[Hub]/) : Traits : Leg fat mass (left) :

chr15:84,151,637-85,883,064

Best TWAS P=3.29e-09 · Best GWAS P=9.9e-12 conditioned to 0.000707

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Tibial SCAND2P 0.12 0.05 enet 16 0.08 8.7e-07 -2.810 -5.2 2.0e-07 0.38 0.34 0.44 FALSE
2 GTEx Brain Cortex GOLGA6L4 0.42 0.21 lasso 7 0.28 2.8e-08 -5.308 -5.5 2.9e-08 0.65 0.20 0.71 FALSE
3 GTEx Breast Mammary Tissue (Male) GOLGA6L4 0.23 0.07 lasso 2 0.12 8.3e-04 -5.308 -5.2 1.9e-07 0.57 0.07 0.29 FALSE
4 GTEx Colon Transverse AC103965.1 0.15 0.07 enet 33 0.06 7.1e-04 -5.252 -5.4 6.7e-08 0.50 0.12 0.42 FALSE
5 GTEx Colon Transverse CSPG4P11 0.10 0.10 lasso 4 0.08 1.2e-04 -5.252 -5.2 2.3e-07 0.40 0.25 0.04 FALSE
6 GTEx Esophagus Muscularis UBE2Q2P1 0.34 0.03 lasso 7 0.15 1.9e-09 2.794 5.9 3.3e-09 -0.42 0.21 0.55 TRUE
7 GTEx Prostate RP11-182J1.16 0.24 0.06 enet 27 0.08 6.2e-03 -0.098 -5.2 2.6e-07 0.48 0.07 0.26 FALSE
8 GTEx Prostate CSPG4P11 0.34 0.07 enet 13 0.18 2.3e-05 -1.804 -5.2 2.3e-07 0.42 0.08 0.61 FALSE
9 GTEx Skin Sun Exposed Lower leg AC103965.1 0.33 0.17 enet 24 0.23 4.8e-19 3.159 -5.2 1.9e-07 0.50 1.00 0.00 TRUE
10 GTEx Spleen GOLGA6L4 0.55 0.20 enet 19 0.40 2.6e-11 -5.277 -5.5 5.0e-08 0.54 0.86 0.05 FALSE
11 GTEx Whole Blood GOLGA6L4 0.12 0.08 enet 16 0.11 2.1e-10 -4.058 -5.2 2.2e-07 0.58 0.86 0.14 FALSE