Hub : Genes

ROGDI

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Brain Caudate basal ganglia 0.3220 0.0920 9.1e-06 0.331 NA 0.296 NA 0.299 2.8e-10 NA 3.5e-09 NA 2.8e-09
2 GTEx Brain Frontal Cortex BA9 0.1890 0.0821 1.6e-03 0.030 NA 0.048 NA 0.003 5.4e-02 NA 2.0e-02 NA 2.7e-01
3 GTEx Brain Putamen basal ganglia 0.4120 0.1030 9.0e-07 0.384 NA 0.271 NA 0.299 4.2e-10 NA 3.7e-07 NA 7.9e-08
4 GTEx Cells Transformed fibroblasts 0.2300 0.0480 1.6e-09 0.241 NA 0.218 NA 0.232 4.6e-18 NA 2.8e-16 NA 2.4e-17
5 GTEx Lung 0.1951 0.0561 2.5e-04 0.102 NA 0.042 NA 0.063 3.2e-08 NA 3.8e-04 NA 1.4e-05
6 GTEx Testis 0.1690 0.0680 6.7e-04 0.087 NA 0.105 NA 0.092 1.1e-04 NA 2.1e-05 NA 7.1e-05
7 GTEx Whole Blood 0.1390 0.0470 2.9e-05 0.175 NA 0.179 NA 0.174 6.3e-16 NA 2.8e-16 NA 7.6e-16
8 METSIM Adipose 0.2081 0.0364 0.0e+00 0.182 0.156 0.205 0.188 0.207 1.9e-26 1.3e-22 5.5e-30 2.0e-27 2.4e-30
9 ROSMAP Brain Pre-frontal Cortex 0.2587 0.0427 0.0e+00 0.299 0.257 0.300 0.298 0.293 7.0e-39 7.5e-33 5.1e-39 8.3e-39 4.3e-38
10 YFS Blood 0.2398 0.0324 0.0e+00 0.185 0.160 0.198 0.201 0.200 2.7e-58 6.9e-50 8.2e-63 7.4e-64 2.0e-63
11 TCGA Breast Invasive Carcinoma 0.0211 0.0106 4.6e-05 0.012 0.019 0.012 NA 0.012 1.3e-03 7.7e-05 1.2e-03 NA 1.1e-03
12 TCGA Kidney Renal Clear Cell Carcinoma 0.0328 0.0175 9.0e-04 0.039 0.020 0.030 NA 0.031 2.7e-05 2.2e-03 2.2e-04 NA 1.6e-04
13 TCGA Brain Lower Grade Glioma 0.0487 0.0343 5.9e-03 0.018 0.017 0.024 NA 0.025 3.3e-03 4.6e-03 8.4e-04 NA 6.0e-04
14 TCGA Prostate Adenocarcinoma 0.1309 0.0485 9.1e-15 0.147 0.143 0.145 NA 0.135 3.8e-15 9.0e-15 5.6e-15 NA 6.2e-14

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
Bipolar Disorder (2018) 0.1 0.2 0.8 0.8 0.9 0.5 -0.3 0.1 0.4 -0.4 -0.2 -0.1 -0.1 -0.1 0.1 0.7 -0.4
Bipolar Disorder or Schizophrenia 0.5 1.2 3.3 0.4 0.0 0.9 -1.5 -1.4 -0.3 -1.3 -1.4 1.0 -1.8 0.1 -0.1 1.8 -0.6
Depressed Affect (Nagel 2018) 0.9 2.0 7.6 1.6 0.4 2.0 -1.2 -0.9 0.5 -0.8 0.1 2.6 -0.8 2.8 0.8 1.0 1.0
Depression (Nagel 2018) 0.4 0.6 2.9 0.7 -1.3 0.8 -0.6 -0.2 -0.1 -0.4 0.2 1.7 -0.4 1.4 -0.1 0.2 0.7
Intelligence (Savage-Jansen 2018) 2.8 8.5 16.6 -2.6 -2.6 -3.5 2.6 1.9 -2.6 2.2 2.4 -4.1 1.4 -3.3 -3.3 -3.4 -3.6
Neuroticism (Nagel 2018) 1.1 2.6 7.4 2.0 1.5 2.3 -0.9 -0.6 1.2 -0.7 0.0 2.7 -0.1 2.7 1.5 1.2 1.6
Schizophrenia (2018) 0.7 1.6 4.8 -0.2 -0.7 0.7 -1.7 -1.9 -0.4 -1.3 -1.6 1.3 -2.2 0.1 -0.2 1.8 -0.5
Schizophrenia vs Biploar Disorder 1.2 1.5 5.2 -1.7 -1.6 -1.3 0.4 -0.6 -2.3 0.6 0.2 -1.7 -0.3 -1.3 -1.2 -1.1 -0.8
Worry (Nagel 2018) 0.2 0.4 1.4 0.3 0.7 0.5 0.2 0.4 0.1 0.5 0.4 0.6 0.9 1.2 0.7 -0.1 0.9
Alzheimer’s Disease (in mother) 0.7 0.8 1.6 1.2 0.9 1.3 -1.0 -1.1 1.0 -0.8 -0.5 0.8 -0.6 1.0 0.7 0.0 0.9
Alzheimer’s Disease (in father) 0.3 0.3 1.3 0.8 0.0 0.3 -0.5 -0.4 -0.6 -0.5 -1.2 -0.3 -0.3 0.1 0.6 -0.4 -0.2
Alzheimer’s Disease (including proxy) 1.1 1.6 3.9 2.0 0.8 1.9 -1.1 -0.8 1.1 -1.1 -0.8 1.8 -0.5 1.6 1.5 0.4 1.3
Crohns Disease (2017) 1.6 3.4 10.1 -0.8 -2.0 -1.5 -0.6 -1.3 -2.1 -0.7 -1.0 -1.7 -1.7 -2.1 -3.2 -2.0 -3.0
Irritable Bowel Disease (IBD) 1.7 4.1 10.8 -1.6 -2.5 -2.0 1.5 0.9 -1.8 1.5 0.8 -2.1 0.6 -2.4 -3.3 -2.8 -2.6
Ulcerative Colitis (UC) 1.4 2.7 4.7 -1.6 -1.5 -1.6 2.1 1.9 -0.4 2.1 1.7 -1.4 1.9 -1.2 -1.4 -2.2 -0.9
Major Depression (MDD) 0.6 0.7 2.7 -0.4 -1.0 -0.6 -0.1 -0.2 -1.6 0.0 -0.5 -0.2 -0.5 -0.7 -1.3 -1.0 -1.4
Reaction Time 1.0 1.9 5.2 1.4 -0.7 1.6 -1.2 -1.2 1.3 -0.9 -1.3 1.3 -0.9 1.7 1.4 2.3 1.5
Verbal and Numeric Reasoning (VNR) 3.1 7.4 15.2 -2.7 -3.2 -3.5 1.7 1.0 -2.9 1.3 2.0 -3.9 0.3 -3.0 -3.1 -3.3 -3.2
Breast Cancer 0.6 1.6 2.9 -1.5 0.7 -1.3 1.7 1.0 -0.4 1.6 1.2 -1.3 1.4 -1.0 -1.2 -1.7 -0.3
Ovarian Cancer 0.2 0.2 0.7 0.1 0.3 0.2 0.5 0.8 -0.1 0.7 0.8 0.2 0.8 0.3 0.3 0.2 0.5
Prostate Cancer 4.7 6.6 13.5 1.8 2.7 2.7 -2.2 -2.5 3.7 -2.1 -1.9 3.1 -1.4 2.3 3.6 2.5 2.4
Age at First Birth 0.8 1.2 2.2 1.3 0.8 1.3 -1.2 -1.2 0.6 -1.1 -1.0 1.2 -0.8 1.2 1.2 1.5 0.7
Bipolar Disorder (2011) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
Body Mass Index (BMI) (2010) 3.5 4.8 12.0 -2.5 -3.5 -2.7 0.9 0.1 -2.4 1.0 -0.1 -2.5 -0.3 -2.8 -2.8 -2.3 -2.7
Coronary Artery Disease (CAD) 0.4 0.5 2.2 0.0 1.0 0.1 -0.8 -0.9 0.4 -0.9 -1.5 0.8 -0.8 0.0 0.1 0.1 0.7
Crohns Disease (2012) 0.9 1.5 5.5 0.1 -1.4 -0.2 -1.5 -1.2 -1.6 -1.4 -1.6 0.1 -2.3 -0.5 -1.3 0.0 -0.7
Mean Putamen Volume 0.1 0.1 0.5 -0.2 0.6 -0.5 0.0 -0.3 0.2 -0.4 -0.5 -0.3 -0.1 -0.7 -0.1 -0.4 -0.0
Fasting Glucose 0.6 0.8 2.1 -1.5 0.4 -1.3 0.1 -0.4 1.2 -0.0 0.3 -1.2 -0.1 -1.1 0.0 -1.4 -0.3
HbA1C 0.2 0.3 1.0 -0.3 1.0 -0.5 0.1 0.2 -0.6 -0.0 -0.1 -0.3 0.2 -0.6 -0.3 0.4 -1.0
HDL Cholesterol 3.5 5.8 10.5 2.5 3.2 2.6 -2.2 -2.0 2.2 -1.8 -2.1 3.0 -0.8 2.7 2.9 2.1 2.6
LDL Cholesterol 2.4 3.9 8.5 -2.0 -1.8 -2.3 1.0 0.7 -2.6 0.6 0.3 -2.5 -0.3 -2.9 -2.8 -1.4 -2.8
