lasso
9
0.20
3.8e-24
-4.8
5.5
3.5e-08
-0.83
0.90
0.10
TRUE
5
The Cancer Genome Atlas
Thyroid Carcinoma
STK33
0.14
0.08
lasso
6
0.10
1.0e-09
-5.1
5.5
3.6e-08
-0.66
0.89
0.11
FALSE
2
GTEx
Brain Caudate basal ganglia
RP11-152H18.3
0.23
0.01
enet
1
0.06
1.1e-02
-5.1
-5.2
2.7e-07
0.69
0.04
0.70
FALSE
3
The Cancer Genome Atlas
Kidney Renal Clear Cell Carcinoma
STK33
0.05
0.03
lasso
2
0.03
2.5e-04
-5.3
5.1
2.7e-07
-0.53
0.45
0.16
FALSE
4
The Cancer Genome Atlas
Testicular Germ Cell Tumors
ST5
0.41
0.02
blup
128
0.13
2.3e-05
3.2
-5.1
2.9e-07
0.58
0.03
0.61
FALSE