Hub : Genes

NEO1

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0550	0.0270	1.3e-02	-0.001	0.016	0.007	0.020	0.004	4.7e-01	3.9e-03	4.7e-02	1.5e-03	8.4e-02
2	GTEx	Cells Transformed fibroblasts	0.3710	0.0680	2.0e-09	0.283	NA	0.255	NA	0.271	2.2e-21	NA	3.5e-19	NA	2.1e-20
3	GTEx	Esophagus Muscularis	0.1970	0.0550	4.8e-08	0.126	NA	0.159	NA	0.172	4.9e-08	NA	6.7e-10	NA	1.1e-10
4	GTEx	Nerve Tibial	0.0708	0.0299	2.6e-03	0.091	NA	0.087	NA	0.093	5.5e-07	NA	1.0e-06	NA	3.9e-07
5	GTEx	Spleen	0.3910	0.1250	2.8e-03	0.004	NA	-0.011	NA	0.007	2.5e-01	NA	9.0e-01	NA	2.0e-01
6	METSIM	Adipose	0.0429	0.0188	3.0e-03	0.004	0.005	0.005	0.010	0.004	7.8e-02	4.8e-02	4.6e-02	1.1e-02	7.7e-02
7	NTR	Blood	0.0434	0.0155	1.2e-05	0.013	0.014	0.010	0.015	0.016	2.7e-05	2.3e-05	2.2e-04	8.0e-06	4.1e-06
8	TCGA	Pancreatic Adenocarcinoma	0.2420	0.1270	6.3e-04	0.026	0.049	0.021	NA	0.021	2.9e-02	4.1e-03	4.3e-02	NA	4.3e-02
9	TCGA	Thyroid Carcinoma	0.0330	0.0210	6.8e-03	0.023	0.017	0.005	NA	0.018	2.4e-03	7.5e-03	9.3e-02	NA	6.2e-03

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Bipolar Disorder (2018)	0.5	0.7	2.0	1.2	-0.6	0.2	0.2	1.1	0.6	1.4	-1.0	0.3
Bipolar Disorder or Schizophrenia	0.8	1.9	6.3	2.1	-0.7	0.4	-0.0	1.6	0.8	2.5	-0.8	1.5
Depressed Affect (Nagel 2018)	0.8	1.6	3.7	-1.7	-0.5	-1.9	1.8	-0.4	0.1	-0.4	-1.2	-1.6
Depression (Nagel 2018)	0.7	1.0	4.1	-1.6	0.1	-0.9	0.8	-0.1	0.5	-0.4	0.8	-2.0
Intelligence (Savage-Jansen 2018)	0.6	1.9	4.5	-0.4	0.9	-2.1	2.0	0.5	-1.7	0.4	2.0	-0.1
Neuroticism (Nagel 2018)	0.5	1.2	4.4	-1.1	-0.6	-1.9	2.1	0.3	0.3	0.7	-0.5	-1.0
Schizophrenia (2018)	0.7	1.4	4.4	1.7	-0.4	0.3	-0.3	1.2	0.6	2.1	-0.2	1.6
Schizophrenia vs Biploar Disorder	0.4	0.6	1.3	0.0	-0.1	1.1	-0.8	0.6	1.1	0.9	-0.2	0.9
Worry (Nagel 2018)	0.4	0.8	2.1	-1.1	-0.8	-0.6	1.0	0.1	1.4	0.9	0.2	-0.7
Alzheimer’s Disease (in mother)	2.2	2.5	4.9	0.8	2.1	0.6	-1.0	-1.4	-2.2	-2.0	-2.2	-0.9
Alzheimer’s Disease (in father)	0.3	0.4	1.5	0.2	-0.7	0.0	0.1	-0.3	1.0	0.4	-1.2	-0.4
Alzheimer’s Disease (including proxy)	0.5	0.7	1.8	0.1	1.1	0.0	-0.1	-0.6	-1.4	-1.1	-1.2	-0.3
Crohns Disease (2017)	0.1	0.2	0.6	-0.2	-0.2	0.2	-0.0	0.8	-0.0	0.5	0.7	-0.5
Irritable Bowel Disease (IBD)	0.3	0.6	2.4	-1.3	-0.1	-0.1	0.3	1.0	0.2	0.2	1.6	-0.6
Ulcerative Colitis (UC)	0.3	0.6	2.6	-1.3	0.0	-0.2	0.3	1.0	0.4	0.2	1.6	-0.2
Major Depression (MDD)	1.4	1.7	7.2	-1.5	-0.2	1.6	-1.0	-0.8	1.0	-0.3	-2.7	-0.9
Reaction Time	1.0	1.9	6.7	-1.8	-2.6	-0.3	0.4	-0.3	2.6	-0.2	-0.8	-0.4
Verbal and Numeric Reasoning (VNR)	0.9	2.2	5.1	-0.1	1.9	-2.2	1.7	0.1	-2.3	-0.0	1.7	-0.3
Breast Cancer	0.3	0.7	2.6	0.7	-1.6	0.6	-0.4	0.4	1.3	0.8	-0.7	0.0
Ovarian Cancer	0.6	0.8	3.5	0.3	0.7	1.5	-1.9	0.2	0.3	0.3	0.9	0.2
Prostate Cancer	0.7	1.0	2.0	0.4	-1.2	-0.7	1.1	-0.1	1.4	1.4	-1.3	0.2
Age at First Birth	0.5	0.7	3.5	1.9	0.2	-0.7	0.4	0.6	-0.4	0.8	0.4	0.9
Bipolar Disorder (2011)	0.6	0.6	1.5	1.1	-0.8	-0.8	0.9	-0.2	-0.2	0.3	-1.2	-0.6
Body Mass Index (BMI) (2010)	0.5	0.7	1.7	-0.2	0.5	0.9	-0.9	-1.1	-0.3	-0.6	-1.0	-1.3
Coronary Artery Disease (CAD)	1.0	1.2	4.5	-2.1	1.4	0.2	-0.6	-0.9	-1.1	-1.5	0.3	-0.2
Crohns Disease (2012)	0.2	0.4	1.7	-0.6	-0.3	-0.1	0.6	-0.0	0.5	0.6	0.6	-1.3
Mean Putamen Volume	0.5	0.6	1.6	-0.9	1.3	-0.3	-0.4	-0.3	-1.3	-0.4	0.7	0.6
Fasting Glucose	0.6	0.7	1.4	-1.0	1.0	-1.2	0.9	-0.8	-0.4	-0.6	1.0	-0.6
HbA1C	1.1	1.2	3.6	1.4	-1.3	0.0	0.3	1.1	1.4	1.9	-0.6	0.4
HDL Cholesterol	0.4	0.7	1.8	0.7	-0.4	-1.1	1.1	0.4	0.3	1.1	0.1	1.3
LDL Cholesterol	0.3	0.4	1.3	0.5	-1.1	0.3	-0.1	0.7	1.0	0.3	-0.6	0.5
Lupus	0.3	0.5	2.1	-0.8	-0.9	0.5	-0.3	0.2	1.5	-0.1	-0.1	-0.4
Neuroticism (2016)	0.5	0.8	2.5	0.1	0.3	1.6	-1.2	-0.4	-0.5	-0.6	-0.9	-1.1
Primary Biliary Cirrhosis	0.3	0.4	2.0	0.5	0.3	0.2	-0.1	0.8	-0.3	1.4	-0.3	0.5
Rheumatoid Arthritis	0.4	0.6	1.6	-0.3	0.2	-0.8	0.9	1.1	-0.6	0.6	0.8	1.3
