TWAS hub - ADPGK-AS1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Spleen	0.337	0.117	0.0056	-0.001	NA	-0.002	NA	-0.003	0.3500	NA	0.37	NA	0.380
2	GTEx	Testis	0.171	0.063	0.0014	0.051	NA	0.012	NA	0.033	0.0028	NA	0.09	NA	0.013

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Leg fat percentage (left)	5.8	20.8	41.3	-0.5	6.4
Leg fat percentage (right)	5.4	19.7	39.0	-0.6	6.2
Body fat percentage	4.9	19.4	38.7	-0.2	6.2
Leg fat mass (right)	4.7	18.3	36.7	0.1	6.1
Leg fat mass (left)	4.6	18.1	36.2	0.2	6.0
Qualifications: A levels/AS levels or equivalent	4.5	9.9	14.4	2.3	-3.8
Trunk fat percentage	4.2	16.8	33.5	0.0	5.8
Whole body fat mass	4.2	17.5	35.1	0.1	5.9
Arm fat percentage (left)	4.2	16.8	33.6	0.2	5.8
Wears glasses or contact lenses	4.1	4.7	6.6	1.7	2.6
Arm fat percentage (right)	4.0	15.8	31.7	0.1	5.6
Breastfed as a baby	3.7	4.6	8.0	1.1	-2.8
Trunk fat mass	3.6	15.4	30.8	0.2	5.5
Health satisfaction	3.6	4.6	6.9	-1.5	2.6
Arm fat mass (left)	3.6	15.0	29.8	0.4	5.5
Serious illness, injury or assault to yourself	3.5	4.2	6.5	2.5	-1.4
Qualifications: nursing, teaching	3.5	5.4	7.6	2.8	-1.8
Multivitamins +/- minerals	3.3	4.1	4.3	-2.1	-2.0
Arm fat mass (right)	3.3	13.7	27.3	0.2	5.2
Pulse rate	3.2	5.4	10.7	-0.1	3.3
Hip circumference	3.1	13.3	25.2	1.2	5.0
Triglycerides	3.0	4.9	5.1	2.2	2.3
Average weekly fortified wine intake	3.0	3.5	5.5	-1.3	-2.3
Waist circumference	2.9	10.7	21.1	0.4	4.6
Medication: Atorvastatin	2.9	3.6	3.7	1.9	1.9
BMI	2.8	16.2	29.9	1.6	5.5
Vitamin and mineral supplements	2.8	3.8	6.5	1.1	2.5
Alcohol usually taken with meals	2.8	4.5	4.5	2.1	-2.1
Medication: Allopurinol	2.8	3.7	4.2	-1.8	2.1
Body mass index (BMI)	2.7	11.5	22.7	0.6	4.8
Commuting to job workplace: Car/motor vehicle	2.7	3.1	4.4	-1.3	2.1
Knee pain experienced in last month	2.7	4.1	8.2	-0.1	2.9
Forced expiratory volume in 1-second (FEV1), predicted percentage	2.7	5.8	11.2	-0.6	-3.4
Emphysema/chronic bronchitis	2.6	2.9	4.4	-2.1	1.2
Birth weight of first child	2.5	4.5	8.5	0.6	-2.9
Chronic bronchitis/emphysema (father)	2.4	2.8	4.6	2.1	-1.0
Mouth/teeth dental problems: Dentures	2.3	3.9	6.7	1.1	2.6
Family relationship satisfaction	2.3	2.8	5.7	-2.4	-0.0
Loneliness, isolation	2.2	3.1	6.2	-2.5	-0.2
Diabetes (father)	2.1	2.6	3.9	-2.0	1.1
Forced expiratory volume in 1-second (FEV1), Best measure	2.1	6.7	13.1	-0.5	-3.6
Qualifications: College or University degree	2.1	6.5	8.8	3.0	-2.1
Had menopause	2.0	2.5	4.9	2.2	-0.1
Mineral and other dietary supplements	1.9	2.6	4.0	2.0	1.1
Stomach or abdominal pain in last month	1.8	2.2	2.9	-1.7	1.2
