Hub : Genes

BBS4

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Cells Transformed fibroblasts	0.0850	0.0360	1.5e-03	0.098	NA	0.086	NA	0.102	9.0e-08	NA	5.2e-07	NA	4.7e-08
2	GTEx	Pituitary	0.2660	0.1200	4.9e-03	0.022	NA	0.051	NA	0.023	9.3e-02	NA	2.1e-02	NA	8.6e-02
3	GTEx	Uterus	0.3230	0.1230	9.7e-03	0.048	NA	0.057	NA	0.061	3.9e-02	NA	2.8e-02	NA	2.3e-02
4	METSIM	Adipose	0.0227	0.0140	2.4e-02	0.029	0.011	0.023	0.015	0.026	2.8e-05	6.5e-03	2.0e-04	2.1e-03	7.7e-05
5	YFS	Blood	0.0660	0.0194	1.4e-09	0.049	0.037	0.046	0.053	0.052	9.2e-16	3.4e-12	6.3e-15	5.8e-17	1.1e-16
6	TCGA	Head and Neck Squamous Cell Carcinoma	0.0515	0.0312	9.0e-04	0.043	0.029	0.026	NA	0.036	1.3e-05	2.9e-04	5.9e-04	NA	5.4e-05
7	TCGA	Brain Lower Grade Glioma	0.0411	0.0257	1.3e-03	0.010	0.021	0.011	NA	0.011	2.0e-02	1.8e-03	1.6e-02	NA	1.6e-02
8	TCGA	Pheochromocytoma and Paraganglioma	0.0870	0.0530	2.3e-03	0.026	0.041	0.044	NA	0.029	3.2e-02	9.3e-03	7.7e-03	NA	2.6e-02
9	TCGA	Prostate Adenocarcinoma	0.0322	0.0244	6.0e-03	0.002	0.008	0.009	NA	0.007	1.9e-01	4.8e-02	3.7e-02	NA	6.0e-02

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Bipolar Disorder (2018)	0.2	0.4	1.1	0.6	-0.3	-0.4	0.9	0.7	0.2	1.0	-0.5	0.1
Bipolar Disorder or Schizophrenia	0.0	0.1	0.7	-0.1	0.0	0.1	0.8	-0.1	-0.3	0.1	-0.0	-0.4
Depressed Affect (Nagel 2018)	0.4	0.8	1.5	0.5	-1.1	1.1	0.3	0.7	0.9	0.3	1.2	1.1
Depression (Nagel 2018)	0.6	1.0	1.9	-1.2	0.6	0.9	-1.0	-1.0	-1.0	-1.4	0.8	-0.8
Intelligence (Savage-Jansen 2018)	0.1	0.3	1.2	-0.7	0.6	0.5	-0.2	-0.0	0.1	-0.6	-1.1	-0.5
Neuroticism (Nagel 2018)	0.2	0.5	1.5	0.5	-0.4	0.9	0.3	0.6	1.2	0.1	0.8	1.0
Schizophrenia (2018)	0.1	0.3	0.6	-0.6	0.3	0.5	0.3	-0.8	-0.6	-0.7	0.4	-0.6
Schizophrenia vs Biploar Disorder	0.2	0.2	0.5	0.5	0.7	0.5	0.7	0.4	0.2	0.0	-0.4	-0.0
Worry (Nagel 2018)	0.2	0.4	2.2	0.6	-0.0	-0.3	0.2	0.3	0.7	-0.0	1.5	0.8
Alzheimer’s Disease (in mother)	0.5	0.6	3.6	-0.7	-0.6	0.1	0.5	-0.6	0.4	-0.5	-1.9	0.4
Alzheimer’s Disease (in father)	1.4	1.5	3.9	1.5	-2.0	0.0	0.2	1.0	1.3	1.1	0.7	1.7
Alzheimer’s Disease (including proxy)	0.6	0.8	2.5	0.7	-1.3	0.0	0.7	0.3	1.3	0.6	-0.6	1.6
Crohns Disease (2017)	0.8	1.7	3.9	0.4	-0.3	-0.5	-2.0	-1.9	2.0	0.7	0.5	1.6
Irritable Bowel Disease (IBD)	0.2	0.6	1.6	0.1	0.5	-0.0	-1.1	-1.2	1.3	0.2	-0.1	0.7
Ulcerative Colitis (UC)	0.1	0.2	1.2	-0.2	1.1	0.5	0.1	-0.2	0.2	-0.3	-0.4	-0.5
Major Depression (MDD)	2.8	3.4	6.6	2.5	-2.6	-0.0	0.7	1.0	2.2	2.1	1.0	2.5
Reaction Time	1.4	2.7	6.8	2.2	-1.7	-0.6	-0.5	0.7	2.1	2.6	0.2	2.0
Verbal and Numeric Reasoning (VNR)	0.5	1.1	3.1	-1.3	0.4	0.3	-1.7	-1.7	-0.6	-0.6	-0.1	-1.2
Breast Cancer	0.3	0.8	1.8	1.2	-0.7	0.1	-0.3	0.1	1.2	1.3	0.5	1.2
Ovarian Cancer	1.1	1.5	3.2	0.3	0.7	1.4	1.7	1.8	-1.3	-0.7	1.4	-0.6
Prostate Cancer	0.3	0.4	3.1	-0.1	0.1	-1.8	-0.5	-0.0	-0.0	0.2	-0.2	-0.2
Age at First Birth	0.5	0.7	1.9	-0.4	1.4	0.9	0.6	0.5	-0.8	-1.1	-0.8	-0.5
Bipolar Disorder (2011)	1.2	1.1	4.1	0.8	-0.6	-2.0	-0.7	-0.5	1.1	1.5	0.6	0.5
Body Mass Index (BMI) (2010)	2.8	3.8	8.0	2.4	-2.8	-0.1	1.3	1.5	1.8	2.5	0.7	2.5
Coronary Artery Disease (CAD)	1.0	1.1	3.8	0.8	0.2	-1.3	1.4	0.8	1.2	-0.3	0.4	1.9
Crohns Disease (2012)	0.3	0.5	1.4	0.2	0.2	-0.2	-1.2	-0.9	0.9	0.5	0.5	0.6
Mean Putamen Volume	0.6	0.7	4.8	-0.6	0.1	-2.2	-0.3	-0.7	-0.5	-0.7	0.1	-0.2
Fasting Glucose	1.3	1.6	3.5	-1.2	1.9	-1.3	0.0	-0.2	-1.3	-1.9	-0.3	-1.5
HbA1C	0.5	0.6	2.3	0.5	-0.5	0.5	0.8	1.1	0.1	0.0	1.5	0.3
HDL Cholesterol	0.9	1.5	4.8	-1.0	1.8	0.6	0.1	0.3	-1.5	-2.2	0.2	-1.3
LDL Cholesterol	0.6	0.9	3.8	-0.7	-0.4	-0.1	-1.8	-2.0	0.2	0.3	-0.3	-0.2
Lupus	0.1	0.2	0.7	-0.2	-0.0	0.1	-0.9	-0.5	-0.5	-0.1	0.4	-0.7
Neuroticism (2016)	0.2	0.3	0.9	0.4	-0.7	-0.2	-0.1	-0.0	0.7	0.4	1.0	0.4
Primary Biliary Cirrhosis	0.4	0.6	1.7	-0.7	1.3	-0.6	-0.4	-1.0	-0.3	-0.1	-0.8	-0.9