Schizophrenia (2014)	0.9	1.9	6.5	2.0	-0.8	-0.5	0.7	1.2	0.5	2.5	-1.0	1.5
Triglycerides	3.1	5.1	15.3	-2.4	1.1	1.7	-2.2	-2.7	-1.5	-3.9	-1.2	-2.0
Type 2 Diabetes (T2D) (2012)	1.8	2.0	4.6	-2.2	0.4	1.3	-1.5	-2.0	0.8	-1.0	-0.9	-1.7
Ulcerative Colitis	0.5	0.7	2.1	-0.8	1.0	-1.0	0.7	0.6	-0.7	-0.2	1.4	-0.4
Blood Eosinophil Count	0.6	4.7	10.8	-1.6	1.8	2.3	-2.7	-2.3	0.2	-3.3	-0.6	-2.8
Blood Platelet Count	0.1	1.6	10.2	-0.6	0.1	0.7	-1.0	-1.2	0.9	-0.5	0.3	-3.2
Blood Red Count	0.1	0.9	2.7	-1.6	-0.7	0.6	-0.3	-1.0	-0.9	0.3	-1.6	-0.1
Blood White Count	0.7	5.1	12.0	-2.9	2.3	1.0	-1.9	-2.8	-1.2	-3.5	-1.6	-2.1
Heel T-Score	0.5	4.3	17.9	-0.9	1.5	-2.6	1.9	-0.4	-4.2	-2.4	-1.1	-0.4
BMI	3.1	17.8	35.9	-4.7	3.7	4.7	-6.0	-4.4	-1.2	-5.5	-3.2	-2.3
Height	0.3	5.2	16.2	2.1	1.2	2.7	-2.7	2.9	-0.0	-0.2	1.5	4.0
Waist Hip Ratio (WHR)	1.3	5.7	14.0	-3.0	0.3	-0.4	0.5	-3.7	-1.3	-2.9	-2.0	-3.7
Systolic Blood Pressure	0.5	2.6	7.3	-1.9	-1.6	-2.4	2.7	0.2	0.2	1.2	1.6	-0.4
Smoking Status	0.8	1.8	6.1	-2.5	-0.4	1.6	-1.2	-0.8	1.8	-0.7	-1.2	-0.6
Allergy or Eczema	0.2	0.5	1.7	0.9	0.1	-1.3	1.1	0.1	-0.4	-0.1	0.2	0.3
Cardiovascular Disease	0.7	2.4	5.0	-1.6	0.3	2.2	-1.9	-1.9	-0.1	-1.8	-0.7	-1.7
Hypothyroidism (self reported)	0.6	1.4	3.8	-1.3	1.1	-0.1	-0.5	-0.9	-2.0	-1.8	0.3	-1.2
Respiratory disease	0.1	0.2	1.1	-0.0	1.0	-0.1	-0.2	-0.1	-0.4	-0.9	0.2	0.0
Type 2 Diabetes (T2D) (2018)	2.2	4.1	11.8	-1.3	1.0	1.5	-1.7	-3.0	-0.4	-3.4	-0.9	-2.7
Lung FEV1/FVC ratio	1.2	5.9	24.3	-4.9	-3.4	-2.0	2.5	-1.2	1.3	1.2	-0.4	-1.4
Lung FVC	0.9	4.5	16.9	0.8	-1.3	-3.9	4.1	1.3	0.5	1.7	1.0	0.6
Neuroticism	0.4	1.0	3.0	0.1	-0.8	-1.3	1.7	0.8	-0.3	0.7	-1.3	-0.6
Chronotype (morning person)	2.6	6.1	14.0	0.5	3.4	3.0	-3.7	-2.0	-2.3	-3.1	-0.8	-0.5
Hair Pigment	0.4	11.1	21.5	3.2	1.8	-3.6	2.9	4.6	-3.0	3.1	2.4	4.3
Tanning	0.1	1.8	3.3	1.2	-0.6	1.7	-1.4	0.9	1.7	0.8	-1.8	1.4
Hand grip strength (left)	0.3	0.9	1.8	0.1	1.3	-1.0	0.4	-0.0	-1.1	-1.3	0.8	1.3
Number of treatments/medications taken	2.4	4.2	9.9	-1.9	1.0	1.5	-2.0	-3.1	-0.9	-2.6	-1.0	-2.9
Average weekly spirits intake	2.2	2.7	7.6	-2.2	0.6	0.0	-0.1	-2.3	-0.7	-2.8	0.6	-2.3
Sensitivity / hurt feelings	1.2	2.0	8.8	1.3	-0.6	-1.2	1.5	1.2	-0.3	0.7	-3.0	1.2
Frequency of depressed mood in last 2 weeks	0.3	0.4	1.0	-0.9	0.6	-1.0	0.7	0.7	-0.2	0.1	0.4	-0.3
Hearing difficulty/problems: Yes	0.2	0.3	1.3	-0.8	0.1	0.1	-0.3	0.2	-0.1	0.3	1.1	-0.6
Relative age of first facial hair	0.2	0.4	1.1	0.6	0.3	0.6	-0.9	1.1	0.2	0.8	0.0	0.7
Other serious medical condition/disability diagnosed by doctor	1.7	2.2	10.6	-0.3	1.7	-1.9	1.1	0.4	-3.3	0.4	0.8	0.4
Ever used hormone-replacement therapy (HRT)	0.7	0.8	2.9	0.5	-1.0	1.3	-1.1	0.3	1.7	0.5	0.0	-0.3
Ever had hysterectomy (womb removed)	0.5	0.5	1.5	0.9	0.1	0.1	-0.3	0.7	-1.2	0.5	1.0	0.8
Systolic blood pressure, automated reading	0.7	1.9	4.8	-1.0	-0.4	-2.2	2.2	1.2	-0.9	1.4	1.0	1.1
Eye problems/disorders: Diabetes related eye disease	0.7	0.8	2.6	-0.0	-0.7	1.0	-0.2	-1.2	0.3	-0.3	-1.6	-1.0
Angina	0.6	0.8	3.3	-1.8	1.1	0.2	-0.5	-0.3	-0.6	-0.6	-0.6	-0.9
Medication for hormone replacement therapy	0.4	0.4	1.1	1.1	-0.4	0.8	-0.3	0.7	0.9	0.6	0.5	-0.2
Vitamin and mineral supplements	2.3	3.1	11.3	-3.4	-0.2	1.4	-1.4	-2.2	-0.5	-2.0	0.9	-1.7
Supplements: Zinc	0.7	0.8	3.3	1.8	-0.2	0.4	-0.1	0.8	1.0	1.1	0.7	0.5
Medication: Co-codamol	0.5	0.6	1.5	-0.2	0.5	-1.1	0.6	-1.0	-0.9	-1.2	-0.4	-0.1
Medication: Metformin	1.7	2.5	4.8	-2.1	0.6	1.2	-1.5	-2.2	0.2	-2.1	-0.7	-2.0
Diabetes (father)	0.8	1.0	2.1	0.9	1.2	0.6	-0.8	-0.9	-0.4	-1.4	-1.1	-1.2
Diabetes (mother)	1.0	1.2	3.2	-1.2	0.4	1.4	-1.3	-0.6	1.1	-1.8	-0.9	-0.3
Severe depression (siblings)	4.3	4.9	16.7	1.3	-2.4	-1.0	1.7	2.8	2.3	4.1	0.3	1.4
