Best TWAS P=1.32e-10 · Best GWAS P=1.35e-13 conditioned to 5.13e-14
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Frontal Cortex BA9 | TEX29 | 0.45 | 0.10 | lasso | 8 | 0.24 | 4.2e-07 | -4.9 | -6.4 | 1.3e-10 | -0.01 | 0.11 | 0.12 | TRUE |
| 2 | GTEx | Muscle Skeletal | ARHGEF7 | 0.14 | 0.05 | enet | 49 | 0.06 | 1.3e-06 | -4.6 | 5.1 | 2.7e-07 | -0.03 | 0.87 | 0.01 | FALSE |
| 3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | ARHGEF7 | 0.09 | 0.07 | blup | 142 | 0.08 | 3.1e-09 | -4.9 | 6.2 | 6.3e-10 | -0.04 | 1.00 | 0.00 | TRUE |