Lupus 0.9 1.4 5.4 -0.3 0.0 -0.7 2.0 1.9 0.6 1.7 1.2 -0.0 2.3 0.1 -0.1 -0.8 0.5
Neuroticism (2016) 0.3 0.5 1.3 0.7 0.9 0.8 -0.1 -0.2 1.1 -0.2 -0.7 1.1 0.3 0.4 0.6 0.4 1.1
Primary Biliary Cirrhosis 0.1 0.1 1.1 0.1 1.1 0.1 -0.2 -0.5 0.0 0.1 0.1 0.0 0.2 0.5 0.2 0.2 -0.0
Rheumatoid Arthritis 1.2 1.7 3.4 -1.1 -1.5 -1.1 1.4 1.8 -1.4 1.6 1.4 -0.6 1.8 -0.3 -0.2 -1.7 0.8
Schizophrenia (2014) 0.7 1.6 4.9 -0.2 -1.1 0.7 -1.4 -1.7 -1.6 -1.0 -1.3 0.6 -2.2 -0.4 -0.9 1.4 -1.2
Triglycerides 4.9 8.0 10.3 -3.1 -2.9 -3.2 3.1 2.7 -2.4 3.0 2.9 -3.1 1.9 -2.8 -3.1 -2.7 -2.4
Type 2 Diabetes (T2D) (2012) 0.1 0.1 0.6 0.4 -0.8 0.2 -0.3 -0.2 0.1 -0.1 -0.3 -0.2 -0.3 -0.4 -0.4 -0.4 -0.5
Ulcerative Colitis 0.6 0.9 3.4 -0.4 -0.3 -0.6 1.2 1.9 -0.9 1.3 1.4 -0.7 1.3 -0.4 -0.6 -0.5 0.0
Blood Eosinophil Count 1.2 8.9 15.5 2.0 2.5 2.7 -3.4 -3.6 3.9 -3.0 -3.3 3.6 -3.0 2.0 2.8 3.2 2.0
Blood Platelet Count 1.4 15.8 31.6 3.2 1.5 4.0 -4.1 -5.6 5.5 -4.0 -4.5 4.2 -3.3 3.2 3.9 4.0 2.8
Blood Red Count 0.1 0.7 5.6 0.2 -0.9 -0.4 -0.1 0.0 -2.4 0.6 -0.3 -0.5 0.0 -0.5 -0.9 -0.5 -1.0
Blood White Count 1.1 8.0 14.6 2.4 2.0 2.6 -3.5 -3.6 3.7 -3.3 -3.8 3.1 -3.3 1.4 1.8 2.0 0.9
Heel T-Score 0.5 3.8 14.0 -0.5 0.5 -0.2 3.0 3.0 -0.3 3.7 3.1 -0.0 2.5 0.3 -1.4 -1.3 -1.1
BMI 3.4 19.8 39.4 -4.3 -3.9 -5.2 3.9 3.5 -4.7 3.6 2.8 -4.7 2.0 -5.0 -6.3 -5.7 -4.7
Height 3.0 58.5 90.2 -7.4 -7.1 -8.8 8.4 7.8 -8.0 8.5 7.4 -9.5 6.7 -5.8 -6.9 -8.0 -5.6
Waist Hip Ratio (WHR) 0.6 2.5 8.3 -2.9 -0.2 -1.8 1.5 1.0 0.6 2.2 1.2 -1.5 0.5 -1.3 -1.2 -2.5 -1.3
Systolic Blood Pressure 3.3 16.7 38.6 4.7 2.9 5.4 -2.9 -2.0 5.6 -2.9 -1.5 6.2 -1.1 5.2 4.8 4.2 3.6
Smoking Status 0.3 0.8 3.2 0.3 1.8 0.3 -0.9 -1.3 1.2 -1.1 -1.0 0.3 -1.1 -0.7 -0.1 -0.2 -0.4
Allergy or Eczema 0.3 0.9 3.5 0.4 -0.0 0.7 -0.0 -0.3 1.3 -0.0 -0.5 1.2 0.6 0.6 1.7 0.8 1.9
Cardiovascular Disease 2.2 7.2 16.8 3.2 1.9 3.8 -0.8 0.2 3.9 -0.8 0.2 4.1 0.4 3.9 3.1 3.0 2.5
Hypothyroidism (self reported) 0.4 0.9 2.7 1.1 0.6 1.1 -0.3 -0.2 1.7 -0.3 -0.8 1.1 0.1 0.4 0.7 1.4 1.4
Respiratory disease 0.1 0.3 0.8 -0.1 0.7 0.1 -0.4 -0.5 0.5 -0.5 -0.3 -0.8 -0.3 -0.9 0.9 0.0 -0.3
Type 2 Diabetes (T2D) (2018) 0.1 0.1 0.3 0.3 0.1 0.3 -0.2 0.3 -0.0 -0.3 -0.1 0.3 -0.5 -0.3 -0.4 0.5 -0.3
Lung FEV1/FVC ratio 0.3 1.4 4.4 -0.0 -0.4 -0.7 -1.6 -1.4 -1.6 -2.1 -1.6 -0.1 -1.9 -0.9 -1.0 -0.1 -0.3
Lung FVC 0.5 2.5 6.6 -1.7 -2.6 -1.6 1.7 1.0 -0.6 2.2 0.9 -1.7 1.2 -1.0 -1.1 -1.3 -2.1
Neuroticism 1.1 2.6 8.9 1.9 0.3 2.4 -0.1 0.2 1.1 0.5 0.6 2.6 0.9 3.0 1.6 1.7 1.9
Chronotype (morning person) 0.3 0.6 1.6 0.8 0.7 0.4 0.3 1.2 1.3 0.0 0.8 0.4 0.7 1.0 1.0 0.5 0.8
Hair Pigment 0.1 2.5 19.2 1.1 4.4 0.8 -0.1 0.5 2.5 -0.7 0.2 1.3 0.6 1.0 1.1 -0.1 1.6
Tanning 0.1 0.7 1.8 -1.2 -1.2 -1.1 0.2 -0.5 -0.6 0.2 -0.1 -0.6 -0.4 -1.3 -0.9 -0.9 -1.3
Hand grip strength (left) 0.6 1.5 5.0 -1.1 -1.9 -1.1 0.4 0.5 -2.2 1.2 0.5 -1.8 0.1 -0.9 -0.9 -0.6 -1.7
Number of treatments/medications taken 0.6 1.1 3.3 0.8 0.6 0.8 0.2 0.5 1.8 0.1 0.7 0.9 1.2 1.2 1.8 0.1 1.8
Average weekly spirits intake 0.1 0.2 0.5 0.1 0.3 0.2 -0.5 -0.5 -0.7 -0.4 0.2 0.1 -0.7 0.5 -0.1 0.3 -0.3
Sensitivity / hurt feelings 0.2 0.4 1.0 -0.4 0.7 0.3 0.6 0.7 0.6 1.0 0.7 0.7 0.7 0.3 0.3 0.2 0.5
Frequency of depressed mood in last 2 weeks 0.5 0.7 2.8 0.7 -0.0 0.9 -0.7 -0.1 0.6 -0.6 0.0 1.7 -0.4 1.5 0.3 0.6 0.9
Hearing difficulty/problems: Yes 0.2 0.3 1.0 0.7 1.0 0.8 -0.3 -0.6 0.6 -0.3 -0.6 0.9 -0.0 0.5 0.4 0.2 0.1
Relative age of first facial hair 1.8 3.7 7.7 2.2 2.8 2.1 -1.3 -1.0 2.8 -1.0 -1.0 2.3 -0.3 2.2 2.0 1.9 2.0
Other serious medical condition/disability diagnosed by doctor 0.2 0.3 0.9 -0.4 0.2 -0.7 -0.2 -0.3 0.0 -0.3 -0.8 -0.4 -0.4 -0.9 -0.5 -0.7 -0.4
Ever used hormone-replacement therapy (HRT) 0.3 0.4 1.1 -0.9 -0.8 -1.1 0.1 0.1 0.0 -0.6 -0.3 -0.4 0.1 -0.9 -0.1 -1.0 -0.3
Ever had hysterectomy (womb removed) 1.2 1.3 3.2 -1.4 -0.5 -1.8 1.1 0.4 -0.9 1.3 1.1 -1.3 0.9 -1.4 -1.0 -1.3 -1.0
Systolic blood pressure, automated reading 1.0 3.0 7.4 1.8 1.1 2.2 -1.4 -0.8 2.3 -1.6 -0.6 2.7 -0.4 2.1 2.3 1.5 1.6
Eye problems/disorders: Diabetes related eye disease 0.1 0.1 0.4 -0.6 0.2 -0.3 0.0 0.4 0.2 -0.0 0.4 -0.4 -0.0 0.1 0.0 -0.4 -0.2
Angina 0.8 1.0 3.8 -0.9 -0.2 -1.0 0.8 0.4 0.1 0.4 1.2 -1.8 0.6 -0.8 -0.3 -1.9 -1.2
Medication for hormone replacement therapy 0.7 0.8 2.3 1.1 0.5 0.8 -1.3 -0.5 0.4 -1.5 -0.8 0.9 -1.2 0.3 0.4 0.9 -0.2
Vitamin and mineral supplements 0.4 0.5 1.1 -1.0 0.3 -1.0 0.7 0.8 -0.3 1.0 0.2 -0.7 1.0 -0.1 -0.3 -1.0 -0.0
Supplements: Zinc 0.4 0.4 1.0 -0.5 0.1 -0.3 -0.8 -1.0 0.6 -1.0 -0.9 -0.4 -0.9 -0.7 0.2 0.2 -0.1
Medication: Co-codamol 1.2 1.4 2.9 -0.8 -1.3 -1.2 1.7 1.4 -0.7 1.6 1.2 -1.3 1.7 -0.5 -0.9 -0.9 -0.2
Medication: Metformin 1.3 1.9 3.2 -1.5 -1.7 -1.5 1.1 1.6 -1.8 0.8 1.3 -1.2 0.4 -1.3 -1.8 -1.2 -1.2
