[Hub]/) : Traits : Leg fat mass (left) : ← →

chr16:3,301,360-5,706,977

Best TWAS P=1.5e-20 · Best GWAS P=1.35e-25 conditioned to 3.79e-07

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous RP11-95P2.1 0.12 0.01 lasso 3 0.02 1.0e-02 5.1 -5.2 2.6e-07 0.00 0.05 0.05 FALSE
2 GTEx Artery Aorta UBN1 0.18 0.15 lasso 4 0.14 6.8e-08 6.3 -5.6 2.0e-08 -0.04 0.06 0.94 FALSE
3 GTEx Artery Tibial UBN1 0.20 0.06 lasso 7 0.07 4.8e-06 5.4 -5.1 2.8e-07 -0.02 0.16 0.84 FALSE
4 GTEx Cells Transformed fibroblasts RP11-95P2.1 0.13 0.11 lasso 3 0.12 2.0e-09 4.9 -5.3 1.2e-07 0.05 1.00 0.00 FALSE
5 GTEx Esophagus Mucosa UBN1 0.12 0.06 lasso 3 0.08 5.1e-06 5.8 -5.9 3.9e-09 -0.05 0.10 0.90 FALSE
6 GTEx Esophagus Muscularis UBN1 0.18 0.19 lasso 4 0.19 9.1e-12 6.3 -6.1 8.1e-10 -0.04 0.07 0.93 TRUE
7 GTEx Nerve Tibial UBN1 0.14 0.12 lasso 4 0.11 5.6e-08 6.2 -6.1 8.1e-10 -0.04 0.09 0.91 FALSE
8 GTEx Skin Not Sun Exposed Suprapubic UBN1 0.22 0.16 lasso 4 0.14 2.5e-08 5.7 -5.3 1.4e-07 -0.04 0.11 0.89 FALSE
9 GTEx Skin Sun Exposed Lower leg PPL 0.10 0.04 lasso 6 0.02 5.7e-03 5.8 5.6 2.7e-08 0.05 0.08 0.72 FALSE
10 GTEx Skin Sun Exposed Lower leg UBN1 0.16 0.15 lasso 5 0.17 9.5e-14 6.3 -5.7 1.3e-08 -0.05 0.08 0.92 FALSE
11 GTEx Thyroid RP11-95P2.1 0.15 0.10 lasso 5 0.10 3.9e-08 5.0 -5.4 6.5e-08 0.03 0.94 0.00 TRUE
12 ROSMAP Brain Pre-frontal Cortex RP11-462G12.1 0.11 0.07 enet 18 0.06 1.1e-08 -10.1 -9.3 1.5e-20 0.86 0.00 1.00 TRUE
13 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma ROGDI 0.03 0.04 lasso 3 0.03 1.6e-04 5.4 -5.4 8.5e-08 0.01 0.02 0.96 FALSE