Rheumatoid Arthritis	0.1	0.2	0.8	-0.3	0.1	-0.2	-0.5	-0.2	0.2	0.3	-0.9	-0.4
Schizophrenia (2014)	0.1	0.2	0.5	0.2	0.0	0.5	0.4	-0.5	0.6	0.5	0.7	0.3
Triglycerides	3.5	5.7	14.7	2.1	-3.8	-2.4	2.5	1.5	1.9	2.4	-0.3	2.8
Type 2 Diabetes (T2D) (2012)	0.7	0.8	2.1	0.2	-1.5	0.4	1.4	1.3	-0.7	0.1	0.5	-0.1
Ulcerative Colitis	0.3	0.4	2.2	-0.1	1.5	-0.1	0.5	0.1	0.4	-0.1	-0.8	-0.4
Blood Eosinophil Count	0.1	0.5	2.5	0.5	-0.5	-0.1	1.6	0.5	-0.8	-0.3	0.8	-0.0
Blood Platelet Count	0.6	6.4	16.0	2.9	-1.3	4.0	2.4	3.7	1.5	3.0	0.0	0.6
Blood Red Count	2.7	25.8	54.5	4.9	-6.3	-3.1	4.5	2.5	6.8	5.5	-0.2	7.4
Blood White Count	0.3	1.9	6.5	-0.7	-0.6	-2.2	-0.6	-0.8	-1.6	-1.2	2.5	-0.5
Heel T-Score	0.1	0.8	3.2	0.0	-0.9	-0.6	0.1	0.5	1.4	0.4	-0.5	1.8
BMI	2.0	11.4	32.0	3.4	-5.7	-2.8	2.4	1.1	1.5	2.6	4.0	4.5
Height	0.8	15.0	35.5	-4.1	5.0	-0.6	-3.5	-2.8	-4.9	-3.4	-1.6	-6.0
Waist Hip Ratio (WHR)	0.5	2.4	4.0	0.8	-1.8	1.4	1.4	1.5	2.0	1.8	-1.8	1.2
Systolic Blood Pressure	0.2	1.2	4.5	-1.2	0.7	-2.1	0.1	-0.4	0.4	-0.1	-2.1	-0.5
Smoking Status	0.4	0.9	3.2	0.4	-1.0	1.3	1.8	1.3	-0.4	-0.2	0.6	0.3
Allergy or Eczema	0.2	0.5	2.3	-0.5	1.5	-0.1	0.4	-0.2	0.3	-0.8	-0.8	0.2
Cardiovascular Disease	1.4	4.7	12.9	1.9	-3.6	-1.4	1.6	0.6	2.5	2.2	-0.2	3.1
Hypothyroidism (self reported)	1.7	3.9	8.8	1.9	-1.8	-0.7	2.0	1.6	2.6	2.1	-1.0	3.0
Respiratory disease	0.3	0.7	3.8	0.5	0.9	0.5	-0.8	-0.9	-0.3	0.2	2.0	0.1
Type 2 Diabetes (T2D) (2018)	0.4	0.7	1.7	0.2	-1.2	1.2	0.9	1.3	-0.7	0.1	-0.2	-0.7
Lung FEV1/FVC ratio	0.3	1.4	5.2	-0.4	-2.3	1.6	-0.5	0.6	1.4	-0.2	-0.6	1.3
Lung FVC	1.0	5.0	11.9	-2.5	3.5	1.3	-1.8	-0.7	-1.7	-2.0	-1.9	-3.4
Neuroticism	0.5	1.1	3.0	0.6	-1.7	0.7	0.3	0.5	1.7	0.7	-0.3	1.5
Chronotype (morning person)	1.5	3.6	8.8	1.8	-2.3	-1.3	3.0	0.9	1.7	1.8	0.6	2.5
Hair Pigment	0.2	5.3	9.6	-3.1	2.9	-1.4	-2.4	-3.1	-1.3	-2.3	-1.7	-1.8
Tanning	0.1	1.1	2.5	-1.3	-0.3	0.5	-1.2	-1.6	-1.2	-1.2	-0.5	-0.9
Hand grip strength (left)	1.4	3.7	10.5	-2.0	2.6	-0.7	0.4	0.3	-2.3	-2.1	-1.4	-3.2
Number of treatments/medications taken	0.8	1.5	4.6	0.3	-2.0	-1.3	2.1	0.8	0.3	0.2	-0.9	1.2
Average weekly spirits intake	0.6	0.8	1.6	-1.3	0.6	-1.0	-0.3	-0.5	-0.9	-1.0	-0.9	-1.0
Sensitivity / hurt feelings	0.4	0.6	1.6	-0.4	-1.1	1.1	-1.3	-1.0	0.3	-0.3	-0.3	0.2
Frequency of depressed mood in last 2 weeks	0.4	0.6	2.8	-0.1	0.5	0.3	0.4	0.3	-1.1	-0.7	1.7	-0.5
Hearing difficulty/problems: Yes	3.2	4.9	10.0	2.9	-2.4	0.3	1.7	1.3	2.6	2.9	0.9	3.2
Relative age of first facial hair	0.2	0.4	1.8	-0.2	0.2	-0.3	0.1	-0.0	-1.3	0.5	0.1	-1.3
Other serious medical condition/disability diagnosed by doctor	0.3	0.3	0.6	-0.0	0.4	-0.7	0.7	-0.2	0.7	0.7	-0.7	0.5
Ever used hormone-replacement therapy (HRT)	0.8	1.0	3.4	0.1	-0.9	1.8	1.6	0.9	-0.5	0.2	-1.1	-0.0
Ever had hysterectomy (womb removed)	0.7	0.8	3.7	0.2	0.5	0.3	1.9	1.1	0.3	0.3	-1.2	0.6
Systolic blood pressure, automated reading	0.2	0.7	3.0	-0.9	1.0	-1.1	0.2	-0.6	0.4	-0.1	-1.7	-0.1
Eye problems/disorders: Diabetes related eye disease	0.4	0.4	1.6	0.4	-1.3	-0.5	0.7	0.5	0.0	0.7	0.2	0.4
Angina	1.5	2.0	5.2	1.6	-1.3	-1.1	-0.1	-0.1	1.9	1.2	1.5	2.3
Medication for hormone replacement therapy	0.4	0.5	2.2	0.4	0.7	-1.5	0.3	0.0	-0.2	1.0	-0.4	-0.3
Vitamin and mineral supplements	1.9	2.6	7.6	1.3	-2.7	-0.8	-0.9	-0.7	1.5	1.8	1.6	2.0
Supplements: Zinc	1.8	1.9	4.3	2.1	-0.1	0.5	1.7	1.9	1.5	1.4	0.9	1.2
Medication: Co-codamol	0.5	0.6	2.5	0.4	-1.6	0.5	-0.7	-0.5	-0.2	0.5	1.2	0.2
Medication: Metformin	1.1	1.6	4.9	1.5	-1.3	0.4	2.0	2.2	0.1	0.8	0.6	0.6
Diabetes (father)	1.0	1.2	3.0	1.7	-0.6	1.1	0.3	0.5	1.1	1.0	1.3	1.4
Diabetes (mother)	0.1	0.1	0.8	0.2	-0.3	-0.9	-0.2	-0.0	0.2	0.3	0.1	0.2
Severe depression (siblings)	0.7	0.7	5.1	0.2	0.5	2.3	-0.5	0.5	-0.3	-0.1	0.8	-0.2
