[Hub]/) : Traits : Leg fat mass (left) :

chr16:1,381,714-2,952,423

Best TWAS P=2.34e-11 · Best GWAS P=1.19e-12 conditioned to 0.563

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex SLC9A3R2 0.15 0.09 enet 7 0.10 7.8e-12 -5.2 5.8 6.9e-09 -0.58 0.26 0.74 FALSE
2 METSIM Adipose PKD1 0.06 0.02 bslmm 370 0.03 9.5e-06 -6.3 5.1 3.1e-07 -0.77 0.01 0.99 FALSE
3 ROSMAP Brain Pre-frontal Cortex SLC9A3R2 0.16 0.11 lasso 6 0.12 6.3e-15 -6.5 6.3 2.7e-10 -0.61 0.10 0.90 FALSE
4 ROSMAP Brain Pre-frontal Cortex MLST8 0.22 0.18 lasso 6 0.18 7.1e-23 4.8 5.5 3.1e-08 -0.47 1.00 0.00 FALSE
5 YFS Blood MLST8 0.12 0.06 bslmm 326 0.06 4.3e-20 -3.9 5.5 2.9e-08 -0.37 1.00 0.00 FALSE
6 The Cancer Genome Atlas Brain Lower Grade Glioma CASKIN1 0.02 0.00 blup 38 0.01 4.5e-02 4.5 -6.2 4.9e-10 0.45 0.03 0.04 TRUE
7 The Cancer Genome Atlas Prostate Adenocarcinoma C16orf79 0.05 0.01 lasso 4 0.02 1.5e-03 4.5 -5.4 7.2e-08 0.23 0.01 0.92 FALSE
8 The Cancer Genome Atlas Thyroid Carcinoma CASKIN1 0.06 0.02 blup 38 0.04 1.5e-04 -7.0 -6.0 2.1e-09 0.80 0.00 0.97 FALSE
9 The Cancer Genome Atlas Thyroid Carcinoma MLST8 0.09 0.07 enet 8 0.09 9.9e-09 5.2 5.4 5.4e-08 -0.29 0.00 1.00 FALSE
10 The Cancer Genome Atlas Thyroid Carcinoma SLC9A3R2 0.06 0.03 lasso 5 0.03 3.7e-04 -5.2 6.7 2.3e-11 -0.59 0.09 0.65 TRUE