Diabetes (father) 0.2 0.3 0.9 -0.3 0.5 -0.3 0.4 0.8 -0.9 0.5 0.7 -0.9 0.6 -0.2 -0.4 0.1 -0.1
Diabetes (mother) 0.4 0.6 1.8 1.0 1.1 1.1 -0.2 -0.1 0.8 0.2 -0.3 1.3 0.2 1.0 0.1 0.5 0.7
Severe depression (siblings) 0.4 0.5 2.7 -0.0 0.1 0.1 0.4 1.2 -0.8 0.3 0.4 0.2 -0.3 -0.4 -1.6 -0.7 -1.0
Pack years adult smoking proportion 0.9 1.4 5.5 -0.9 -1.7 -1.1 1.3 0.9 0.1 1.7 0.9 -1.0 1.4 -0.1 -0.5 -2.4 -0.5
Impedance of leg (right) 0.9 4.1 8.8 2.1 0.8 2.3 -2.0 -2.0 2.0 -1.6 -2.1 2.2 -1.2 1.9 3.0 2.6 1.7
Leg fat-free mass (left) 4.3 22.8 34.9 -4.7 -4.4 -5.6 4.5 4.3 -5.4 4.4 4.2 -5.7 2.9 -4.2 -5.7 -5.9 -4.1
Trunk fat percentage 3.6 14.2 25.8 -3.9 -4.9 -4.3 2.6 2.3 -5.1 2.5 1.9 -4.5 0.8 -3.7 -4.7 -4.3 -4.3
Hand grip strength (right) 0.7 1.8 4.3 -1.0 -1.5 -1.2 1.0 1.1 -1.9 1.6 1.3 -2.1 0.8 -0.6 -1.0 -1.6 -1.2
Townsend deprivation index at recruitment 0.1 0.1 0.4 -0.1 0.4 0.0 -0.2 -0.4 0.6 0.0 0.1 0.0 -0.2 0.3 0.0 0.4 0.2
Current tobacco smoking 1.0 1.6 4.3 -1.1 -0.8 -1.2 0.5 -0.1 -1.2 0.2 0.3 -1.8 -0.5 -1.8 -1.8 -1.7 -2.1
Average weekly fortified wine intake 1.2 1.4 2.1 1.0 -0.9 0.9 -1.3 -1.4 1.0 -1.4 -1.4 1.2 -1.2 0.9 1.3 1.2 0.9
Maternal smoking around birth 2.6 3.8 11.7 1.7 3.4 1.8 -1.9 -2.0 2.5 -2.0 -2.2 1.4 -1.4 0.8 1.8 1.0 1.9
Fed-up feelings 2.0 3.6 8.4 2.3 0.5 2.4 -2.1 -1.6 1.5 -1.6 -1.4 2.9 -1.4 2.5 1.5 1.5 2.0
Frequency of unenthusiasm / disinterest in last 2 weeks 2.3 3.0 6.1 2.0 -0.7 2.4 -1.9 -1.3 0.8 -1.6 -1.2 2.5 -1.6 2.5 1.0 2.1 1.4
Relative age voice broke 1.8 2.7 5.5 2.0 2.0 1.8 -1.5 -1.0 1.8 -1.3 -0.9 2.3 -0.9 1.9 1.5 1.9 1.1
Taking other prescription medications 0.1 0.2 0.5 0.1 0.7 -0.0 0.2 0.6 0.3 0.3 0.2 0.0 0.6 0.5 0.7 -0.4 0.7
Age when periods started (menarche) 0.5 1.2 3.6 1.1 0.2 0.8 -1.3 -1.9 1.4 -1.6 -1.6 0.2 -1.1 -0.1 1.0 0.1 0.4
Bilateral oophorectomy (both ovaries removed) 0.3 0.3 0.9 -0.5 -0.4 -0.7 -0.7 -0.5 -0.9 -0.4 -0.7 -0.4 -0.9 -0.7 -0.2 -0.3 -0.4
Heel bone mineral density (BMD) T-score, automated (left) 0.3 0.8 2.0 -0.3 0.2 -0.3 1.2 1.2 -0.9 1.4 1.3 -0.5 0.7 -0.1 -0.9 -0.8 -1.0
Tinnitus: Yes, but not now, but have in the past 0.1 0.2 0.5 0.5 0.2 0.5 -0.4 -0.4 0.1 -0.3 -0.4 -0.2 -0.1 0.4 0.7 0.0 0.4
Qualifications: CSEs or equivalent 0.6 0.8 2.6 0.2 1.5 1.0 -0.5 0.2 1.0 -0.4 0.1 1.2 -0.4 0.6 0.8 0.9 1.6
Serious illness, injury or assault to yourself 0.1 0.1 0.5 0.1 0.7 0.1 0.2 0.1 0.1 0.2 0.2 -0.5 0.5 -0.1 0.0 -0.5 -0.4
High blood pressure 1.6 4.6 10.9 2.4 1.8 2.8 -0.0 0.9 3.3 -0.2 1.3 3.0 1.1 3.2 2.3 1.8 2.1
Hayfever, allergic rhinitis or eczema 0.4 0.8 2.6 0.3 0.2 0.5 -0.5 -0.7 0.9 -0.5 -0.9 1.1 -0.0 0.6 1.6 1.1 1.6
Multivitamins +/- minerals 0.3 0.4 1.4 0.6 -0.9 0.5 0.9 0.3 -0.3 0.7 1.2 -0.2 1.0 0.1 -0.0 -0.1 0.1
Stomach or abdominal pain in last month 0.5 0.6 3.5 0.4 1.9 0.6 0.7 0.8 -0.5 0.4 1.5 -0.0 1.0 0.4 0.2 0.4 0.1
Supplements: Glucosamine 0.9 1.1 4.4 -0.8 -0.3 -0.8 0.5 0.5 -1.1 -0.2 0.5 -0.9 -0.4 -2.1 -1.8 -0.9 -1.8
Diverticular disease/diverticulitis (self-reported) 0.6 0.7 2.8 -0.6 -0.7 -1.1 0.4 -0.1 -1.0 0.3 0.1 -1.5 0.6 -0.7 -0.5 -1.7 -0.6
Medication: Atenolol 1.0 1.3 3.0 0.6 -0.8 0.9 -1.5 -1.2 1.7 -1.7 -0.6 0.3 -1.2 1.0 1.5 0.7 0.7
Medication: Levothyroxine sodium 0.1 0.2 0.7 -0.5 -0.0 -0.4 0.6 0.4 0.5 0.5 -0.1 -0.4 0.7 -0.8 -0.2 -0.3 0.1
Sitting height 1.8 13.1 19.2 -2.8 -3.2 -4.0 4.0 3.9 -4.3 3.7 3.4 -4.4 3.2 -3.1 -3.5 -3.9 -2.8
Chronic bronchitis/emphysema (father) 1.9 2.2 5.6 -1.5 -1.2 -1.4 0.4 0.5 -1.9 0.1 0.5 -1.7 -0.6 -1.8 -2.4 -1.9 -2.4
High blood pressure (mother) 2.0 2.8 7.6 1.1 2.4 1.6 -1.2 -0.8 2.1 -0.9 -1.0 2.8 -0.6 1.7 1.4 1.8 2.2
Body mass index (BMI) 2.6 11.3 22.7 -3.5 -3.0 -4.0 2.7 2.6 -3.7 2.5 2.2 -3.6 1.3 -3.4 -4.8 -4.6 -3.4
Impedance of leg (left) 1.0 4.7 9.4 2.4 0.8 2.6 -2.0 -2.0 1.9 -1.8 -2.2 2.3 -1.2 2.1 3.0 3.1 1.8
Leg predicted mass (left) 4.2 22.1 34.2 -4.6 -4.3 -5.5 4.4 4.2 -5.4 4.3 4.1 -5.6 2.8 -4.1 -5.6 -5.8 -4.1
Trunk fat mass 4.9 21.0 35.3 -4.6 -5.5 -5.3 3.6 3.3 -5.9 3.4 3.0 -5.6 1.6 -4.3 -5.6 -5.3 -4.8
Waist circumference 5.4 19.8 33.4 -4.9 -3.9 -5.4 4.0 3.7 -4.4 4.1 3.3 -5.2 2.3 -4.2 -5.6 -5.8 -4.2
Number of incorrect matches in round 0.3 0.5 1.0 0.7 0.9 0.7 -0.9 -0.7 0.1 -1.0 -0.8 0.9 -0.9 0.7 0.3 0.4 0.0
Past tobacco smoking 0.3 0.5 2.4 0.5 -1.6 0.7 0.5 0.7 -0.7 0.6 0.7 0.3 0.0 0.8 -0.4 1.2 -0.1
Alcohol usually taken with meals 4.4 7.1 13.2 -3.1 -2.8 -3.2 2.0 2.0 -3.1 1.4 2.0 -3.6 0.8 -2.9 -3.1 -2.5 -3.4
Nervous feelings 1.3 2.4 6.2 1.4 1.7 1.7 -1.0 -0.1 1.8 -0.6 -0.5 1.7 0.2 2.2 2.4 1.2 2.5
Frequency of tenseness / restlessness in last 2 weeks 1.0 1.6 4.9 0.5 0.6 1.0 -0.8 -0.6 1.9 -0.7 -0.6 2.2 0.0 2.2 1.4 0.4 1.8
Hearing difficulty/problems with background noise 1.1 1.7 3.6 1.6 1.3 1.6 0.4 -0.0 1.9 0.5 -0.1 1.5 1.6 1.7 1.7 0.8 1.5