Pack years adult smoking proportion	0.7	1.1	3.9	-1.7	-0.2	1.1	-0.8	-0.7	-0.1	-0.8	-2.0	-0.0
Impedance of leg (right)	0.5	2.2	9.4	-1.2	-1.4	0.4	-0.2	-1.7	1.6	-0.9	0.5	-3.1
Leg fat-free mass (left)	0.9	4.8	10.9	-0.1	2.9	2.8	-3.3	-0.0	-0.9	-2.1	-2.6	2.0
Trunk fat percentage	4.6	18.4	39.1	-4.0	1.9	6.0	-6.2	-4.4	0.8	-5.4	-3.0	-3.5
Hand grip strength (right)	0.3	0.9	3.1	1.0	1.5	-0.5	-0.0	0.5	-0.8	0.0	0.7	1.8
Townsend deprivation index at recruitment	0.2	0.2	1.0	-1.0	0.4	0.4	-0.1	-0.1	-0.5	-0.5	0.4	-0.2
Current tobacco smoking	0.6	1.0	3.4	-1.3	-0.1	1.1	-0.8	0.5	1.8	0.2	-1.2	0.8
Average weekly fortified wine intake	1.7	2.0	6.6	0.7	0.3	-1.8	1.6	1.8	-0.5	1.2	2.6	0.4
Maternal smoking around birth	1.0	1.5	5.9	-0.5	-2.1	0.9	-0.2	0.9	2.4	0.9	0.6	-0.1
Fed-up feelings	1.5	2.7	9.4	-0.5	-1.5	-2.9	3.1	0.8	0.6	1.3	-1.1	-0.3
Frequency of unenthusiasm / disinterest in last 2 weeks	0.6	0.8	2.0	-1.4	-0.6	-1.0	0.9	0.1	0.8	0.1	0.7	-1.3
Relative age voice broke	0.6	0.9	2.0	0.9	0.0	0.5	-0.6	1.2	1.2	1.2	-0.6	1.4
Taking other prescription medications	0.7	1.1	3.7	-1.9	0.1	0.5	-0.9	-1.5	-0.4	-0.9	-0.5	-1.4
Age when periods started (menarche)	0.6	1.4	6.2	0.8	2.5	1.3	-1.9	-0.1	-0.8	-0.1	0.2	0.4
Bilateral oophorectomy (both ovaries removed)	1.0	1.2	2.5	-0.5	-1.0	1.6	-1.1	-0.9	1.2	-1.0	-1.5	-0.5
Heel bone mineral density (BMD) T-score, automated (left)	0.8	1.8	6.0	-0.6	-0.8	-2.2	2.5	0.8	-0.6	1.6	-0.7	0.8
Tinnitus: Yes, but not now, but have in the past	0.2	0.2	0.7	0.0	-0.5	0.5	-0.0	-0.4	0.9	0.1	-0.7	0.5
Qualifications: CSEs or equivalent	0.2	0.3	0.8	0.5	-0.0	0.7	-0.4	-0.1	0.9	-0.3	-0.8	0.1
Serious illness, injury or assault to yourself	0.6	0.8	2.3	-1.1	0.2	-1.5	1.0	1.0	-0.9	0.2	0.4	0.5
High blood pressure	0.4	1.1	2.8	0.7	1.1	1.7	-1.6	-0.1	-1.4	-0.4	-1.0	0.2
Hayfever, allergic rhinitis or eczema	0.2	0.4	1.1	0.8	-0.7	-1.1	1.1	-0.1	0.6	0.0	-0.3	-0.3
Multivitamins +/- minerals	1.3	1.7	8.4	2.9	0.7	-1.0	0.7	0.7	-0.1	0.7	-1.8	0.8
Stomach or abdominal pain in last month	0.3	0.4	1.0	0.5	-0.3	0.6	-0.3	-1.0	0.9	-0.2	-0.2	-1.0
Supplements: Glucosamine	0.5	0.7	3.5	1.9	0.2	-0.8	0.7	0.6	0.1	0.9	-0.1	-0.7
Diverticular disease/diverticulitis (self-reported)	0.1	0.2	0.4	-0.3	-0.6	-0.5	0.6	0.3	-0.3	-0.1	-0.0	0.4
Medication: Atenolol	1.1	1.3	3.9	-0.4	1.7	1.9	-2.0	-0.4	-0.8	-0.2	0.8	-0.2
Medication: Levothyroxine sodium	0.7	1.1	3.5	-0.5	1.4	-0.2	-0.5	-1.0	-1.9	-1.5	0.1	-1.1
Sitting height	0.7	5.1	20.1	1.6	2.8	0.8	-1.3	3.2	-1.5	0.9	0.1	4.5
Chronic bronchitis/emphysema (father)	0.6	0.6	2.0	-0.4	0.3	-0.9	0.9	1.1	-0.5	-0.0	1.4	0.9
High blood pressure (mother)	0.7	1.0	3.3	1.8	0.4	0.5	0.0	1.5	0.3	0.9	1.3	-0.2
Body mass index (BMI)	1.9	8.2	13.5	-3.3	1.6	3.2	-3.6	-3.2	0.1	-3.7	-3.0	-2.1
Impedance of leg (left)	0.6	2.9	10.2	-1.5	-1.3	0.8	-0.7	-1.9	2.0	-1.2	1.1	-3.2
Leg predicted mass (left)	0.9	4.7	10.8	-0.2	2.9	2.7	-3.3	-0.1	-0.9	-2.2	-2.6	2.0
Trunk fat mass	4.0	17.1	40.1	-3.6	2.5	5.9	-6.3	-3.9	0.5	-5.2	-3.2	-2.6
Waist circumference	3.5	12.8	21.5	-4.2	1.4	4.3	-4.6	-3.7	0.8	-4.6	-3.0	-3.2
Number of incorrect matches in round	1.0	1.6	4.5	0.6	-1.1	2.0	-1.2	-0.6	1.3	0.1	-0.8	-2.1
Past tobacco smoking	0.7	1.4	3.6	1.9	-0.1	-1.5	1.7	1.3	-0.9	0.7	-0.0	0.7
Alcohol usually taken with meals	1.6	2.6	5.5	-0.1	-0.1	-2.2	1.7	2.3	-1.4	1.1	1.8	2.1
Nervous feelings	1.5	2.8	8.6	-0.3	-2.7	-0.2	1.5	1.4	2.9	2.1	0.2	0.2
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.3	1.1	-0.9	0.2	-0.1	-0.1	-0.3	0.3	-0.2	0.6	-1.1
Hearing difficulty/problems with background noise	0.2	0.2	0.5	-0.2	0.4	0.6	-0.6	0.7	0.4	0.3	-0.5	-0.4
Hair/balding pattern: Pattern 2	0.2	0.3	0.7	0.6	-0.5	-0.2	0.4	0.3	-0.2	0.7	0.5	0.8
Had menopause	1.8	2.2	6.6	0.8	0.1	-0.2	0.4	2.6	-0.7	1.8	1.5	2.5
Had other major operations	0.9	1.1	4.5	0.3	1.3	1.1	-1.4	-0.5	-0.3	-0.4	-2.1	0.3