Supplements: Glucosamine	1.8	2.3	4.1	-2.0	-0.7
Diverticular disease/diverticulitis (self-reported)	1.8	2.2	3.8	0.7	2.0
Medication: Atenolol	1.8	2.3	3.3	1.8	1.1
Weight	1.8	8.9	17.5	0.7	4.2
Forced expiratory volume in 1-second (FEV1)	1.8	6.2	12.1	-0.6	-3.5
Supplements: Fish oil (including cod liver oil)	1.8	2.3	2.9	-1.4	-1.7
Irritability	1.8	3.1	6.0	-0.4	-2.4
Body Mass Index (BMI) (2010)	1.7	2.3	4.6	0.1	2.1
Fed-up feelings	1.7	3.1	4.7	-2.2	-1.2
Friendships satisfaction	1.7	2.1	3.2	-1.8	1.0
Back pain experienced in last month	1.7	2.5	3.7	1.9	-1.1
Alzheimer’s Disease (in mother)	1.6	1.9	2.3	-1.3	-1.5
Lung FVC	1.6	8.3	12.4	-2.1	-3.5
Peak expiratory flow (PEF)	1.6	3.7	7.4	0.1	-2.7
Wheeze or whistling in the chest in last year	1.6	2.8	4.0	-1.3	2.0
Supplements: Vitamin C	1.6	1.9	3.6	0.5	-1.9
Average weekly red wine intake	1.6	2.4	3.8	1.9	-1.0
Tinnitus: Yes, now most or all of the time	1.6	1.9	3.8	-0.1	1.9
Heel bone mineral density (BMD) T-score, automated (left)	1.5	3.3	5.6	1.0	-2.4
Length of working week for main job	1.5	1.7	2.8	1.7	0.7
Gout (self-reported)	1.5	2.0	2.4	-1.3	1.6
Forced vital capacity (FVC), Best measure	1.5	5.6	11.0	-0.5	-3.3
Pulse rate, automated reading	1.5	4.9	9.2	0.8	3.0
Breast cancer (self-reported)	1.5	1.8	3.2	1.8	-0.7
Miserableness	1.5	2.6	2.8	-1.5	-1.7
Depressed Affect (Nagel 2018)	1.4	3.0	5.0	-2.2	-1.0
Neuroticism (Nagel 2018)	1.4	3.2	4.5	-2.1	-1.4
Loud music exposure frequency	1.4	1.5	3.0	-0.3	-1.7
Glaucoma (self-reported)	1.4	1.7	2.6	0.8	-1.6
Mean time to correctly identify matches	1.4	2.7	5.3	-0.0	2.3
Hearing difficulty/problems: Yes	1.3	2.0	3.6	0.6	1.9
Hair/balding pattern: Pattern 2	1.3	1.7	2.4	1.5	-1.0
Forced vital capacity (FVC)	1.3	5.1	9.7	-0.8	-3.1
Ever unenthusiastic/disinterested for a whole week	1.3	1.6	1.9	-1.4	1.1
Happiness	1.3	1.6	3.2	-1.8	0.1
Blood clot in the leg (DVT)	1.3	1.7	3.3	-0.4	1.8
Ever had stillbirth, spontaneous miscarriage or termination	1.3	1.4	2.6	0.4	-1.6
Pain experienced in last month	1.3	2.2	2.8	-1.2	-1.7
Supplements: Calcium	1.3	1.4	2.8	-0.2	-1.7
Depression (Nagel 2018)	1.2	1.9	3.2	-1.8	-0.7
Major Depression (MDD)	1.2	1.4	2.7	-0.3	1.7
Hand grip strength (left)	1.2	3.2	6.5	-0.1	-2.5
Nervous feelings	1.2	2.2	4.5	-2.1	0.1
Had other major operations	1.2	1.5	2.8	-0.5	1.7
Heel bone mineral density (BMD) T-score, automated (right)	1.2	2.9	5.0	0.9	-2.2
Ever highly irritable/argumentative for 2 days	1.2	1.4	2.1	-1.5	0.8
Medication: Ventolin 100micrograms inhaler	1.2	1.6	3.1	0.1	1.8
Overall health rating	1.2	2.5	4.8	-0.5	2.2