Pack years adult smoking proportion	0.3	0.4	1.4	0.4	-1.2	0.5	0.4	0.1	0.6	0.7	-0.1	0.8
Impedance of leg (right)	0.1	0.5	1.7	0.3	-0.2	0.8	-1.0	0.2	0.0	0.9	-0.5	-1.3
Leg fat-free mass (left)	0.3	1.3	5.7	-0.0	-1.1	-2.4	-0.2	-0.9	-1.2	-0.5	1.5	0.3
Trunk fat percentage	2.2	8.7	35.4	3.0	-6.0	-1.9	0.9	0.2	1.2	3.0	2.9	3.3
Hand grip strength (right)	1.6	4.3	10.5	-2.3	2.4	-1.1	-0.8	-0.9	-2.6	-2.6	-1.1	-3.2
Townsend deprivation index at recruitment	0.4	0.6	1.2	0.7	-0.9	-1.0	0.3	0.5	1.1	1.1	-0.0	0.6
Current tobacco smoking	0.5	0.9	2.5	-0.7	0.3	-0.1	-0.3	-0.7	-1.6	-0.8	1.3	-1.4
Average weekly fortified wine intake	2.3	2.7	11.2	-1.4	3.3	1.2	-1.3	-0.7	-0.6	-1.2	-1.8	-1.5
Maternal smoking around birth	0.2	0.2	0.6	-0.4	-0.2	-0.5	-0.6	-0.4	-0.6	-0.4	0.8	-0.4
Fed-up feelings	0.1	0.3	1.5	-0.0	-0.2	1.2	-0.6	-0.0	0.4	0.1	0.6	-0.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.9	1.2	2.6	-1.1	0.8	0.2	-1.1	-0.6	-1.6	-1.2	0.8	-1.6
Relative age voice broke	0.6	0.9	3.1	0.1	0.6	-0.2	0.8	0.9	-1.8	-0.4	0.4	-1.6
Taking other prescription medications	0.4	0.7	2.2	0.3	-1.2	0.6	1.5	0.6	0.1	0.2	-0.9	0.7
Age when periods started (menarche)	0.3	0.8	2.2	0.5	0.8	-0.1	0.2	0.8	-1.5	0.4	1.2	-1.3
Bilateral oophorectomy (both ovaries removed)	0.7	0.8	1.6	1.0	-1.3	1.2	0.8	0.8	0.2	1.1	0.2	0.4
Heel bone mineral density (BMD) T-score, automated (left)	0.5	1.1	3.8	-1.4	1.3	-0.1	0.0	0.2	-0.2	-1.5	-1.9	-0.2
Tinnitus: Yes, but not now, but have in the past	0.4	0.4	1.0	0.2	-0.1	-0.4	1.0	1.0	-0.9	-0.4	0.2	-0.4
Qualifications: CSEs or equivalent	0.3	0.5	1.6	1.2	-0.5	0.2	0.1	0.3	0.8	1.0	0.7	0.3
Serious illness, injury or assault to yourself	0.9	1.1	4.5	-0.1	0.9	-2.1	1.2	0.4	0.8	-0.0	-1.3	0.7
High blood pressure	0.6	1.7	4.9	0.2	-1.7	-0.7	1.0	-0.6	1.8	0.7	-1.4	2.2
Hayfever, allergic rhinitis or eczema	0.1	0.2	0.4	-0.1	0.3	0.5	0.4	0.1	0.6	-0.6	-0.2	0.4
Multivitamins +/- minerals	2.0	2.5	3.9	-1.0	1.5	2.0	1.7	1.4	-1.7	-1.8	-1.0	-2.0
Stomach or abdominal pain in last month	0.5	0.6	2.1	0.1	-1.0	-0.7	-0.6	-0.6	-0.9	-0.1	1.4	-0.5
Supplements: Glucosamine	1.3	1.6	4.8	-1.0	0.8	0.8	0.4	0.3	-2.2	-1.8	-0.1	-2.0
Diverticular disease/diverticulitis (self-reported)	1.7	2.0	4.8	1.7	-2.1	-0.2	-0.0	-0.2	1.7	2.2	0.1	1.8
Medication: Atenolol	1.1	1.4	4.1	1.2	-1.5	-0.8	-0.0	-0.3	1.8	1.0	-0.2	2.0
Medication: Levothyroxine sodium	0.4	0.7	3.3	0.3	-0.6	-1.8	0.9	0.0	0.5	0.7	0.5	1.0
Sitting height	0.3	2.4	6.7	-1.8	2.6	-1.1	-0.4	-1.1	-1.3	-1.8	-1.0	-1.9
Chronic bronchitis/emphysema (father)	1.0	1.1	4.6	-1.0	1.5	-1.1	0.5	-0.3	-0.3	-0.6	-2.2	-0.4
High blood pressure (mother)	0.9	1.3	3.9	1.5	0.4	-0.1	0.6	0.6	2.0	1.5	-0.5	1.4
Body mass index (BMI)	1.9	8.1	25.3	2.9	-5.0	-2.1	1.4	0.7	1.4	2.4	3.1	3.8
Impedance of leg (left)	0.1	0.6	3.2	0.1	-0.1	0.8	-0.9	0.4	-0.6	0.6	-0.2	-1.8
Leg predicted mass (left)	0.2	1.3	5.8	-0.0	-1.1	-2.4	-0.1	-0.9	-1.2	-0.4	1.5	0.3
Trunk fat mass	1.6	7.1	28.2	2.6	-5.3	-2.1	0.7	-0.1	0.7	2.4	3.0	2.9
Waist circumference	2.0	7.4	26.8	2.5	-5.2	-2.8	0.9	0.3	1.2	2.4	2.6	3.3
Number of incorrect matches in round	0.5	0.8	3.8	-0.0	-1.9	0.3	-0.7	-0.9	0.8	0.4	0.3	0.9
Past tobacco smoking	1.2	2.1	4.8	-1.9	1.4	-0.0	-1.5	-1.4	-1.5	-1.2	-1.1	-2.2
Alcohol usually taken with meals	0.6	1.0	3.6	-1.2	1.0	0.2	0.0	0.2	0.0	-1.7	-1.9	0.3
Nervous feelings	0.9	1.6	4.3	1.1	0.3	2.1	-0.8	-0.1	1.6	0.5	2.0	1.1
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.6	4.1	-0.0	-0.0	-0.5	-0.4	-0.2	-0.1	-0.8	2.0	0.6
Hearing difficulty/problems with background noise	1.4	2.3	6.5	1.7	-2.6	-0.4	1.8	1.3	0.8	1.1	0.8	1.9
Hair/balding pattern: Pattern 2	0.6	0.8	1.7	-0.8	-0.5	1.1	1.1	1.1	-0.6	-1.3	-0.4	-0.5
Had menopause	0.6	0.7	1.7	-1.1	1.0	-0.0	0.5	-0.2	-1.3	-1.1	-0.9	-0.7