Hair/balding pattern: Pattern 2 0.8 1.0 2.1 -0.6 0.3 -1.1 0.6 1.0 -1.1 0.1 1.0 -1.4 0.1 -1.2 -1.2 -1.4 -1.3
Had menopause 0.1 0.2 0.5 -0.3 0.2 -0.2 0.4 0.6 0.7 -0.1 0.3 -0.4 0.7 -0.1 0.4 -0.4 0.3
Had other major operations 1.2 1.4 4.0 -1.4 -0.3 -1.7 0.3 0.1 -2.0 0.0 -0.2 -1.9 0.0 -1.8 -1.1 -1.3 -1.0
Forced vital capacity (FVC) 1.9 7.3 12.8 -2.4 -3.6 -2.8 3.0 2.5 -2.6 3.4 2.5 -3.3 2.7 -1.4 -1.8 -2.8 -2.0
Heel bone mineral density (BMD) T-score, automated (right) 0.6 1.4 2.6 1.0 1.5 1.0 1.1 1.4 0.6 1.4 1.4 1.0 1.3 1.6 0.5 0.5 1.1
Ever unenthusiastic/disinterested for a whole week 1.2 1.5 3.6 1.5 1.3 1.4 0.5 0.7 1.5 0.8 0.8 1.7 1.3 1.9 1.2 0.4 1.2
Qualifications: None of the above 1.4 2.9 6.8 2.2 1.5 2.0 -0.4 -0.3 2.6 -0.7 -0.4 1.9 0.9 2.4 2.5 1.0 2.3
Financial difficulties in last 2 years 0.8 1.0 2.7 0.8 -1.1 1.1 -0.9 -1.1 1.2 -0.6 -1.0 1.6 -0.9 0.9 0.6 0.5 1.2
Mouth/teeth dental problems 0.4 0.6 1.8 -0.6 -0.7 -0.5 0.9 0.7 -0.7 1.3 0.6 -0.6 0.6 -0.3 -0.4 1.2 -0.5
Heart attack 0.2 0.3 0.6 0.5 0.7 0.3 -0.5 -0.4 0.4 -0.8 -0.5 -0.5 -0.2 -0.2 0.7 -0.7 -0.2
Allergy 0.5 1.1 4.2 -0.4 -0.8 -0.7 1.0 1.1 -1.3 1.1 1.2 -0.9 0.4 -0.6 -2.0 -0.8 -1.4
Pain all over the body in last month 1.1 1.2 3.5 -1.9 -0.8 -1.8 0.0 -0.5 -0.7 -0.2 -0.2 -1.2 -0.4 -1.7 -0.8 -1.6 -0.4
Diabetes (self-reported) 0.1 0.1 0.6 0.2 0.0 0.1 0.1 0.6 0.2 0.1 0.4 -0.2 0.1 -0.3 -0.0 0.8 -0.0
Hayfever/allergic rhinitis (self-reported) 0.3 0.5 1.2 0.2 -0.3 0.2 -0.8 -0.6 0.9 -1.0 -0.7 0.3 -0.5 0.2 1.1 0.3 1.1
Medication: Ramipril 0.2 0.3 0.8 0.2 0.1 0.1 0.7 0.7 0.1 0.6 0.9 -0.2 0.9 0.3 -0.3 -0.1 -0.6
Medication: Simvastatin 0.2 0.3 0.8 0.9 0.3 0.8 -0.5 -0.4 0.6 -0.8 -0.6 0.5 -0.3 0.2 0.5 0.1 0.6
Fluid intelligence score 1.6 3.2 5.8 -1.6 -1.8 -2.4 1.2 0.9 -2.0 1.0 1.2 -2.2 0.2 -2.0 -2.1 -2.4 -2.4
Illnesses of siblings 0.8 1.2 2.4 -1.4 -1.6 -1.4 1.2 1.0 -1.1 1.2 1.0 -1.0 0.9 -0.4 -0.7 -1.2 -0.2
Neuroticism score 1.7 3.5 10.5 2.2 1.1 2.6 -0.8 -0.1 1.6 -0.3 0.1 3.0 0.2 3.2 2.0 1.8 2.4
Weight 5.6 27.3 41.2 -5.1 -5.1 -6.1 4.8 4.6 -6.0 4.7 4.1 -6.2 3.0 -4.7 -6.4 -6.4 -4.8
Impedance of arm (right) 0.6 2.6 6.3 1.1 -1.0 1.3 -2.0 -2.1 0.7 -1.6 -2.3 0.7 -1.9 0.8 2.2 2.5 0.5
Arm fat percentage (right) 2.4 9.6 18.0 -3.2 -3.9 -3.6 1.9 1.7 -4.0 1.9 1.3 -3.6 0.3 -3.3 -4.2 -3.6 -3.7
Trunk fat-free mass 3.2 18.5 29.2 -3.7 -3.1 -4.8 4.5 4.4 -4.7 4.4 4.3 -5.0 3.4 -3.3 -5.0 -5.4 -3.4
Hip circumference 4.1 17.5 26.3 -3.9 -4.3 -5.0 3.8 3.8 -5.0 3.7 3.0 -5.0 2.5 -3.6 -5.1 -5.1 -3.8
Time employed in main current job 2.5 2.9 5.1 -2.3 -0.4 -2.0 1.9 1.7 -1.4 2.0 1.5 -1.9 1.7 -1.6 -1.2 -2.0 -1.2
Alcohol intake versus 10 years previously 0.5 0.8 2.0 1.0 -0.2 0.6 0.8 1.4 -0.1 1.1 1.2 0.3 1.4 1.1 0.6 0.5 0.5
Father’s age at death 0.6 0.8 3.2 0.0 -0.8 0.2 -1.3 -1.8 -0.1 -1.4 -1.3 0.8 -1.3 -0.0 0.6 0.2 -0.1
Worrier / anxious feelings 0.4 0.8 2.2 0.2 -0.1 0.5 1.1 1.4 -0.3 1.3 1.3 0.7 1.5 1.0 0.1 -0.3 0.6
Frequency of tiredness / lethargy in last 2 weeks 0.2 0.3 1.6 -0.2 -0.9 -0.0 0.2 0.6 0.6 0.2 -0.1 0.6 0.3 0.6 0.3 0.1 1.3
Falls in the last year 0.6 0.8 1.6 0.6 0.6 0.6 -1.1 -0.4 1.0 -1.0 -1.0 1.2 -0.8 1.3 1.0 -0.1 1.0
Hair/balding pattern: Pattern 3 0.6 0.9 2.1 0.6 -0.3 1.0 0.5 0.5 0.2 1.0 0.0 0.8 1.3 1.4 1.4 0.8 1.5
Number of live births 0.1 0.2 1.0 0.1 -0.6 0.2 0.1 -0.1 0.9 0.2 -1.0 0.1 0.0 -0.3 0.2 0.1 0.4
Forced expiratory volume in 1-second (FEV1) 1.4 4.9 12.4 -1.8 -3.5 -2.2 2.4 1.9 -2.4 2.9 1.9 -2.5 2.3 -0.9 -1.6 -1.9 -1.4
Pulse rate 1.5 2.5 5.5 1.3 1.5 1.3 -2.1 -1.9 1.4 -2.2 -2.4 2.0 -2.1 0.3 0.4 0.7 0.7
Happiness 2.5 3.0 8.0 2.1 1.2 2.0 -1.4 -1.1 1.9 -0.9 -1.7 2.8 -0.6 2.3 1.5 1.7 1.6
Noisy workplace 0.8 1.0 2.5 0.4 0.5 0.5 0.9 1.3 -0.3 0.6 1.5 0.3 1.5 1.2 1.3 -0.1 1.6
Qualifications: A levels/AS levels or equivalent 3.6 7.9 16.6 -3.8 -2.4 -4.1 2.2 1.6 -2.8 2.4 1.6 -3.6 1.3 -3.0 -2.7 -3.6 -2.6
Serious illness, injury or assault of a close relative in last 2 years 1.6 1.9 3.8 -1.0 -1.1 -1.2 -1.4 -1.2 -1.5 -1.4 -1.3 -1.1 -1.9 -1.5 -1.3 -1.3 -1.7
Mouth/teeth dental problems: Dentures 0.6 0.9 3.2 -0.6 -0.9 -0.5 1.1 1.0 -0.6 0.7 1.3 -0.9 0.8 -0.4 -1.1 -1.8 -0.9
Asthma 0.2 0.5 1.3 -0.0 0.7 0.0 -0.8 -0.8 0.5 -1.1 -0.7 -0.7 -0.9 -0.8 0.7 0.1 -0.1
Medication: Ibuprofen (e.g. Nurofen) 0.5 0.7 2.2 1.5 1.2 1.1 0.0 0.2 0.8 -0.1 0.2 0.4 0.4 0.8 0.8 0.9 1.0
Medication: Cholesterol lowering 0.1 0.2 1.4 -0.3 -1.2 0.0 0.2 0.6 -0.1 -0.1 0.4 -0.5 -0.1 -0.1 0.2 -0.0 -0.5
Depression (self-reported) 1.5 1.8 4.8 -0.8 -1.1 -0.8 1.0 1.3 -2.2 0.8 1.1 -0.8 0.3 -1.1 -2.2 -1.5 -1.9
Medication: Lansoprazole 2.4 2.8 7.2 -1.8 -0.9 -1.8 1.8 1.4 -1.7 1.6 1.9 -1.9 1.5 -1.3 -1.5 -2.7 -1.0
Prospective memory result 0.5 0.6 2.5 0.1 0.0 0.4 -1.2 -1.2 -0.3 -1.5 -0.3 0.1 -1.6 -0.1 -0.6 0.3 -0.6