Forced vital capacity (FVC)	0.7	2.9	7.3	0.6	0.2	-2.7	2.2	2.3	-0.3	0.9	1.8	1.9
Heel bone mineral density (BMD) T-score, automated (right)	0.8	1.9	7.1	-0.9	-0.7	-2.3	2.7	0.6	-1.0	1.2	-0.3	0.5
Ever unenthusiastic/disinterested for a whole week	1.2	1.5	5.8	-0.8	-1.7	0.6	-0.0	-0.2	2.4	0.5	-1.9	-0.2
Qualifications: None of the above	1.2	2.6	4.0	-1.6	0.6	1.8	-1.3	-2.0	-0.3	-1.8	-2.0	-1.9
Financial difficulties in last 2 years	0.7	0.9	4.8	-2.2	-0.4	-0.6	0.9	0.6	1.3	-0.3	-0.1	-0.5
Mouth/teeth dental problems	2.7	4.1	10.6	1.5	1.6	-3.3	2.4	2.1	-2.2	0.3	2.2	1.5
Heart attack	1.5	1.9	5.9	-1.0	1.7	0.4	-0.8	-2.0	-1.1	-2.4	-1.0	-0.8
Allergy	0.1	0.3	1.1	-1.0	-0.1	0.6	-0.3	-0.3	0.2	-0.3	0.1	-1.0
Pain all over the body in last month	0.5	0.5	1.7	-0.9	-0.3	-1.2	0.8	0.1	0.2	-0.5	1.3	-0.1
Diabetes (self-reported)	1.2	1.9	4.3	-1.1	-0.1	1.3	-1.2	-2.0	0.8	-1.9	-0.5	-2.1
Hayfever/allergic rhinitis (self-reported)	0.8	1.0	2.1	-0.4	-1.1	1.0	-0.6	-1.4	1.3	-0.9	-0.4	-1.3
Medication: Ramipril	0.5	0.7	2.1	-0.2	1.0	0.5	-0.9	-0.9	0.0	-1.4	-1.0	-0.0
Medication: Simvastatin	2.9	4.3	8.9	-1.1	0.8	2.0	-1.9	-2.9	-0.6	-3.0	-2.4	-2.4
Fluid intelligence score	0.6	1.2	3.5	-0.6	1.5	-0.8	0.1	-1.1	-1.9	-0.7	1.3	-0.8
Illnesses of siblings	0.7	1.0	3.0	1.7	-0.2	-0.8	0.9	0.4	0.9	1.4	0.7	0.9
Neuroticism score	0.4	0.8	2.7	-0.0	-0.7	-1.2	1.3	0.2	0.3	-0.0	-1.6	-0.7
Weight	1.9	9.1	23.9	-2.3	2.3	4.3	-4.9	-2.2	0.2	-3.8	-3.0	-0.6
Impedance of arm (right)	0.3	1.4	3.7	-0.3	-1.3	1.4	-0.9	-1.3	1.4	-1.1	-0.1	-1.9
Arm fat percentage (right)	3.6	14.2	24.5	-3.8	1.8	4.5	-4.9	-4.4	0.2	-5.0	-3.1	-3.5
Trunk fat-free mass	0.4	2.3	6.4	0.7	2.2	1.1	-1.7	1.0	-0.8	-0.8	-1.4	2.5
Hip circumference	2.1	9.1	24.5	-2.7	1.0	4.8	-5.0	-2.2	2.1	-3.2	-2.0	-1.5
Time employed in main current job	0.5	0.5	3.2	0.3	0.3	-0.7	0.4	0.4	-0.3	-0.7	1.8	0.1
Alcohol intake versus 10 years previously	0.7	1.1	2.3	0.0	-0.2	1.2	-0.8	-1.5	-0.3	-1.4	-1.4	-1.3
Father’s age at death	1.4	1.9	6.4	1.6	-0.7	-0.3	0.4	1.9	0.7	1.8	2.5	0.9
Worrier / anxious feelings	0.1	0.1	0.5	-0.4	-0.4	-0.1	0.2	0.7	0.3	0.6	0.0	-0.1
Frequency of tiredness / lethargy in last 2 weeks	0.9	1.5	3.1	-0.7	-1.7	-1.6	1.8	0.6	1.6	0.9	0.2	-0.7
Falls in the last year	0.7	0.9	2.0	0.9	1.3	0.6	-1.1	-0.5	-1.0	-1.0	-1.4	-0.6
Hair/balding pattern: Pattern 3	0.5	0.8	3.8	-2.0	0.1	-0.2	-0.2	-0.4	0.5	-0.9	1.4	-0.5
Number of live births	0.5	0.7	1.7	-0.5	-1.3	-1.2	1.2	0.4	0.6	0.5	-0.4	-0.3
Forced expiratory volume in 1-second (FEV1)	1.0	3.4	10.6	-0.1	-0.6	-3.3	3.0	1.8	-0.2	1.5	1.4	1.8
Pulse rate	11.8	19.9	48.7	-5.1	1.2	2.6	-3.1	-6.0	-1.4	-6.4	-2.8	-7.0
Happiness	1.2	1.4	5.1	-1.5	-2.3	-0.1	0.6	-0.1	2.0	0.4	-0.7	-0.7
Noisy workplace	0.2	0.2	0.8	0.1	0.7	0.4	-0.6	-0.0	0.2	-0.9	0.2	0.3
Qualifications: A levels/AS levels or equivalent	2.4	5.2	12.0	2.3	0.8	-3.5	2.9	1.4	-2.9	1.1	2.0	2.4
Serious illness, injury or assault of a close relative in last 2 years	2.8	3.2	15.8	-4.0	0.6	0.5	-0.5	-1.0	-0.7	-0.9	2.8	-1.2
Mouth/teeth dental problems: Dentures	3.2	5.5	10.3	-2.8	-1.5	3.2	-2.5	-3.2	1.6	-1.0	-2.0	-2.1
Asthma	0.4	0.7	2.5	0.3	0.0	-0.9	0.7	1.2	0.3	0.6	0.9	1.6
Medication: Ibuprofen (e.g. Nurofen)	1.5	1.9	5.4	-2.3	-0.2	0.4	-0.8	-1.4	-0.3	-1.6	-2.0	-1.4
Medication: Cholesterol lowering	2.3	3.5	9.3	-1.1	-0.3	1.7	-1.1	-3.0	-0.1	-2.2	-1.6	-3.0
Depression (self-reported)	0.3	0.4	1.5	-0.1	-0.3	-0.6	0.6	0.7	0.4	1.2	-0.9	0.2
Medication: Lansoprazole	2.6	2.9	5.7	-2.0	-0.6	1.6	-1.8	-2.4	1.7	-1.9	-0.6	-1.9
Prospective memory result	0.6	0.8	4.0	0.7	0.0	0.4	-0.3	1.2	-0.0	-0.0	-0.9	2.0
Lung cancer (father)	0.4	0.5	1.5	-0.5	0.8	0.1	-0.2	-0.4	-0.7	-0.6	-0.8	-1.2
Illnesses of mother	0.5	0.6	2.1	-1.1	-0.4	-0.6	0.5	-1.5	-0.1	-1.0	-0.1	-0.5
