TWAS
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Traits
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Traits
:
Leg fat mass (left)
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chr13:27,315,078-28,704,081
Best TWAS P=1.71e-08 · Best GWAS P=8.7e-11 conditioned to 0.034
27.4M
27.6M
27.8M
28M
28.2M
28.4M
28.6M
0
2
4
6
8
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
The Cancer Genome Atlas
Brain Lower Grade Glioma
GTF3A
0.03
0.00
enet
8
0.01
0.0228
1.5
5.6
1.7e-08
-0.63
0.01
0.84
TRUE
1
GTEx
Nerve Tibial
AL137059.1
0.10
0.02
lasso
3
0.03
0.0029
4.1
-5.6
2.6e-08
0.71
0.02
0.94
TRUE