Lung cancer (father) 0.3 0.3 1.1 -0.5 -0.3 -0.2 -0.5 -0.6 -0.9 -0.6 -0.3 0.2 -1.0 -0.3 -0.5 -0.0 -0.8
Illnesses of mother 3.1 3.8 9.2 -2.1 -2.0 -2.3 1.8 1.8 -2.0 1.4 1.6 -3.0 1.2 -1.9 -1.6 -2.3 -1.8
Forced expiratory volume in 1-second (FEV1), Best measure 1.3 4.3 10.6 -1.7 -3.3 -2.2 2.2 1.5 -2.3 2.8 1.4 -2.5 2.2 -0.7 -1.4 -2.0 -1.3
Pulse wave Arterial Stiffness index 1.6 1.9 3.2 1.3 1.8 1.6 -1.4 -0.7 1.5 -1.4 -0.5 1.8 -0.9 1.3 1.6 1.3 1.5
Impedance of arm (left) 0.3 1.5 4.2 0.8 -0.9 1.0 -1.4 -1.6 0.3 -1.0 -1.7 0.3 -1.3 0.8 2.0 2.0 0.4
Arm fat mass (right) 4.1 16.9 27.9 -4.2 -4.3 -4.8 3.3 3.1 -5.0 3.2 2.8 -4.9 1.7 -4.0 -5.3 -5.1 -4.2
Trunk predicted mass 3.3 19.0 29.1 -3.7 -3.2 -4.9 4.6 4.5 -4.8 4.5 4.4 -5.1 3.6 -3.3 -5.0 -5.4 -3.3
Standing height 2.4 23.8 39.2 -4.0 -5.0 -5.4 5.3 5.2 -5.6 5.4 4.8 -6.3 4.2 -3.4 -4.3 -5.0 -3.6
Length of working week for main job 2.6 2.9 8.0 1.0 0.6 1.0 -2.5 -2.5 0.7 -2.8 -2.2 1.7 -2.4 0.7 0.3 1.3 1.1
Exposure to tobacco smoke at home 1.8 2.0 6.1 1.3 0.3 1.1 -1.9 -2.5 0.9 -1.9 -2.2 1.2 -1.9 0.3 0.6 0.1 0.6
Breastfed as a baby 1.6 2.0 4.5 -1.7 -1.4 -1.9 0.9 0.5 -1.5 0.7 0.7 -2.1 0.3 -1.7 -1.4 -2.0 -0.9
Tense / ‘highly strung’ 0.8 1.4 2.7 1.0 -0.0 1.2 -1.5 -1.3 1.0 -1.5 -0.9 1.6 -1.1 1.3 0.8 1.5 0.7
Seen doctor (GP) for nerves, anxiety, tension or depression 0.9 1.3 4.8 -0.6 -1.0 -0.5 1.4 2.0 -1.0 1.0 2.2 -0.4 1.0 -0.3 -0.9 -0.6 -1.3
Hair/balding pattern: Pattern 4 4.0 9.8 18.6 -3.8 -4.3 -3.8 2.2 1.3 -4.1 2.2 1.8 -3.3 0.9 -3.1 -3.8 -3.3 -3.3
Birth weight of first child 1.4 2.5 5.0 -1.6 -0.8 -1.8 2.1 1.9 -1.0 2.2 1.3 -0.9 2.0 -1.2 -1.4 -1.8 -1.2
Peak expiratory flow (PEF) 0.4 0.9 4.0 0.1 -0.9 -0.4 1.2 1.0 -0.0 1.6 0.9 -0.4 2.0 0.8 0.7 -0.3 0.9
Pulse wave reflection index 0.4 0.5 2.4 0.5 0.8 0.6 0.6 1.0 0.1 0.5 1.6 0.3 0.8 0.5 0.2 0.3 0.4
Ever highly irritable/argumentative for 2 days 1.9 2.3 6.3 2.0 2.5 2.1 -0.5 0.2 0.9 0.1 0.1 2.4 0.2 2.3 1.3 1.4 1.5
Loud music exposure frequency 2.4 2.7 6.2 1.6 1.9 1.5 0.9 1.3 0.9 1.1 1.7 1.5 2.1 2.5 1.8 1.0 2.2
Qualifications: O levels/GCSEs or equivalent 3.7 5.8 9.1 -3.0 -2.5 -2.9 2.2 1.6 -2.7 2.6 1.3 -2.8 0.9 -2.8 -2.7 -2.0 -2.8
Mouth/teeth dental problems: Bleeding gums 1.1 1.4 3.0 1.0 0.5 1.0 -1.5 -1.3 1.1 -1.1 -1.7 1.6 -0.9 1.0 1.4 1.0 1.1
Blood clot in the leg (DVT) 0.1 0.2 0.6 0.6 0.8 0.3 -0.4 -0.4 -0.0 -0.3 -0.2 0.2 -0.3 0.7 0.3 -0.2 0.2
Medication: Paracetamol 0.3 0.6 2.4 -0.8 1.4 -0.5 0.7 0.7 -0.4 0.5 0.5 -0.2 1.0 0.1 -0.2 -1.6 0.2
Headache pain in last month 2.4 4.1 9.3 -1.6 -0.4 -1.6 3.1 3.0 -1.6 3.0 2.3 -2.0 2.9 -1.3 -1.2 -0.9 -0.5
Medication for cholesterol, blood pressure or diabetes 0.4 0.6 1.4 -0.7 -0.2 -1.1 -0.2 -0.8 -0.8 -0.1 -0.7 -1.0 -0.5 -1.2 -1.0 -0.9 -0.6
Glaucoma (self-reported) 1.0 1.2 4.3 0.3 0.7 0.2 -1.7 -2.1 0.2 -1.5 -1.8 0.8 -1.7 -0.1 -0.1 0.0 -0.6
Gout (self-reported) 0.8 1.0 3.7 -1.0 -0.2 -1.2 -0.0 0.3 -1.3 -0.3 -0.4 -1.9 -0.9 -1.4 -1.5 -0.9 -0.9
Hypothyroidism/myxoedema (self-reported) 0.3 0.7 3.4 0.8 1.0 0.8 -0.0 -0.1 1.8 0.0 -0.5 0.6 0.4 0.3 0.6 1.0 1.1
Medication: Amlodipine 2.0 2.8 6.9 2.0 1.6 2.5 -0.1 0.7 2.5 0.0 0.7 2.6 0.3 2.1 1.6 1.8 1.1
Medication: Ventolin 100micrograms inhaler 0.5 0.7 2.4 -0.4 -0.9 -0.9 0.5 0.4 -1.0 0.6 0.1 -1.5 0.2 -1.1 -0.3 -0.7 -1.1
Birth weight 0.3 0.6 2.0 -0.7 -0.2 -1.3 -0.1 -0.3 -1.3 -0.5 -0.4 -1.4 -0.2 -0.9 -0.2 -1.2 -0.2
Chronic bronchitis/emphysema (mother) 0.6 0.7 1.5 1.2 1.1 1.0 -0.8 -0.1 0.4 -0.9 -0.3 0.9 -0.7 0.9 0.8 1.1 0.3
High blood pressure (siblings) 1.6 2.3 4.1 1.9 1.7 2.0 -1.4 -1.2 1.8 -1.6 -0.9 1.9 -0.9 1.3 1.4 1.8 1.0
Forced vital capacity (FVC), Best measure 1.8 6.5 13.9 -1.9 -2.9 -2.5 3.1 2.4 -2.1 3.7 2.3 -3.1 3.1 -0.9 -1.6 -2.8 -1.8
Body fat percentage 3.0 11.9 20.2 -3.5 -4.4 -4.0 2.4 2.0 -4.5 2.2 1.7 -4.0 0.7 -3.4 -4.5 -4.1 -4.0
Leg fat percentage (right) 2.0 7.4 15.6 -2.8 -2.9 -3.3 1.8 1.6 -3.2 1.6 1.3 -2.9 0.5 -3.0 -3.9 -3.6 -3.1
Arm fat-free mass (right) 3.8 19.3 30.8 -4.0 -3.3 -5.0 4.5 4.4 -4.8 4.3 4.4 -5.0 3.4 -3.5 -5.2 -5.5 -3.4
Exposure to tobacco smoke outside home 1.1 1.5 4.5 0.8 -0.1 0.8 -1.3 -1.8 1.1 -1.1 -2.1 1.4 -1.1 0.7 1.0 1.1 1.5
Comparative body size at age 10 1.0 2.6 7.2 -2.4 -0.7 -1.9 1.3 1.7 -2.7 1.2 1.3 -1.5 0.5 -1.6 -2.1 -1.0 -1.5
Number of full brothers 1.1 1.4 4.0 0.7 0.8 0.7 -1.3 -1.4 1.5 -0.9 -1.7 0.6 -0.4 0.9 2.0 -0.0 1.7
Worry too long after embarrassment 1.5 2.5 6.5 1.5 1.3 1.9 -0.7 -0.5 1.7 -0.7 -0.5 2.5 0.2 2.0 2.2 1.6 2.5
Seen a psychiatrist for nerves, anxiety, tension or depression 0.4 0.6 2.7 -0.3 0.6 -0.1 0.7 1.0 -0.4 0.5 1.6 -0.2 0.8 0.0 -0.6 -1.2 -0.5
Wheeze or whistling in the chest in last year 0.3 0.5 4.8 0.1 2.2 0.1 -0.7 -0.3 0.2 -0.9 -0.3 -0.0 -0.8 -0.3 0.2 0.0 -0.1
Number of children fathered 0.1 0.1 0.4 -0.2 -0.3 -0.5 -0.1 0.1 0.1 -0.3 -0.0 0.4 -0.2 0.6 0.1 -0.6 0.5