Forced expiratory volume in 1-second (FEV1), Best measure	0.6	2.0	6.7	-0.1	-0.2	-2.6	2.1	1.4	0.1	1.1	1.4	1.3
Pulse wave Arterial Stiffness index	0.6	0.7	1.6	-0.9	0.1	0.9	-0.6	-1.3	0.4	-0.8	0.6	-1.2
Impedance of arm (left)	0.4	1.9	3.8	-0.5	-1.5	1.8	-1.2	-1.4	1.5	-1.2	0.1	-1.9
Arm fat mass (right)	3.0	12.2	25.1	-3.2	2.1	4.6	-5.0	-3.6	0.1	-4.5	-3.3	-2.4
Trunk predicted mass	0.4	2.3	6.4	0.8	2.2	1.2	-1.7	1.0	-0.8	-0.8	-1.6	2.5
Standing height	0.4	4.3	10.3	1.7	2.0	2.8	-3.1	1.9	0.1	-0.7	-0.5	3.2
Length of working week for main job	0.7	0.8	2.3	-1.5	-0.3	0.7	-0.8	0.0	0.7	-0.8	1.5	0.4
Exposure to tobacco smoke at home	0.3	0.3	1.2	-0.1	1.1	-0.3	-0.1	-0.9	-0.1	0.2	0.3	-0.8
Breastfed as a baby	2.0	2.5	10.7	3.3	1.4	-0.5	0.2	0.5	-2.0	0.5	1.6	1.5
Tense / ‘highly strung’	0.4	0.6	1.3	-0.8	-0.4	-1.1	1.1	-0.3	0.6	0.8	0.9	-0.4
Seen doctor (GP) for nerves, anxiety, tension or depression	0.6	1.0	3.8	0.6	-0.6	-0.3	0.7	1.2	0.3	2.0	-0.6	1.3
Hair/balding pattern: Pattern 4	0.8	2.1	5.0	-1.0	1.7	1.4	-1.5	-2.2	-0.6	-1.3	-0.5	-1.8
Birth weight of first child	1.6	2.8	8.3	1.1	-1.0	-2.6	2.9	1.6	-0.9	1.7	0.7	1.2
Peak expiratory flow (PEF)	0.3	0.8	2.2	-0.6	0.9	-1.5	0.9	0.5	-0.6	0.5	0.7	1.3
Pulse wave reflection index	1.4	1.7	4.6	1.3	-0.1	-0.2	0.9	1.8	0.9	1.6	1.4	2.1
Ever highly irritable/argumentative for 2 days	1.3	1.5	6.6	-2.6	-0.9	0.1	0.1	-1.3	1.5	-0.3	0.9	-1.2
Loud music exposure frequency	0.4	0.5	1.5	-0.4	0.1	-0.2	0.3	-1.1	0.6	-0.9	-0.3	-1.2
Qualifications: O levels/GCSEs or equivalent	1.6	2.6	6.0	0.3	-1.2	-2.4	2.3	1.8	-0.3	2.1	1.2	1.2
Mouth/teeth dental problems: Bleeding gums	0.4	0.5	2.3	0.8	-0.0	-0.1	0.1	1.2	-0.1	0.6	-0.2	1.5
Blood clot in the leg (DVT)	1.3	1.6	6.1	1.3	0.8	1.1	-1.4	1.1	-0.3	1.1	-0.8	2.5
Medication: Paracetamol	1.6	2.7	10.2	-1.4	0.1	0.7	-0.8	-2.6	-0.3	-1.8	-1.0	-3.2
Headache pain in last month	2.5	4.3	10.7	-1.4	0.4	1.8	-1.7	-3.2	-0.9	-2.5	-1.6	-3.3
Medication for cholesterol, blood pressure or diabetes	1.4	2.4	5.2	-0.6	-1.1	-1.8	1.6	2.3	1.0	1.7	1.2	1.8
Glaucoma (self-reported)	1.3	1.6	7.0	-2.6	0.9	-0.4	-0.4	-0.7	-1.6	-0.9	1.4	-0.6
Gout (self-reported)	1.6	2.1	6.0	1.0	-1.7	1.7	-1.0	0.1	2.3	-0.2	-2.4	0.5
Hypothyroidism/myxoedema (self-reported)	0.8	1.5	5.0	-1.5	1.1	-0.4	-0.3	-0.9	-2.2	-1.7	0.7	-1.0
Medication: Amlodipine	0.7	1.0	3.5	1.9	1.0	-0.1	-0.3	0.9	-1.1	0.5	-0.1	1.4
Medication: Ventolin 100micrograms inhaler	1.2	1.5	3.7	1.0	1.4	1.8	-1.9	0.6	0.2	-1.0	-0.6	1.4
Birth weight	0.6	1.2	3.4	0.7	-0.7	-0.3	0.6	1.3	0.4	1.5	1.8	1.4
Chronic bronchitis/emphysema (mother)	0.5	0.5	1.4	0.4	0.0	0.8	-0.7	0.8	1.2	0.3	-0.4	1.1
High blood pressure (siblings)	0.8	1.2	3.7	-1.0	0.0	1.1	-1.3	-1.0	0.1	-1.9	-0.0	-1.4
Forced vital capacity (FVC), Best measure	0.6	2.1	4.2	0.9	0.6	-2.0	1.3	2.0	-0.1	0.9	1.7	2.0
Body fat percentage	4.7	18.7	35.3	-4.4	1.8	5.6	-5.9	-4.8	0.9	-5.5	-3.1	-4.0
Leg fat percentage (right)	4.8	17.3	29.8	-4.7	1.7	4.2	-4.7	-5.5	0.5	-5.2	-3.4	-4.7
Arm fat-free mass (right)	0.7	3.8	9.5	-0.2	2.9	2.3	-3.1	0.0	-1.1	-1.7	-1.9	1.9
Exposure to tobacco smoke outside home	0.3	0.4	2.2	-1.5	-0.0	-0.1	-0.2	0.1	0.4	-0.3	0.8	-0.9
Comparative body size at age 10	0.5	1.3	7.3	0.5	-1.1	-0.1	0.4	-1.6	0.1	-0.6	-2.7	-0.6
Number of full brothers	0.6	0.7	2.2	-1.2	0.2	0.6	-0.6	-1.5	-0.5	-0.5	0.8	-0.9
Worry too long after embarrassment	0.6	1.1	4.5	2.1	-0.5	-0.2	0.4	1.0	-0.1	0.9	-1.3	1.0
Seen a psychiatrist for nerves, anxiety, tension or depression	1.9	2.5	11.1	0.4	-1.7	0.0	0.5	1.9	1.2	3.3	-0.0	1.7
Wheeze or whistling in the chest in last year	0.6	1.1	2.6	0.2	1.4	1.1	-1.1	-0.9	0.1	-1.6	-1.4	-0.7
Number of children fathered	0.3	0.3	1.0	0.7	0.4	0.1	0.1	-0.2	-0.7	-0.9	-1.0	0.1
Reason for reducing amount of alcohol drunk: Health precaution	3.1	3.6	7.7	2.4	-1.9	-0.6	1.5	2.5	1.1	2.8	-0.9	2.1
