Best TWAS P=1.8e-09 · Best GWAS P=7.9e-14 conditioned to 5.76e-06
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Nerve Tibial | NEO1 | 0.07 | 0.09 | lasso | 2 | 0.09 | 3.9e-07 | -5.3 | -5.4 | 6.9e-08 | 0.45 | 0.93 | 0.02 | FALSE |
| 2 | GTEx | Pituitary | BBS4 | 0.27 | 0.02 | enet | 21 | 0.05 | 2.1e-02 | -5.1 | -5.5 | 3.7e-08 | 0.69 | 0.05 | 0.48 | FALSE |
| 3 | GTEx | Testis | ADPGK-AS1 | 0.17 | 0.05 | lasso | 4 | 0.03 | 1.3e-02 | -4.3 | 6.0 | 1.8e-09 | -0.72 | 0.02 | 0.89 | TRUE |