Reason for reducing amount of alcohol drunk: Health precaution 4.5 5.3 11.2 2.7 0.9 2.6 -1.9 -1.6 2.5 -1.8 -1.5 2.3 -0.6 2.9 3.4 2.5 3.1
Age at first live birth 0.2 0.4 1.6 -0.3 -0.1 -0.6 -1.0 -0.8 -0.7 -0.8 -0.5 0.2 -1.3 -0.4 -0.3 0.5 -0.2
Pulse wave peak to peak time 2.9 3.4 6.1 -1.7 -2.1 -2.2 1.9 1.1 -1.9 1.9 0.9 -2.5 1.2 -1.8 -2.0 -2.0 -1.9
Health satisfaction 0.9 1.2 2.9 1.3 0.8 1.1 -0.7 -1.1 1.3 -0.3 -1.0 1.6 -0.0 1.7 1.3 1.0 1.1
Shortness of breath walking on level ground 0.6 0.7 2.4 1.2 1.6 1.3 -0.1 -0.0 0.9 -0.0 0.1 0.9 0.3 1.1 0.8 0.4 1.0
Qualifications: College or University degree 1.2 3.7 8.1 -2.4 -1.5 -2.8 1.0 0.6 -2.2 1.1 0.7 -2.5 0.1 -2.1 -2.6 -2.4 -2.2
Eye problems/disorders: None of the above 1.6 1.8 5.2 -0.5 -0.6 -0.2 2.1 2.2 0.0 2.2 2.3 -0.6 2.2 -0.0 -0.0 0.1 0.5
Mouth/teeth dental problems: Loose teeth 2.6 3.1 6.5 -1.9 -2.5 -2.2 1.0 0.5 -2.0 1.1 0.4 -1.6 0.4 -1.9 -2.4 -2.5 -1.7
Emphysema/chronic bronchitis 0.5 0.6 1.4 -0.2 -0.4 -0.2 -1.0 -0.9 0.4 -1.2 -1.1 0.4 -1.2 -0.5 0.6 -0.7 -0.5
Medication for pain relief, constipation, heartburn 0.7 1.2 3.7 -1.3 -1.7 -1.3 0.4 0.1 -1.3 0.5 0.3 -1.0 -0.4 -1.3 -1.5 -0.2 -1.9
Neck or shoulder pain in last month 0.8 1.1 3.4 -0.5 1.2 -0.6 1.3 1.8 0.0 1.2 0.9 -0.3 1.6 -0.4 -0.7 -1.5 0.0
Medication: Blood pressure 1.0 1.7 3.4 0.9 0.6 1.5 1.0 1.6 1.0 1.0 1.7 1.4 1.6 1.9 1.2 1.1 1.1
Angina (self-reported) 0.7 0.9 3.5 -0.9 0.2 -0.9 0.8 0.5 0.2 0.5 1.2 -1.6 0.6 -0.7 -0.2 -1.9 -1.1
Migraine (self-reported) 0.4 0.5 1.6 0.5 0.2 0.9 0.3 0.5 0.7 0.5 -0.1 1.1 0.1 0.6 0.5 1.3 1.2
Medication: Ibuprofen 0.6 0.7 1.8 0.8 1.4 0.6 0.4 0.5 1.0 0.5 0.4 0.1 1.0 0.9 1.2 0.6 1.3
Medication: Allopurinol 0.5 0.6 1.6 -0.4 0.5 -0.7 -0.4 -0.4 -0.6 -0.8 -0.8 -1.3 -0.9 -0.9 -1.0 -1.1 -0.3
Medication: Omeprazole 2.2 2.6 7.6 -0.7 1.5 -0.5 2.4 2.6 1.2 2.2 2.4 -0.7 2.8 -0.2 0.1 -0.9 0.7
Medication: Seretide 50 evohaler 0.2 0.3 0.8 -0.0 -0.3 -0.0 -0.6 -0.9 -0.6 -0.9 -0.4 -0.2 -0.9 -0.5 0.0 -0.1 -0.5
Mean time to correctly identify matches 0.6 1.1 2.8 1.4 -1.0 1.4 -0.7 -1.2 0.9 -0.6 -1.0 0.8 -0.5 1.4 0.9 1.7 0.7
Heart disease (mother) 0.1 0.2 0.4 0.5 -0.4 0.6 -0.3 -0.7 -0.1 -0.4 -0.3 0.3 -0.2 0.2 0.3 0.6 0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.4 0.4 1.3 0.4 0.7 0.4 -0.7 -0.5 1.1 -1.1 -0.7 0.3 -0.6 0.1 0.4 0.3 0.8
Whole body fat mass 4.6 19.2 31.0 -4.4 -5.1 -5.1 3.4 3.1 -5.6 3.3 2.8 -5.2 1.6 -4.2 -5.6 -5.3 -4.6
Leg fat mass (right) 4.1 16.0 28.8 -4.1 -4.1 -4.8 3.3 3.0 -4.7 3.0 2.6 -4.4 1.6 -4.1 -5.4 -5.1 -4.1
Arm predicted mass (right) 3.6 18.6 30.5 -4.0 -3.4 -5.0 4.2 4.2 -4.9 4.1 4.1 -5.0 3.1 -3.5 -5.1 -5.5 -3.5
Pulse rate, automated reading 0.7 2.2 7.8 0.2 1.0 0.7 -2.3 -1.8 1.1 -2.8 -1.9 1.2 -2.5 -0.2 0.3 -0.0 0.1
Alcohol intake frequency. 1.9 4.5 9.2 -1.2 -2.6 -1.3 2.8 2.6 -2.2 3.0 2.2 -2.1 2.5 -0.8 -2.1 -1.4 -1.2
Comparative height size at age 10 4.8 26.2 39.7 -4.2 -5.1 -4.9 6.3 6.0 -5.4 6.3 5.4 -5.3 5.1 -3.1 -4.9 -4.9 -3.9
Number of full sisters 0.4 0.4 2.2 -0.3 -0.7 -0.5 0.5 0.4 -0.4 -0.1 -0.1 -1.5 0.1 -1.5 -0.3 -0.5 -0.0
Suffer from ‘nerves’ 0.3 0.4 1.0 -0.1 0.9 0.2 0.3 1.0 0.5 0.7 0.7 0.3 0.8 1.0 0.6 -0.2 0.7
Overall health rating 0.2 0.4 1.7 0.5 -0.0 0.7 -0.9 -0.7 0.5 -1.3 -0.6 0.6 -1.0 -0.0 0.1 0.5 0.4
Chest pain or discomfort 0.5 0.8 1.6 1.0 0.3 1.2 -1.0 -0.6 0.6 -0.7 -0.4 0.9 -0.7 1.2 1.3 0.8 0.8
Had major operations 0.4 0.5 1.8 -1.0 -0.2 -0.9 0.3 0.4 -0.4 0.3 0.4 -1.4 0.3 -0.7 -0.1 -0.9 -0.7
Age at last live birth 3.0 4.4 9.1 1.6 1.3 1.3 -3.0 -2.8 1.8 -2.7 -2.7 2.4 -2.6 1.2 1.5 1.8 1.6
Family relationship satisfaction 1.6 2.0 4.1 1.5 0.8 1.5 -1.6 -1.1 1.1 -1.3 -1.5 2.0 -1.1 2.0 1.2 1.1 1.2
Leg pain on walking 0.8 1.0 2.5 1.0 1.6 0.9 -0.9 -0.8 1.3 -1.0 -1.1 1.2 -0.4 0.6 0.9 0.5 1.3
Qualifications: NVQ or HND or HNC or equivalent 1.0 1.2 3.9 -0.2 -1.4 -0.0 -1.5 -2.0 -0.3 -1.4 -1.6 0.0 -2.0 -0.8 -0.2 -0.2 -0.5
Commuting to job workplace: Car/motor vehicle 0.3 0.4 0.9 -0.4 0.0 -0.6 0.7 0.4 -0.5 0.6 0.9 -0.8 0.5 -0.5 -0.8 -0.5 -0.5
Illness, injury, bereavement, stress in last 2 years 0.4 0.5 1.4 0.8 -0.2 0.4 0.7 0.8 0.3 0.7 0.2 0.2 1.0 0.8 0.7 1.2 0.7
Medication: Aspirin 2.8 3.7 8.5 2.3 1.0 2.2 -1.9 -1.6 2.4 -1.7 -1.5 1.7 -0.8 2.1 2.9 1.7 2.2
Supplements: Vitamin C 1.0 1.2 3.8 1.1 1.9 0.5 -1.4 -1.4 1.1 -1.5 -0.9 0.4 -1.4 -0.3 0.8 0.0 0.2
Knee pain experienced in last month 0.2 0.3 1.1 0.9 0.3 0.5 0.1 1.0 -0.7 -0.3 0.4 -0.4 0.0 -0.2 -0.4 -0.5 -0.0
Hypertension (Self-reported) 2.0 5.5 12.7 2.7 1.9 3.2 -0.6 0.5 3.6 -0.8 0.8 3.4 0.5 3.4 2.7 2.3 2.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.1 0.1 0.4 0.1 -0.6 -0.1 0.4 0.7 -0.3 0.2 0.1 0.3 0.0 -0.6 -0.3 -0.2 -0.3
Illnesses of father: Heart disease 0.7 0.9 2.9 1.1 1.5 1.1 -0.3 0.0 1.7 -0.1 -0.6 1.2 0.0 1.2 0.8 0.6 1.1