Age at first live birth	3.7	6.5	18.0	4.2	0.2	-1.3	1.5	3.8	-1.2	3.0	1.1	3.2
Pulse wave peak to peak time	0.7	0.9	2.4	0.9	-0.1	-0.8	0.6	1.6	-0.2	1.0	-0.5	1.5
Health satisfaction	2.6	3.4	6.2	-2.4	-0.8	1.6	-1.6	-2.5	0.7	-1.9	-1.8	-2.5
Shortness of breath walking on level ground	0.8	0.9	2.0	-1.4	-0.1	0.2	-0.7	-1.4	0.4	-1.1	-1.3	-0.6
Qualifications: College or University degree	2.8	8.8	16.7	2.3	-0.6	-2.9	3.1	4.1	-0.9	3.8	2.9	3.9
Eye problems/disorders: None of the above	0.5	0.6	1.8	0.0	-0.7	-0.8	1.1	0.8	1.3	0.7	-0.4	0.3
Mouth/teeth dental problems: Loose teeth	0.4	0.5	1.7	-0.9	-0.7	0.2	-0.2	-1.3	0.5	-1.0	-0.2	-0.2
Emphysema/chronic bronchitis	1.4	1.6	6.4	-0.0	1.0	0.4	-0.9	-2.5	-0.2	-1.5	-1.0	-1.6
Medication for pain relief, constipation, heartburn	2.4	4.2	10.5	2.1	-0.5	-1.6	1.9	2.6	0.5	2.4	1.7	3.2
Neck or shoulder pain in last month	1.0	1.4	3.2	-0.1	-1.1	-1.8	1.8	0.9	-0.2	1.8	0.8	0.1
Medication: Blood pressure	1.0	1.7	3.7	1.8	1.9	1.2	-1.3	-1.1	-1.5	-1.1	-0.4	-1.0
Angina (self-reported)	0.8	1.0	3.6	-1.9	1.2	0.1	-0.4	-0.5	-0.8	-1.0	-0.9	-1.2
Migraine (self-reported)	1.5	1.9	4.9	-0.6	0.4	1.8	-1.5	-2.2	-0.0	-1.1	-0.7	-2.2
Medication: Ibuprofen	1.6	2.0	4.6	-2.1	0.5	0.7	-1.1	-1.5	-0.6	-1.4	-1.6	-2.0
Medication: Allopurinol	2.2	2.9	7.3	0.5	-1.6	2.4	-1.8	-0.5	2.7	-0.7	-2.4	0.0
Medication: Omeprazole	0.5	0.6	2.5	-1.6	-0.6	0.5	-0.5	-0.1	0.4	0.1	1.0	-0.8
Medication: Seretide 50 evohaler	1.5	1.7	7.2	-0.5	0.3	-1.7	1.2	1.6	-0.9	-0.0	-0.2	2.7
Mean time to correctly identify matches	0.6	1.1	4.5	-1.0	-1.9	0.6	-0.7	0.0	2.1	-0.4	-0.1	-0.0
Heart disease (mother)	0.3	0.4	0.8	-0.7	-0.7	0.2	0.0	-0.7	-0.4	-0.4	-0.8	-0.9
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.0	1.2	2.9	-1.2	-0.0	-1.7	1.3	-0.1	-1.2	-1.1	1.3	-0.2
Whole body fat mass	3.8	15.8	35.2	-3.7	2.2	5.6	-5.9	-3.8	0.9	-4.9	-3.4	-2.5
Leg fat mass (right)	3.9	15.2	27.7	-3.9	2.5	4.7	-5.3	-4.4	0.1	-5.0	-3.6	-3.0
Arm predicted mass (right)	0.7	3.4	8.5	-0.1	2.8	2.3	-2.9	0.0	-1.0	-1.6	-1.7	1.7
Pulse rate, automated reading	18.5	59.7	127.7	-9.2	3.4	4.2	-5.9	-10.7	-4.0	-11.3	-2.9	-11.1
Alcohol intake frequency.	2.1	4.9	14.4	-1.5	0.8	1.6	-1.9	-3.8	-0.8	-3.0	-1.0	-3.1
Comparative height size at age 10	0.3	1.6	5.7	0.2	-0.2	1.6	-1.1	1.2	1.8	-0.3	0.4	2.4
Number of full sisters	1.7	2.1	6.2	-1.8	2.5	1.2	-1.1	-0.4	-1.4	-1.9	0.3	-0.9
Suffer from ‘nerves’	0.5	0.9	2.8	-0.1	-1.3	-0.3	0.8	0.8	1.7	1.2	0.1	-0.6
Overall health rating	1.9	4.1	13.5	-3.7	0.2	1.2	-1.4	-2.4	0.1	-2.5	-0.8	-2.7
Chest pain or discomfort	0.5	0.7	3.6	-1.9	-0.1	0.0	-0.1	-0.9	-0.4	-0.5	0.3	-1.2
Had major operations	1.0	1.2	3.7	-1.5	1.0	-0.0	-0.4	-0.6	-1.9	-1.2	1.2	-0.8
Age at last live birth	1.2	1.8	7.6	2.8	-0.4	-0.5	0.5	1.9	-0.1	1.5	0.2	1.4
Family relationship satisfaction	0.6	0.7	3.2	-0.2	-1.5	0.5	0.0	0.1	1.8	0.2	-0.2	-0.5
Leg pain on walking	0.6	0.8	2.6	-1.1	-0.6	-0.2	-0.1	-1.6	-0.3	-1.1	0.0	-1.3
Qualifications: NVQ or HND or HNC or equivalent	0.9	1.1	2.9	-1.3	1.7	0.5	-1.1	-1.5	-0.3	-0.9	-0.2	-0.7
Commuting to job workplace: Car/motor vehicle	1.1	1.3	3.5	-0.6	0.4	1.9	-1.7	-0.8	1.3	-1.2	-0.8	-0.2
Illness, injury, bereavement, stress in last 2 years	1.3	1.6	5.0	2.2	-0.2	1.0	-1.1	-1.6	0.6	-1.1	-1.3	-1.0
Medication: Aspirin	0.3	0.4	2.2	0.3	-0.4	0.7	-0.2	-0.2	0.1	0.2	-1.5	-0.4
Supplements: Vitamin C	0.7	0.9	2.3	0.7	0.2	-0.6	0.4	1.5	0.4	1.3	1.4	0.7
Knee pain experienced in last month	2.2	3.4	6.8	-2.6	0.2	2.5	-2.6	-1.6	0.6	-1.8	-1.3	-1.6
Hypertension (Self-reported)	0.4	1.0	2.5	0.5	0.8	1.6	-1.5	-0.6	-1.2	-0.9	-0.8	-0.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.7	0.9	2.1	-0.4	-0.6	1.2	-0.9	-1.3	0.1	-0.9	0.7	-1.4
Illnesses of father: Heart disease	1.0	1.3	2.6	1.1	-0.1	1.1	-1.3	1.0	0.1	1.4	1.4	1.6