Had other major operations	0.8	0.9	3.7	0.9	-1.1	-0.4	0.2	-0.4	0.3	0.1	1.9	1.5
Forced vital capacity (FVC)	2.3	8.9	22.1	-3.4	4.1	-0.6	-2.2	-1.1	-3.1	-2.9	-2.2	-4.7
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.8	3.5	-1.0	0.6	0.2	-0.1	0.2	0.3	-1.2	-1.9	0.4
Ever unenthusiastic/disinterested for a whole week	1.2	1.4	5.4	-0.1	-0.6	-0.1	-2.3	-1.9	0.0	-0.1	1.8	0.2
Qualifications: None of the above	0.6	1.3	4.0	0.9	-1.6	-0.7	1.3	0.5	0.2	0.4	2.0	1.2
Financial difficulties in last 2 years	0.5	0.7	2.1	-0.0	0.5	1.1	-1.4	-0.2	-0.7	-0.5	1.2	-0.7
Mouth/teeth dental problems	2.6	4.0	8.7	-1.7	3.0	1.4	0.6	1.1	-2.3	-2.3	-1.8	-2.7
Heart attack	2.1	2.7	7.2	2.0	-1.3	0.4	2.7	2.3	0.3	0.7	1.9	1.3
Allergy	0.1	0.1	0.3	-0.1	-0.5	-0.5	-0.1	0.5	-0.4	0.0	-0.3	-0.2
Pain all over the body in last month	0.8	0.9	2.0	1.2	-0.8	-1.3	0.2	0.8	0.6	0.5	0.8	1.4
Diabetes (self-reported)	0.4	0.6	1.7	-0.2	-0.4	1.3	0.4	0.9	-1.1	-0.5	0.4	-0.8
Hayfever/allergic rhinitis (self-reported)	1.3	1.7	5.9	-0.1	-0.6	1.7	2.4	2.1	-0.8	-0.3	-0.5	-0.4
Medication: Ramipril	1.6	2.1	10.8	0.8	0.6	0.4	3.3	2.6	-0.2	-0.3	-0.3	0.0
Medication: Simvastatin	0.9	1.3	8.3	0.5	-2.9	-0.0	1.4	0.6	-0.1	0.0	0.5	0.9
Fluid intelligence score	0.3	0.6	2.3	-0.3	0.1	1.0	-1.5	-1.4	0.2	0.3	0.4	-0.2
Illnesses of siblings	2.1	2.9	9.2	-1.1	2.4	0.5	-2.0	-1.2	-2.0	-0.6	0.1	-3.0
Neuroticism score	0.4	0.9	2.7	0.8	-1.6	1.0	0.4	1.0	1.0	0.4	0.7	0.9
Weight	0.8	3.7	12.7	1.6	-3.6	-2.4	0.4	-0.2	-0.1	1.3	2.6	1.9
Impedance of arm (right)	0.2	0.7	1.8	0.3	-0.7	1.3	-0.1	0.4	0.0	1.1	-1.2	-1.1
Arm fat percentage (right)	2.5	9.7	35.9	3.2	-6.0	-1.9	1.1	0.2	1.6	3.1	3.1	3.9
Trunk fat-free mass	0.3	1.6	3.9	-1.2	0.9	-1.8	-0.5	-0.9	-2.0	-1.5	0.7	-1.1
Hip circumference	1.2	5.3	13.2	1.8	-3.6	-3.6	0.0	-0.3	-0.3	1.1	3.5	2.2
Time employed in main current job	1.2	1.4	4.4	-1.0	2.1	-1.6	-0.6	-0.6	-0.9	-1.1	-0.3	-1.3
Alcohol intake versus 10 years previously	0.4	0.6	3.5	-0.5	-1.9	-0.3	-0.3	-0.7	-0.7	-0.3	0.3	-0.2
Father’s age at death	0.4	0.5	1.1	1.1	0.9	1.0	0.3	0.8	0.6	0.3	0.7	0.3
Worrier / anxious feelings	0.4	0.8	2.3	0.6	-0.4	1.4	1.4	1.5	0.5	-0.1	-0.1	0.8
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.3	0.9	-0.1	0.0	-0.7	-0.9	-0.3	-0.1	-0.1	0.9	-0.3
Falls in the last year	0.6	0.7	2.0	0.8	-1.1	-0.4	1.4	0.8	0.6	0.3	0.2	1.3
Hair/balding pattern: Pattern 3	0.5	0.7	2.1	0.5	0.7	-1.2	-1.0	-0.3	-0.5	0.7	1.5	-0.3
Number of live births	0.9	1.3	3.3	-1.3	0.3	-0.0	-1.8	-1.3	-1.1	-1.4	0.3	-1.1
Forced expiratory volume in 1-second (FEV1)	2.0	6.8	15.8	-3.2	3.1	-0.1	-1.9	-0.7	-2.5	-2.8	-2.6	-4.0
Pulse rate	4.6	7.7	31.5	2.3	-5.6	-2.1	1.2	0.8	2.2	2.5	1.5	3.6
Happiness	1.1	1.3	6.0	-0.4	0.7	2.4	0.2	0.9	-1.4	-0.3	0.4	-1.5
Noisy workplace	0.7	0.9	4.2	-0.7	-0.2	-2.0	-0.5	-0.7	-1.0	-0.3	0.3	-1.1
Qualifications: A levels/AS levels or equivalent	1.9	4.2	16.7	-2.8	2.2	-0.3	-0.6	-1.7	-0.3	-1.9	-4.1	-1.4
Serious illness, injury or assault of a close relative in last 2 years	0.7	0.9	2.6	-0.8	1.5	-0.2	0.2	0.6	-0.6	-1.1	-1.6	-0.6
Mouth/teeth dental problems: Dentures	3.9	6.6	16.4	2.4	-4.0	-1.3	0.8	0.1	2.7	2.6	2.6	3.7
Asthma	0.4	0.8	2.6	0.5	1.1	0.5	-1.1	-1.3	0.2	0.3	1.6	0.3
Medication: Ibuprofen (e.g. Nurofen)	1.4	1.8	7.3	0.2	-1.3	-2.7	1.2	0.8	0.8	0.9	-1.7	0.8
Medication: Cholesterol lowering	3.0	4.6	7.8	2.3	-2.8	1.4	2.0	2.0	2.2	2.4	0.3	2.7
Depression (self-reported)	0.5	0.6	1.9	0.2	-0.6	0.1	1.4	1.4	-0.9	-0.3	-0.3	-0.1
Medication: Lansoprazole	0.9	1.1	5.8	0.7	-2.4	-0.8	0.6	0.5	0.2	0.1	0.8	1.0
Prospective memory result	0.1	0.2	0.6	0.1	0.2	-0.4	-0.3	-0.8	0.3	0.5	0.2	0.6
Lung cancer (father)	2.5	2.9	8.4	2.2	-1.2	-0.3	-0.4	-0.5	2.5	2.9	0.8	2.0
Illnesses of mother	1.6	2.0	6.2	-1.4	0.3	1.2	0.4	0.6	-2.5	-1.6	-0.1	-2.3