Illnesses of siblings: Diabetes 0.2 0.3 1.0 0.7 0.6 0.8 -0.1 -0.5 0.9 -0.1 -0.6 0.5 0.1 0.3 0.1 1.0 -0.2
Smoking status: Previous 0.3 0.5 4.8 -0.5 2.2 -0.5 -0.0 -0.2 0.5 -0.1 -0.3 0.0 0.5 -0.5 0.3 -0.7 0.3
Forced expiratory volume in 1-second (FEV1), predicted 2.3 4.8 11.0 -1.6 -1.3 -1.8 2.9 2.8 -2.2 3.3 3.1 -2.5 2.8 -0.6 -1.3 -1.2 -0.6
Whole body fat-free mass 3.6 20.9 32.4 -4.1 -3.8 -5.2 4.6 4.5 -5.1 4.5 4.3 -5.4 3.3 -3.7 -5.4 -5.7 -3.7
Leg fat-free mass (right) 3.8 20.1 28.9 -4.3 -4.1 -5.2 4.3 4.2 -5.2 4.1 4.0 -5.4 2.8 -3.9 -5.3 -5.4 -3.8
Arm fat percentage (left) 2.5 10.1 18.4 -3.4 -3.7 -3.8 2.1 1.9 -4.0 2.1 1.5 -3.7 0.6 -3.3 -4.3 -3.9 -3.6
Average weekly red wine intake 1.6 2.4 6.2 -1.6 -0.1 -2.0 0.6 0.3 -1.5 0.2 1.0 -2.3 -0.2 -2.2 -2.5 -1.4 -2.0
Handedness (chirality/laterality): Left-handed 0.5 0.6 2.0 1.4 0.7 1.2 -1.0 -0.6 -0.2 -0.9 -0.5 0.6 -0.7 1.1 0.1 0.9 0.1
Mood swings 0.9 1.6 6.6 1.7 1.1 1.8 -0.1 0.3 0.7 0.2 0.8 2.4 0.4 2.6 0.2 0.6 0.6
Loneliness, isolation 0.7 1.0 4.0 1.3 0.6 1.4 -0.4 -0.1 0.8 -0.4 0.4 1.8 -0.2 2.0 0.6 0.4 1.0
Long-standing illness, disability or infirmity 0.4 0.6 2.1 -0.1 0.0 -0.3 1.0 1.4 0.6 0.9 0.9 -0.5 1.4 -0.1 0.5 -0.8 0.7
Ever had bowel cancer screening 0.4 0.4 1.2 -1.0 -0.0 -1.1 0.7 0.5 -0.4 0.2 0.5 -0.8 0.5 -1.0 -0.4 -0.2 -0.7
Diabetes diagnosed by doctor 0.2 0.3 1.2 0.1 0.1 -0.1 0.5 1.1 -0.1 0.2 0.9 -0.8 0.2 -0.7 -0.6 0.3 -0.6
Ever had stillbirth, spontaneous miscarriage or termination 0.4 0.4 1.3 0.1 0.0 -0.1 -0.8 -1.0 -0.5 -0.9 -1.2 0.8 -0.9 -0.4 -0.1 -0.4 0.0
Friendships satisfaction 0.3 0.3 1.3 0.1 0.6 0.1 -0.7 -0.3 0.6 -0.3 -0.4 0.7 -0.2 1.1 0.8 -0.3 0.6
Qualifications: nursing, teaching 0.8 1.3 4.3 -2.0 -1.2 -2.1 1.0 0.3 -0.5 1.3 0.2 -1.2 0.6 -1.1 -0.5 -1.2 -0.8
Commuting to job workplace: Walk 1.1 1.2 3.1 -1.0 -1.5 -1.4 -0.1 -0.8 -0.7 -0.4 -1.0 -1.2 -0.8 -1.8 -1.3 -1.2 -1.0
Eye problems/disorders: Cataract 1.8 2.1 4.8 1.1 2.1 0.7 -2.1 -2.2 0.2 -2.2 -2.0 0.7 -2.1 0.1 0.7 0.8 0.3
Mouth/teeth dental problems: Mouth ulcers 0.4 0.6 1.9 -0.7 1.1 -0.7 -0.7 -0.6 0.2 -1.4 -0.4 -0.6 -0.6 -0.9 0.3 -1.2 0.2
Medication for cholesterol 1.9 2.8 10.9 -2.3 -2.0 -1.8 1.2 0.7 -3.3 1.7 0.7 -2.0 0.5 -1.5 -1.5 -1.0 -1.2
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.3 0.4 1.2 -0.8 1.1 -0.3 -0.4 -0.7 0.7 -0.5 -0.5 -0.3 -0.6 -0.9 -0.0 -0.7 0.1
Back pain experienced in last month 0.4 0.5 1.8 -0.4 0.6 -0.7 -0.1 -0.0 -0.4 -0.6 -0.4 -0.5 -0.4 -1.4 -1.0 -1.1 -1.1
Mineral and other dietary supplements 1.6 2.2 5.1 -2.1 -1.2 -2.3 1.4 1.1 -1.6 1.6 1.3 -1.7 1.0 -0.5 -1.5 -1.3 -1.0
Breast cancer (self-reported) 0.3 0.3 1.0 0.9 1.0 0.9 0.1 -0.2 0.7 -0.0 -0.2 0.8 0.4 0.6 0.3 0.4 0.5
Asthma (self-reported) 0.3 0.6 1.4 -0.1 0.8 0.0 -1.0 -0.9 0.6 -1.2 -0.9 -0.7 -1.0 -0.8 0.8 0.2 0.1
Osteoporosis (self-reported) 0.5 0.6 2.6 -0.9 0.1 -1.0 0.5 0.3 -1.1 0.5 0.5 -0.7 0.4 -0.8 -1.0 -1.6 -0.5
Osteoarthritis (self-reported) 0.6 0.8 2.5 -0.7 1.4 -0.6 1.0 1.6 -0.1 0.6 1.2 -0.0 1.4 -0.2 -0.1 -1.0 0.4
Medication: Aspirin 1.8 2.3 5.2 1.9 0.5 1.8 -1.6 -1.4 1.5 -1.5 -1.2 1.4 -0.8 1.7 2.3 1.5 1.5
Medication: Gliclazide 0.2 0.3 0.9 -0.0 0.1 -0.2 0.3 0.7 -0.8 -0.0 0.6 -0.3 -0.1 -0.8 -1.0 -0.5 -0.4
Illnesses of father: None of the above (group 1) 0.2 0.2 1.0 -0.3 -1.0 -0.3 0.3 -0.4 -0.4 0.3 0.4 -0.1 0.0 -0.6 -0.0 0.9 -0.3
Smoking status: Current 0.6 1.0 3.3 -0.7 -0.5 -0.8 0.2 -0.3 -0.8 -0.1 0.2 -1.4 -0.7 -1.5 -1.5 -1.2 -1.8
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.2 0.4 1.3 -0.6 -0.1 -0.6 0.6 0.1 0.4 1.0 0.2 -0.5 1.1 0.2 0.3 -0.9 -0.2
Whole body water mass 3.7 21.2 33.3 -4.2 -3.7 -5.3 4.5 4.5 -5.2 4.4 4.3 -5.5 3.2 -3.8 -5.4 -5.8 -3.8
Leg predicted mass (right) 3.8 20.5 29.9 -4.3 -4.1 -5.2 4.3 4.2 -5.2 4.2 4.0 -5.5 2.9 -3.9 -5.4 -5.4 -3.9
Arm fat mass (left) 4.3 17.8 29.4 -4.4 -4.3 -5.0 3.5 3.1 -5.1 3.4 2.8 -5.0 1.9 -4.0 -5.4 -5.3 -4.2
Number of self-reported non-cancer illnesses 0.2 0.4 1.5 0.1 0.2 0.1 0.8 1.2 0.7 0.4 1.0 0.3 1.0 0.3 0.2 -0.7 0.1
Average weekly champagne plus white wine intake 0.6 0.8 1.7 0.7 0.1 0.9 -0.9 -0.7 1.2 -0.7 -0.5 1.3 -0.5 0.9 0.9 1.2 0.9
Miserableness 0.7 1.3 4.7 0.7 0.4 1.5 -0.4 0.4 1.2 -0.3 0.8 2.0 -0.1 2.2 1.0 0.8 1.4
Guilty feelings 2.0 3.0 6.8 2.3 1.8 2.5 -0.8 -0.2 1.0 -0.6 0.1 2.4 0.2 2.6 1.8 2.3 2.1
Wears glasses or contact lenses 0.7 0.8 2.0 -0.5 -0.7 -0.6 1.3 1.0 0.1 1.3 1.3 -0.6 1.4 0.1 0.2 -1.2 -0.5
Ever taken oral contraceptive pill 2.8 3.1 6.8 2.1 2.3 2.4 -0.4 -0.4 1.6 0.1 0.0 2.3 0.4 2.6 1.9 2.1 2.2
Hearing aid user 0.1 0.1 0.9 0.2 0.9 -0.1 0.2 -0.2 -0.4 0.1 -0.0 -0.2 0.4 0.2 0.2 0.3 -0.6
Mother’s age at death 0.6 0.8 2.0 -1.2 -0.1 -1.0 -0.3 -0.2 -1.0 -0.5 -0.1 -0.5 -1.1 -1.2 -1.4 -0.9 -1.3