Diabetes diagnosed by doctor	1.2	2.0	3.7	-1.9	0.6
Illnesses of father: High blood pressure	1.2	1.5	2.9	-1.7	0.1
Commuting to job workplace: Cycle	1.2	1.4	2.8	-0.1	-1.7
Deep venous thrombosis (DVT) (self-reported)	1.2	1.5	2.9	-0.2	1.7
Medication: Lansoprazole	1.1	1.2	1.9	0.8	1.4
Age at first live birth	1.1	2.0	2.5	1.2	-1.6
Medication: Seretide 50 evohaler	1.1	1.2	1.9	0.8	1.4
Guilty feelings	1.1	1.6	2.9	-0.6	-1.7
Commuting to job workplace: Public transport	1.1	1.3	2.4	0.5	-1.5
Alcohol drinker status: Previous	1.1	1.3	2.5	1.6	-0.3
Fasting Glucose	1.0	1.2	2.3	-0.1	-1.5
HDL Cholesterol	1.0	1.7	2.0	-1.2	-1.4
Medication: Co-codamol	1.0	1.2	2.3	-0.2	1.5
Hayfever, allergic rhinitis or eczema	1.0	2.1	2.3	-1.5	-1.4
Pain all over the body in last month	1.0	1.1	1.8	0.7	1.3
Diabetes (self-reported)	1.0	1.6	3.0	-1.7	0.4
Neuroticism score	1.0	2.0	3.4	-1.8	-0.8
Illnesses of father: None of the above (group 1)	1.0	1.2	2.3	0.4	-1.5
Ovarian Cancer	0.9	1.3	1.3	-1.1	1.2
Waist Hip Ratio (WHR)	0.9	4.1	5.7	-2.4	-1.5
Hearing difficulty/problems with background noise	0.9	1.5	2.9	-0.1	1.7
Mouth/teeth dental problems	0.9	1.4	2.7	0.2	-1.7
Heart attack	0.9	1.1	1.7	-0.8	1.3
Qualifications: O levels/GCSEs or equivalent	0.9	1.4	2.6	0.5	-1.6
Worry too long after embarrassment	0.9	1.6	2.8	-0.6	-1.7
Commuting to job workplace: Walk	0.9	1.0	1.1	0.9	-1.1
Medication: Gliclazide	0.9	1.0	1.2	1.1	0.9
Medication: Bendroflumethiazide	0.9	1.4	1.9	0.9	-1.4
Alcohol drinker status: Never	0.9	1.1	1.9	1.4	0.4
Age started oral contraceptive pill	0.9	1.1	1.8	1.3	-0.7
Diastolic blood pressure, automated reading	0.9	2.7	4.6	2.1	0.9
Heart attack/myocardial infarction (self-reported)	0.9	1.1	1.6	-0.8	1.3
Type 2 Diabetes (T2D) (2012)	0.8	0.9	1.3	-0.8	1.1
Blood Red Count	0.8	8.0	13.7	3.7	1.5
Frequency of unenthusiasm / disinterest in last 2 weeks	0.8	1.0	2.0	-1.4	-0.2
Bilateral oophorectomy (both ovaries removed)	0.8	0.9	1.1	-0.9	1.0
High blood pressure	0.8	2.3	4.6	2.1	-0.2
Hayfever/allergic rhinitis (self-reported)	0.8	1.1	2.0	-1.4	-0.4
Illnesses of siblings	0.8	1.1	2.2	-1.5	0.3
Exposure to tobacco smoke at home	0.8	0.9	1.0	-1.0	0.9
Hair/balding pattern: Pattern 4	0.8	1.9	3.3	-0.7	1.8
Birth weight	0.8	1.8	3.6	1.9	0.0
Number of children fathered	0.8	1.0	1.3	-0.8	1.1
Medication: Omeprazole	0.8	0.9	1.8	0.1	1.4
Smoking status: Current	0.8	1.3	2.4	0.4	1.6
Ever taken oral contraceptive pill	0.8	0.9	1.8	1.3	0.2
Average weekly beer plus cider intake	0.8	1.2	1.8	-1.4	0.7
Reaction Time	0.7	1.3	2.6	0.0	1.6
Primary Biliary Cirrhosis	0.7	1.0	1.1	-0.9	-1.0
