[Hub]/) : Traits : Leg fat mass (left) : ← →

chr12:109,591,369-111,699,146

Best TWAS P=4.48e-11 · Best GWAS P=1.62e-10 conditioned to 0.641

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
8	GTEx	Muscle Skeletal	IFT81	0.08	0.08	lasso	5	0.07	1.7e-07	6.3	6.6	4.5e-11	0.95	0.02	0.98	TRUE
3	GTEx	Cells EBV-transformed lymphocytes	ARPC3	0.13	0.09	lasso	4	0.04	2.0e-02	6.3	-6.4	2.0e-10	-0.98	0.02	0.88	FALSE
20	The Cancer Genome Atlas	Thyroid Carcinoma	RAD9B	0.10	0.06	enet	5	0.06	1.2e-06	6.2	6.3	3.9e-10	0.99	0.01	0.99	FALSE
11	GTEx	Skin Sun Exposed Lower leg	ARPC3	0.13	0.15	lasso	3	0.15	1.9e-12	6.2	-6.2	4.2e-10	-0.99	0.02	0.98	FALSE
10	GTEx	Skin Not Sun Exposed Suprapubic	VPS29	0.06	0.01	lasso	3	0.01	6.9e-02	6.4	6.2	4.5e-10	0.93	0.03	0.76	FALSE
13	GTEx	Testis	ARPC3	0.16	0.16	lasso	3	0.14	7.5e-07	6.2	-6.2	4.8e-10	-0.99	0.02	0.98	FALSE
12	GTEx	Spleen	VPS29	0.24	0.01	enet	14	0.04	2.9e-02	4.4	6.0	2.0e-09	0.87	0.02	0.74	FALSE
19	The Cancer Genome Atlas	Lung Adenocarcinoma	RAD9B	0.04	0.03	lasso	5	0.01	7.0e-03	6.2	6.0	2.3e-09	0.97	0.01	0.99	FALSE
6	GTEx	Muscle Skeletal	ARPC3	0.14	0.11	enet	23	0.10	2.2e-10	6.3	-5.9	3.5e-09	-0.95	0.02	0.98	FALSE
1	GTEx	Adrenal Gland	PPTC7	0.13	-0.01	lasso	6	0.00	3.4e-01	6.3	5.9	3.6e-09	0.81	0.03	0.36	FALSE
14	NTR	Blood	GPN3	0.03	0.01	blup	236	0.02	2.7e-06	4.3	-5.8	7.9e-09	-0.86	0.03	0.97	FALSE
9	GTEx	Muscle Skeletal	ANAPC7	0.08	0.01	lasso	3	0.00	1.1e-01	4.3	5.6	1.9e-08	0.87	0.04	0.75	FALSE
5	GTEx	Esophagus Muscularis	IFT81	0.26	0.24	lasso	5	0.26	6.7e-16	5.0	5.6	2.5e-08	0.96	0.02	0.98	FALSE
7	GTEx	Muscle Skeletal	VPS29	0.06	0.06	lasso	3	0.05	4.3e-06	5.8	5.5	3.2e-08	0.69	0.37	0.62	FALSE
2	GTEx	Artery Tibial	VPS29	0.05	0.03	lasso	3	0.02	5.9e-03	5.8	5.5	3.6e-08	0.68	0.11	0.58	FALSE
18	The Cancer Genome Atlas	Brain Lower Grade Glioma	VPS29	0.06	0.06	enet	7	0.06	2.1e-07	4.8	5.5	3.7e-08	0.77	0.12	0.88	FALSE
16	The Cancer Genome Atlas	Breast Invasive Carcinoma	VPS29	0.02	0.02	lasso	5	0.03	4.6e-06	4.8	5.5	3.9e-08	0.80	0.02	0.97	FALSE
4	GTEx	Cells Transformed fibroblasts	VPS29	0.09	0.13	lasso	3	0.13	9.8e-10	5.8	5.3	9.9e-08	0.64	0.41	0.59	FALSE
17	The Cancer Genome Atlas	Brain Lower Grade Glioma	RAD9B	0.04	0.02	blup	29	0.03	4.9e-04	6.3	5.3	1.3e-07	0.71	0.01	0.94	FALSE
15	YFS	Blood	GLTP	0.05	0.01	enet	14	0.04	1.5e-13	5.0	5.2	1.9e-07	0.77	0.01	0.99	FALSE