Financial situation satisfaction 2.1 2.6 4.8 0.9 1.5 1.4 -2.2 -1.7 2.1 -1.8 -2.1 1.4 -1.8 1.1 1.8 1.0 1.1
Tinnitus: Yes, now most or all of the time 0.8 0.9 2.5 1.2 1.3 1.0 -0.2 0.2 1.0 -0.0 -0.5 1.6 0.4 1.1 0.9 1.0 1.0
Commuting to job workplace: Public transport 0.2 0.3 0.9 0.4 -0.2 0.4 -0.8 -0.9 0.1 -0.8 -0.4 0.1 -0.9 0.3 0.3 -0.1 -0.3
Eye problems/disorders: Glaucoma 0.6 0.7 2.7 0.1 0.4 0.0 -1.1 -1.5 0.4 -0.9 -1.6 0.7 -1.0 -0.2 -0.5 -0.4 -0.5
Medication: Blood pressure 1.0 1.8 10.4 1.4 1.4 1.4 -0.5 -0.3 3.2 -1.0 -0.0 1.6 0.0 1.3 1.2 0.6 1.3
Pain type(s) experienced in last month: Hip pain 0.5 0.6 3.3 -0.1 -0.7 -0.9 0.1 0.5 -0.4 -0.2 -0.4 -0.8 0.1 -1.0 -0.7 -1.8 -0.9
Supplements: Fish oil (including cod liver oil) 2.1 2.7 5.2 2.3 1.2 2.2 -1.7 -1.9 2.0 -1.6 -1.6 1.7 -1.1 0.7 1.8 1.3 1.3
High cholesterol (Self-reported) 0.1 0.1 0.9 -0.1 -1.0 0.2 0.1 0.1 -0.0 -0.1 0.3 0.2 0.1 -0.1 0.0 0.5 -0.5
Medication: Bendroflumethiazide 0.5 0.8 3.0 0.7 0.1 0.6 1.3 0.6 1.1 0.9 1.5 0.2 1.7 0.4 -0.1 -0.7 -0.0
Medication: Paracetamol 0.6 1.0 2.5 -1.3 1.2 -0.9 1.1 1.3 -0.3 1.0 0.9 -0.5 1.6 -0.1 -0.0 -1.6 0.4
Medication: Lisinopril 1.2 1.6 4.3 1.4 1.9 1.3 -0.6 0.0 2.0 -0.7 0.1 1.3 -0.1 1.6 1.1 0.6 2.1
Medication: Atorvastatin 1.1 1.4 3.1 -1.8 -0.3 -1.5 1.4 1.4 0.5 1.1 1.5 -1.5 1.3 -0.9 -0.2 -1.1 -0.6
Illnesses of father: High blood pressure 1.3 1.6 2.5 1.2 1.5 1.5 -1.3 -0.7 1.0 -1.1 -1.1 1.6 -0.9 1.4 1.3 1.4 1.3
Alcohol drinker status: Never 0.8 0.9 1.6 -1.2 -0.4 -1.1 1.1 0.7 -0.5 1.3 0.5 -1.0 0.9 -1.1 -1.2 -1.2 -0.8
Ever smoked 0.5 0.8 2.8 -1.1 0.9 -1.3 -0.4 -0.8 0.3 -0.6 -0.8 -1.0 -0.2 -1.3 0.1 -1.7 -0.4
Basal metabolic rate 4.4 24.2 36.8 -4.5 -4.3 -5.6 4.8 4.6 -5.6 4.7 4.4 -5.9 3.3 -4.2 -5.9 -6.1 -4.2
Leg fat percentage (left) 2.0 7.4 16.2 -2.8 -2.8 -3.2 1.8 1.6 -3.3 1.6 1.4 -2.9 0.5 -3.0 -4.0 -3.5 -3.1
Arm fat-free mass (left) 4.0 20.5 32.4 -4.2 -3.9 -5.2 4.4 4.4 -5.1 4.2 4.2 -5.2 3.1 -3.9 -5.5 -5.7 -3.8
Number of operations (self-reported) 0.9 1.3 2.8 -1.4 0.3 -1.4 1.1 1.2 -1.2 0.9 1.6 -1.7 1.2 -0.9 -0.6 -1.1 -0.7
Average weekly beer plus cider intake 1.0 1.5 3.0 1.0 0.3 1.2 -1.6 -1.3 0.1 -1.6 -0.9 1.3 -1.6 1.1 1.3 1.7 0.7
Irritability 4.1 6.9 15.8 4.0 2.7 3.8 -1.9 -1.0 2.8 -1.6 -0.7 3.8 -0.9 3.6 2.3 2.2 2.2
Risk taking 2.2 3.2 8.0 1.9 2.8 1.9 -1.5 -1.5 2.6 -1.4 -1.1 2.0 -0.6 1.4 1.7 1.2 2.1
Ever had prostate specific antigen (PSA) test 1.1 1.3 4.5 -1.2 -2.1 -1.3 0.1 0.1 -1.8 0.2 -0.1 -1.0 -0.5 -0.9 -1.1 -0.8 -1.8
Fractured/broken bones in last 5 years 0.4 0.6 1.6 0.7 1.2 0.3 -1.0 -0.7 -0.0 -1.2 -1.3 0.2 -1.1 -0.2 0.1 0.3 0.2
Age started oral contraceptive pill 0.4 0.5 5.0 -0.6 -2.2 -0.1 0.2 0.5 -0.0 0.1 1.0 -0.6 0.0 0.3 0.6 0.2 -0.2
Diastolic blood pressure, automated reading 0.7 2.2 5.1 1.2 1.5 1.4 -2.0 -1.5 1.0 -2.2 -1.4 2.3 -1.2 1.2 1.2 0.3 1.2
Ever depressed for a whole week 1.9 2.3 7.5 -0.2 0.2 0.2 2.0 2.7 -0.5 2.4 2.7 0.5 2.2 1.1 -0.8 -0.8 -0.5
Unable to work because of sickness or disability 0.3 0.4 1.0 -0.2 -0.6 -0.3 -0.2 0.2 -0.8 -0.6 0.1 -0.9 -0.8 -0.8 -0.8 -0.6 -1.0
Commuting to job workplace: Cycle 0.3 0.3 1.5 -0.8 -0.6 -0.7 0.4 -0.1 -0.1 0.4 -0.1 0.2 0.0 -0.7 -0.5 -1.2 -0.8
Myopia 0.2 0.4 1.1 -0.8 0.8 -0.5 0.7 0.3 -0.2 0.6 0.7 -1.0 0.6 -0.6 -0.1 -0.4 -0.4
Vascular/heart problems diagnosed by doctor 1.5 4.2 11.8 -2.5 -1.9 -2.7 0.3 -0.5 -3.4 0.5 -0.8 -2.7 -0.9 -3.0 -2.4 -1.4 -2.1
Cholesterol lowering medication 0.4 0.5 3.0 0.5 1.7 -0.1 -0.0 -0.3 1.7 -0.5 -0.4 0.1 0.4 -0.8 0.0 -0.3 0.2
Medication: Omeprazole (e.g. Zanprol) 2.1 2.5 6.3 -1.0 0.9 -0.9 2.4 2.4 0.4 2.1 2.2 -1.4 2.5 -0.8 -0.7 -1.3 0.2
Pain experienced in last month 0.5 0.9 4.3 -1.4 -2.1 -0.9 -0.4 -1.3 -0.6 -0.0 -0.6 -0.4 -1.0 -0.4 -0.7 -0.4 -0.9
Supplements: Calcium 0.3 0.3 1.2 -0.4 -0.3 -0.5 -0.1 -0.3 -0.8 -0.5 0.1 -0.7 -0.4 -1.1 -0.6 0.2 -0.4
Basal cell carcinoma (self-reported) 0.9 1.0 5.2 0.7 2.3 0.5 -0.5 -0.8 1.6 -0.7 -1.0 0.7 0.0 0.2 1.3 0.5 1.0
Heart attack/myocardial infarction (self-reported) 0.1 0.2 0.7 0.4 0.4 0.2 -0.4 -0.2 0.4 -0.6 -0.2 -0.6 -0.1 -0.2 0.5 -0.8 -0.3
Deep venous thrombosis (DVT) (self-reported) 0.1 0.1 0.4 0.1 0.5 -0.2 0.1 0.1 -0.5 0.1 0.2 -0.3 0.1 0.3 -0.1 -0.7 -0.2
Heart disease (siblings) 0.3 0.4 0.8 0.2 0.7 -0.1 0.7 0.7 -0.4 0.7 0.5 -0.2 0.7 -0.5 -0.9 -0.9 -0.7
Alcohol drinker status: Previous 1.1 1.2 3.3 -0.9 -0.6 -1.1 1.1 1.1 -1.8 1.0 1.3 -1.8 0.8 -0.5 -1.1 -0.5 -0.8
Pack years of smoking 1.5 2.2 8.0 -1.4 -2.0 -1.6 1.4 1.0 -0.6 1.7 1.1 -1.4 1.3 -0.5 -1.0 -2.8 -1.0
Impedance of whole body 0.5 2.7 6.5 1.5 -0.4 1.8 -1.7 -1.9 1.0 -1.4 -2.0 1.1 -1.4 1.3 2.5 2.5 0.9
Leg fat mass (left) 4.0 15.7 28.7 -4.1 -4.0 -4.7 3.2 3.0 -4.7 2.9 2.6 -4.5 1.5 -4.0 -5.4 -5.0 -4.0
Arm predicted mass (left) 4.0 20.4 32.5 -4.3 -3.9 -5.2 4.5 4.3 -5.0 4.2 4.1 -5.2 3.2 -3.8 -5.4 -5.7 -3.6