Rheumatoid Arthritis	0.7	1.0	1.3	1.1	-0.8
Allergy or Eczema	0.7	1.7	2.2	-1.1	-1.5
Hand grip strength (right)	0.7	1.8	3.6	0.2	-1.9
Qualifications: CSEs or equivalent	0.7	1.0	1.6	-1.3	0.5
Financial difficulties in last 2 years	0.7	1.0	1.9	-1.4	0.3
Impedance of arm (right)	0.7	3.1	6.1	-2.5	0.2
Hair/balding pattern: Pattern 3	0.7	1.1	2.0	-0.4	1.4
Medication: Ibuprofen (e.g. Nurofen)	0.7	0.9	1.5	1.2	-0.6
Suffer from ‘nerves’	0.7	1.1	2.1	-1.5	-0.1
Chest pain or discomfort	0.7	1.0	2.0	-0.2	1.4
Age at last live birth	0.7	1.1	1.7	0.6	-1.3
Mouth/teeth dental problems: Mouth ulcers	0.7	1.1	2.1	-1.4	0.2
Pain type(s) experienced in last month: Hip pain	0.7	0.9	1.7	0.1	1.3
Medication: Paracetamol	0.7	1.2	2.2	-0.3	1.5
Cholesterol lowering medication	0.7	1.0	1.1	1.0	1.0
Average weekly spirits intake	0.6	0.7	1.4	-0.2	-1.2
Frequency of depressed mood in last 2 weeks	0.6	0.9	1.6	-1.2	0.4
Age when periods started (menarche)	0.6	1.4	1.8	-1.0	1.3
Sitting height	0.6	4.0	4.9	1.8	-2.2
Alcohol intake versus 10 years previously	0.6	0.9	1.2	-1.1	0.7
Lung cancer (father)	0.6	0.7	1.3	-0.2	1.2
Exposure to tobacco smoke outside home	0.6	0.8	0.9	0.9	-0.9
Reason for reducing amount of alcohol drunk: Health precaution	0.6	0.6	0.7	0.8	-0.8
Medication for cholesterol	0.6	1.0	1.9	0.2	-1.4
Vascular/heart problems diagnosed by doctor	0.6	1.7	3.2	-1.8	-0.3
Prostate Cancer	0.5	0.7	1.2	1.1	-0.4
Mean Putamen Volume	0.5	0.6	0.8	0.9	-0.6
Respiratory disease	0.5	1.0	1.6	-0.7	1.3
Ever had hysterectomy (womb removed)	0.5	0.6	0.8	0.9	-0.6
Medication: Metformin	0.5	0.8	1.2	-0.5	1.1
Townsend deprivation index at recruitment	0.5	0.7	1.4	1.2	-0.2
Past tobacco smoking	0.5	0.9	1.9	0.0	-1.4
Qualifications: None of the above	0.5	1.1	1.6	-0.8	1.3
Medication: Simvastatin	0.5	0.7	1.0	-1.0	0.6
Time employed in main current job	0.5	0.6	0.8	0.6	-0.9
Medication: Paracetamol	0.5	0.8	1.4	-0.5	1.2
Medication: Ibuprofen	0.5	0.6	0.8	0.9	-0.6
Leg pain on walking	0.5	0.7	1.2	-0.4	-1.1
Illness, injury, bereavement, stress in last 2 years	0.5	0.6	1.0	-0.3	1.0
Hypertension (Self-reported)	0.5	1.3	2.5	1.6	-0.3
Average weekly champagne plus white wine intake	0.5	0.6	0.9	0.9	-0.6
Hearing aid user	0.5	0.6	0.8	0.6	0.9
Ever smoked	0.5	0.9	1.9	-0.1	1.4
LDL Cholesterol	0.4	0.7	1.1	1.0	0.6
Ulcerative Colitis	0.4	0.6	1.2	-0.2	-1.1
Cardiovascular Disease	0.4	1.4	1.9	1.4	1.0
Type 2 Diabetes (T2D) (2018)	0.4	0.7	1.4	-1.2	0.2
Neuroticism	0.4	1.0	1.3	-0.8	-1.2
Other serious medical condition/disability diagnosed by doctor	0.4	0.5	0.6	0.6	-0.7
Leg fat-free mass (left)	0.4	2.3	3.7	1.0	1.9
