[Hub]/) : Traits : Leg fat mass (left) : ← →

chr16:3,301,360-5,706,977

Best TWAS P=1.5e-20 · Best GWAS P=1.35e-25 conditioned to 3.79e-07

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
12	ROSMAP	Brain Pre-frontal Cortex	RP11-462G12.1	0.11	0.07	enet	18	0.06	1.1e-08	-10.1	-9.3	1.5e-20	0.86	0.00	1.00	TRUE
6	GTEx	Esophagus Muscularis	UBN1	0.18	0.19	lasso	4	0.19	9.1e-12	6.3	-6.1	8.1e-10	-0.04	0.07	0.93	TRUE
11	GTEx	Thyroid	RP11-95P2.1	0.15	0.10	lasso	5	0.10	3.9e-08	5.0	-5.4	6.5e-08	0.03	0.94	0.00	TRUE
7	GTEx	Nerve Tibial	UBN1	0.14	0.12	lasso	4	0.11	5.6e-08	6.2	-6.1	8.1e-10	-0.04	0.09	0.91	FALSE
5	GTEx	Esophagus Mucosa	UBN1	0.12	0.06	lasso	3	0.08	5.1e-06	5.8	-5.9	3.9e-09	-0.05	0.10	0.90	FALSE
10	GTEx	Skin Sun Exposed Lower leg	UBN1	0.16	0.15	lasso	5	0.17	9.5e-14	6.3	-5.7	1.3e-08	-0.05	0.08	0.92	FALSE
2	GTEx	Artery Aorta	UBN1	0.18	0.15	lasso	4	0.14	6.8e-08	6.3	-5.6	2.0e-08	-0.04	0.06	0.94	FALSE
9	GTEx	Skin Sun Exposed Lower leg	PPL	0.10	0.04	lasso	6	0.02	5.7e-03	5.8	5.6	2.7e-08	0.05	0.08	0.72	FALSE
13	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	ROGDI	0.03	0.04	lasso	3	0.03	1.6e-04	5.4	-5.4	8.5e-08	0.01	0.02	0.96	FALSE
4	GTEx	Cells Transformed fibroblasts	RP11-95P2.1	0.13	0.11	lasso	3	0.12	2.0e-09	4.9	-5.3	1.2e-07	0.05	1.00	0.00	FALSE
8	GTEx	Skin Not Sun Exposed Suprapubic	UBN1	0.22	0.16	lasso	4	0.14	2.5e-08	5.7	-5.3	1.4e-07	-0.04	0.11	0.89	FALSE
1	GTEx	Adipose Subcutaneous	RP11-95P2.1	0.12	0.01	lasso	3	0.02	1.0e-02	5.1	-5.2	2.6e-07	0.00	0.05	0.05	FALSE
3	GTEx	Artery Tibial	UBN1	0.20	0.06	lasso	7	0.07	4.8e-06	5.4	-5.1	2.8e-07	-0.02	0.16	0.84	FALSE