Best TWAS P=3.29e-09 · Best GWAS P=9.9e-12 conditioned to 0.000707
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Artery Tibial | SCAND2P | 0.12 | 0.05 | enet | 16 | 0.08 | 8.7e-07 | -2.810 | -5.2 | 2.0e-07 | 0.38 | 0.34 | 0.44 | FALSE |
2 | GTEx | Brain Cortex | GOLGA6L4 | 0.42 | 0.21 | lasso | 7 | 0.28 | 2.8e-08 | -5.308 | -5.5 | 2.9e-08 | 0.65 | 0.20 | 0.71 | FALSE |
3 | GTEx | Breast Mammary Tissue (Male) | GOLGA6L4 | 0.23 | 0.07 | lasso | 2 | 0.12 | 8.3e-04 | -5.308 | -5.2 | 1.9e-07 | 0.57 | 0.07 | 0.29 | FALSE |
4 | GTEx | Colon Transverse | AC103965.1 | 0.15 | 0.07 | enet | 33 | 0.06 | 7.1e-04 | -5.252 | -5.4 | 6.7e-08 | 0.50 | 0.12 | 0.42 | FALSE |
5 | GTEx | Colon Transverse | CSPG4P11 | 0.10 | 0.10 | lasso | 4 | 0.08 | 1.2e-04 | -5.252 | -5.2 | 2.3e-07 | 0.40 | 0.25 | 0.04 | FALSE |
6 | GTEx | Esophagus Muscularis | UBE2Q2P1 | 0.34 | 0.03 | lasso | 7 | 0.15 | 1.9e-09 | 2.794 | 5.9 | 3.3e-09 | -0.42 | 0.21 | 0.55 | TRUE |
7 | GTEx | Prostate | RP11-182J1.16 | 0.24 | 0.06 | enet | 27 | 0.08 | 6.2e-03 | -0.098 | -5.2 | 2.6e-07 | 0.48 | 0.07 | 0.26 | FALSE |
8 | GTEx | Prostate | CSPG4P11 | 0.34 | 0.07 | enet | 13 | 0.18 | 2.3e-05 | -1.804 | -5.2 | 2.3e-07 | 0.42 | 0.08 | 0.61 | FALSE |
9 | GTEx | Skin Sun Exposed Lower leg | AC103965.1 | 0.33 | 0.17 | enet | 24 | 0.23 | 4.8e-19 | 3.159 | -5.2 | 1.9e-07 | 0.50 | 1.00 | 0.00 | TRUE |
10 | GTEx | Spleen | GOLGA6L4 | 0.55 | 0.20 | enet | 19 | 0.40 | 2.6e-11 | -5.277 | -5.5 | 5.0e-08 | 0.54 | 0.86 | 0.05 | FALSE |
11 | GTEx | Whole Blood | GOLGA6L4 | 0.12 | 0.08 | enet | 16 | 0.11 | 2.1e-10 | -4.058 | -5.2 | 2.2e-07 | 0.58 | 0.86 | 0.14 | FALSE |