Current tobacco smoking	0.4	0.6	1.2	-0.1	1.1
Relative age voice broke	0.4	0.6	1.1	-0.3	1.1
High blood pressure (mother)	0.4	0.5	0.6	-0.8	-0.7
Impedance of leg (left)	0.4	1.9	3.2	-1.8	0.7
Leg predicted mass (left)	0.4	2.3	3.6	1.0	1.9
Asthma	0.4	0.7	1.3	0.3	1.1
Medication: Cholesterol lowering	0.4	0.6	1.0	-1.0	0.5
Prospective memory result	0.4	0.5	0.9	0.9	0.5
Tense / ‘highly strung’	0.4	0.7	1.0	-0.6	-1.0
Pulse wave reflection index	0.4	0.5	0.8	0.5	-0.9
Hypothyroidism/myxoedema (self-reported)	0.4	0.7	1.1	1.1	0.5
Arm fat-free mass (right)	0.4	1.9	2.4	1.5	1.2
Number of full brothers	0.4	0.5	0.9	0.3	-0.9
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.5	1.0	1.0	0.3
Medication: Blood pressure	0.4	0.7	1.1	0.6	-1.0
Heart disease (mother)	0.4	0.5	0.9	0.1	1.0
Long-standing illness, disability or infirmity	0.4	0.7	1.3	1.1	0.3
Ever had bowel cancer screening	0.4	0.5	0.5	-0.7	0.6
Asthma (self-reported)	0.4	0.7	1.3	0.5	1.1
Osteoarthritis (self-reported)	0.4	0.5	1.0	-0.3	1.0
Leg predicted mass (right)	0.4	1.9	2.9	1.0	1.7
Mother’s age at death	0.4	0.4	0.5	0.7	0.6
Basal metabolic rate	0.4	2.3	3.7	0.9	1.9
Arm fat-free mass (left)	0.4	2.2	2.3	1.4	1.5
Unable to work because of sickness or disability	0.4	0.5	0.8	0.4	0.9
Myopia	0.4	0.6	0.7	-0.7	-0.8
Medication: Omeprazole (e.g. Zanprol)	0.4	0.5	1.1	-0.0	1.0
Intelligence (Savage-Jansen 2018)	0.3	0.9	1.6	0.3	-1.3
Worry (Nagel 2018)	0.3	0.6	1.3	-1.1	-0.2
Alzheimer’s Disease (in father)	0.3	0.3	0.5	-0.2	0.7
Coronary Artery Disease (CAD)	0.3	0.4	0.7	0.8	-0.3
Lupus	0.3	0.4	0.8	-0.2	0.9
Blood Platelet Count	0.3	2.9	5.6	-2.4	0.5
Systolic Blood Pressure	0.3	1.7	2.7	0.8	-1.6
Chronotype (morning person)	0.3	0.8	1.1	0.6	1.1
Hair Pigment	0.3	8.2	13.0	3.6	-1.8
Sensitivity / hurt feelings	0.3	0.6	1.1	-1.0	-0.3
Systolic blood pressure, automated reading	0.3	0.9	1.7	0.4	-1.3
Medication for hormone replacement therapy	0.3	0.3	0.6	0.8	0.1
Impedance of leg (right)	0.3	1.6	3.1	-1.8	0.4
Maternal smoking around birth	0.3	0.5	0.5	0.7	0.6
Number of live births	0.3	0.4	0.6	-0.5	-0.8
Noisy workplace	0.3	0.4	0.7	0.9	-0.1
Serious illness, injury or assault of a close relative in last 2 years	0.3	0.4	0.6	0.4	-0.8
Impedance of arm (left)	0.3	1.5	2.7	-1.6	0.6
Mouth/teeth dental problems: Bleeding gums	0.3	0.4	0.8	0.0	-0.9
Migraine (self-reported)	0.3	0.4	0.6	-0.8	-0.2
Arm predicted mass (right)	0.3	1.7	2.2	1.5	1.1
Alcohol intake frequency.	0.3	0.6	0.9	1.0	0.5
Had major operations	0.3	0.3	0.4	0.6	-0.5
Illnesses of father: Heart disease	0.3	0.5	0.7	0.5	0.8