Illnesses of siblings: Diabetes	3.0	3.7	6.8	-1.2	1.5	2.6	-2.2	-1.7	-1.5	-2.5	-1.8	-1.9
Smoking status: Previous	0.6	0.9	3.1	-1.2	0.2	0.9	-1.0	-1.8	0.0	-0.9	-0.2	-1.1
Forced expiratory volume in 1-second (FEV1), predicted	0.6	1.3	5.8	1.3	0.1	0.9	-0.8	1.3	0.9	0.7	0.0	2.4
Whole body fat-free mass	0.6	3.4	6.9	0.4	2.6	2.0	-2.6	0.6	-0.8	-1.4	-1.9	2.5
Leg fat-free mass (right)	0.8	4.5	11.0	-0.0	2.9	2.7	-3.3	0.2	-0.8	-2.0	-2.0	2.3
Arm fat percentage (left)	4.0	15.8	26.7	-4.0	1.7	4.8	-5.1	-4.7	0.2	-5.2	-3.5	-3.6
Average weekly red wine intake	6.2	9.1	20.3	0.2	-1.9	-0.9	1.7	4.5	2.6	4.4	4.2	3.2
Handedness (chirality/laterality): Left-handed	0.4	0.5	1.3	1.1	0.5	-0.7	0.6	0.8	0.3	0.2	1.1	0.1
Mood swings	0.7	1.3	4.3	-1.5	-0.4	0.2	-0.1	-1.4	0.3	-1.5	-1.1	-2.1
Loneliness, isolation	1.0	1.4	6.5	-1.2	-0.3	0.1	0.2	-1.4	0.8	-1.1	-0.8	-2.5
Long-standing illness, disability or infirmity	1.3	1.9	3.8	-1.3	1.2	0.7	-1.2	-1.9	-1.5	-1.6	0.4	-1.8
Ever had bowel cancer screening	0.3	0.3	0.9	0.7	0.2	0.8	-0.9	-0.5	0.0	-0.3	-0.7	-0.3
Diabetes diagnosed by doctor	2.1	3.5	8.7	-1.4	0.3	1.4	-1.4	-3.0	0.2	-2.9	-1.3	-2.5
Ever had stillbirth, spontaneous miscarriage or termination	1.2	1.3	2.8	-1.6	-0.8	-0.9	1.2	1.7	1.2	0.5	-0.4	1.2
Friendships satisfaction	1.3	1.6	6.4	-1.0	-2.5	-0.7	1.2	0.6	1.9	1.1	-0.6	0.2
Qualifications: nursing, teaching	3.3	5.1	12.8	1.0	-0.3	-3.2	2.8	2.7	-0.8	0.9	3.6	2.2
Commuting to job workplace: Walk	0.6	0.7	1.6	0.2	0.0	-1.1	0.8	0.7	-1.2	1.3	-0.1	0.8
Eye problems/disorders: Cataract	0.5	0.5	2.4	1.6	0.1	0.3	-0.2	-0.2	-1.0	0.1	-1.0	0.5
Mouth/teeth dental problems: Mouth ulcers	0.9	1.5	3.8	1.7	0.2	1.8	-1.2	-1.1	0.3	-0.2	-0.8	-2.0
Medication for cholesterol	2.1	3.1	6.2	1.8	0.0	-1.8	1.8	2.3	-0.0	2.2	1.6	2.5
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.5	0.6	1.5	0.8	0.8	1.2	-1.2	0.6	-0.5	-0.0	-0.8	0.3
Back pain experienced in last month	0.6	0.8	2.3	-0.2	-0.6	-1.4	1.5	0.2	-0.8	0.8	1.2	-0.3
Mineral and other dietary supplements	0.9	1.3	6.1	-2.5	-0.2	1.5	-1.1	-0.8	0.7	-0.8	-0.2	0.2
Breast cancer (self-reported)	1.0	1.2	2.9	-0.9	1.4	-1.1	0.3	0.7	-1.6	-0.0	1.7	1.2
Asthma (self-reported)	0.4	0.7	3.2	0.2	0.1	-0.7	0.5	1.2	0.4	0.5	0.8	1.8
Osteoporosis (self-reported)	1.2	1.5	8.3	2.9	0.4	0.3	-0.1	1.1	-0.9	1.5	-0.3	0.9
Osteoarthritis (self-reported)	0.9	1.2	3.4	-0.9	0.3	0.7	-1.0	-1.8	0.4	-1.8	-0.7	-1.1
Medication: Aspirin	0.3	0.4	1.4	-0.1	-0.1	0.6	-0.2	-0.9	-0.2	-0.2	-1.2	-1.1
Medication: Gliclazide	0.7	0.8	2.2	-1.5	-0.2	0.4	-0.7	-1.3	0.1	-1.1	0.3	-1.0
Illnesses of father: None of the above (group 1)	1.0	1.3	3.2	-0.6	-0.6	-1.3	1.7	1.4	0.0	0.8	-0.6	1.8
Smoking status: Current	0.8	1.2	4.2	-1.3	-0.5	0.8	-0.5	1.1	2.0	0.8	-0.9	1.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.1	2.4	10.9	-0.1	0.8	-3.3	2.5	0.3	-1.8	0.2	0.6	-0.0
Whole body water mass	0.6	3.4	7.3	0.5	2.7	1.9	-2.5	0.6	-0.9	-1.5	-1.9	2.4
Leg predicted mass (right)	0.9	4.7	11.4	0.1	3.0	2.8	-3.4	0.2	-0.8	-2.0	-2.1	2.3
Arm fat mass (left)	3.3	13.5	27.2	-3.3	2.3	4.7	-5.2	-3.8	0.0	-4.9	-3.5	-2.4
Number of self-reported non-cancer illnesses	1.9	3.2	6.5	-0.8	1.1	2.5	-2.5	-2.5	-0.5	-1.6	-1.3	-2.0
Average weekly champagne plus white wine intake	0.9	1.2	3.2	-0.7	-0.3	-1.7	1.8	1.4	-1.3	0.3	0.4	0.4
Miserableness	0.7	1.2	4.9	-0.9	-0.4	-2.2	1.9	0.8	-0.6	0.0	-0.6	-0.0
Guilty feelings	1.6	2.4	8.8	-0.0	2.8	-1.4	0.3	0.4	-3.0	-1.4	-0.7	0.6
Wears glasses or contact lenses	2.9	3.4	6.7	-2.4	0.1	1.7	-2.3	-1.9	0.3	-2.6	1.0	-2.2
Ever taken oral contraceptive pill	1.1	1.2	2.9	-1.0	-1.3	-0.1	0.3	1.7	1.2	1.0	0.7	1.5
Hearing aid user	2.6	3.0	7.1	-2.7	1.4	1.6	-1.6	-2.1	-1.3	-1.3	0.8	-2.0
Mother’s age at death	2.6	3.3	6.1	2.5	-0.4	2.0	-1.7	1.6	2.2	2.4	0.6	1.5
Financial situation satisfaction	1.5	1.8	7.0	-1.5	-2.6	0.3	0.6	0.5	2.2	0.4	-1.1	-0.7
