[Hub]/) : Traits : Leg fat mass (left) : ← →

chr16:1,381,714-2,952,423

Best TWAS P=2.34e-11 · Best GWAS P=1.19e-12 conditioned to 0.563

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
10	The Cancer Genome Atlas	Thyroid Carcinoma	SLC9A3R2	0.06	0.03	lasso	5	0.03	3.7e-04	-5.2	6.7	2.3e-11	-0.59	0.09	0.65	TRUE
6	The Cancer Genome Atlas	Brain Lower Grade Glioma	CASKIN1	0.02	0.00	blup	38	0.01	4.5e-02	4.5	-6.2	4.9e-10	0.45	0.03	0.04	TRUE
3	ROSMAP	Brain Pre-frontal Cortex	SLC9A3R2	0.16	0.11	lasso	6	0.12	6.3e-15	-6.5	6.3	2.7e-10	-0.61	0.10	0.90	FALSE
8	The Cancer Genome Atlas	Thyroid Carcinoma	CASKIN1	0.06	0.02	blup	38	0.04	1.5e-04	-7.0	-6.0	2.1e-09	0.80	0.00	0.97	FALSE
1	CommonMind	Brain Pre-frontal Cortex	SLC9A3R2	0.15	0.09	enet	7	0.10	7.8e-12	-5.2	5.8	6.9e-09	-0.58	0.26	0.74	FALSE
5	YFS	Blood	MLST8	0.12	0.06	bslmm	326	0.06	4.3e-20	-3.9	5.5	2.9e-08	-0.37	1.00	0.00	FALSE
4	ROSMAP	Brain Pre-frontal Cortex	MLST8	0.22	0.18	lasso	6	0.18	7.1e-23	4.8	5.5	3.1e-08	-0.47	1.00	0.00	FALSE
9	The Cancer Genome Atlas	Thyroid Carcinoma	MLST8	0.09	0.07	enet	8	0.09	9.9e-09	5.2	5.4	5.4e-08	-0.29	0.00	1.00	FALSE
7	The Cancer Genome Atlas	Prostate Adenocarcinoma	C16orf79	0.05	0.01	lasso	4	0.02	1.5e-03	4.5	-5.4	7.2e-08	0.23	0.01	0.92	FALSE
2	METSIM	Adipose	PKD1	0.06	0.02	bslmm	370	0.03	9.5e-06	-6.3	5.1	3.1e-07	-0.77	0.01	0.99	FALSE