Leg fat-free mass (right)	0.3	1.9	2.6	1.1	1.6
Mood swings	0.3	0.5	1.0	-1.0	-0.3
Financial situation satisfaction	0.3	0.4	0.5	-0.7	0.5
High cholesterol (Self-reported)	0.3	0.6	0.7	0.7	0.9
Number of operations (self-reported)	0.3	0.4	0.5	0.7	0.5
Impedance of whole body	0.3	1.5	2.6	-1.6	0.6
Arm predicted mass (left)	0.3	1.7	1.8	1.3	1.3
Alzheimer’s Disease (including proxy)	0.2	0.3	0.4	-0.5	-0.6
Crohns Disease (2017)	0.2	0.4	0.7	0.9	-0.2
Neuroticism (2016)	0.2	0.3	0.6	-0.8	0.2
Smoking Status	0.2	0.5	0.8	-0.4	0.9
Relative age of first facial hair	0.2	0.5	1.0	0.1	1.0
Eye problems/disorders: Diabetes related eye disease	0.2	0.2	0.3	-0.4	0.5
Angina	0.2	0.3	0.4	0.5	0.6
Allergy	0.2	0.5	1.0	1.0	0.1
Fluid intelligence score	0.2	0.5	0.9	-1.0	0.2
Pulse wave Arterial Stiffness index	0.2	0.2	0.5	0.2	0.7
Medication: Amlodipine	0.2	0.2	0.5	0.7	0.1
High blood pressure (siblings)	0.2	0.3	0.4	0.5	0.6
Pulse wave peak to peak time	0.2	0.3	0.4	-0.4	-0.6
Shortness of breath walking on level ground	0.2	0.2	0.5	-0.0	0.7
Mouth/teeth dental problems: Loose teeth	0.2	0.2	0.4	-0.6	0.1
Comparative height size at age 10	0.2	0.8	1.6	0.3	-1.3
Medication: Aspirin	0.2	0.3	0.3	0.5	-0.5
Whole body fat-free mass	0.2	1.0	1.0	1.0	1.0
Handedness (chirality/laterality): Left-handed	0.2	0.2	0.3	-0.3	-0.6
Eye problems/disorders: Cataract	0.2	0.2	0.3	-0.5	-0.3
Medication: Aspirin	0.2	0.2	0.4	0.3	-0.6
Whole body water mass	0.2	1.0	1.0	1.0	0.9
Number of self-reported non-cancer illnesses	0.2	0.3	0.4	-0.5	0.7
Schizophrenia vs Biploar Disorder	0.1	0.1	0.1	0.4	0.3
Irritable Bowel Disease (IBD)	0.1	0.2	0.3	0.3	-0.6
Ulcerative Colitis (UC)	0.1	0.2	0.2	-0.5	-0.3
Verbal and Numeric Reasoning (VNR)	0.1	0.1	0.3	-0.2	-0.5
Breast Cancer	0.1	0.3	0.5	0.2	0.7
Age at First Birth	0.1	0.2	0.3	0.3	-0.6
Crohns Disease (2012)	0.1	0.1	0.2	0.0	-0.4
Schizophrenia (2014)	0.1	0.2	0.3	-0.5	-0.2
Blood Eosinophil Count	0.1	1.1	1.6	-1.2	0.8
Blood White Count	0.1	1.0	2.0	-0.0	1.4
Heel T-Score	0.1	0.9	1.7	0.1	-1.3
Height	0.1	1.3	2.5	-0.2	-1.6
Hypothyroidism (self reported)	0.1	0.3	0.4	0.7	0.3
Lung FEV1/FVC ratio	0.1	0.7	1.3	-0.2	-1.1
Supplements: Zinc	0.1	0.1	0.1	-0.3	0.2
Diabetes (mother)	0.1	0.2	0.3	-0.5	0.3
Severe depression (siblings)	0.1	0.1	0.2	-0.3	0.5
Pack years adult smoking proportion	0.1	0.1	0.2	0.2	0.4
Taking other prescription medications	0.1	0.1	0.2	0.1	0.5
Frequency of tenseness / restlessness in last 2 weeks	0.1	0.1	0.2	-0.5	-0.1
Medication: Ramipril	0.1	0.1	0.3	-0.1	-0.5
Trunk fat-free mass	0.1	0.5	1.0	1.0	0.2
Father’s age at death	0.1	0.1	0.1	-0.4	0.3