Tinnitus: Yes, now most or all of the time	1.3	1.5	3.8	-1.6	-0.3	1.1	-1.0	-1.9	0.3	-0.6	-1.5	-1.4
Commuting to job workplace: Public transport	0.9	1.0	3.2	-0.3	-1.2	-1.6	1.8	0.2	0.2	1.0	0.9	-0.6
Eye problems/disorders: Glaucoma	1.2	1.4	9.4	-3.1	0.1	0.1	-0.6	-0.1	-0.5	0.1	1.5	-0.0
Medication: Blood pressure	0.8	1.6	3.7	-1.9	0.4	0.8	-1.1	-1.3	-0.7	-1.9	-1.3	-0.9
Pain type(s) experienced in last month: Hip pain	0.3	0.4	1.0	-1.0	-0.4	0.9	-0.7	0.2	-0.4	-0.8	0.1	-0.2
Supplements: Fish oil (including cod liver oil)	0.9	1.2	5.4	2.3	0.3	-1.3	1.0	0.6	-1.0	0.6	0.9	-0.1
High cholesterol (Self-reported)	1.0	1.8	3.9	-2.0	-0.5	1.8	-1.3	-1.4	0.1	-1.1	-1.2	-1.6
Medication: Bendroflumethiazide	0.4	0.7	2.2	-1.5	-0.1	-0.8	0.7	-0.7	-0.8	-0.8	0.1	-1.0
Medication: Paracetamol	2.5	3.9	16.2	-2.2	0.0	0.9	-1.0	-2.8	-0.0	-1.9	-0.4	-4.0
Medication: Lisinopril	1.6	2.0	7.4	-1.6	0.1	1.2	-1.0	-1.9	0.4	-1.3	-0.2	-2.7
Medication: Atorvastatin	0.6	0.8	1.9	-1.0	0.2	1.4	-1.2	-0.9	-0.2	-0.3	0.1	-1.4
Illnesses of father: High blood pressure	1.8	2.3	6.8	0.1	0.9	1.2	-1.4	-2.2	-0.6	-1.8	-1.1	-2.6
Alcohol drinker status: Never	0.6	0.7	1.7	0.4	1.3	0.4	-0.7	-0.5	-0.9	-1.3	0.7	-0.9
Ever smoked	0.7	1.2	4.3	-2.1	-0.1	1.3	-1.5	-0.7	1.1	-0.7	0.3	-0.3
Basal metabolic rate	0.8	4.4	11.5	-0.4	2.7	2.7	-3.4	-0.2	-0.6	-2.2	-2.3	1.6
Leg fat percentage (left)	5.1	18.3	30.4	-4.9	1.9	4.5	-5.2	-5.5	0.7	-5.4	-2.7	-4.7
Arm fat-free mass (left)	0.7	3.5	8.4	0.1	2.7	2.2	-2.9	0.5	-0.7	-1.3	-1.7	2.2
Number of operations (self-reported)	2.2	3.3	8.3	-1.0	2.4	0.9	-1.8	-2.1	-2.9	-2.0	-0.4	-1.4
Average weekly beer plus cider intake	0.8	1.2	7.9	0.9	0.3	-0.5	0.0	-0.7	0.5	-0.7	-2.8	-0.2
Irritability	1.8	3.0	9.0	0.3	-0.9	-3.0	3.0	1.4	-0.2	2.2	1.1	0.6
Risk taking	0.3	0.4	2.1	-1.5	-0.2	-0.1	0.1	0.7	0.4	-0.0	0.7	0.2
Ever had prostate specific antigen (PSA) test	0.3	0.3	0.8	-0.8	0.0	0.4	-0.3	-0.9	-0.1	-0.5	-0.4	-0.7
Fractured/broken bones in last 5 years	0.9	1.2	2.4	-0.7	-0.7	-1.4	1.4	1.5	0.5	0.9	0.1	1.5
Age started oral contraceptive pill	1.2	1.6	4.4	2.0	-0.2	-0.2	0.5	1.6	-1.0	0.8	0.9	2.1
Diastolic blood pressure, automated reading	0.9	2.9	6.8	-2.6	1.7	1.1	-1.5	-1.8	-1.6	-2.4	-0.1	-1.0
Ever depressed for a whole week	0.9	1.1	3.1	-1.4	-0.7	1.3	-1.2	0.5	1.8	0.5	-0.8	0.8
Unable to work because of sickness or disability	0.7	0.9	2.2	-1.3	-1.5	1.1	-0.2	0.3	1.2	0.9	-0.2	-0.4
Commuting to job workplace: Cycle	1.4	1.6	7.0	1.2	0.8	-2.6	1.8	0.6	-1.2	0.2	0.4	0.6
Myopia	0.3	0.5	1.3	-0.8	0.9	-1.2	0.3	0.4	-0.2	-1.1	-0.1	-0.2
Vascular/heart problems diagnosed by doctor	0.5	1.5	3.1	-0.6	-1.4	-1.8	1.8	0.5	1.5	0.8	1.2	0.2
Cholesterol lowering medication	2.0	2.9	4.7	-1.7	1.3	1.8	-2.1	-1.9	-0.8	-1.9	-2.2	-1.2
Medication: Omeprazole (e.g. Zanprol)	0.4	0.5	2.5	-1.6	-0.4	0.3	-0.4	-0.5	0.4	0.0	0.7	-1.0
Pain experienced in last month	0.8	1.3	2.4	1.5	-1.0	-0.9	1.3	1.3	1.1	1.4	0.4	0.9
Supplements: Calcium	1.9	2.1	8.1	2.9	0.1	0.1	0.2	1.8	0.3	2.1	0.5	1.6
Basal cell carcinoma (self-reported)	0.7	0.8	2.4	-0.2	0.9	0.3	-0.7	-0.4	-1.2	-1.6	1.3	-0.8
Heart attack/myocardial infarction (self-reported)	1.5	1.9	6.7	-1.0	1.6	0.2	-0.7	-1.9	-1.0	-2.6	-0.7	-1.0
Deep venous thrombosis (DVT) (self-reported)	1.4	1.8	7.3	1.3	0.9	1.1	-1.5	1.1	-0.5	1.0	-0.6	2.7
Heart disease (siblings)	0.3	0.4	1.1	-0.2	0.2	-0.7	0.8	-0.1	-0.9	-1.1	-0.8	-0.1
Alcohol drinker status: Previous	0.8	0.9	2.1	-1.4	-1.0	-0.6	0.6	0.4	0.3	1.4	1.4	-0.2
Pack years of smoking	0.7	1.0	3.2	-1.8	-0.3	1.0	-0.6	-0.7	-0.3	-0.7	-1.8	-0.1
Impedance of whole body	0.5	2.3	7.3	-1.2	-1.3	1.4	-1.1	-1.6	1.6	-1.3	0.9	-2.7
Leg fat mass (left)	3.8	14.7	29.1	-3.9	2.5	4.8	-5.4	-4.1	0.3	-4.9	-3.3	-2.8
Arm predicted mass (left)	0.7	3.5	9.0	0.1	2.9	2.3	-3.0	0.3	-0.8	-1.5	-1.5	2.0