Forced expiratory volume in 1-second (FEV1), Best measure	2.5	7.8	17.8	-3.6	3.4	-0.9	-2.0	-1.1	-2.6	-2.9	-2.7	-4.2
Pulse wave Arterial Stiffness index	0.6	0.7	4.2	0.6	-0.1	-1.2	0.2	0.2	0.0	0.4	2.1	0.5
Impedance of arm (left)	0.2	0.7	2.2	0.8	-1.3	0.9	-0.0	0.5	0.6	1.5	-0.7	-0.5
Arm fat mass (right)	1.7	7.1	26.1	2.6	-5.1	-2.1	0.8	0.0	0.9	2.4	3.2	3.2
Trunk predicted mass	0.2	1.3	3.2	-1.1	0.8	-1.7	-0.4	-0.8	-1.8	-1.4	0.6	-0.9
Standing height	0.6	6.0	14.7	-2.6	2.7	-1.0	-2.0	-1.8	-3.2	-2.3	-1.0	-3.8
Length of working week for main job	1.3	1.4	3.1	1.3	-0.6	-0.4	1.2	1.3	1.4	1.8	0.1	1.5
Exposure to tobacco smoke at home	1.8	2.0	4.0	-0.7	0.7	-2.0	-1.8	-1.5	-1.5	-0.7	1.6	-1.5
Breastfed as a baby	2.4	3.0	7.2	-2.0	1.2	0.2	1.6	0.8	-1.4	-2.6	-2.7	-1.4
Tense / ‘highly strung’	0.3	0.5	1.7	-0.3	0.1	-0.9	-0.1	-0.3	0.4	-1.0	1.3	0.5
Seen doctor (GP) for nerves, anxiety, tension or depression	0.1	0.2	0.7	-0.1	0.0	-0.1	-0.3	-0.5	0.6	-0.3	0.1	0.8
Hair/balding pattern: Pattern 4	0.9	2.1	5.1	2.3	-1.5	-0.7	1.5	1.5	0.8	1.5	1.0	1.5
Birth weight of first child	0.9	1.6	7.0	-1.4	1.5	0.8	0.8	0.2	0.4	-1.5	-2.6	0.0
Peak expiratory flow (PEF)	0.9	2.1	4.1	-2.0	1.5	-0.6	-0.6	-0.3	-1.0	-1.9	-2.0	-1.8
Pulse wave reflection index	1.2	1.5	4.1	0.4	2.0	-0.0	1.9	1.7	-0.9	-0.3	0.4	-1.2
Ever highly irritable/argumentative for 2 days	0.6	0.7	1.7	-0.5	-0.1	-0.8	-1.2	-1.3	-0.6	-0.8	1.1	-0.3
Loud music exposure frequency	1.0	1.1	2.6	-1.1	0.6	-1.4	1.0	0.6	-1.0	-1.6	-0.9	-0.9
Qualifications: O levels/GCSEs or equivalent	0.9	1.4	4.4	-1.1	0.9	1.0	-1.7	-1.2	0.7	-0.2	-2.1	-0.4
Mouth/teeth dental problems: Bleeding gums	1.1	1.5	5.3	-1.1	1.4	-0.4	-2.3	-2.1	-0.1	-0.4	0.0	-0.4
Blood clot in the leg (DVT)	0.4	0.5	2.6	0.5	0.3	-0.1	0.6	0.4	-0.9	0.4	1.6	-0.5
Medication: Paracetamol	2.7	4.5	11.3	2.1	-3.4	-2.2	1.1	0.3	2.2	2.2	1.2	2.7
Headache pain in last month	4.1	7.0	15.8	2.3	-3.9	-2.3	1.1	-0.1	3.7	2.5	0.4	4.0
Medication for cholesterol, blood pressure or diabetes	2.0	3.3	9.0	-1.6	2.3	-0.1	-1.6	-1.0	-2.5	-1.6	0.7	-3.0
Glaucoma (self-reported)	1.6	1.9	7.2	-2.3	0.3	0.1	0.7	0.2	-1.3	-2.7	-1.2	-1.0
Gout (self-reported)	3.0	4.1	8.0	2.8	-2.2	1.3	0.7	0.9	2.6	2.8	0.9	2.5
Hypothyroidism/myxoedema (self-reported)	1.2	2.3	4.7	1.2	-1.6	-1.6	1.3	0.6	1.8	1.7	-0.7	2.2
Medication: Amlodipine	0.6	0.9	3.5	-1.3	-0.2	-0.3	-0.9	-1.9	-0.7	-1.1	-0.1	-0.1
Medication: Ventolin 100micrograms inhaler	0.5	0.6	2.5	1.2	-0.4	-0.4	0.6	0.4	-0.1	0.7	1.6	0.5
Birth weight	0.7	1.5	3.7	1.1	-1.1	-0.4	1.9	1.3	1.2	0.4	0.5	1.9
Chronic bronchitis/emphysema (mother)	0.9	1.1	3.6	-0.6	0.8	-1.9	-1.4	-1.0	-0.9	-0.5	0.4	-1.1
High blood pressure (siblings)	3.6	5.3	12.1	2.6	-2.9	-0.8	1.9	1.4	2.9	2.0	1.1	3.5
Forced vital capacity (FVC), Best measure	2.9	10.6	25.1	-3.8	4.5	-1.3	-2.3	-1.6	-3.3	-3.1	-2.3	-5.0
Body fat percentage	2.6	10.2	39.3	3.4	-6.3	-1.8	1.0	0.4	1.4	3.2	3.3	3.7
Leg fat percentage (right)	3.2	11.6	40.9	3.7	-6.4	-1.8	0.8	0.4	1.8	3.5	3.6	4.1
Arm fat-free mass (right)	0.2	0.9	4.7	-0.3	-0.5	-2.2	0.1	-0.5	-1.1	-0.7	1.2	0.2
Exposure to tobacco smoke outside home	0.2	0.2	0.7	-0.6	-0.2	0.0	0.3	0.6	-0.4	-0.9	0.1	-0.2
Comparative body size at age 10	1.5	4.2	11.5	1.8	-3.1	-0.9	0.5	-0.2	2.9	1.9	0.7	3.4
Number of full brothers	0.2	0.2	0.5	-0.7	-0.6	0.1	0.7	0.0	-0.1	-0.6	0.1	0.2
Worry too long after embarrassment	0.4	0.7	2.2	0.3	-0.8	1.3	0.2	0.3	1.5	0.1	-1.1	0.6
Seen a psychiatrist for nerves, anxiety, tension or depression	0.1	0.2	0.5	0.2	0.1	-0.7	-0.5	-0.4	0.5	0.2	-0.1	0.6
Wheeze or whistling in the chest in last year	0.7	1.3	4.2	1.8	-0.6	-0.1	0.8	0.6	0.3	1.4	2.1	0.9
Number of children fathered	0.5	0.6	1.1	0.9	-0.4	0.9	1.1	0.8	-0.1	0.5	1.0	0.6
Reason for reducing amount of alcohol drunk: Health precaution	0.8	1.0	4.2	-0.2	-0.2	1.1	-0.9	-0.6	1.2	0.9	-2.0	0.3