Frequency of tiredness / lethargy in last 2 weeks	0.1	0.2	0.3	-0.6	-0.2
Depression (self-reported)	0.1	0.1	0.2	-0.2	0.4
Illnesses of mother	0.1	0.1	0.1	0.4	0.1
Trunk predicted mass	0.1	0.5	0.9	1.0	0.2
Seen doctor (GP) for nerves, anxiety, tension or depression	0.1	0.1	0.1	0.4	-0.2
Headache pain in last month	0.1	0.1	0.2	-0.3	0.4
Chronic bronchitis/emphysema (mother)	0.1	0.1	0.1	0.3	-0.2
Comparative body size at age 10	0.1	0.4	0.7	-0.1	0.8
Medication for pain relief, constipation, heartburn	0.1	0.2	0.2	0.2	-0.5
Angina (self-reported)	0.1	0.2	0.3	0.1	0.6
Number of full sisters	0.1	0.1	0.2	-0.2	0.5
Qualifications: NVQ or HND or HNC or equivalent	0.1	0.2	0.3	-0.6	0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.1	0.1	0.1	0.2	0.3
Illnesses of siblings: Diabetes	0.1	0.1	0.2	0.1	0.5
Smoking status: Previous	0.1	0.2	0.2	-0.3	-0.4
Eye problems/disorders: Glaucoma	0.1	0.2	0.3	0.5	0.1
Medication: Blood pressure	0.1	0.1	0.3	0.1	0.5
Medication: Lisinopril	0.1	0.1	0.2	-0.1	0.5
Basal cell carcinoma (self-reported)	0.1	0.1	0.2	0.4	0.0
Heart disease (siblings)	0.1	0.1	0.1	0.3	-0.3
Pack years of smoking	0.1	0.1	0.2	0.5	0.2
Bipolar Disorder (2018)	0.0	0.1	0.1	0.2	0.3
Bipolar Disorder or Schizophrenia	0.0	0.1	0.1	-0.2	0.3
Schizophrenia (2018)	0.0	0.1	0.1	-0.4	0.1
Bipolar Disorder (2011)	0.0	0.0	0.1	-0.3	-0.0
HbA1C	0.0	0.0	0.0	0.2	-0.1
Tanning	0.0	0.5	0.8	0.9	0.4
Number of treatments/medications taken	0.0	0.1	0.1	0.3	-0.1
Ever used hormone-replacement therapy (HRT)	0.0	0.1	0.1	0.1	0.3
Tinnitus: Yes, but not now, but have in the past	0.0	0.1	0.1	-0.3	0.2
Medication: Levothyroxine sodium	0.0	0.1	0.1	0.2	0.3
Number of incorrect matches in round	0.0	0.0	0.0	0.0	0.1
Worrier / anxious feelings	0.0	0.0	0.0	-0.1	-0.2
Falls in the last year	0.0	0.0	0.0	-0.1	0.0
Standing height	0.0	0.5	1.0	0.1	-1.0
Medication for cholesterol, blood pressure or diabetes	0.0	0.1	0.1	-0.3	0.3
Eye problems/disorders: None of the above	0.0	0.0	0.0	0.2	0.1
Neck or shoulder pain in last month	0.0	0.0	0.0	0.2	-0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.0	0.0	0.0	-0.0	-0.2
Forced expiratory volume in 1-second (FEV1), predicted	0.0	0.1	0.2	-0.0	-0.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.0	0.0	0.1	-0.3	-0.1
Osteoporosis (self-reported)	0.0	0.1	0.1	-0.3	-0.0
Risk taking	0.0	0.0	0.0	0.2	0.2
Ever had prostate specific antigen (PSA) test	0.0	0.0	0.0	-0.2	-0.1
Fractured/broken bones in last 5 years	0.0	0.0	0.0	0.1	0.1
Ever depressed for a whole week	0.0	0.0	0.1	-0.1	0.2

Hub : Genes

ADPGK-AS1

Models

Trait associations