Age at first live birth	0.7	1.3	5.0	-0.7	2.2	1.2	0.0	-0.1	-0.0	-0.5	-1.9	-0.6
Pulse wave peak to peak time	0.6	0.7	3.7	-0.4	0.4	1.5	-0.2	-0.0	-0.0	-0.2	-1.9	-0.5
Health satisfaction	1.5	2.0	9.5	1.3	-3.1	-0.1	1.0	0.7	0.3	1.4	1.1	1.4
Shortness of breath walking on level ground	0.3	0.4	2.1	-0.3	-0.6	-1.5	0.4	0.1	-0.7	-0.1	0.1	-0.1
Qualifications: College or University degree	0.4	1.3	4.6	-1.1	2.1	0.8	0.4	0.5	-0.2	-1.2	-1.8	-0.6
Eye problems/disorders: None of the above	1.1	1.3	3.0	1.5	-1.0	-1.1	-0.6	-0.0	1.7	1.5	0.2	1.3
Mouth/teeth dental problems: Loose teeth	0.6	0.7	1.7	0.1	0.1	0.7	1.3	1.3	-1.1	-0.3	0.8	-0.7
Emphysema/chronic bronchitis	1.4	1.6	3.5	1.9	-1.2	-0.0	1.6	1.9	0.2	1.5	1.1	0.5
Medication for pain relief, constipation, heartburn	1.3	2.2	7.7	-0.9	2.8	1.7	-1.0	-0.1	-1.4	-1.4	0.1	-1.8
Neck or shoulder pain in last month	0.3	0.4	1.6	0.3	-1.3	-0.0	0.8	0.7	0.3	0.2	-0.1	0.5
Medication: Blood pressure	1.0	1.8	5.1	0.9	-0.9	-0.0	1.5	0.7	2.1	0.9	-1.2	2.3
Angina (self-reported)	1.6	2.2	5.8	1.7	-1.5	-0.8	0.1	0.1	1.9	1.2	1.6	2.4
Migraine (self-reported)	1.5	1.9	8.5	0.7	-0.2	0.2	2.9	2.3	-0.3	0.4	-1.6	-0.3
Medication: Ibuprofen	1.2	1.5	10.2	-0.3	-0.7	-3.2	0.8	0.2	0.1	0.3	-1.3	0.2
Medication: Allopurinol	2.1	2.8	8.1	2.1	-1.9	1.9	0.2	0.3	1.7	2.8	0.4	1.3
Medication: Omeprazole	0.6	0.7	3.0	0.9	-0.9	-0.5	-0.3	-0.0	0.8	1.7	0.0	0.8
Medication: Seretide 50 evohaler	0.3	0.3	1.2	1.1	0.8	0.4	0.2	0.4	-0.2	0.7	0.4	0.0
Mean time to correctly identify matches	1.4	2.6	7.8	2.3	-1.7	0.1	-0.2	0.8	1.7	2.8	1.1	1.8
Heart disease (mother)	2.4	2.9	6.7	1.7	-1.9	-1.1	-0.4	-0.2	2.6	2.2	-0.3	2.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.2	0.2	0.6	0.1	-0.4	-0.3	0.2	0.2	0.8	0.5	-0.6	0.7
Whole body fat mass	1.9	7.7	29.8	2.8	-5.5	-1.9	0.5	-0.1	0.7	2.4	3.5	3.0
Leg fat mass (right)	2.3	8.9	32.6	3.0	-5.7	-2.2	0.5	-0.1	0.9	2.6	3.7	3.4
Arm predicted mass (right)	0.2	0.9	4.3	-0.3	-0.3	-2.1	0.1	-0.5	-1.1	-0.8	1.2	0.2
Pulse rate, automated reading	4.8	15.5	55.8	3.0	-7.5	-3.2	3.1	2.1	3.5	4.0	-0.0	4.7
Alcohol intake frequency.	0.8	1.8	6.9	-0.8	-2.6	-2.3	-0.6	-1.6	-0.2	-0.3	0.7	0.2
Comparative height size at age 10	1.3	7.2	11.6	-3.1	2.6	-0.3	-3.0	-2.7	-3.1	-3.4	-0.2	-3.3
Number of full sisters	0.6	0.7	3.0	0.1	0.0	-1.7	-1.2	-1.3	0.2	0.5	0.6	-0.1
Suffer from ‘nerves’	0.3	0.4	1.6	0.6	0.2	0.6	0.1	0.6	0.5	-0.2	1.3	0.8
Overall health rating	1.7	3.6	8.5	2.2	-2.9	-0.7	1.7	1.3	1.6	1.8	1.2	2.6
Chest pain or discomfort	1.2	1.7	3.5	1.9	-1.1	-0.2	1.2	1.3	1.0	1.3	1.6	1.6
Had major operations	0.7	0.8	2.5	-1.4	0.1	-0.4	-0.5	-0.9	-0.9	-1.6	-0.6	-0.6
Age at last live birth	0.7	1.1	2.9	-0.8	1.7	0.3	0.3	0.3	-1.0	-0.8	-1.6	-1.2
Family relationship satisfaction	1.2	1.5	9.6	-0.1	0.4	3.1	0.8	0.9	-1.0	-0.1	0.1	-1.2
Leg pain on walking	0.6	0.7	2.5	-1.6	0.2	-0.7	-0.6	-0.7	-0.6	-1.0	-0.9	-0.5
Qualifications: NVQ or HND or HNC or equivalent	0.4	0.4	2.7	0.6	0.1	-1.6	0.3	0.3	-0.0	0.7	0.0	-0.3
Commuting to job workplace: Car/motor vehicle	1.7	2.0	6.6	-0.0	0.7	-0.5	0.3	0.8	-2.4	-0.9	2.6	-1.7
Illness, injury, bereavement, stress in last 2 years	1.0	1.2	5.2	1.0	-2.3	-0.6	0.9	0.2	0.8	0.9	0.6	1.3
Medication: Aspirin	0.6	0.7	1.6	-1.2	-0.2	0.2	0.4	0.0	-1.3	-1.2	-1.1	-0.9
Supplements: Vitamin C	1.6	1.9	7.5	-1.2	2.7	-0.3	-0.2	0.1	-0.9	-1.3	-1.6	-1.6
Knee pain experienced in last month	2.8	4.3	9.9	2.5	-3.1	-1.3	0.1	-0.1	2.2	2.5	1.0	3.0
Hypertension (Self-reported)	0.6	1.8	4.6	0.3	-2.0	-0.4	1.4	-0.3	1.8	0.7	-1.3	2.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.1	1.2	2.7	0.4	-0.9	-0.1	-1.6	-1.4	1.6	1.2	-0.6	1.0
Illnesses of father: Heart disease	0.9	1.2	3.4	1.2	0.4	1.4	1.8	1.7	0.3	0.7	0.8	0.4
Illnesses of siblings: Diabetes	1.0	1.2	3.1	0.7	-1.8	0.6	1.5	0.7	0.9	0.8	-0.8	1.4
Smoking status: Previous	1.7	2.6	6.2	1.4	-1.3	0.5	2.5	2.3	1.5	0.7	-0.8	2.1
Forced expiratory volume in 1-second (FEV1), predicted	0.8	1.7	4.3	-1.1	2.1	-0.2	-1.1	-0.3	-1.7	-1.2	-0.5	-2.0
Whole body fat-free mass	0.2	1.2	4.1	-0.6	0.1	-2.0	-0.2	-0.7	-1.7	-1.1	1.1	-0.5
Leg fat-free mass (right)	0.2	1.3	5.4	-0.4	-0.7	-2.3	-0.1	-0.8	-1.6	-0.9	1.4	-0.1
Arm fat percentage (left)	3.1	12.3	42.9	3.7	-6.5	-1.9	1.4	0.6	2.1	3.6	3.2	4.4
Average weekly red wine intake	1.3	1.9	10.4	-0.9	3.2	-0.1	-1.5	-0.8	-0.5	-1.3	0.3	-1.1
Handedness (chirality/laterality): Left-handed	0.2	0.2	1.1	-0.1	1.1	-0.7	0.2	0.0	-0.1	-0.1	-0.5	-0.4
Mood swings	0.9	1.6	6.1	0.9	-2.5	-0.0	0.2	0.4	1.3	0.6	1.6	1.7
Loneliness, isolation	0.7	1.0	1.5	1.1	-1.2	0.8	0.8	1.1	0.9	1.0	0.9	0.8
Long-standing illness, disability or infirmity	0.7	1.1	3.3	0.6	-1.2	-1.0	1.8	0.7	0.8	0.6	-0.2	1.4
Ever had bowel cancer screening	0.5	0.6	1.7	0.5	-1.2	1.3	0.8	1.0	0.1	0.4	0.5	0.5
Diabetes diagnosed by doctor	0.5	0.8	2.0	0.7	-1.3	1.1	1.1	1.4	-0.2	0.4	0.4	0.2
Ever had stillbirth, spontaneous miscarriage or termination	0.3	0.3	1.4	-0.1	1.2	-0.4	-0.0	0.3	0.6	-0.5	-0.7	0.1
Friendships satisfaction	0.8	0.9	4.3	0.3	-0.3	2.1	0.5	1.2	-0.9	0.3	0.7	-1.0
Qualifications: nursing, teaching	1.8	2.8	5.5	-2.3	2.0	-0.2	-1.4	-1.3	-1.2	-1.6	-2.3	-1.7
Commuting to job workplace: Walk	0.7	0.8	2.8	0.0	-1.0	0.3	0.1	-0.6	1.3	0.8	-1.7	0.9
Eye problems/disorders: Cataract	1.1	1.3	3.6	-1.5	0.6	0.6	0.3	-0.0	-1.9	-1.9	0.0	-1.2
Mouth/teeth dental problems: Mouth ulcers	0.6	1.0	3.5	0.9	-1.9	-0.9	0.7	-0.2	1.0	1.2	-0.2	1.0
Medication for cholesterol	0.8	1.2	6.1	-0.1	2.5	1.3	-1.4	-0.0	0.7	-0.0	-0.5	-0.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.7	0.8	3.4	0.5	-1.0	0.7	1.8	0.7	0.6	0.3	-0.4	1.0
Back pain experienced in last month	0.6	0.9	4.6	-0.9	-0.0	-2.1	0.3	-0.1	-0.2	-0.9	-1.3	0.3
Mineral and other dietary supplements	1.5	2.1	4.7	0.8	-0.6	-2.2	-1.2	-1.2	1.8	1.6	1.2	1.7
Breast cancer (self-reported)	1.2	1.4	3.7	-1.5	0.8	-1.3	-1.2	-1.9	-0.3	-1.8	0.1	0.1
Asthma (self-reported)	0.5	1.0	2.8	0.5	1.4	0.4	-1.3	-1.4	0.2	0.4	1.7	0.2
Osteoporosis (self-reported)	1.2	1.4	3.3	1.5	-0.9	0.8	1.3	1.5	1.2	1.8	-0.1	0.9
Osteoarthritis (self-reported)	0.3	0.4	1.3	-0.9	-0.7	-0.6	0.5	-0.3	-1.1	-0.8	0.1	-0.3
Medication: Aspirin	0.4	0.5	1.2	-0.5	-0.4	0.0	1.1	0.7	-0.7	-0.7	-1.1	-0.2
Medication: Gliclazide	0.3	0.4	0.6	0.6	-0.8	-0.3	0.8	0.8	0.4	0.7	-0.5	0.6
Illnesses of father: None of the above (group 1)	1.3	1.6	3.6	-1.9	1.1	0.4	-1.2	-0.9	-1.2	-1.2	-1.0	-1.8
Smoking status: Current	0.7	1.1	3.5	-0.5	0.2	-0.4	-0.9	-1.1	-1.4	-0.7	1.9	-1.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.7	1.4	4.9	-1.2	1.8	0.5	0.2	0.5	-0.1	-0.9	-2.2	-1.2
Whole body water mass	0.2	1.1	3.8	-0.6	0.1	-1.9	-0.1	-0.7	-1.6	-1.0	1.1	-0.4
Leg predicted mass (right)	0.3	1.3	5.5	-0.3	-0.8	-2.3	-0.1	-0.8	-1.6	-0.8	1.4	-0.1
Arm fat mass (left)	2.1	8.4	30.0	2.9	-5.5	-2.1	0.9	0.1	1.2	2.7	3.3	3.5
Number of self-reported non-cancer illnesses	0.4	0.6	4.3	-0.6	-2.1	0.3	0.6	-0.6	-0.3	-0.2	-0.3	0.2
Average weekly champagne plus white wine intake	1.8	2.5	6.6	1.6	-0.5	-0.1	0.4	1.2	2.6	2.1	-1.8	1.9
Miserableness	0.7	1.2	2.7	1.0	-0.3	1.1	1.3	1.5	1.6	0.4	0.1	1.3
Guilty feelings	0.3	0.4	1.7	-0.6	-0.3	1.3	0.4	-0.2	0.3	-0.8	-0.6	0.1
Wears glasses or contact lenses	1.5	1.8	6.6	1.1	-2.6	-1.1	0.0	-0.3	0.8	1.3	0.9	1.9
Ever taken oral contraceptive pill	0.4	0.5	1.3	0.5	1.0	1.1	-0.5	-0.2	0.9	0.6	0.3	0.5
Hearing aid user	0.2	0.3	1.3	-0.0	-0.8	-0.5	1.1	0.2	-0.6	0.1	-0.1	-0.0
Mother’s age at death	0.7	0.9	2.0	-0.8	0.8	0.9	-0.3	-0.2	-1.3	-1.2	1.4	-0.7
Financial situation satisfaction	0.7	0.9	3.2	-0.5	-1.2	0.4	-1.8	-1.3	-0.0	0.1	0.9	-0.2
Tinnitus: Yes, now most or all of the time	2.3	2.7	6.0	1.9	-2.3	-1.3	0.5	0.1	1.6	2.4	1.0	1.9
Commuting to job workplace: Public transport	0.7	0.9	2.5	-0.2	-1.2	0.5	-0.5	-0.1	1.4	0.2	-1.6	1.2
Eye problems/disorders: Glaucoma	0.6	0.7	1.8	-0.9	0.5	1.3	0.6	0.6	-0.7	-1.4	-0.6	-0.4
Medication: Blood pressure	0.4	0.8	3.7	-0.8	-1.9	-0.4	0.6	-0.6	-0.6	-1.2	0.3	0.1
Pain type(s) experienced in last month: Hip pain	1.8	2.3	6.1	1.9	-1.3	0.3	0.6	0.8	1.9	1.5	1.3	2.5
Supplements: Fish oil (including cod liver oil)	2.1	2.7	5.9	-1.7	1.4	1.7	0.3	0.4	-2.1	-2.4	-1.2	-2.2
High cholesterol (Self-reported)	1.0	1.8	10.4	0.5	-3.2	0.0	1.6	0.8	0.1	0.5	0.4	1.1
Medication: Bendroflumethiazide	0.4	0.5	1.4	-0.6	-1.0	-0.2	0.1	-0.6	1.2	-0.5	-0.3	1.2
Medication: Paracetamol	3.7	5.8	11.3	2.6	-3.4	-2.2	2.2	1.3	2.2	2.6	1.7	2.8
Medication: Lisinopril	0.7	0.9	2.6	0.8	-0.6	-1.6	-0.1	-0.6	1.4	0.9	-0.2	1.3
Medication: Atorvastatin	3.0	3.7	6.6	2.2	-2.4	-1.0	2.6	2.0	1.4	2.0	0.5	2.3
Illnesses of father: High blood pressure	0.5	0.7	2.4	0.9	-1.6	0.1	0.3	0.2	0.9	0.7	0.1	1.1
Alcohol drinker status: Never	0.8	0.9	1.4	-1.1	-0.9	-0.7	-1.1	-1.1	-1.2	-0.9	0.1	-1.1
Ever smoked	0.4	0.7	1.4	1.0	-0.6	0.8	1.1	1.2	0.3	0.7	0.7	0.5
Basal metabolic rate	0.2	1.2	5.2	-0.0	-0.9	-2.3	-0.1	-0.7	-1.3	-0.4	1.6	0.1
Leg fat percentage (left)	3.1	11.1	39.6	3.7	-6.3	-1.9	1.0	0.7	1.5	3.3	3.6	3.9
Arm fat-free mass (left)	0.2	1.0	4.0	-0.4	-0.1	-2.0	-0.0	-0.6	-1.5	-0.6	1.2	-0.3
Number of operations (self-reported)	0.7	1.0	3.5	0.3	-1.9	-1.2	1.4	0.1	0.1	-0.1	-0.1	1.3
Average weekly beer plus cider intake	1.4	2.0	4.9	-0.7	-0.6	-1.5	-1.8	-1.8	-1.3	-0.8	2.2	-1.1
Irritability	0.3	0.5	1.6	-0.9	1.2	0.2	-0.1	0.3	0.0	-1.0	-1.0	-0.6
Risk taking	0.5	0.7	1.6	0.6	-0.1	1.3	1.1	1.0	0.7	0.4	-0.2	1.2
Ever had prostate specific antigen (PSA) test	0.6	0.7	1.3	0.5	-0.8	0.7	1.2	0.9	0.4	0.1	-1.0	1.1
Fractured/broken bones in last 5 years	0.3	0.4	1.1	0.7	1.0	-0.3	0.6	0.4	0.6	0.8	0.4	0.4
Age started oral contraceptive pill	0.3	0.3	1.2	-0.4	0.0	1.1	0.9	0.1	0.3	-0.4	-0.2	0.6
Diastolic blood pressure, automated reading	0.8	2.6	13.2	0.8	-1.6	-3.6	1.5	0.1	0.9	1.1	-0.4	1.5
Ever depressed for a whole week	0.2	0.2	0.6	-0.0	0.5	0.8	-0.1	0.0	0.1	-0.4	0.8	0.5
Unable to work because of sickness or disability	0.4	0.5	1.9	0.5	-0.5	-0.3	-0.5	-0.7	0.8	0.7	0.1	1.4
Commuting to job workplace: Cycle	1.5	1.8	4.4	-1.8	1.4	-0.5	-0.5	-0.8	-1.5	-1.5	-1.0	-2.1
Myopia	0.7	1.0	2.7	-1.3	0.0	0.2	0.2	0.3	-1.6	-1.5	-0.5	-1.7
Vascular/heart problems diagnosed by doctor	0.9	2.4	7.3	-0.9	2.3	0.6	-1.4	0.2	-2.1	-1.1	1.0	-2.7
Cholesterol lowering medication	1.2	1.8	5.3	-0.2	-2.3	-2.0	2.0	0.6	-1.1	-0.8	0.6	0.3
Medication: Omeprazole (e.g. Zanprol)	0.5	0.6	2.2	0.8	-0.9	0.1	0.1	0.4	0.7	1.5	-0.6	0.6
Pain experienced in last month	1.9	3.1	9.5	-1.1	2.6	3.1	-0.4	0.8	-1.4	-1.2	-0.8	-2.3
Supplements: Calcium	0.9	1.0	3.9	-1.2	0.8	2.0	-0.1	-1.0	-0.3	-1.3	-0.6	-0.5
Basal cell carcinoma (self-reported)	0.2	0.2	0.7	0.5	-0.3	-0.3	0.7	0.8	0.4	0.6	-0.1	0.3
Heart attack/myocardial infarction (self-reported)	2.1	2.7	7.3	1.8	-1.3	0.8	2.7	2.4	0.1	0.5	2.0	1.0
Deep venous thrombosis (DVT) (self-reported)	0.4	0.5	2.3	0.3	0.5	-0.0	0.5	0.4	-1.0	0.3	1.5	-0.7
Heart disease (siblings)	0.1	0.2	0.7	-0.2	-0.3	-0.1	0.0	-0.6	0.2	-0.4	0.2	0.8
Alcohol drinker status: Previous	0.3	0.3	1.0	0.3	-0.1	0.3	0.4	0.3	1.0	0.7	-0.8	0.7
Pack years of smoking	0.5	0.8	2.3	0.5	-1.5	0.4	0.4	-0.1	1.1	0.9	-0.3	1.4
Impedance of whole body	0.1	0.5	1.3	0.4	-0.7	1.0	-0.4	0.5	0.1	1.0	-0.7	-1.2
Leg fat mass (left)	2.1	8.1	30.3	2.9	-5.5	-2.3	0.6	0.1	0.7	2.5	3.5	3.2
Arm predicted mass (left)	0.2	1.1	3.9	-0.5	-0.0	-2.0	-0.0	-0.6	-1.6	-0.9	1.3	-0.2